IL18 polymorphism is associated with behçet's disease but not lupus in patients from Turkey

Journal of Rheumatology

Volumn 38, Issue 5, 2011, Pages 962-963

  Htoon, Jasmine ^a   Nadig, Ajay ^a   Hughes, Travis ^a   Yavuz, Sule ^b   Direskeneli, Haner ^b   Saruhan Direskeneli, Güher ^c   Sawalha, Amr H ^a,d,e  

^a OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^b MARMARA UNIVERSITY   (Turkey)

^c ISTANBUL UNIVERSITY   (Turkey)

^d UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^e VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BEHCET DISEASE; CASE CONTROL STUDY; CONTROLLED STUDY; GENE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; IL18 GENE; LETTER; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROMOTER REGION; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTEMIC LUPUS ERYTHEMATOSUS; TURKEY (REPUBLIC);

BEHCET SYNDROME; CASE-CONTROL STUDIES; HUMANS; INTERLEUKIN-18; LUPUS ERYTHEMATOSUS, SYSTEMIC; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; TURKEY;

EID: 79955552803     PISSN: 0315162X     EISSN: 14992752     Source Type: Journal    
DOI: 10.3899/jrheum.101202     Document Type: Letter

References (14)

1. Sánchez E, Palomino-Morales RJ, Ortego-Centeno N, Jimenez-Alonso J, Gonzalez-Gay MA, Lopez-Nevot MA, et al. Identification of a new putative functional IL18 gene variant through an association study in systemic lupus erythematosus. Hum Mol Genet 2009;18:3739-48.
2. Nakanishi K, Yoshimoto T, Tsutsui H, Okamura H. Interleukin-18 regulates both Th1 and Th2 responses. Annu Rev Immunol 2001;19:423-74. (Pubitemid 32368042)
3. Esfandiari E, McInnes IB, Lindop G, Huang FP, Field M, Komai-Koma M, et al. A proinflammatory role of IL-18 in the development of spontaneous autoimmune disease. J Immunol 2001;167:5338-47. (Pubitemid 33009773)
4. Oztas MO, Onder M, Gurer MA, Bukan N, Sancak B. Serum interleukin 18 and tumour necrosis factor-alpha levels are increased in Behcet's disease. Clin Exp Dermatol 2005;30:61-3. (Pubitemid 40188321)
5. Park MC, Park YB, Lee SK. Elevated interleukin-18 levels correlated with disease activity in systemic lupus erythematosus. Clin Rheumatol 2004;23:225-9. (Pubitemid 38812201)
6. Musabak U, Pay S, Erdem H, Simsek I, Pekel A, Dinc A, et al. Serum interleukin-18 levels in patients with Behcet's disease. Is its expression associated with disease activity or clinical presentations? Rheumatol Int 2006;26:545-50.
7. Hochberg MC. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus [letter]. Arthritis Rheum 1997;40:1725.
8. International Study Group for Behçet's Disease. Criteria for diagnosis of Behçet's disease. Lancet 1990;335:1078.
9. Guerra SG, Morris DL, Gateva V, Graham RR, Vyse TJ, Cunninghame Graham DS. Dense mapping of IL18 shows no association in SLE. Hum Mol Genet 2010 Dec 23. [Epub ahead of print]
10. Keskin F, Pay S, Musabak U, Sagkan RI, Erdem H, Simsek I, et al. IL-18 promoter polymorphisms confer susceptibility to Behcet's disease, particularly to the mucocutaneous form, in a Turkish population. Clin Exp Rheumatol 2009;27 Suppl 53:S108-9.
11. Lee YJ, Kang SW, Park JJ, Bae YD, Lee EY, Lee EB, et al. Interleukin-18 promoter polymorphisms in patients with Behcet's disease. Hum Immunol 2006;67:812-8. (Pubitemid 44572598)
12. Jang WC, Park SB, Nam YH, Lee SS, Kim JW, Chang IS, et al. Interleukin-18 gene polymorphisms in Korean patients with Behcet's disease. Clin Exp Rheumatol 2005;23 Suppl 38:S59-63.
13. Palomino-Morales RJ, Vazquez-Rodriguez TR, Torres O, Morado IC, Castaneda S, Miranda-Filloy JA, et al. Association between IL-18 gene polymorphisms and biopsy-proven giant cell arteritis. Arthritis Res Ther 2010;12:R51.
14. Torres O, Palomino-Morales R, Miranda-Filloy JA, Vazquez-Rodriguez TR, Martin J, Gonzalez-Gay MA. IL-18 gene polymorphisms in Henoch-Schonlein purpura. Clin Exp Rheumatol 2010;28 Suppl 57:114.