Preclinical dopaminergic dysfunction in rapid eye movement sleep behavior disorder

Sleep and Biological Rhythms

Volumn 11, Issue SUPPL.1, 2013, Pages 56-61

  Miyamoto, Tomoyuki ^a   Miyamoto, Masayuki ^a   Hirata, Koichi ^a  

^a DOKKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

Dementia with Lewy bodies; Parkinson's disease; PET; REM sleep behavior disorder; Substantia nigra; Transcranial ultrasound imaging

Indexed keywords

ARTICLE; CENTRAL NERVOUS SYSTEM DISEASE; DOPAMINERGIC DYSFUNCTION; DOPAMINERGIC NERVE CELL; DOPPLER ECHOGRAPHY; HUMAN; LEWY BODY; PARASOMNIA; PARKINSON DISEASE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SUBSTANTIA NIGRA; CORPUS STRIATUM; DIFFUSE LEWY BODY DISEASE; DISEASE PREDISPOSITION; ECHOGRAPHY; HIGH RISK POPULATION; IMAGE ANALYSIS; PROSPECTIVE STUDY; SHY DRAGER SYNDROME; TRANSCRANIAL SONOGRAPHY;

2BETA CARBOMETHOXY 3BETA (4 IODOPHENYL) N (3 FLUOROPROPYL)NORTROPANE I 123; 6 FLUORO META TYROSINE F 18; 6 FLUORODOPAMINE F 18; CATECHOL METHYLTRANSFERASE; DIHYDROTETRABENAZINE C 11; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

EID: 84878432969     PISSN: 14469235     EISSN: 14798425     Source Type: Journal    
DOI: 10.1111/j.1479-8425.2012.00554.x     Document Type: Article

References (20)

1. Schenck C, Mahowald M. REM sleep behavior disorder: clinical, developmental, and neuroscience perspectives 16years after its formal identification in SLEEP. Sleep 2002; 25: 120-38.
2. Schenck CH, Bundlie SR, Mahowald MW. Delayed emergence of a parkinsonian disorder in 38% of 29 older men initially diagnosed with idiopathic rapid eye movement sleep behavior disorder. Neurology 1996; 46: 388-92.
3. Iranzo A, Molinuevo JL, Santamaria J etal. Rapid-eye-movement sleep behaviour disorder as an early marker for a neurodegenerative disorder: a descriptive study. Lancet Neurol. 2006; 5: 572-7.
4. Postuma RB, Gagnon JF, Vendette M etal. Quantifying the risk of neurodegenerative disease in idiopathic REM sleep behavior disorder. Neurology 2009; 72: 1296-300.
5. Boeve BF. REM sleep behavior disorder: updated review of the core features, the REM sleep behavior disorder-neurodegenerative disease association, evolving, controversies, and future directions. Ann. N. Y. Acad. Sci. 2010; 1184: 15-54.
6. Albin RL, Koeppe RA, Chervin RD etal. Decreased striatal dopaminergic innervation in REM sleep behavior disorder. Neurology 2000; 55: 1410-2.
7. Eisensehr I, Linke R, Noachtar S, Schwarz J, Guildehaus FJ, Tatsch K. Reduced striatal dopamine transporters in idiopathic rapid eye movement sleep behaviour disorder. Brain 2000; 123: 1155-60.
8. Kim YK, Yoon IY, Kim JM etal. The implication of nigrostriatal degeneration in the pathogenesis of REM sleep behavior disorder. Eur. J. Neurol. 2010; 17: 487-92.
9. Brown WD, DeJesus OT, Pyzalski RW etal. Localization of trapping 6-[18F]fluoro-L-m-tyrosine, an aromatic l-amino acid decarboxylase tracer for PET. Synapse 1999; 34: 111-23.
10. Braskie MN, Wilcox CE, Landau SM etal. Relationship of striatal dopamine synthesis capacity to age and cognition. J. Neurosci. 2008; 28: 14320-8.
11. Aasari S, Fujimoto K, Miyauchi A etal. Subregional 6-[18F]fluoro-L-m-tyrosine uptake in the striatum in Parkinson's disease. BMC Neurol. 2011; 11: 35-41.
12. Berg D, Becker G, Zeiler B etal. Vulnerability of the nigrostriatal system as detected by transcranial ultrasound. Neurology 1999; 53: 1026-31.
13. Iwanami M, Miyamoto T, Miyamoto M, Hirata K, Takada E. Relevance of substantia nigra hyperechogenicity and reduced odor identification in idiopathic REM sleep behavior disorder. Sleep Med. 2010; 11: 361-5.
14. Stockner H, Iranzo A, Seppi K etal. Midbrain hyperechogenicity in idiopathic REM sleep behavior disorder. Mov. Disord. 2009; 24: 1906-9.
15. Miyamoto M, Miyamoto T, Iwanami M etal. Preclinical substantia nigra dysfunction in rapid eye movement sleep behaviour disorder. Sleep Med. 2012; 13: 102-6.
16. Berg D, Merz B, Reiners K, Naumann N, Becker G. Five-year follow-up study of hyperechogenicity of the substantia nigra in Parkinson's disease. Mov. Disord. 2005; 20: 383-5.
17. Miyamoto T, Orimo S, Miyamoto M etal. Follow-up PET studies in case of idiopathic REM sleep behavior disorder. Sleep Med. 2010; 11: 100-1.
18. Nurmi E, Bergman J, Eskola O etal. Progression of dopaminergic hypofunction in striatal subregions in Parkinson's disease using [18F]CFT PET. Synapse 2003; 48: 109-15.
19. Iranzo A, Lomeña F, Stockner H etal. Decreased striatal dopamine transporter uptake and substantia nigra hyperechogenicity as risk markers of synucleinopathy in patients with idiopathic rapid-eye-movement sleep behaviour disorder: a prospective study [corrected]. Lancet Neurol. 2010; 9: 1070-7.
20. Iranzo A, Valldeoriola F, Lomeña F etal. Serial dopamine transporter imaging of nigrostriatal function in patients with idiopathic rapid-eye-movement sleep behaviour disorder: a prospective study. Lancet Neurol. 2011; 10: 797-805.