Stabilization of zeylenone in rat plasma by the presence of esterase inhibitors and its LC-MS/MS assay for pharmacokinetic study

Biomedical Chromatography

Volumn 27, Issue 5, 2013, Pages 636-640

  Wei, Xiao Lan ^a   Han, Rong ^a   Hu, Xiao ^a   Quan, Li Hui ^a   Liu, Chun Yu ^a   Chang, Qi ^a   Liao, Yong Hong ^a  

^a INSTITUTE OF MEDICINAL PLANT DEVELOPMENT   (China)

Author keywords

Esterase inhibitors; Labile benzoate containing compound; Pharmacokinetics; Polymeric micelles

Indexed keywords

BODY FLUIDS; CONTROLLED DRUG DELIVERY; ENZYMES; ESTERS; FLUORINE COMPOUNDS; LIQUID CHROMATOGRAPHY; MICELLES; POSITIVE IONS; QUALITY CONTROL; RATS; STABILIZATION;

BIS(NITROPHENYL)PHOSPHATE; DICHLORVOS; ESTERASE INHIBITOR; LABILE BENZOATE-CONTAINING COMPOUND; LC-MS-MS; PHARMACOKINETIC STUDIES; PHENYLMETHANESULFONYL FLUORIDE; POLYMERIC MICELLE; RAT PLASMA; THENOYLTRIFLUOROACETONE;

PHARMACOKINETICS;

ACETIC ACID ETHYL ESTER; BENZYLSULFONYL FLUORIDE; DICHLORVOS; EDETIC ACID; ESTERASE INHIBITOR; FORMIC ACID; HERBACEOUS AGENT; THENOYLTRIFLUOROACETONE; UNCLASSIFIED DRUG; ZEYLENONE;

ACCURACY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; AREA UNDER THE CURVE; ARTICLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG CLEARANCE; DRUG ELIMINATION; DRUG SOLUTION; DRUG STABILITY; ELECTROSPRAY; ENZYME ACTIVITY; LIQUID CHROMATOGRAPHY; MALE; MICELLE; NONHUMAN; PLASMA CONCENTRATION-TIME CURVE; POLYMERIZATION; POSITIVE ION ELECTROSPRAY; QUALITY CONTROL; RAT; TANDEM MASS SPECTROMETRY;

RATTUS;

EID: 84876339024     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.2838     Document Type: Article

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