Glutathione S-transferase genotype increases risk of progression from bronchial hyperresponsiveness to asthma in adults

Thorax

Volumn 63, Issue 4, 2008, Pages 322-328

  Imboden, M ^a,i   Rochat, T ^b,f   Brutsche, M ^c,i   Schindler, C ^d,f   Downs, S H ^d,f   Gerbase, M W ^b,f   Berger, W ^a,i   Probst Hensch, N M ^a,e,f,i   Ackermann Liebrich, U ^f   Gaspoz, J M ^g   Leuenberger, P ^f   Liu, L J S ^f   Barthelemy J C ^g   Bettschart, R ^f   Bircher, A ^f   Bolognini, G ^f   Brandli O ^f   Burdet, L ^f   Frey, M ^f   Gold, D ^f,g   Karrer, W ^f   Keller, R ^f   Knopfli B ^f   Kunzli N ^f   Neu, U ^f   Nicod, L ^f   Pons, M ^f   Russi, E ^f   Schmid Grendelmeyer, P ^f   Schwartz, J ^f   Straehl, P ^f   Tschopp, J M ^f   Von Eckardstein, A ^h   Zellweger, J P ^f   Zemp Stutz, E ^f   Bridevaux, P O ^f   Curjuric, I ^f   Felber Dietrich, D ^g   Gemperli, A ^f   Keidel, D ^f   Staedele Kessler, P ^f   Thun, G A ⁱ   more..

^a UNIVERSITY OF ZURICH   (Switzerland)

^b GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^c UNIVERSITY HOSPITAL BASEL   (Switzerland)

^d SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

^e UNIVERSITY OF ZURICH   (Switzerland)

^f Allergology ^*

^g Cardiology

^h Clinical Chemistry   (Sweden)

ⁱ Genetic and Molecular Biology

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE TRANSFERASE; METHACHOLINE;

ADULT; ARTICLE; ASTHMA; BRONCHIAL HYPERRESPONSIVENESS; CONFIDENCE INTERVAL; DIAGNOSTIC ACCURACY; DISEASE COURSE; FEMALE; FOLLOW UP; FORCED EXPIRATORY VOLUME; GENE; GENE DELETION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENOTYPE; GSTM1 GENE; GSTT1 GENE; HUMAN; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL SIGNIFICANCE; SYMPTOM;

ADULT; ASTHMA; BRONCHIAL HYPERREACTIVITY; BRONCHOCONSTRICTOR AGENTS; COHORT STUDIES; DISEASE PROGRESSION; FEMALE; GENOTYPE; GLUTATHIONE TRANSFERASE; HUMANS; MALE; METHACHOLINE CHLORIDE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROSPECTIVE STUDIES; RISK FACTORS;

EID: 41849106861     PISSN: 00406376     EISSN: None     Source Type: Journal    
DOI: 10.1136/thx.2007.085555     Document Type: Article

References (61)

1. Grootendorst DC, Rabe KF. Mechanisms of bronchial hyperreactivity in asthma and chronic obstructive pulmonary disease. Proc Am Thorac Soc 2004;1:77-87.
2. Laprise C, Laviolette M, Boutet M, et al. Asymptomatic airway hyperresponsiveness: relationships with airway inflammation and remodelling. Eur Respir J 1999;14:63-73.
3. Brutsche MH, Downs SH, Schindler C, et al. Bronchial hyperresponsiveness and the development of asthma and COPD in asymptomatic individuals: SAPALDIA cohort study. Thorax 2006;61:671-7.
4. Sistek D, Wickens K, Amstrong R, et al. Predictive value of respiratory symptoms and bronchial hyperresponsiveness to diagnose asthma in New Zealand. Respir Med 2006;100:2107-11.
5. Xu X, Rijcken B, Schouten JP, et al. Airways responsiveness and development and remission of chronic respiratory symptoms in adults. Lancet 1997;350:1431-4.
6. Southam DS, Ellis R, Wattie J, et al. Components of airway hyperresponsiveness and their associations with inflammation and remodeling in mice. J Allergy Clin Immunol 2007;119:848-54.
7. Strange RC, Spiteri MA, Ramachandran S, et al. Glutathione-S-transferase family of enzymes. Mutat Res 2001;482:21-6.
8. Hayes JD, Strange RC. Potential contribution of the glutathione S-transferase supergene family to resistance to oxidative stress. Free Radic Res 1995;22:193-207.
9. Fryer AA, Hume R, Strange RC. The development of glutathione S-transferase and glutathione peroxidase activities in human lung. Biochim Biophys Acta 1986;883:448-53.
10. Gilliland FD, Gauderman WJ, Vora H, et al. Effects of glutathione-S-transferase M1, T1, and P1 on childhood lung function growth. Am J Respir Crit Care Med 2002;166:710-6.
11. Gilliland FD, Rappaport EB, Berhane K, et al. Effects of glutathione S-transferase P1, M1, and T1 on acute respiratory illness in school children. Am J Respir Crit Care Med 2002;166:346-51.
12. Imboden M, Downs SH, Senn O, et al. Glutathione S-transferase genotypes modify lung function decline in the general population: SAPALDIA cohort study. Respir Res 2007;8:2.
13. He JQ, Ruan J, Connett JE, et al. Antioxidant gene polymorphisms and susceptibility to a rapid decline in lung function in smokers. Am J Respir Crit Care Med 2002;166:323-8.
14. He JQ, Connett JE, Anthonisen NR, et al. Glutathione S-transferase variants and their interaction with smoking on lung function. Am J Respir Crit Care Med 2004;170:388-94.
15. Hayes JD, Strange RC. Glutathione S-transferase polymorphisms and their biological consequences. Pharmacology 2000;61:154-66.
16. Fryer AA, Bianco A, Hepple M, et al. Polymorphism at the glutathione S-transferase GSTP1 locus. A new marker for bronchial hyperresponsiveness and asthma. Am J Respir Crit Care Med 2000;161:1437-42.
17. Spiteri MA, Bianco A, Strange RC, et al. Polymorphisms at the glutathione S-transferase, GSTP1 locus: a novel mechanism for susceptibility and development of atopic airway inflammation. Allergy 2000;55(Suppl 61):15-20.
18. Martin BW, Ackermann-Liebrich U, Leuenberger P, et al. SAPALDIA: methods and participation in the cross-sectional part of the Swiss Study on Air Pollution and Lung Diseases in Adults. Soz Praventivmed 1997;42:67-84.
19. Ackermann-Liebrich U, Kuna-Dibbert B, Probst-Hensch N, et al. Follow-up of the Swiss Cohort Study on Air Pollution and Lung Diseases in Adults (SAPALDIA 2) 1991-2003: methods and characterization of participants. Soz Praventiv Med 2005;50:245-63.
20. Kunzli N, Kuna-Dibbert B, Keidel D, et al. Longitudinal validity of spirometers - a challenge in lung function follow-up studies. Swiss Medical Weekly 2005;135:503-8.
21. Leuenberger P, Schindler C, Schwartz J, et al. Occupational exposure to inhalative irritants and methacholine responsiveness. Scand J Work Environ Health 2000;26:146-52.
22. O'Connor G, Sparrow D, Taylor D, et al. Analysis of dose-response curves to methacholine. An approach suitable for population studies. Am Rev Respir Dis 1987;136:1412-7.
23. Schwartz J, Schindler C, Zemp E, et al. Predictors of methacholine responsiveness in a general population. Chest 2002;122:812-20.
24. Wuthrich B, Schindler C, Medici TC, et al. IgE levels, atopy markers and hay fever in relation to age, sex and smoking status in a normal adult Swiss population. SAPALDIA (Swiss Study on Air Pollution and Lung Diseases in Adults) Team. Int Arch Allergy Immunol 1996;111:396- 402.
25. Burney PG, Luczynska C, Chinn S, et al. The European Community Respiratory Health Survey. Eur Respir J 1994;7:954-60.
26. Schneider S, Roessli D, Excoffier L. Arlequin ver 2000: A software for population genetics data analysis. Switzerland: Genetics & Biometry Laboratory, University of Geneva, 2000.
27. Fleiss JL. Analysis of data from multiclinic trials. Control Clin Trials 1986;7:267-75.
28. Kelada SN, Kardia SL, Walker AH, et al. The glutathione S-transferase-mu and -theta genotypes in the etiology of prostate cancer: genotype-environment interactions with smoking. Cancer Epidemiol Biomarkers Prev 2000;9:1329-34.
29. James A, Carroll N. Airway smooth muscle in health and disease; methods of measurement and relation to function. Eur Respir J 2000;15:782-9.
30. Dulin NO, Fernandes DJ, Dowell M, et al. What evidence implicates airway smooth muscle in the cause of BHR? Clin Rev Allergy Immunol 2003;24:73-84.
31. Shore SA, Fredberg JJ. Obesity, smooth muscle, and airway hyperresponsiveness. J Allergy Clin Immunol 2005;115:925-7.
32. Boulet LP, Laviolette M, Turcotte H, et al. Bronchial subepithelial fibrosis correlates with airway responsiveness to methacholine. Chest 1997;112:45-52.
33. Chetta A, Foresi A, Del Donno M, et al. Airways remodeling is a distinctive feature of asthma and is related to severity of disease. Chest 1997;111:852-7.
34. Prezant DJ, Weiden M, Banauch GI, et al. Cough and bronchial responsiveness in firefighters at the World Trade Center site. N Engl J Med 2002;347:806-15.
35. Gilmour MI, Jaakkola MS, London SJ, et al. How exposure to environmental tobacco smoke, outdoor air pollutants, and increased pollen burdens influences the incidence of asthma. Environ Health Perspect 2006;114:627-33.
36. Henriksen AH, Sue-Chu M, Holmen TL, et al. Exhaled and nasal NO levels in allergic rhinitis: relation to sensitization, pollen season and bronchial hyperresponsiveness. Eur Respir J 1999;13:301-6.
37. Kohlhaufl M, Brand P, Scheuch G, et al. Increased fine particle deposition in women with asymptomatic nonspecific airway hyperresponsiveness. Am J Respir Crit Care Med 1999;159:902-6.
38. Lau S, Illi S, Platts-Mills TA, et al. Longitudinal study on the relationship between cat allergen and endotoxin exposure, sensitization, cat-specific IgG and development of asthma in childhood: report of the German Multicentre Allergy Study (MAS 90). Allergy 2005;60:766-73.
39. Sterk PJ, Fabbri LM, Quanjer PH, et al. Airway responsiveness. Standardized challenge testing with pharmacological, physical and sensitizing stimuli in adults. Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. Official Statement of the European Respiratory Society. Eur Respir J Suppl 1993;16:53-83.
40. Gerbase MW, Schindler C, Zellweger JP, et al. Respiratory effects of environmental tobacco exposure are enhanced by bronchial hyperreactivity. Am J Respir Crit Care Med 2006;174:1125-31.
41. Hayes JD, Pulford DJ. The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance. Crit Rev Biochem Mol Biol 1995;30:445-600.
42. Adler V, Yin Z, Fuchs SY, et al. Regulation of JNK signaling by GSTp. Embo J 1999;18:1321-34.
43. Ruscoe JE, Rosario LA, Wang T, et al. Pharmacologic or genetic manipulation of glutathione S-transferase P1-1 (GSTpi) influences cell proliferation pathways. J Pharmacol Exp Ther 2001;298:339-45.
44. Elsby R, Kitteringham NR, Goldring CE, et al. Increased constitutive c-Jun N-terminal kinase signaling in mice lacking glutathione S-transferase Pi. J Biol Chem 2003;278:22243-9.
45. Henderson CJ, Smith AG, Ure J, et al. Increased skin tumorigenesis in mice lacking pi class glutathione S-transferases. Proc Natl Acad Sci USA 1998;95:5275-80.
46. Postma DS, Boezen HM. Rationale for the Dutch hypothesis. Allergy and airway hyperresponsiveness as genetic factors and their interaction with environment in the development of asthma and COPD. Chest 2004;126(2 Suppl):96-104S; discussion 159-61S.
47. Nowak D, Jorres R, Schmidt A, et al. Effect of 3 hours' passive smoke exposure in the evening on airway tone and responsiveness until next morning. Int Arch Occup Environ Health 1997;69:125-33.
48. Nowak D, Jorres R, Martinez-Muller L, et al. Effect of 3 hours of passive smoke exposure in the evening on inflammatory markers in bronchoalveolar and nasal lavage fluid in subjects with mild asthma. Int Arch Occup Environ Health 1997;70:85-93.
49. Feleszko W, Zawadzka-Krajewska A, Matysiak K, et al. Parental tobacco smoking is associated with augmented IL-13 secretion in children with allergic asthma. J Allergy Clin Immunol 2006;117:97-102.
50. Cheng YK, Tsai MH, Lin CD, et al. Oxidative stress in nonallelic nasal polyps associated with bronchial hyperresponsiveness. Allergy 2006;61:1290-8.
51. Aynacioglu AS, Nacak M, Filiz A, et al. Protective role of glutathione S-transferase P1 (GSTP1) Val105Val genotype in patients with bronchial asthma. Br J Clin Pharmacol 2004;57:213-7.
52. Lee YL, Lin YC, Lee YC, et al. Glutathione S-transferase P1 gene polymorphism and air pollution as interactive risk factors for childhood asthma. Clin Exp Allergy 2004;34:1707-13.
53. Lee YL, Hsiue TR, Lee YC, et al. The association between glutathione s-transferase P1, M1 polymorphisms and asthma in Taiwanese schoolchildren. Chest 2005;128:1156-62.
54. Carroll WD, Lenney W, Jones PW, et al. Effects of glutathione S-transferase M1, T1 and P1 on lung function in asthmatic families. Clin Exp Allergy 2005;35:1155-61.
55. Ivaschenko TE, Sideleva OG, Baranov VS. Glutathione- S-transferase micro and theta gene polymorphisms as new risk factors of atopic bronchial asthma. J Mol Med 2002;80:39-43.
56. Tamer L, Calikoglu M, Ates NA, et al. Glutathione-S- transferase gene polymorphisms (GSTT1, GSTM1, GSTP1) as increased risk factors for asthma. Respirology 2004;9:493-8.
57. Kabesch M, Hoefler C, Carr D, et al. Glutathione S transferase deficiency and passive smoking increase childhood asthma. Thorax 2004;59:569-73.
58. Romieu I, Sienra-Monge JJ, Ramirez-Aguilar M, et al. Genetic polymorphism of GSTM1 and antioxidant supplementation influence lung function in relation to ozone exposure in asthmatic children in Mexico City. Thorax 2004;59:8-10.
59. Pekkanen J, Pearce N. Defining asthma in epidemiological studies. Eur Respir J 1999;14:951-7.
60. Toren K, Brisman J, Jarvholm B. Asthma and asthma-like symptoms in adults assessed by questionnaires. A literature review. Chest 1993;104:600-8.
61. Britton J, Pavord I, Richards K, et al. Factors influencing the occurrence of airway hyperreactivity in the general population: the importance of atopy and airway calibre. Eur Respir J 1994;7:881-7.