Positive association of Apolipoprotein E4 polymorphism with recurrent pregnancy loss in Iranian patients

Journal of Assisted Reproduction and Genetics

Volumn 30, Issue 2, 2013, Pages 265-268

  Asgari, Nooshin ^a   Akbari, Mohammad Taghi ^b,c   Zare, Shohre ^c,d   Babamohammadi, Gholamreza ^c  

^a ISLAMIC AZAD UNIVERSITY   (Iran)

^b TARBIAT MODARES UNIVERSITY   (Iran)

^c Tehran Medical Genetics Laboratory   (Iran)

^d ISLAMIC AZAD UNIVERSITY   (Iran)

Author keywords

Apo E4 polymorphism; Apolipoprotein E; Recurrent pregnancy loss

Indexed keywords

APOLIPOPROTEIN E4; IMMUNOLOGIC FACTOR; RESTRICTION ENDONUCLEASE;

ADULT; ALLELE; ARTICLE; CASE CONTROL STUDY; CHROMOSOME ABERRATION; CONTROLLED STUDY; DNA EXTRACTION; DNA POLYMORPHISM; DNA SEQUENCE; ENDOCRINE DISEASE; ENVIRONMENTAL FACTOR; EXON; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENITAL SYSTEM DISEASE; GENOTYPE; HETEROZYGOSITY; HUMAN; INFECTION; IRAN; MAJOR CLINICAL STUDY; PREGNANCY; PRIORITY JOURNAL; REPRODUCTIVE HISTORY; RISK FACTOR;

ABORTION, HABITUAL; ADULT; APOLIPOPROTEIN E4; CASE-CONTROL STUDIES; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; HUMANS; IRAN; LIPID METABOLISM; POLYMORPHISM, GENETIC; PREGNANCY; RISK FACTORS;

EID: 84878366083     PISSN: 10580468     EISSN: 15737330     Source Type: Journal    
DOI: 10.1007/s10815-012-9897-5     Document Type: Article

References (27)

1. Stirrat GM. Recurrent miscarriage. Lancet. 1990;336:673-5.
2. Clifford K, Rai R, Regan L. Future pregnancy outcome in unexplained recurrent first trimester miscarriage. Hum Reprod. 1997;12:387-9. doi: 10.1093/humrep/12.2.387.
3. Toth B, Jeschke U, Rogenhofer N, Scholz C, Würfel W, Thaler CJ, Makrigiannakis A. Recurrent miscarriage: current concepts in diagnosis and treatment. J Reprod Immunol. 2010;85:25-32. doi: 10.1016/j.jri.2009.12.006.
4. Suzumori N, Sugiura Ogasawara M. Genetic factors as a causes of miscarriage. Curr Med Chem. 2010;17:3431-7.
5. Zammiti W, Mtiraoui N, Khairi H, Gris JC, Almawi WY, Mahjoub T. Associations between tumor necrosis factor-alpha and lymphotoxin-alpha polymorphisms and idiopathic recurrent miscarriage. Reproduction. 2008;135:397-403. doi: 10.1530/REP-07-0322.
6. Parveen F, Faridi RM, Das V, Tripathi G, Agrawal S. Genetic association of phase I and phase II detoxification genes with recurrent miscarriages among North Indian women. Mol Hum Reprod. 2010;16:207-14. doi: 10.1093/molehr/gap096.
7. Pabinger I. Thrombophilia and its impact on pregnancy. Thromb Res. 2009;123:S16-21. doi: 10.1016/S0049-3848(09)70128-8.
8. Stortoni P, Cecati M, Giannubilo SR, Sartini D, Turi A, Emanuelli M, Tranquilli AL. Placental thrombomodulin expression in recurrent miscarriage. Reprod Biol Endocrinol. 2010;8:1-5. doi: 10.1186/1477-7827-8-1.
9. Goodman C, Goodman CS, Hur J, Jeyendran RS, Coulam C. The association of apoprotein E polymorphisms with recurrent pregnancy loss. Am J Reprod Immunol. 2009;61:34-8. doi: 10.1016/j.fertnstert.2009.12.016.
10. Wernette-Hammond ME, Lauer SJ, Corsini A, Walker D, Taylor JM, Rall Jr SC. Glycosylation of human apolipoprotein E. The carbohydrate attachment site is threonine 194. J Biol Chem. 1989;15:9094-101.
11. Mahley RW. Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. Science. 1988;240:622-30. doi: 10.1126/science.3283935.
12. Nathan BP, Bellosta S, Sanan DA, Weisgraber KH, Mahley RW, Pitas RE. Differential effects on apolipoproteins E3 and E4 on neuronal growth in Vitro. Science. 1994;264:850-2. doi: 10.1126/science.8171342.
13. Mahley RW, Weisgraber KH, Huang Y. Apolipoprotein E: structure determines function, from atherosclerosis to Alzheimers disease to AIDS. J Lipid Res. 2009;50:S183-188. doi: 10.1194/jlr.R800069-JLR200.
14. Zhang H, Wu LM, Wu J. Cross-talk between apolipoprotein E and cytokines. Mediators Inflamm. 2011;2011:949072. doi: 10.1155/2011/949072.
15. Williams PJ, Broughton Pipkin F. The genetics of pre-eclampsia and other hypertensive disorders of pregnancy. Best Pract Res Clin Obstet Gynaecol. 2011;25:405-17. doi: 10.1016/j.bpobgyn.2011.02.007.
16. Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 1988;16:1215.
17. Zuo L, van Dyck CH, Luo X, Kranzler HR, Yang BZ, Gelernter J. Variation at APOE and STH loci and Alzheimer's disease. Behav Brain Funct. 2006;2:13-23. doi: 10.1186/1744-9081-2-13.
18. Mahley RW, Rall Jr SC. Apolipoprotein E: far more than a lipid transport protein. Annu Rev Genomics Hum Genet. 2000;1:507-37. doi: 10.1146/annurev.genom. 1.1.507.
19. Amundsen T, Ueland PM, Waage A. Plasma homocysteine levels in patients with deep venous thrombosis. Arterioscler Thromb Vasc Biol. 1995;15:1321-3. doi: 10.1161/01.ATV.15.9.1321.
20. Ozornek H, Ergin E, Jeyendran RS, Ozay AT, Pillai D, Coulam C. Is Apolipoprotein E codon 112 polymorphisms associated with recurrent pregnancy loss? Am J Reprod Immunol. 2010;64:87-92. doi: 10.1111/j.1600-0897.2010.00814.x.
21. Vassiliadis S, Ranella A, Papadimitriou L, Makrygiannakis A, Athanassakis I. Serum levels of pro and anti-inflammatory cytokines in non-pregnant women, during pregnancy, labour and abortion. Mediators Inflamm. 1998;7:69-72.
22. Jofre-Monseny L, Loboda A, Wagner AE, Huebbe P, Boesch-Saadatmandi C, Jozkowicz A, Minihane AM, Dulak J, Rimbach G. Effects of apoE genotype on macrophage inflammation and heme oxygenase-1 expression. Biochem Biophys Res Commun. 2007;357:319-24. doi: 10.1016/j.bbrc.2007.03.150.
23. Chaouat G, Menu E, de Smedt D, Khrihnan L, Hui L, Assal Meliani A, Martal J, Raghupathy R, Wegmann TG. The emerging role of IL-10 in pregnancy. Am J Reprod Immunol. 1996;35:325-9. doi: 10.1111/j.1600-0897.1996.tb00488.x.
24. Tziakas DN, Chalikias GK, Antonoglou CO, Veletza S, Tentes IK, Kortsaris AX, Hatseras DI, Kaski JC. Apolipoprotein E genotype and circulating interleukin-10 levels in patients with stable and unstable coronary artery disease. J Am Coll Cardiol. 2006;48:2471-81. doi: 10.1016/j.jacc.2006.08.032.
25. Yenicesu GI, Cetin M, Ozdemir O, Cetin A, Ozen F, Yenicesu C, Yildiz C, Kocak N. A Prospective Case-Control Study analyzes 12 thrombophilic gene mutations in turkish couples with recurrent pregnancy loss. Am J Reprod Immunol. 2010;63:126-36. doi: 10.1111/j.1600-0897.2009.00770.x.
26. Bianca S, Barrano B, Cutuli N, Indaco L, Cataliotti A, Milana G, Barone C, Ettore G. No association between apolipoprotein E polymorphisms and recurrent pregnancy loss. Fertil Steril. 2010;93:276. doi: 10.1016/j.fertnstert.2009.07. 971.
27. Goodman C, Coulam C, Jeyendran RS. Association of apolipoprotein E polymorphisms and recurrent pregnancy loss. Fertil Steril. 2010;93:e19. doi: 10.1016/j.fertnstert.2009.12.016.