Glutathione S-transferase polymorphisms, asthma susceptibility and confounding variables: A meta-analysis

Molecular Biology Reports

Volumn 40, Issue 4, 2013, Pages 3299-3313

  Piacentini, Sara ^a   Polimanti, Renato ^a   Simonelli, Ilaria ^b,c   Donno, Silvia ^b   Pasqualetti, Patrizio ^b,c   Manfellotto, Dario ^b   Fuciarelli, Maria ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b FATEBENEFRATELLI HOSPITAL   (Italy)

^c IRCCS SAN RAFFAELE PISANA   (Italy)

Author keywords

Asthmatic disease; Genetic predisposition to disease; GSTM1; GSTP1; GSTT1; Oxidative stress

Indexed keywords

GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE P1; GLUTATHIONE TRANSFERASE T1;

AGE; ARTICLE; ASTHMA; ETHNICITY; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENOTYPE; GLUTATHIONE S TRANSFERASE GENE; HUMAN; SYSTEMATIC REVIEW; URBANIZATION;

ASTHMA; CONFOUNDING FACTORS (EPIDEMIOLOGY); GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; GLUTATHIONE S-TRANSFERASE PI; GLUTATHIONE TRANSFERASE; HUMANS; OXIDATIVE STRESS; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS;

EID: 84878414628     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-012-2405-2     Document Type: Article

References (63)

1. Meng J, Rosenwasser LJ (2010) Unraveling the genetic basis of asthma and allergic diseases. Allergy Asthma Immunol Res 2:215-227
2. Minelli C, Granell R, Newson R, Rose-Zerilli MJ, Torrent M, Ring SM et al (2010) Glutathione-S-transferase genes and asthma phenotypes: a human genome epidemiology (huge) systematic review and meta-analysis including unpublished data. Int J Epidemiol 39:539-562
3. Nadeem A, Masood A, Siddiqui N (2008) Oxidant-antioxidant imbalance in asthma: scientific evidence, epidemiological data and possible therapeutic options. Ther Adv Respir Dis 2:215-235
4. Economopoulos KP, Sergentanis TN (2010) GSTM1, GSTT1, GSTP1, GSTA1 and colorectal cancer risk: a comprehensive meta-analysis. Eur J Cancer 46:1617-1631
5. Piacentini S, Polimanti R, Porreca F, Martínez-Labarga C, De Stefano GF, Fuciarelli M (2011) GSTT1 and GSTM1 gene polymorphisms in European and African populations. Mol Biol Rep 38:1225-1230
6. Polimanti R, Piacentini S, Porreca F, Fuciarelli M (2010) Glutathione S-transferase ω class (GSTO) polymorphisms in a sample from Rome (Central Italy). Ann Hum Biol 37:585-592
7. Piacentini S, Polimanti R, Squitti R, Ventriglia M, Cassetta E, Vernieri F et al (2012) GSTM1 null genotype as risk factor for late-onset Alzheimer's disease in Italian patients. J Neurol Sci 317:137-140
8. Polimanti R, Piacentini S, Lazzarin N, Re MA, Manfellotto D, Fuciarelli M (2011) Glutathione S-transferase variants as risk factor for essential hypertension in Italian patients. Mol Cell Biochem 357:227-233
9. Polimanti R, Piacentini S, Lazzarin N, Vaquero E, Re MA, Manfellotto D et al (2012) Glutathione S-transferase genes and the risk of recurrent miscarriage in Italian women. Fertil Steril 98:396-400
10. Frova C (2006) Glutathione transferases in the genomics era: new insights and perspectives. Biomol Eng 23:149-169
11. Polimanti R, Piacentini S, Moscatelli B, Pellicciotti L, Manfellotto D, Fuciarelli M (2010) GSTA1, GSTO1 and GSTO2 gene polymorphisms in Italian asthma patients. Clin Exp Pharmacol Physiol 37:870-872
12. Piacentini S, Polimanti R, Moscatelli B, Re MA, Fuciarelli R, Manfellotto D et al (2010) Glutathione S-transferase gene polymorphisms and air pollution as interactive risk factors for asthma in a multicentre Italian field study: a preliminary study. Ann Hum Biol 37:427-439
13. Fryer AA, Bianco A, Hepple M, Jones PW, Strange RC, Spiteri MA (2000) Polymorphism at the glutathione S-transferase GSTP1 locus. A new marker for bronchial hyperresponsiveness and asthma. Am J Respir Crit Care Med 161:1437-1442
14. Abdel-Alim S, El-Masry MM, Aziz M, El-Bassiony SO, Aly AA (2007) Association of glutathione-S-transferase P1 genotypes with susceptibility to bronchial asthma in children. Arch Med Sci 3:200-207
15. Hanene C, Jihene L, Jamel A, Kamel H, Agnes H (2007) Association of GST genes polymorphisms with asthma in Tunisian children. Mediators Inflamm 2007:19564
16. Tamer L, Calikoglu M, Ates NA, Yildirim H, Ercan B, Saritas E et al (2004) Glutathione-S-transferase gene polymorphisms (GSTT1, GSTM1, GSTP1) as increased risk factors for asthma. Respirology 9:493-498
17. Romieu I, Ramirez-Aguilar M, Sienra-Monge JJ (2006) GSTM1 and GSTP1 and respiratory health in asthmatic children exposed to ozone. Eur Respir J 28:953-959
18. Safranova OG, Vavilin VA, Lyapunova AA, Makarova SI, Lyakhovich VV, Kaznacheeva LF et al (2003) Relationship between glutathione S-transferase P1 polymorphism and bronchial asthma and atopic dermatitis. Bull Exp Biol Med 136:73-75
19. Muñoz B, Magaña JJ, Romero-Toledo I, Juárez- Pérez E, López-Moya A, Leiva-Garcia N et al (2012) The relationship among IL-13, GSTP1, and CYP1A1 polymorphisms and environmental tobacco smoke in a population of children with asthma in Northern Mexico. Environ Toxicol Pharmacol 33:226-232
20. Saadat M, Ansari-Lari M (2007) Genetic polymorphism of glutathione S-transferase T1, M1 and asthma, a meta-analysis of literature. Pak J Biol Sci 10:4183-4189
21. Higgins JP, Thompson SG (2002) Quantifying heterogeneity in a meta-analysis. Stat Med 21:1539-1548
22. Saadat M, Saadat I, Saboori Z, Emad A (2004) Combination of CC16, GSTM1, and GSTT1 genetic polymorphisms is associated with asthma. J Allergy Clin Immunol 113:996-998
23. Lima CSP, Néri IA, Lourenço GJ, Faria ICJ, Ribeiro JD, Bertuzzo CS (2010) Glutathione S-transferase mu 1 (GSTM1) and theta 1 (GSTT1) genetic polymorphisms and atopic asthma in children from Southeastern Brazil. Gen Mol Biol 33:438-441
24. Freidin MB, Bragina EY, Ogorodova LM, Puzyrev VP (2002) Polymorphism of the glutathione S-transferase genes (GSTT1, GSTM1) in West Siberian patients with atopic bronchial asthma. Mol Biol 36:493-496
25. Plutecka H, Sanak M, Diezdzina S, Mastalerz L, Szczeklik A (2006) Reactive oxygen species metabolism and allergy. Allergy Clin Immunol Int 18:158-164
26. Ioannidis JP (2008) Interpretation of tests of heterogeneity and bias in meta-analysis. J Eval Clin Pract 14:951-957
27. Kabesch M (2006) Gene by environment interactions and the development of asthma and allergy. Toxicol Lett 162:43-48
28. Eder W, Ege MJ, von Mutius E (2006) The asthma epidemic. New Engl J Med 355:2226-2235
29. Schell LM, Burnitz KK, Lathrop PW (2010) Pollution and human biology. Ann Hum Biol 37:347-366
30. Polimanti R, Piacentini S, Manfellotto D, Fuciarelli M (2012) Human genetic variation of cytochrome P450 superfamily: analysis of functional diversity in worldwide populations. Pharmacogenomics 13:1951-1960
31. Chung HW, Ahn TH, Kim SY, Kim TY, Pack D (2002) Polymorphisms of GSTM1, GSTT1, GSTP1, NATII and CYP1A1 and the susceptibility to asthma. Korean J Gen 24:259-266
32. Ivaschenko TE, Sideleva OG, Baranov VS (2002) Glutathione-S-transferase μ and theta gene polymorphisms as new risk factors of atopic bronchial asthma. J Mol Med 80:39-43
33. Vavilin VA, Makaro SI, Lyakhovich VV, Gavalov SM (2002) Polymorphic genes of xenobiotic-metabolizing enzymes associated with predisposition to bronchial asthma in hereditarily burdened and non-burdened children. Russian J Gen 38:439-445
34. Aynacioglu AS, Nacak M, Filiz A, Ekinci E, Roots I (2003) Protective role of glutathione S-transferase P1 (GSTP1) Val105Val genotype in patients with bronchial asthma. Br J Clin Pharmacol 57:213-217
35. Kabesch M, Hoefler C, Carr D, Leupold W, Weiland SK, Von Mutius E (2004) Glutathione S transferase deficiency and passive smoking increase childhood asthma. Thorax 59:569-573
36. Ebrahimi M, Podolskaya SV, Gorovenko NG (2004) Genetic polymorphisms of glutathione S-transferase mu1 (GSTM1) and theta1 (GSTT1) and bronchial asthma susceptibility in Ukrainian population. Iran J Biotechnol 2:230-235
37. Zhang YQ, Sun BY, Dai JJ, Wu SS, Zhang AP, Zhao CF et al (2004) Studies on the genetic diathesis of asthma bronchial. Yi Chuan 26:147-150
38. Lee Y, Hsiue T, Lee Y, Lin Y, Guo YL (2005) The association between glutathione S-transferase P1, M1 polymorphisms and asthma in Taiwanese schoolchildren. Chest 128:1156-1162
39. Nickel R, Haider A, Sengler C, Lau S, Niggemann B, Deichmann KA et al (2005) Association study of glutathione S-transferase P1 (GSTP1) with asthma and bronchial hyper-responsiveness in two German pediatric populations. Pediatr Allergy Immunol 16:539-541
40. Oh J, Kim S, Suh C, Nahm D, Park H, Lee Y et al (2005) Lack of association of glutathione S-transferase P1 Ile105Val polymorphism with aspirin-intolerant asthma. J Korean Med 20:232-236
41. Arbag H, Cora T, Acar H, Ozturk Sari F, Ulusoy B (2006) Lack of association between the glutathione-S-transferase genes (GSTT1 and GSTM1) and nasal polyposis. Rhinology 44:14-18
42. Ercan H, Birben E, Dizdar EA, Keskin O, Karaasian C, Ozge US et al (2006) Oxidative stress and genetic and epidemiologic determinants of oxidant injury in childhood asthma. J All Clin Immunol 118:97-104
43. Holla LI, Stejskalova A, Vasku A (2006) Polymorphisms of the GSTM1 and GSTT1 genes in patients with allergic diseases in the Czech population. Allergy 61:265-267
44. Imboden M, Rochat T, Brutsche MH, Schindler C, Downs S, Gerbase MW et al (2007) Glutathione-S transferase genotype increases risk of progression from bronchial hyperresponsiveness to asthma in adults. Thorax 63:322-328
45. Kamada F, Mashimo Y, Inoue H, Shao C, Hirota T, Doi S et al (2007) The GSTP1 gene is a susceptibility childhood asthma and the GSTM1 gene is a modifier of the GSTP1 gene. Int Arch Allergy Immunol 144:275-286
46. Mak JCW, Ho SP, Leung HCM, Cheung AHK, Law BKW, Sow LKY et al (2007) Relationship between glutathione S-transferase gene polymorphisms and enzyme activity in Hong Kong Chinese asthmatics. Clin Exp All 37:1150-1157
47. Salam MT, Lin P, Avol EL, Gauderman WJ, Gilliland FD (2007) Microsomal epoxide hydrolase, glutathione S-transferase P1, traffic and childhood asthma. Thorax 62:1050-1057
48. Babusikova E, Jesenak M, Kirschnerova R, Banovcin P, Dobrota D (2009) Association of oxidative stress and GST-T1 gene with childhood bronchial asthma. J Physiol Pharmacol 60:27-30
49. Castro-Giner F, Künzli N, Jacquemin B, Forsberg B, de Cid R, Sunyer J et al (2009) Traffic-related air pollution, oxidative stress genes, and asthma (ECHRS). Environ Health Perspect 117:1919-1924
50. Federova YY, Gra OA, Karunas AS, Khuzina AK, Ramazanova NN, Yuldasheva AA et al (2009) Association of polymorphisms of xenobiotic metabolism genes with childhood atopic diseases in Russian patients from Bashkortostan. Mol Biol 43:961-967
51. Gravina P, Angelini F, Chianca M, Valentini A, Bellincampi L, Iannini R et al (2009) GSTP1*B allele increases the risk for asthma in children. Clin Chem Lab Med 47:1451-1453
52. Li Y, Tseng P, Lin C, Hung C, Lin S, Su W et al (2009) NAD[P]H: quinone oxidoreductase 1, glutathione S-transferase M1, environmental tobacco smoke exposure, and childhood asthma. Mutat Res 67:53-58
53. Polonikov AV, Ivanov VP, Solodilova MA (2009) Genetic variation of genes for xenobiotic-metabolizing enzymes and risk of bronchial asthma: the importance of gene-gene and gene-environment interactions for disease susceptibility. J Hum Genet 54:440-449
54. Ozcan C, Tamer L, Ates NA, Görür K (2010) The glutathione-S-transferase gene polymorphisms (Gstt1, Gstm1, and Gstp1) in patients with non-allergic nasal polyposis. Eur Arch Otorhinolaryngol 267:227-232
55. Undarmaa S, Mashimo Y, Hattori S, Shimojo N, Fujita K, Miyatake A et al (2010) Replication of genetic association studies in asthma and related phenotypes. J Hum Genet 55:342-349
56. Abd El-Aal A, Nashar MM, El-Sissy AH (2011) Glutathione S-transferase T1 (GSTT1) and M1 (GSTM1) genes polymorphism and risk of bronchial asthma in children. Comp Clin Pathol. doi: 10.1007/s00580-011-1262-z
57. Hersoug LG, Brash-Andersen C, Husemoen LL, Siqsqaard T, Linneberg A (2011) The relationship of glutathione-S-transferases copy number variation and indoor air pollution to symptoms and markers of respiratory disease. Clin Respir J. doi: 10.1111/j.1752-699X.2011.00258.x
58. Mahmoud IM, Kassem HS, Abdel Wahab NH, Saad AA, Moez P (2011) The association between glutathione S-transferase P1 polymorphisms and asthma in Egyptians. Alexandria Med J 47:105-115
59. Tatarskyy PF, Chumachenko NG, Kucherenko AM, Gulkovskyi RV, Arabskaya LP, Smirnova OA et al (2011) Study on possible role of CYP1A1, GSTT1, GSTM1, GSTP1, NAT2 and ADRB2 genes polymorphisms in bronchial asthma development in children. Biopolym Cell 27:66-73
60. Karam RA, Pasha HF, El-Shal A, Rahman HMA, Gad DM (2012) Impact of glutathione-S-transferase gene polymorphisms on enzyme activity, lung function and bronchial asthma susceptibility in Egyptian children. Gene 497:314-319
61. Piacentini S, Polimanti R, Moscatelli B, Re MA, Manfellotto D, Fuciarelli M (2012) Lack of association between GSTM1, GSTP1 and GSTT1 gene polymorphisms and asthma in adult patients from Rome, Central Italy. J Investig Allergol Clin Immunol 22:252-256
62. Piacentini S, Verrotti A, Polimanti R, Giannini C, Saccucci P, Manfellotto D et al (2012) Functional polymorphisms of GSTA1 and GSTO2 genes associated with asthma in Italian children. Clin Chem Lab Med 50:311-315
63. Xi S, Guo L, Qi R et al (2006) Interaction of GSTM1, GSTT1 polymorphism and air pollution in asthma. J Environ Health. doi: 1001-5914.0.2006-01-005