Effects of CaMKII inhibitor tatCN21 on activity-dependent redistribution of CaMKII in hippocampal neurons

Neuroscience

Volumn 244, Issue , 2013, Pages 188-196

  Tao Cheng, J H ^a   Yang, Y ^a   Bayer, K U ^b   Reese, T S ^a   Dosemeci, A ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

CaMKII inhibitor; Electron microscopy; Polyribosomes; PSD; Synapse; TatCN21

Indexed keywords

CALCIUM; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; N [2 [[N [3 (4 CHLOROPHENYL) 2 PROPENYL] N METHYLAMINO]METHYL]PHENYL] N (2 HYDROXYETHYL) 4 METHOXYBENZENESULFONAMIDE; N METHYL DEXTRO ASPARTIC ACID; POTASSIUM ION; PROTEIN KINASE INHIBITOR; TATCN21; UNCLASSIFIED DRUG;

ARTICLE; BIOACCUMULATION; ENZYME LOCALIZATION; HIPPOCAMPUS; INCUBATION TIME; NERVE CELL; POLYSOME; POSTSYNAPTIC DENSITY; PRIORITY JOURNAL; PROTEIN AGGREGATION;

ANIMALS; BENZYLAMINES; CALCIUM; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CARRIER PROTEINS; CELLS, CULTURED; DENDRITES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; HIPPOCAMPUS; N-METHYLASPARTATE; NEURONS; PEPTIDE FRAGMENTS; POLYRIBOSOMES; POST-SYNAPTIC DENSITY; POTASSIUM; PROTEIN KINASE INHIBITORS; RATS; SULFONAMIDES;

EID: 84878481217     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2013.03.063     Document Type: Article

References (26)

1. Ashpole N.M., Hudmon A. Excitotoxic neuroprotection and vulnerability with CaMKII inhibition. Mol Cell Neurosci 2011, 46:720-730.
2. Ashpole N.M., Song W., Brustovetsky T., Engleman E.A., Brustovetsky N., Cummins T.R., Hudmon A. Calcium/calmodulin-dependent protein kinase II (CaMKII) inhibition induces neurotoxicity via dysregulation of glutamate/calcium signaling and hyperexcitability. J Biol Chem 2012, 287:8495-8506.
3. Buard I., Coultrap S.J., Freund R.K., Lee Y.S., Dell'Acqua M.L., Silva A.J., Bayer K.U. CaMKII "autonomy" is required for initiating but not for maintaining neuronal long-term information storage. J Neurosci 2010, 30:8214-8220.
4. Chang B.H., Mukherji S., Soderling T.R. Characterization of a calmodulin kinase II inhibitor protein in brain. Proc Natl Acad Sci U S A 1998, 95:10890-10895.
5. Chang B.H., Mukherji S., Soderling T.R. Calcium/calmodulin-dependent protein kinase II inhibitor protein: localization of isoforms in rat brain. Neuroscience 2001, 102:767-777.
6. Coultrap S.J., Bayer K.U. CaMKII regulation in information processing and storage. Trends Neurosci 2012, 35:607-618.
7. Dosemeci A., Reese T.S., Petersen J., Tao-Cheng J.-H. A novel particulate form of Ca(2+)/calmodulin-dependent protein kinase II in neurons. J Neurosci 2000, 20:3076-3084.
8. Dosemeci A., Tao-Cheng J.-H., Vinade L., Winters C.A., Pozzo-Miller L., Reese T.S. Glutamate-induced transient modification of the postsynaptic density. Proc Natl Acad Sci U S A 2001, 98:10428-10432.
9. Dosemeci A., Vinade L., Winters C.A., Reese T.S., Tao-Cheng J.-H. Inhibition of phosphatase activity prolongs NMDA-induced modification of the postsynaptic density. J Neurocytol 2002, 31:605-612.
10. 2+/calmodulin-dependent protein kinase in rat brain. J Neurosci 1985, 5:3270-3277.
11. Lepicard E.M., Mizuno K., Antunes-Martins A., Von Hertzen L.S., Giese K.P. An endogenous inhibitor of calcium/calmodulin-dependent kinase II is up-regulated during consolidation of fear memory. Eur J Neurosci 2006, 23:3063-3070.
12. Lisman J., Schulman H., Cline H. The molecular basis of CaMKII function in synaptic and behavioral memory. Nat Rev Neurosci 2002, 3:175-190.
13. Lu Z., McLaren R.S., Winters C.A., Ralston E. Ribosome association contributes to restricting mRNAs to the cell body of hippocampal neurons. Mol Cell Neurosci 1998, 12:363-375.
14. Meyer T., Hanson P.I., Stryer L., Schulman H. Calmodulin trapping by calcium-calmodulin-dependent protein kinase. Science 1992, 256:1199-1202.
15. Mishra-Gorur K., Singer H.A., Castellot J.J. The S18 ribosomal protein is a putative substrate for Ca2+/calmodulin-activated protein kinase II. J Biol Chem 2002, 277:33537-33540.
16. Ostroff L.E., Fiala J.C., Allwardt B., Harris K.M. Polyribosomes redistribute from dendritic shafts into spines with enlarged synapses during LTP in developing rat hippocampal slices. Neuron 2002, 35:535-545.
17. Otmakhov N., Tao-Cheng J.H., Carpenter S., Asrican B., Dosemeci A., Reese T.S., Lisman J. Persistent accumulation of calcium/calmodulin-dependent protein kinase II in dendritic spines after induction of NMDA receptor-dependent chemical long-term potentiation. J Neurosci 2004, 24:9324-9331.
18. Patton B.L., Miller S.G., Kennedy M.B. Activation of type II calcium/calmodulin-dependent protein kinase by Ca2+/calmodulin is inhibited by autophosphorylation of threonine within the calmodulin-binding domain. J Biol Chem 1990, 265:11204-11212.
19. Radwańska K., Tudor-Jones A.A., Mizuno K., Pereira G.S., Lucchesi W., Alfano I., Łach A., Kaczmarek L., Knapp S., Giese K.P. Differential regulation of CaMKII inhibitor beta protein expression after exposure to a novel context and during contextual fear memory formation. Genes Brain Behav 2010, 9:648-657.
20. Sanhueza M., Fernandez-Villalobos G., Stein I.S., Kasumova G., Zhang P., Bayer K.U., Otmakhov N., Hell J.W., Lisman J. Role of the CaMKII/NMDA receptor complex in the maintenance of synaptic strength. J Neurosci 2011, 31:9170-9178.
21. Schuman E.M., Dynes J.L., Steward O. Synaptic regulation of translation of dendritic mRNAs. J Neurosci 2006, 26:7143-7146.
22. Tao-Cheng J.H. Activity-induced fine structural changes of synapses in mammalian central nervous system. Structure and function of the synapse 2012, Neuroscience-Net. V. Pickel, M. Segal (Eds.).
23. Tao-Cheng J.-H., Vinade L., Smith C., Winters C.A., Ward R., Brightman M.W., Reese T.S., Dosemeci A. Sustained elevation of calcium induces Ca(2+)/calmodulin-dependent protein kinase II clusters in hippocampal neurons. Neuroscience 2001, 106:69-78.
24. Tao-Cheng J.H., Gallant P.E., Brightman M.W., Dosemeci A., Reese T.S. Structural changes at synapses after delayed perfusion fixation in different regions of the mouse brain. J Comp Neurol 2007, 501:731-740.
25. Vest R.S., Davies K.D., O'Leary H., Port J.D., Bayer K.U. Dual mechanism of a natural CaMKII inhibitor. Mol Biol Cell 2007, 18:5024-5033.
26. Vest R.S., O'Leary H., Coultrap S.J., Kindy M.S., Bayer K.U. Effective post-insult neuroprotection by a novel Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) inhibitor. J Biol Chem 2010, 285:20675-20682.