Assessment of K-Ras mutant frequency and micronucleus incidence in the mouse duodenum following 90-days of exposure to Cr(VI) in drinking water

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 754, Issue 1-2, 2013, Pages 15-21

  O'Brien, Travis J ^a   Ding, Hao ^a   Suh, Mina ^b   Thompson, Chad M ^c   Parsons, Barbara L ^d   Harris, Mark A ^c   Winkelman, William A ^e   Wolf, Jeffrey C ^e   Hixon, J Gregory ^f   Schwartz, Arnold M ^a   Myers, Meagan B ^d   Haws, Laurie C ^f   Proctor, Deborah M ^b  

^a GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

^b ToxStrategies Inc   (United States)

^c ToxStrategies Inc   (United States)

^d NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^e EXPERIMENTAL PATHOLOGY LABORATORIES INC   (United States)

^f ToxStrategies Inc   (United States)

Author keywords

Cancer risk assessment; Hexavalent chromium; K Ras; Micronucleus; Mutation

Indexed keywords

CHROMIUM; DRINKING WATER; K RAS PROTEIN; SODIUM DICHROMATE DIHYDRATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER RISK; CELL PROLIFERATION; CODON; COLON CARCINOGENESIS; CONTROLLED STUDY; CYTOGENETICS; CYTOTOXICITY; DNA STRAND BREAKAGE; DUODENUM; FEMALE; GENE FREQUENCY; GENE MUTATION; GENOTOXICITY; IN VIVO STUDY; INCIDENCE; INTESTINE EPITHELIUM; LAMINA PROPRIA; LYMPHOCYTIC INFILTRATION; MICRONUCLEUS; MICROVILLUS; MITOSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; RISK ASSESSMENT;

ANIMALS; BASE SEQUENCE; CHROMIUM; CODON; DNA PRIMERS; DRINKING WATER; DUODENUM; FEMALE; GENES, RAS; MICE; MICRONUCLEUS TESTS; MUTATION; POLYMERASE CHAIN REACTION;

MUS;

EID: 84878478133     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2013.03.008     Document Type: Article

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