Monoclonal antibodies to 65kDa glutamate decarboxylase induce epitope specific effects on motor and cognitive functions in rats

Orphanet Journal of Rare Diseases

Volumn 8, Issue 1, 2013, Pages

  Hampe, Christiane S ^a   Petrosini, Laura ^b,e   De Bartolo, Paola ^b,e   Caporali, Paola ^g   Cutuli, Debora ^b,e   Laricchiuta, Daniela ^g   Foti, Francesca ^c,f   Radtke, Jared R ^a   Vidova, Veronika ^a   Honnorat, Jérôme ^c   Manto, Mario ^d  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^c UNIVERSITÉ DE LYON   (France)

^d UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^e SAPIENZA UNIVERSITY OF ROME   (Italy)

^f SAPIENZA UNIVERSITY OF ROME   (Italy)

^g NONE

Author keywords

Evaluation; Glutamate decarboxylase; Monoclonal antibodies; Morris Water Maze; Neurological

Indexed keywords

EPITOPE; GLUTAMATE DECARBOXYLASE 65 ANTIBODY; MONOCLONAL ANTIBODY; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRIGHT FIELD MICROSCOPY; CEREBELLUM NUCLEUS; COGNITION; CONTROLLED STUDY; DOSE RESPONSE; FLOW CYTOMETRY; INTERNALIZATION; LOCOMOTION; MALE; MAZE TEST; MOTOR DYSFUNCTION; MOTOR PERFORMANCE; NEUROLOGIC EXAMINATION; NONHUMAN; PROTEIN EXPRESSION; RAT;

ANIMALS; ANTIBODIES, MONOCLONAL; AUTOANTIBODIES; BEHAVIOR, ANIMAL; CELL LINE; COGNITION; EPITOPES; GLUTAMATE DECARBOXYLASE; MALE; MOTOR SKILLS; NEURONS; PROTEIN ISOFORMS; RATS; RATS, WISTAR; STIFF-PERSON SYNDROME;

EID: 84878427393     PISSN: None     EISSN: 17501172     Source Type: Journal    
DOI: 10.1186/1750-1172-8-82     Document Type: Article

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