Association between interleukin-18 polymorphisms and systemic lupus erythematosus: A meta-analysis

Molecular Biology Reports

Volumn 40, Issue 3, 2013, Pages 2581-2587

  Song, Gwan Gyu ^a   Choi, Sung Jae ^a   Ji, Jong Dae ^a   Lee, Young Ho ^a  

^a College of Medicine   (South Korea)

Author keywords

Interleukin 18; Meta analysis; Polymorphism; Systemic lupus erythematosus

Indexed keywords

INTERLEUKIN 18;

ALLELE; ARTICLE; ASIAN; DISEASE PREDISPOSITION; ETHNIC GROUP; ETHNICITY; EUROPEAN; GENE; GENETIC ASSOCIATION; GENETIC HETEROGENEITY; GENETIC POLYMORPHISM; HUMAN; IL 18 GENE; PATHOGENESIS; PROMOTER REGION; SYSTEMATIC REVIEW; SYSTEMIC LUPUS ERYTHEMATOSUS;

ALLELES; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; INTERLEUKIN-18; LUPUS ERYTHEMATOSUS, SYSTEMIC; ODDS RATIO; POLYMORPHISM, GENETIC; PUBLICATION BIAS;

EID: 84878385877     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-012-2344-y     Document Type: Article

References (30)

1. Lee YH, Nath SK (2005) Systemic lupus erythematosus susceptibility loci defined by genome scan meta-analysis. Hum Genet 118:434-443
2. Kang SH, Chung BH, Choi SR, Lee JY, Park HS, Sun IO, Choi BS, Park CW, Kim YS, Yang CW (2011) Comparison of clinical outcomes by different renal replacement therapy in patients with end-stage renal disease secondary to lupus nephritis. Korean J Intern Med 26:60-67
3. Boraschi D, Dinarello CA (2006) IL-18 in autoimmunity: review. Eur Cytokine Netw 17:224-252
4. Amerio P, Frezzolini A, Abeni D, Teofoli P, Girardelli CR, De Pita O, Puddu P (2002) Increased IL-18 in patients with systemic lupus erythematosus: relations with Th-1, Th-2, pro-inflammatory cytokines and disease activity. IL-18 is a marker of disease activity but does not correlate with pro-inflammatory cytokines. Clin Exp Rheumatol 20:535-538
5. Wong CK, Ho CY, Li EK, Lam CW (2000) Elevation of proinflammatory cytokine (IL-18, IL-17, IL-12) and Th2 cytokine (IL-4) concentrations in patients with systemic lupus erythematosus. Lupus 9:589-593
6. Nolan KF, Greaves DR, Waldmann H (1998) The human interleukin 18 gene IL18 maps to 11q22.2-q22.3, closely linked to the DRD2 gene locus and distinct from mapped IDDM loci. Genomics 51:161-163
7. Haus-Seuffert P, Meisterernst M (2000) Mechanisms of transcriptional activation of cAMP-responsive element-binding protein CREB. Mol Cell Biochem 212:5-9
8. Giedraitis V, He B, Huang WX, Hillert J (2001) Cloning and mutation analysis of the human IL-18 promoter: a possible role of polymorphisms in expression regulation. J Neuroimmunol 112:146-152
9. Fishman D, Faulds G, Jeffery R, Mohamed-Ali V, Yudkin JS, Humphries S, Woo P (1998) The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis. J Clin Investig 102:1369-1376
10. Sanchez E, Palomino-Morales RJ, Ortego-Centeno N, Jimenez-Alonso J, Gonzalez-Gay MA, Lopez-Nevot MA, Sanchez-Roman J, de Ramon E, Gonzalez-Escribano MF, Pons-Estel BA, D'Alfonso S, Sebastiani GD, Alarcon-Riquelme ME, Martin J (2009) Identification of a new putative functional IL18 gene variant through an association study in systemic lupus erythematosus. Hum Mol Genet 18:3739-3748
11. Htoon J, Nadig A, Hughes T, Yavuz S, Direskeneli H, Saruhan-Direskeneli G, Sawalha AH (2011) IL18 polymorphism is associated with Behcet's disease but not lupus in patients from Turkey. J Rheumatol 38:962-963
12. Warchol T, Lianeri M, Olesinska M, Jagodzinski PP (2011) Interleukin-18 promoter polymorphisms in patients with systemic lupus erythematosus. Clin Exp Rheumatol 29:310-313
13. Guerra SG, Morris DL, Gateva V, Graham RR, Vyse TJ, Cunninghame Graham DS (2011) Dense mapping of IL18 shows no association in SLE. Hum Mol Genet 20:1026-1033
14. Chen DY, Hsieh CW, Chen KS, Chen YM, Lin FJ, Lan JL (2009) Association of interleukin-18 promoter polymorphisms with WHO pathological classes and serum IL-18 levels in Chinese patients with lupus nephritis. Lupus 18:29-37
15. Hirankarn N, Tangwattanachuleeporn M, Wongpiyabovorn J, Wongchinsri J, Avihingsanon Y (2009) Association of IL-18 gene polymorphism (-137C) with arthritis manifestations in SLE: combined effect with IFN gamma gene polymorphism (+874A). Clin Rheumatol 28:219-223
16. Lan Y, Wei YS, Tang XS, Qin J, Wu J, Qin JM (2008) Association of interleukin-18 gene polymorphism with genetic susceptibility to systematic lupus erythematosus in Guangxi Zhuang population. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 25:434-437
17. Xu Q, Tin SK, Sivalingam SP, Thumboo J, Koh DR, Fong KY (2007) Interleukin-18 promoter gene polymorphisms in Chinese patients with systemic lupus erythematosus: association with CC genotype at position -607. Ann Acad Med Singap 36:91-95
18. Lin YJ, Wan L, Lee CC, Huang CM, Tsai Y, Tsai CH, Shin TL, Chao K, Liu CM, Xiao JW, Tsai FJ (2007) Disease association of the interleukin-18 promoter polymorphisms in Taiwan Chinese systemic lupus erythematosus patients. Genes Immun 8:302-307
19. Lee YH, Rho YH, Choi SJ, Ji JD, Song GG, Nath SK, Harley JB (2007) The PTPN22 C1858T functional polymorphism and autoimmune diseases - a meta-analysis. Rheumatology (Oxf) 46:49-56
20. Lee YH, Harley JB, Nath SK (2006) Meta-analysis of TNF-alpha promoter -308 A/G polymorphism and SLE susceptibility. Eur J Hum Genet 14:364-371
21. Lee YH, Rho YH, Choi SJ, Ji JD, Song GG (2006) Association of TNF-alpha -308 G/A polymorphism with responsiveness to TNF-alpha-blockers in rheumatoid arthritis: a meta-analysis. Rheumatol Int 27:157-161
22. Egger M, Davey Smith G, Schneider M, Minder C (1997) Bias in meta-analysis detected by a simple, graphical test. BMJ 315:629-634
23. Duval S, Tweedie R (2000) Trim and fill: a simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis. Biometrics 56:455-463
24. Davey Smith G, Egger M (1997) Meta-analyses of randomised controlled trials. Lancet 350:1182
25. DerSimonian R, Laird N (1986) Meta-analysis in clinical trials. Control Clin Trials 7:177-188
26. Higgins JP, Thompson SG (2002) Quantifying heterogeneity in a meta-analysis. Stat Med 21:1539-1558
27. Warchol T, Lianeri M, Wudarski M, Lacki JK, Jagodzinski PP (2009) IL-18 105 A>C polymorphism contributes to renal manifestations in patients with SLE. Rheumatol Int 30:187-191
28. Lin YJ, Wan L, Sheu JJ, Huang CM, Lin CW, Lan YC, Lai CH, Hung CH, Tsai Y, Tsai CH, Lin TH, Chen CP, Tsai FJ (2008) A/C polymorphism in the interleukin-18 coding region among Taiwanese systemic lupus erythematosus patients. Lupus 17:124-127
29. Lee YH, Witte T, Momot T, Schmidt RE, Kaufman KM, Harley JB, Sestak AL (2005) The mannose-binding lectin gene polymorphisms and systemic lupus erythematosus: two case-control studies and a meta-analysis. Arthritis Rheum 52:3966-3974
30. Neumann D, Del Giudice E, Ciaramella A, Boraschi D, Bossu P (2001) Lymphocytes from autoimmune MRL lpr/lpr mice are hyperresponsive to IL-18 and overexpress the IL-18 receptor accessory chain. J Immunol 166:3757-3762