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Volumn 452, Issue 3, 2013, Pages 585-594

Membrane topology of yeast alkaline ceramidase YPC1

Author keywords

Ceramidase; CREST superfamily; Cysteine residue accessibility; Topology; Yeast phyto ceramidase 1 (YPC1)

Indexed keywords

ACYL COENZYME A; ALKALINE CERAMIDASE; CYSTEINE; DISULFIDE; LYSINE; UNCLASSIFIED DRUG; YEAST PHYTOCERAMIDASE 1;

EID: 84878394601     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20130085     Document Type: Article
Times cited : (5)

References (47)
  • 1
    • 78049504286 scopus 로고    scopus 로고
    • Roles for sphingolipids in Saccharomyces cerevisiae
    • Dickson, R. C. (2010) Roles for sphingolipids in Saccharomyces cerevisiae. Adv. Exp. Med. Biol. 688, 217-231
    • (2010) Adv. Exp. Med. Biol. , vol.688 , pp. 217-231
    • Dickson, R.C.1
  • 2
    • 0034670379 scopus 로고    scopus 로고
    • Identification of ISC1 (YERO19w) as inositol phosphosphingolipid phospholipase C in Saccharomyces cerevisiae
    • DOI 10.1074/jbc.M007721200
    • Sawai, H., Okamoto, Y., Luberto, C., Mao, C., Bielawska, A., Domae, N. and Hannun, Y. A. (2000) Identification of ISC1 (YER019w) as inositol phosphosphingolipid phospholipase C in Saccharomyces cerevisiae. J. Biol. Chem. 275, 39793-39798 (Pubitemid 32059011)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.50 , pp. 39793-39798
    • Sawai, H.1    Okamoto, Y.2    Luberto, C.3    Mao, C.4    Bielawska, A.5    Domae, N.6    Hannun, Y.A.7
  • 3
    • 0035355508 scopus 로고    scopus 로고
    • C26-CoA-dependent ceramide synthesis of Saccharomyces cerevisiae is operated by Lag1p and Lac1p
    • DOI 10.1093/emboj/20.11.2655
    • Guillas, I., Kirchman, P. A., Chuard, R., Pfefferli, M., Jiang, J. C., Jazwinski, S. M. and Conzelmann, A. (2001) C26-CoA-dependent ceramide synthesis of Saccharomyces cerevisiae is operated by Lag1p and Lac1p. EMBO J. 20, 2655-2665 (Pubitemid 32938550)
    • (2001) EMBO Journal , vol.20 , Issue.11 , pp. 2655-2665
    • Guillas, I.1    Kirchman, P.A.2    Chuard, R.3    Pfefferli, M.4    Jiang, J.C.5    Jazwinski, S.M.6    Conzelmann, A.7
  • 4
    • 0032429260 scopus 로고    scopus 로고
    • Homologs of the yeast longevity gene LAG1 in Caenorhabditis elegans and human
    • Jiang, J. C., Kirchman, P. A., Zagulski, M., Hunt, J. and Jazwinski, S. M. (1998) Homologs of the yeast longevity gene LAG1 in Caenorhabditis elegans and human. Genome Res. 8, 1259-1272 (Pubitemid 29039098)
    • (1998) Genome Research , vol.8 , Issue.12 , pp. 1259-1272
    • Jiang, J.C.1    Kirchman, P.A.2    Zagulski, M.3    Hunt, J.4    Michal, J.S.5
  • 5
    • 0035197535 scopus 로고    scopus 로고
    • Lag1p and Lac1p are essential for the Acyl-CoA-dependent ceramide synthase reaction in Saccharomyces cerevisae
    • Schorling, S., Vallee, B., Barz, W. P., Riezman, H. and Oesterhelt, D. (2001) Lag1p and Lac1p are essential for the acyl-CoA-dependent ceramide synthase reaction in Saccharomyces cerevisae. Mol. Biol. Cell 12, 3417-3427 (Pubitemid 33108475)
    • (2001) Molecular Biology of the Cell , vol.12 , Issue.11 , pp. 3417-3427
    • Schorling, S.1    Vallee, B.2    Barz, W.P.3    Riezman, H.4    Oesterhelt, D.5
  • 6
    • 0036682881 scopus 로고    scopus 로고
    • TRAM, LAG1 and CLN8: Members of a novel family of lipid-sensing domains?
    • DOI 10.1016/S0968-0004(02)02154-0, PII S0968000402021540
    • Winter, E. and Ponting, C. P. (2002) TRAM, LAG1 and CLN8: members of a novel family of lipid-sensing domains? Trends Biochem. Sci. 27, 381-383 (Pubitemid 34874742)
    • (2002) Trends in Biochemical Sciences , vol.27 , Issue.8 , pp. 381-383
    • Winter, E.1    Ponting, C.P.2
  • 7
    • 15444364432 scopus 로고    scopus 로고
    • Lip1p: A novel subunit of acyl-CoA ceramide synthase
    • DOI 10.1038/sj.emboj.7600562
    • Vallee, B. and Riezman, H. (2005) Lip1p: a novel subunit of acyl-CoA ceramide synthase. EMBO J. 24, 730-741 (Pubitemid 40396103)
    • (2005) EMBO Journal , vol.24 , Issue.4 , pp. 730-741
    • Vallee, B.1    Riezman, H.2
  • 8
    • 0032910193 scopus 로고    scopus 로고
    • Two endoplasmic reticulum (ER) membrane proteins that facilitate ER-to-Golgi transport of glycosylphosphatidylinositol-anchored proteins
    • Barz, W. P. and Walter, P. (1999) Two endoplasmic reticulum (ER) membrane proteins that facilitate ER-to-Golgi transport of glycosylphosphatidylinositol- anchored proteins. Mol. Biol. Cell 10, 1043-1059 (Pubitemid 29193730)
    • (1999) Molecular Biology of the Cell , vol.10 , Issue.4 , pp. 1043-1059
    • Barz, W.P.1    Walter, P.2
  • 9
    • 33748742094 scopus 로고    scopus 로고
    • Transmembrane topology of ceramide synthase in yeast
    • DOI 10.1042/BJ20060697
    • Kageyama-Yahara, N. and Riezman, H. (2006) Transmembrane topology of ceramide synthase in yeast. Biochem. J. 398, 585-593 (Pubitemid 44453404)
    • (2006) Biochemical Journal , vol.398 , Issue.3 , pp. 585-593
    • Kageyama-Yahara, N.1    Riezman, H.2
  • 11
    • 34547947625 scopus 로고    scopus 로고
    • A Molecular Caliper Mechanism for Determining Very Long-Chain Fatty Acid Length
    • DOI 10.1016/j.cell.2007.06.031, PII S009286740700829X
    • Denic, V. and Weissman, J. S. (2007) A molecular caliper mechanism for determining very long-chain fatty acid length. Cell 130, 663-677 (Pubitemid 47268053)
    • (2007) Cell , vol.130 , Issue.4 , pp. 663-677
    • Denic, V.1    Weissman, J.S.2
  • 12
    • 21844477032 scopus 로고    scopus 로고
    • Rapid transbilayer movement of ceramides in phospholipid vesicles and in human erythrocytes
    • DOI 10.1074/jbc.M412052200
    • Lopez-Montero, I., Rodriguez, N., Cribier, S., Pohl, A., Velez, M. and Devaux, P. F. (2005) Rapid transbilayer movement of ceramides in phospholipid vesicles and in human erythrocytes. J. Biol. Chem. 280, 25811-25819 (Pubitemid 40962291)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.27 , pp. 25811-25819
    • Lopez-Montero, I.1    Rodriguez, N.2    Cribier, S.3    Pohl, A.4    Velez, M.5    Devaux, P.F.6
  • 13
    • 61349131380 scopus 로고    scopus 로고
    • Rapid transmembrane diffusion of ceramide and dihydroceramide spin-labelled analogues in the liquid ordered phase
    • Pohl, A., Lopez-Montero, I., Rouviere, F., Giusti, F. and Devaux, P. F. (2009) Rapid transmembrane diffusion of ceramide and dihydroceramide spin-labelled analogues in the liquid ordered phase. Mol. Membr. Biol. 26, 194-204
    • (2009) Mol. Membr. Biol. , vol.26 , pp. 194-204
    • Pohl, A.1    Lopez-Montero, I.2    Rouviere, F.3    Giusti, F.4    Devaux, P.F.5
  • 14
    • 0034629140 scopus 로고    scopus 로고
    • Cloning of an alkaline ceramidase from Saccharomyces cerevisiae. An enzyme with reverse (CoA-independent) ceramide synthase activity
    • DOI 10.1074/jbc.275.10.6876
    • Mao, C., Xu, R., Bielawska, A. and Obeid, L. M. (2000) Cloning of an alkaline ceramidase from Saccharomyces cerevisiae. An enzyme with reverse (CoA-independent) ceramide synthase activity. J. Biol. Chem. 275, 6876-6884 (Pubitemid 30146228)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.10 , pp. 6876-6884
    • Mao, C.1    Xu, R.2    Bielawska, A.3    Obeid, L.M.4
  • 15
    • 0034613279 scopus 로고    scopus 로고
    • Cloning and characterization of a Saccharomyces cerevisiae alkaline ceramidase with specificity for dihydroceramide
    • Mao, C., Xu, R., Bielawska, A., Szulc, Z. M. and Obeid, L. M. (2000) Cloning and characterization of a Saccharomyces cerevisiae alkaline ceramidase with specificity for dihydroceramide. J. Biol. Chem. 275, 31369-31378
    • (2000) J. Biol. Chem. , vol.275 , pp. 31369-31378
    • Mao, C.1    Xu, R.2    Bielawska, A.3    Szulc, Z.M.4    Obeid, L.M.5
  • 16
    • 3242673409 scopus 로고    scopus 로고
    • Suppressor analysis points to the subtle role of the LAG1 ceramide synthase gene in determining yeast longevity
    • DOI 10.1016/j.exger.2004.03.026, PII S0531556504001305
    • Jiang, J. C., Kirchman, P. A., Allen, M. and Jazwinski, S. M. (2004) Suppressor analysis points to the subtle role of the LAG1 ceramide synthase gene in determining yeast longevity. Exp. Gerontol. 39, 999-1009 (Pubitemid 38952880)
    • (2004) Experimental Gerontology , vol.39 , Issue.7 , pp. 999-1009
    • Jiang, J.C.1    Kirchman, P.A.2    Allen, M.3    Jazwinski, S.M.4
  • 18
    • 50049090026 scopus 로고    scopus 로고
    • Ceramidases: Regulators of cellular responses mediated by ceramide, sphingosine, and sphingosine-1-phosphate
    • Mao, C. and Obeid, L. M. (2008) Ceramidases: regulators of cellular responses mediated by ceramide, sphingosine, and sphingosine-1-phosphate. Biochim. Biophys. Acta 1781, 424-434
    • (2008) Biochim. Biophys. Acta , vol.1781 , pp. 424-434
    • Mao, C.1    Obeid, L.M.2
  • 19
    • 77950578526 scopus 로고    scopus 로고
    • Substrate specificity, membrane topology, and activity regulation of human alkaline ceramidase 2 (ACER2)
    • Sun, W., Jin, J., Xu, R., Hu, W., Szulc, Z. M., Bielawski, J., Obeid, L. M. and Mao, C. (2010) Substrate specificity, membrane topology, and activity regulation of human alkaline ceramidase 2 (ACER2). J. Biol. Chem. 285, 8995-9007
    • (2010) J. Biol. Chem. , vol.285 , pp. 8995-9007
    • Sun, W.1    Jin, J.2    Xu, R.3    Hu, W.4    Szulc, Z.M.5    Bielawski, J.6    Obeid, L.M.7    Mao, C.8
  • 20
    • 33748746334 scopus 로고    scopus 로고
    • When do Lasses (longevity assurance genes) become CerS (ceramide synthases)? Insights into the regulation of ceramide synthesis
    • DOI 10.1074/jbc.R600010200
    • Pewzner-Jung, Y., Ben-Dor, S. and Futerman, A. H. (2006) When do Lasses (longevity assurance genes) become CerS (ceramide synthases)?: insights into the regulation of ceramide synthesis. J. Biol. Chem. 281, 25001-25005 (Pubitemid 44401887)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.35 , pp. 25001-25005
    • Pewzner-Jung, Y.1    Ben-Dor, S.2    Futerman, A.H.3
  • 21
    • 79960893835 scopus 로고    scopus 로고
    • CREST: A large and diverse superfamily of putative transmembrane hydrolases
    • Pei, J., Millay, D. P., Olson, E. N. and Grishin, N. V. (2011) CREST: a large and diverse superfamily of putative transmembrane hydrolases. Biol. Direct 6, 37
    • (2011) Biol. Direct , vol.6 , pp. 37
    • Pei, J.1    Millay, D.P.2    Olson, E.N.3    Grishin, N.V.4
  • 22
    • 0036275447 scopus 로고    scopus 로고
    • Getting started with yeast
    • Sherman, F. (2002) Getting started with yeast. Methods Enzymol. 350, 3-41
    • (2002) Methods Enzymol. , vol.350 , pp. 3-41
    • Sherman, F.1
  • 23
    • 84870235871 scopus 로고    scopus 로고
    • Topology of the microsomal glycerol-3-phosphate acyltransferase Gpt2p/Gat1p of Saccharomyces cerevisiae
    • Pagac, M., Vazquez, H. M., Bochud, A., Roubaty, C., Knopfli, C., Vionnet, C. and Conzelmann, A. (2012) Topology of the microsomal glycerol-3-phosphate acyltransferase Gpt2p/Gat1p of Saccharomyces cerevisiae. Mol. Microbiol. 86, 1156-1166
    • (2012) Mol. Microbiol. , vol.86 , pp. 1156-1166
    • Pagac, M.1    Vazquez, H.M.2    Bochud, A.3    Roubaty, C.4    Knopfli, C.5    Vionnet, C.6    Conzelmann, A.7
  • 25
    • 12344282919 scopus 로고    scopus 로고
    • Drag&Drop cloning in yeast
    • DOI 10.1016/j.gene.2004.10.016, PII S0378111904006420
    • Jansen, G., Wu, C., Schade, B., Thomas, D. Y. and Whiteway, M. (2005) Drag&Drop cloning in yeast. Gene 344, 43-51 (Pubitemid 40126791)
    • (2005) Gene , vol.344 , pp. 43-51
    • Jansen, G.1    Wu, C.2    Schade, B.3    Thomas, D.Y.4    Whiteway, M.5
  • 26
    • 84873131548 scopus 로고    scopus 로고
    • Adaptation of low-resolution methods for the study of yeast microsomal polytopic membrane proteins: A methodological review
    • Bochud, A., Ramachandra, N. and Conzelmann, A. (2013) Adaptation of low-resolution methods for the study of yeast microsomal polytopic membrane proteins: a methodological review. Biochem. Soc. Trans. 41, 35-42
    • (2013) Biochem. Soc. Trans. , vol.41 , pp. 35-42
    • Bochud, A.1    Ramachandra, N.2    Conzelmann, A.3
  • 27
    • 80054685861 scopus 로고    scopus 로고
    • Topology of 1-acyl-sn-glycerol-3-phosphate acyltransferases SLC1 and ALE1 and related membrane-bound O-acyltransferases (MBOATs) of Saccharomyces cerevisiae
    • Pagac, M., de la Mora, H. V., Duperrex, C., Roubaty, C., Vionnet, C. and Conzelmann, A. (2011) Topology of 1-acyl-sn-glycerol-3-phosphate acyltransferases SLC1 and ALE1 and related membrane-bound O-acyltransferases (MBOATs) of Saccharomyces cerevisiae. J. Biol. Chem. 286, 36438-36447
    • (2011) J. Biol. Chem. , vol.286 , pp. 36438-36447
    • Pagac, M.1    De La Mora, H.V.2    Duperrex, C.3    Roubaty, C.4    Vionnet, C.5    Conzelmann, A.6
  • 28
    • 79953858620 scopus 로고    scopus 로고
    • Functional and topological analysis of yeast acyl-CoA:Diacylglycerol acyltransferase 2, an endoplasmic reticulum enzyme essential for triacylglycerol biosynthesis
    • Liu, Q., Siloto, R. M., Snyder, C. L. and Weselake, R. J. (2011) Functional and topological analysis of yeast acyl-CoA:diacylglycerol acyltransferase 2, an endoplasmic reticulum enzyme essential for triacylglycerol biosynthesis. J. Biol. Chem. 286, 13115-13126
    • (2011) J. Biol. Chem. , vol.286 , pp. 13115-13126
    • Liu, Q.1    Siloto, R.M.2    Snyder, C.L.3    Weselake, R.J.4
  • 29
    • 51049099817 scopus 로고    scopus 로고
    • Analysis of the membrane topology of transmembrane segments in the C-terminal hydrophobic domain of the yeast vacuolar ATPase subunit a (Vph1p) by chemical modification
    • Wang, Y., Toei, M. and Forgac, M. (2008) Analysis of the membrane topology of transmembrane segments in the C-terminal hydrophobic domain of the yeast vacuolar ATPase subunit a (Vph1p) by chemical modification. J. Biol. Chem. 283, 20696-20702
    • (2008) J. Biol. Chem. , vol.283 , pp. 20696-20702
    • Wang, Y.1    Toei, M.2    Forgac, M.3
  • 30
    • 84866423427 scopus 로고    scopus 로고
    • A novel pathway of ceramide metabolism in Saccharomyces cerevisiae
    • Voynova, N. S., Vionnet, C., Ejsing, C. S. and Conzelmann, A. (2012) A novel pathway of ceramide metabolism in Saccharomyces cerevisiae. Biochem. J. 447, 103-114
    • (2012) Biochem. J. , vol.447 , pp. 103-114
    • Voynova, N.S.1    Vionnet, C.2    Ejsing, C.S.3    Conzelmann, A.4
  • 31
    • 33646185061 scopus 로고    scopus 로고
    • Membrane topology of the yeast endoplasmic reticulum-localized ubiquitin ligase Doa10 and comparison with its human ortholog TEB4 (MARCH-VI)
    • DOI 10.1074/jbc.M512215200
    • Kreft, S. G., Wang, L. and Hochstrasser, M. (2006) Membrane topology of the yeast endoplasmic reticulum-localized ubiquitin ligase Doa10 and comparison with its human ortholog TEB4 (MARCH-VI). J. Biol. Chem. 281, 4646-4653 (Pubitemid 43847723)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.8 , pp. 4646-4653
    • Kreft, S.G.1    Wang, L.2    Hochstrasser, M.3
  • 33
    • 0032321487 scopus 로고    scopus 로고
    • Substituted-cysteine accessibility method
    • DOI 10.1016/S0076-6879(98)93011-7
    • Karlin, A. and Akabas, M. H. (1998) Substituted-cysteine accessibility method. Methods Enzymol. 293, 123-145 (Pubitemid 29342485)
    • (1998) Methods in Enzymology , vol.293 , pp. 123-145
    • Karlin, A.1    Akabas, M.H.2
  • 34
    • 19444377006 scopus 로고    scopus 로고
    • Transmembrane protein topology mapping by the substituted cysteine accessibility method (SCAM™): Application to lipid-specific membrane protein topogenesis
    • DOI 10.1016/j.ymeth.2004.11.002, PII S1046202305000459
    • Bogdanov, M., Zhang, W., Xie, J. and Dowhan, W. (2005) Transmembrane protein topology mapping by the substituted cysteine accessibility method (SCAM™): application to lipid-specific membrane protein topogenesis. Methods 36, 148-171 (Pubitemid 40726147)
    • (2005) Methods , vol.36 , Issue.2 SPEC. ISS. , pp. 148-171
    • Bogdanov, M.1    Zhang, W.2    Xie, J.3    Dowhan, W.4
  • 35
    • 0033601291 scopus 로고    scopus 로고
    • Lipid-assisted protein folding
    • Bogdanov, M. and Dowhan, W. (1999) Lipid-assisted protein folding. J. Biol. Chem. 274, 36827-36830
    • (1999) J. Biol. Chem. , vol.274 , pp. 36827-36830
    • Bogdanov, M.1    Dowhan, W.2
  • 36
    • 0029827249 scopus 로고    scopus 로고
    • Yeast Gpi8p is essential for GPI anchor attachment onto proteins
    • Benghezal, M., Benachour, A., Rusconi, S., Aebi, M. and Conzelmann, A. (1996) Yeast Gpi8p is essential for GPI anchor attachment onto proteins. EMBO J. 15, 6575-6583 (Pubitemid 26413790)
    • (1996) EMBO Journal , vol.15 , Issue.23 , pp. 6575-6583
    • Benghezal, M.1    Benachour, A.2    Rusconi, S.3    Aebi, M.4    Conzelmann, A.5
  • 39
    • 0030970048 scopus 로고    scopus 로고
    • Sphingolipid synthesis as a target for antifungal drugs. Complementation of the inositol phosphorylceramide synthase defect in a mutant strain of Saccharomyces cerevisiae by the AUR1 gene
    • DOI 10.1074/jbc.272.15.9809
    • Nagiec, M. M., Nagiec, E. E., Baltisberger, J. A., Wells, G. B., Lester, R. L. and Dickson, R. C. (1997) Sphingolipid synthesis as a target for antifungal drugs. Complementation of the inositol phosphorylceramide synthase defect in a mutant strain of Saccharomyces cerevisiae by the AUR1 gene. J. Biol. Chem. 272, 9809-9817 (Pubitemid 27171646)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.15 , pp. 9809-9817
    • Nagiec, M.M.1    Nagiec, E.E.2    Baltisberger, J.A.3    Wells, G.B.4    Lester, R.L.5    Dickson, R.C.6
  • 41
    • 0033944545 scopus 로고    scopus 로고
    • Inositol phosphorylceramide synthase is located in the Golgi apparatus of Saccharomyces cerevisiae
    • Levine, T. P., Wiggins, C. A. and Munro, S. (2000) Inositol phosphorylceramide synthase is located in the Golgi apparatus of Saccharomyces cerevisiae. Mol. Biol. Cell 11, 2267-2281 (Pubitemid 30489913)
    • (2000) Molecular Biology of the Cell , vol.11 , Issue.7 , pp. 2267-2281
    • Levine, T.P.1    Wiggins, C.A.R.2    Munro, S.3
  • 42
    • 35848950226 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae CWH43 is involved in the remodeling of the lipid moiety of GPI anchors to ceramides
    • DOI 10.1091/mbc.E07-05-0482
    • Umemura, M., Fujita, M., Yoko-O, T., Fukamizu, A. and Jigami, Y. (2007) Saccharomyces cerevisiae CWH43 is involved in the remodeling of the lipid moiety of GPI anchors to ceramides. Mol. Biol. Cell 18, 4304-4316 (Pubitemid 350060160)
    • (2007) Molecular Biology of the Cell , vol.18 , Issue.11 , pp. 4304-4316
    • Umemura, M.1    Fujita, M.2    Yoko-O, T.3    Fukamizu, A.4    Jigami, Y.5
  • 43
    • 34548348943 scopus 로고    scopus 로고
    • CWH43 is required for the introduction of ceramides into GPI anchors in Saccharomyces cerevisiae
    • DOI 10.1111/j.1365-2958.2007.05883.x
    • Ghugtyal, V., Vionnet, C., Roubaty, C. and Conzelmann, A. (2007) CWH43 is required for the introduction of ceramides into GPI anchors in Saccharomyces cerevisiae. Mol. Microbiol. 65, 1493-1502 (Pubitemid 47347832)
    • (2007) Molecular Microbiology , vol.65 , Issue.6 , pp. 1493-1502
    • Ghugtyal, V.1    Vionnet, C.2    Roubaty, C.3    Conzelmann, A.4
  • 44
    • 84864863755 scopus 로고    scopus 로고
    • The topology of the triacylglycerol synthesizing enzyme Lro1 indicates that neutral lipids can be produced within the luminal compartment of the endoplasmatic reticulum: Implications for the biogenesis of lipid droplets
    • Choudhary, V., Jacquier, N. and Schneiter, R. (2011) The topology of the triacylglycerol synthesizing enzyme Lro1 indicates that neutral lipids can be produced within the luminal compartment of the endoplasmatic reticulum: implications for the biogenesis of lipid droplets. Commun. Integr. Biol. 4, 781-784
    • (2011) Commun. Integr. Biol. , vol.4 , pp. 781-784
    • Choudhary, V.1    Jacquier, N.2    Schneiter, R.3
  • 45
  • 46
    • 33748665711 scopus 로고    scopus 로고
    • Golgi alkaline ceramidase regulates cell proliferation and survival by controlling levels of sphingosine and S1P
    • DOI 10.1096/fj.05-5689com
    • Xu, R., Jin, J., Hu, W., Sun, W., Bielawski, J., Szulc, Z., Taha, T., Obeid, L. M. and Mao, C. (2006) Golgi alkaline ceramidase regulates cell proliferation and survival by controlling levels of sphingosine and S1P. FASEB J. 20, 1813-1825 (Pubitemid 44933795)
    • (2006) FASEB Journal , vol.20 , Issue.11 , pp. 1813-1825
    • Xu, R.1    Jin, J.2    Hu, W.3    Sun, W.4    Bielawski, J.5    Szulc, Z.6    Taha, T.7    Obeid, L.M.8    Mao, C.9


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