메뉴 건너뛰기




Volumn 34, Issue 2, 1999, Pages 111-123

Localization of trapping of 6-[18F]fluoro-L-m-tyrosine, an aromatic L- amino acid decarboxylase tracer for PET

Author keywords

6 FMT; Dopamine; FluoroDOPA; Monoamine neurotransmitter; Positron emission tomography

Indexed keywords

AMINO ACID DECARBOXYLASE; CATECHOLAMINE; DOPAMINE; FLUORINE 18; FLUORODOPA F 18; META TYROSINE; NEUROTRANSMITTER; NORADRENALIN; SEROTONIN; TRACER; UNCLASSIFIED DRUG;

EID: 0032887819     PISSN: 08874476     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2396(199911)34:2<111::AID-SYN4>3.0.CO;2-0     Document Type: Article
Times cited : (23)

References (66)
  • 1
    • 0028568077 scopus 로고
    • Immunohistochemical evidence that central serotonin neurons produce dopamine from exogenous L-DOPA in the rat, with reference to the involvement of aromatic L-amino acid decarboxylase
    • Arai R, Karasawa N, Geffard M, Nagatsu T, Nagatsu I. 1994. Immunohistochemical evidence that central serotonin neurons produce dopamine from exogenous L-DOPA in the rat, with reference to the involvement of aromatic L-amino acid decarboxylase. Brain Res 667:295-299.
    • (1994) Brain Res , vol.667 , pp. 295-299
    • Arai, R.1    Karasawa, N.2    Geffard, M.3    Nagatsu, T.4    Nagatsu, I.5
  • 3
    • 0001480322 scopus 로고
    • The distribution of serotonin 5-hydroxytryptophan decarboxylase, and monoamine oxidase in brain
    • Bogdanski D, Weissbach H, Udenfriend S. 1957. The distribution of serotonin 5-hydroxytryptophan decarboxylase, and monoamine oxidase in brain. J Neurochem 1:272-278.
    • (1957) J Neurochem , vol.1 , pp. 272-278
    • Bogdanski, D.1    Weissbach, H.2    Udenfriend, S.3
  • 4
    • 0022931450 scopus 로고
    • 18F]-6-fluoroDOPA during positron emission tomography: Elimination and metabolism in carbidopa treated subjects
    • 18F]-6-fluoroDOPA during positron emission tomography: elimination and metabolism in carbidopa treated subjects. Life Sci 39:2243-2252.
    • (1986) Life Sci , vol.39 , pp. 2243-2252
    • Boyes, B.E.1    Cumming, P.2    Martin, W.R.3    McGeer, E.G.4
  • 5
    • 0025185168 scopus 로고
    • The relationship between locomotor disability, autonomic dysfunction, and the integrity of the striatal dopaminergic system in patients with multiple system atrophy, pure autonomic failure, and Parkinson's disease, studied with PET
    • Brooks DJ, Salmon EP, Mathias CJ, Quinn N, Leenders KL, Bannister R, Marsden CD, Frackowiak RS. 1990. The relationship between locomotor disability, autonomic dysfunction, and the integrity of the striatal dopaminergic system in patients with multiple system atrophy, pure autonomic failure, and Parkinson's disease, studied with PET. Brain 113:1539-1552.
    • (1990) Brain , vol.113 , pp. 1539-1552
    • Brooks, D.J.1    Salmon, E.P.2    Mathias, C.J.3    Quinn, N.4    Leenders, K.L.5    Bannister, R.6    Marsden, C.D.7    Frackowiak, R.S.8
  • 6
    • 0017339158 scopus 로고
    • Catecholamines in neocortex of rhesus monkeys: Regional distribution and ontogenetic development
    • Brown RM, Goldman PS. 1977. Catecholamines in neocortex of rhesus monkeys: regional distribution and ontogenetic development. Brain Res 124:576-580.
    • (1977) Brain Res , vol.124 , pp. 576-580
    • Brown, R.M.1    Goldman, P.S.2
  • 7
    • 0018384739 scopus 로고
    • Regional distribution of monoamines in the cerebral cortex and subcortical structures of the rhesus monkey: Concentrations and in vivo synthesis rates
    • Brown RM, Crane AM, Goldman PS. 1979. Regional distribution of monoamines in the cerebral cortex and subcortical structures of the rhesus monkey: concentrations and in vivo synthesis rates. Brain Res 168:133-150.
    • (1979) Brain Res , vol.168 , pp. 133-150
    • Brown, R.M.1    Crane, A.M.2    Goldman, P.S.3
  • 8
    • 0026610707 scopus 로고
    • 18F]-L-6-fluoroDOPA and its metabolites in blood plasma is essential for accurate positron emission tomography studies
    • 18F]-L-6-fluoroDOPA and its metabolites in blood plasma is essential for accurate positron emission tomography studies. Life Sci 50:309-318.
    • (1992) Life Sci , vol.50 , pp. 309-318
    • Chan, G.L.-Y.1    Hewitt, K.A.2    Pate, B.D.3    Schofield, P.4    Adam, M.J.5    Ruth, T.J.6
  • 9
    • 0005207410 scopus 로고
    • Some aspects of the biochemistry of the substantia nigra of the rhesus monkey
    • Barbeau A, Brunette JR, editors Amsterdam: Excerpta Medica
    • Côté L Fahn, S. 1968. Some aspects of the biochemistry of the substantia nigra of the rhesus monkey. In: Barbeau A, Brunette JR, editors. Proceedings of the 2nd International Congress of Neurogenetics and Neuro-ophthalmology. Amsterdam: Excerpta Medica. p 311-317.
    • (1968) Proceedings of the 2nd International Congress of Neurogenetics and Neuro-ophthalmology , pp. 311-317
    • Côté, L.1    Fahn, S.2
  • 11
    • 0018696215 scopus 로고
    • Turnover of free and conjugated (sulphonyloxy) dihydroxyphenylacetic acid and homovanillic acid in rat striatum
    • Dedek J, Baumes R, Tien-Duc N, Gomeni R, Korf J. 1979. Turnover of free and conjugated (sulphonyloxy) dihydroxyphenylacetic acid and homovanillic acid in rat striatum. J Neurochem 33:687-695.
    • (1979) J Neurochem , vol.33 , pp. 687-695
    • Dedek, J.1    Baumes, R.2    Tien-Duc, N.3    Gomeni, R.4    Korf, J.5
  • 13
    • 0024286852 scopus 로고
    • Radiobrominated m-tyrosine analog as potential CNS L-DOPA PET tracer
    • DeJesus OT, Mukherjee J. 1988. Radiobrominated m-tyrosine analog as potential CNS L-DOPA PET tracer. Biochem Biophys Res Commun 150:1027-1031.
    • (1988) Biochem Biophys Res Commun , vol.150 , pp. 1027-1031
    • DeJesus, O.T.1    Mukherjee, J.2
  • 17
    • 0000940250 scopus 로고
    • Synthesis of brominated and fluorinated ortho-tyrosine analogs as potential DOPA decarboxylase tracers
    • DeJesus OT, Murali D, Nickles RJ. 1995. Synthesis of brominated and fluorinated ortho-tyrosine analogs as potential DOPA decarboxylase tracers. J Label Comp Radiopharm 37:147.
    • (1995) J Label Comp Radiopharm , vol.37 , pp. 147
    • DeJesus, O.T.1    Murali, D.2    Nickles, R.J.3
  • 18
    • 0030899568 scopus 로고    scopus 로고
    • Evaluation of fluorinated m-tyrosine analogs as PET imaging agents of dopamine nerve terminals: Comparison with 6-fluoroDOPA
    • DeJesus OT, Endres CJ, Shelton SE, Nickles RJ, Holden JE. 1997. Evaluation of fluorinated m-tyrosine analogs as PET imaging agents of dopamine nerve terminals: comparison with 6-fluoroDOPA. J Nucl Med 38:630-636.
    • (1997) J Nucl Med , vol.38 , pp. 630-636
    • DeJesus, O.T.1    Endres, C.J.2    Shelton, S.E.3    Nickles, R.J.4    Holden, J.E.5
  • 19
    • 0025989174 scopus 로고
    • In vivo pharmacokinetics of levodopa and 3-O-methyldopa in muscle. Amicrodialysis study
    • Deleu D, Sarre S, Ebinger G, Michotte Y. 1991. In vivo pharmacokinetics of levodopa and 3-O-methyldopa in muscle. Amicrodialysis study. Naunyn Schmiedebergs Arch Pharmacol 344:514-519.
    • (1991) Naunyn Schmiedebergs Arch Pharmacol , vol.344 , pp. 514-519
    • Deleu, D.1    Sarre, S.2    Ebinger, G.3    Michotte, Y.4
  • 23
    • 0026654170 scopus 로고
    • Delayed L-phenylalanine infusion allows for simultaneous kinetic analysis and improved evaluation of specific-to-nonspecific fluorine-18-DOPA uptake in brain
    • Doudet DJ, McLellan CA, Aigner TG, Wyatt RJ, Cohen RM. 1992. Delayed L-phenylalanine infusion allows for simultaneous kinetic analysis and improved evaluation of specific-to-nonspecific fluorine-18-DOPA uptake in brain. J Nucl Med 33:1383-1389.
    • (1992) J Nucl Med , vol.33 , pp. 1383-1389
    • Doudet, D.J.1    McLellan, C.A.2    Aigner, T.G.3    Wyatt, R.J.4    Cohen, R.M.5
  • 24
    • 0031005861 scopus 로고    scopus 로고
    • Effects of catechol-O-methyltransferase inhibition on the rates of uptake and reversibility of 6-fluoro-L-Dopa trapping in MPTP-induced parkinsonism in monkeys
    • Doudet DJ, Chan GLY, Holden JE, Morrison KS, Wyatt RJ, Ruth TJ. 1997. Effects of catechol-O-methyltransferase inhibition on the rates of uptake and reversibility of 6-fluoro-L-Dopa trapping in MPTP-induced parkinsonism in monkeys. Neuropharmacology 36: 363-371.
    • (1997) Neuropharmacology , vol.36 , pp. 363-371
    • Doudet, D.J.1    Chan, G.L.Y.2    Holden, J.E.3    Morrison, K.S.4    Wyatt, R.J.5    Ruth, T.J.6
  • 25
    • 0026609354 scopus 로고
    • Positron emission tomography studies in parkinsonism
    • Eidelberg D. 1992. Positron emission tomography studies in parkinsonism. Neurol Clinics 10:421-433.
    • (1992) Neurol Clinics , vol.10 , pp. 421-433
    • Eidelberg, D.1
  • 31
    • 0026063687 scopus 로고
    • Do the metabolites of 6-[F-18]fluoro-L-DOPA and of [F-18]fluoro-meta-L-tyrosine contribute to the F-18 accumulation in the human brain?
    • Firnau G, Chirakal R, Nahmias C, Garnett ES. 1991. Do the metabolites of 6-[F-18]fluoro-L-DOPA and of [F-18]fluoro-meta-L-tyrosine contribute to the F-18 accumulation in the human brain? J Label Comp Radiopharm 30:293-294.
    • (1991) J Label Comp Radiopharm , vol.30 , pp. 293-294
    • Firnau, G.1    Chirakal, R.2    Nahmias, C.3    Garnett, E.S.4
  • 32
    • 0021047386 scopus 로고
    • Striatal dopamine metabolism in living monkeys examined by positron emission tomography
    • Garnett S, Firnau G, Nahmias C, Chirakal R. 1983. Striatal dopamine metabolism in living monkeys examined by positron emission tomography. Brain Res 280:169-171.
    • (1983) Brain Res , vol.280 , pp. 169-171
    • Garnett, S.1    Firnau, G.2    Nahmias, C.3    Chirakal, R.4
  • 33
    • 0016829492 scopus 로고
    • Catechol-O-methyl transferase: Pharmacological aspects and physiological role
    • Guldberg HC, Marsden CA. 1975. Catechol-O-methyl transferase: pharmacological aspects and physiological role. Pharmacol Rev 27:135-206.
    • (1975) Pharmacol Rev , vol.27 , pp. 135-206
    • Guldberg, H.C.1    Marsden, C.A.2
  • 34
    • 0005505447 scopus 로고
    • Observations on the substrate specificity of dopa decarboxylase from ox adrenal medulla, human phaeochromocytoma, and human argentaffinoma
    • Hagen P. 1962. Observations on the substrate specificity of dopa decarboxylase from ox adrenal medulla, human phaeochromocytoma, and human argentaffinoma. Br J Pharmacol 18:175-182.
    • (1962) Br J Pharmacol , vol.18 , pp. 175-182
    • Hagen, P.1
  • 35
    • 0027485236 scopus 로고
    • The transport of L-6-fluorodopa and its metabolites from blood to cerebrospinal fluid and brain
    • Hammerstad JP, Pate BD, Hewitt KA, Chan GL-Y, Ruth TJ, Calne DB. 1993. The transport of L-6-fluorodopa and its metabolites from blood to cerebrospinal fluid and brain. Ann Neurol 34:603-608.
    • (1993) Ann Neurol , vol.34 , pp. 603-608
    • Hammerstad, J.P.1    Pate, B.D.2    Hewitt, K.A.3    Chan, G.L.-Y.4    Ruth, T.J.5    Calne, D.B.6
  • 36
    • 0018746319 scopus 로고
    • Studies on the enzymatic blood-brain barrier: Quantitative measurements of DOPA decarboxylase in the wall of microvessels as related to the parenchyma in various CNS regions
    • Hardebo JE, Falck B, Owman C, Rosengren E. 1979. Studies on the enzymatic blood-brain barrier: quantitative measurements of DOPA decarboxylase in the wall of microvessels as related to the parenchyma in various CNS regions. Acta Physiol Scand 105:453-460.
    • (1979) Acta Physiol Scand , vol.105 , pp. 453-460
    • Hardebo, J.E.1    Falck, B.2    Owman, C.3    Rosengren, E.4
  • 39
    • 0030816179 scopus 로고    scopus 로고
    • Physiologic modeling of PET data: Quantitative conflict and challenge
    • Ichise M, Ballinger JR. 1997. Physiologic modeling of PET data: quantitative conflict and challenge. J Nucl Med 38:1266-1267.
    • (1997) J Nucl Med , vol.38 , pp. 1266-1267
    • Ichise, M.1    Ballinger, J.R.2
  • 40
    • 0345690397 scopus 로고    scopus 로고
    • Fluorodopa positron emission tomography with an inhibitor of catechol-O-methyltransferase
    • Myers R, Cunningham V, Bailey D, Jones T, editors San Diego: Academic Press
    • Ishikawa T, Dhawan V, Patlak C et al. 1996. Fluorodopa positron emission tomography with an inhibitor of catechol-O-methyltransferase. In: Myers R, Cunningham V, Bailey D, Jones T, editors. Quantification of Brain Function Using PET. San Diego: Academic Press. p 232-236.
    • (1996) Quantification of Brain Function Using PET , pp. 232-236
    • Ishikawa, T.1    Dhawan, V.2    Patlak, C.3
  • 44
    • 0027375492 scopus 로고
    • Decarboxylation of L-dopa by cultured mouse astrocytes
    • Juorio AV, Li X-M Walz, W Paterson IA. 1993. Decarboxylation of L-dopa by cultured mouse astrocytes. Brain Res 626:306-309.
    • (1993) Brain Res , vol.626 , pp. 306-309
    • Juorio, A.V.1    Li, X.-M.2    Walz, W.3    Paterson, I.A.4
  • 45
    • 0023724604 scopus 로고
    • Costorage of serotonin binding protein with serotonin in the rat CNS
    • Kirchgessner AL, Gershon MD, Liu KP, Tamir H. 1988. Costorage of serotonin binding protein with serotonin in the rat CNS. J Neurosci 8:3879-3890.
    • (1988) J Neurosci , vol.8 , pp. 3879-3890
    • Kirchgessner, A.L.1    Gershon, M.D.2    Liu, K.P.3    Tamir, H.4
  • 46
    • 84982333824 scopus 로고
    • Microanalytical procedures for fluprometric assay of brain DOPA-5HTP decarboxylase, norepinephrine and serotonin, and a detailed mapping of decarboxylase activity in brain
    • Kuntzman R, Shore P, Bogdanski D, Brodie BB. 1961. Microanalytical procedures for fluprometric assay of brain DOPA-5HTP decarboxylase, norepinephrine and serotonin, and a detailed mapping of decarboxylase activity in brain. J Neurochem 6:226-232.
    • (1961) J Neurochem , vol.6 , pp. 226-232
    • Kuntzman, R.1    Shore, P.2    Bogdanski, D.3    Brodie, B.B.4
  • 48
    • 0015353353 scopus 로고
    • Occurrence and distribution of aromatic L-amino acid (L-DOPA) decarboxylase in the human brain
    • Lloyd KG, Hornykiewicz O. 1972. Occurrence and distribution of aromatic L-amino acid (L-DOPA) decarboxylase in the human brain. J Neurochem 19:1549-1959.
    • (1972) J Neurochem , vol.19 , pp. 1549-1959
    • Lloyd, K.G.1    Hornykiewicz, O.2
  • 49
    • 0019160120 scopus 로고
    • Nonaminergic striatal neurons convert exogenous L-dopa to dopamine in parkinsonism
    • Melamed E, Hefti F, Wurtman RJ. 1980. Nonaminergic striatal neurons convert exogenous L-dopa to dopamine in parkinsonism. Ann Neurol 8:558-563.
    • (1980) Ann Neurol , vol.8 , pp. 558-563
    • Melamed, E.1    Hefti, F.2    Wurtman, R.J.3
  • 52
    • 0026902794 scopus 로고
    • 18F]fluoro-β-fluoromethylene-m-tyrosine analogs, potential PET agents for presynaptic dopamine terminals: Synthesis and spectroscopic characterization
    • 18F]fluoro-β-fluoromethylene-m-tyrosine analogs, potential PET agents for presynaptic dopamine terminals: synthesis and spectroscopic characterization. Int J Radiat Appl Instr Part A, Appl Radiat Isot 43:969-977.
    • (1992) Int J Radiat Appl Instr Part A, Appl Radiat Isot , vol.43 , pp. 969-977
    • Murali, D.1    DeJesus, O.T.2    Sunderland, J.J.3    Nickles, R.J.4
  • 55
    • 0022389649 scopus 로고
    • Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data. Generalizations
    • Patlak CS, Blasberg RG. 1985. Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data. Generalizations. J Cereb Blood Flow Metab 5:584-590.
    • (1985) J Cereb Blood Flow Metab , vol.5 , pp. 584-590
    • Patlak, C.S.1    Blasberg, R.G.2
  • 57
    • 0011214758 scopus 로고
    • Reserpine, monoamine oxidase inhibitors, and distribution of biogenic amines in monkey brain
    • Pscheidt G, Himwich HE. 1963. Reserpine, monoamine oxidase inhibitors, and distribution of biogenic amines in monkey brain. Biochem Pharmacol 12:65-71.
    • (1963) Biochem Pharmacol , vol.12 , pp. 65-71
    • Pscheidt, G.1    Himwich, H.E.2
  • 58
    • 0019430470 scopus 로고
    • Aromatic L-amino acid decarboxylase activity in central and peripheral tissues and serum of rats with L-DOPA and L-5-hydroxytryptophan as substrates
    • Rahman MK, Nagatsu T, Kato T. 1981. Aromatic L-amino acid decarboxylase activity in central and peripheral tissues and serum of rats with L-DOPA and L-5-hydroxytryptophan as substrates. Biochem Pharmacol 30:645-649.
    • (1981) Biochem Pharmacol , vol.30 , pp. 645-649
    • Rahman, M.K.1    Nagatsu, T.2    Kato, T.3
  • 59
    • 0015313191 scopus 로고
    • Levels and distribution of central nervous system amines in normal and morphine-dependent monkeys
    • Segal M, Deneau GA, Seevers MH. 1972. Levels and distribution of central nervous system amines in normal and morphine-dependent monkeys. Neuropharmacology 11:211-222.
    • (1972) Neuropharmacology , vol.11 , pp. 211-222
    • Segal, M.1    Deneau, G.A.2    Seevers, M.H.3
  • 60
    • 0018086726 scopus 로고
    • Substrate specificity and other properties of DOPA decarboxylase from guinea pig kidneys
    • Srinivasan K, Awapara J. 1978. Substrate specificity and other properties of DOPA decarboxylase from guinea pig kidneys. Biochim Biophys Acta 526:597-604.
    • (1978) Biochim Biophys Acta , vol.526 , pp. 597-604
    • Srinivasan, K.1    Awapara, J.2
  • 62
    • 0020868052 scopus 로고
    • Serotonin-binding protein: Function in synaptic vesicles
    • Tamir H. 1983. Serotonin-binding protein: function in synaptic vesicles. Trans NY Acad Sci 41:237-242.
    • (1983) Trans NY Acad Sci , vol.41 , pp. 237-242
    • Tamir, H.1
  • 65
    • 0029864250 scopus 로고    scopus 로고
    • Modeling of fluorine-18-6-fluoro-L-Dopa in humans
    • Wahl L, Nahmias C. 1996. Modeling of fluorine-18-6-fluoro-L-Dopa in humans. J Nucl Med 37:432-437.
    • (1996) J Nucl Med , vol.37 , pp. 432-437
    • Wahl, L.1    Nahmias, C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.