Acute cerebral ischaemia: Relationship between serum and cerebrospinal fluid orexin-a concentration and infarct volume

Journal of International Medical Research

Volumn 41, Issue 2, 2013, Pages 404-409

  Kotan, Dilcan ^a   Deniz, Orhan ^b   Aygul, Recep ^c   Yilidim, Abdulkadir ^c  

^a SAKARYA UNIVERSITY   (Turkey)

^b Yildirim Beyazid University   (Turkey)

^c ATATÜRK UNIVERSITY   (Turkey)

Author keywords

Cerebrospinal fluid; Infarct volume; Ischaemic stroke; Neuropeptide hormone; Orexin A

Indexed keywords

OREXIN A;

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; BRAIN INFARCTION SIZE; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN RADIOGRAPHY; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; FEMALE; HUMAN; MALE; NEUROIMAGING; PREDICTION; PROTEIN BLOOD LEVEL; PROTEIN CEREBROSPINAL FLUID LEVEL; PROTEIN DETERMINATION;

EID: 84878347681     PISSN: 03000605     EISSN: 14732300     Source Type: Journal    
DOI: 10.1177/0300060513477002     Document Type: Article

References (23)

1. Bergen DC. The world-wide burden of neurologic disease. Neurology 1996; 47: 21-25.
2. Sakurai T, Amemiya A, Ishii M, et al. Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell 1998; 92: 573-585.
3. Sakurai T. Orexin and orexin receptors. In: de Lecea L, Satcliffe JG (eds) Hypocretins integrators of Physiological Signals. Tokyo: Japan Science and Technology Corporation, 2005, pp.13-23.
4. Willie JT, Chemelli RM, Sinton CM, et al. To eat or to sleep? Orexin in the regulation on feeding and wakefulness. Annu Rev Neurosci 2001; 24: 429-458.
5. Nambu T, Sakurai T, Mizukami K, et al. Distribution of orexin neurons in the adult rat brain. Brain Res 1999; 827: 243-260.
6. Winsky-Sommerer R, Boutrel B and de Lecea L. Stress and arousal: the corticotrophin- releasing factor/hypocretin circuitry. Mol Neurobiol 2005; 32: 285-294.
7. Saper CB, Scammell TE and Lu J. Hypothalamic regulation of sleep and circadian rhythms. Nature 2005; 437: 1257-1263.
8. Fadel J and Deutch AY. Anatomical substrates of orexin-dopamine interactions: lateral hypothalamic projections to the ventral tegmental area. Neuroscience 2002; 111: 379-387.
9. Korotkova TM, Sergeeva OA, Eriksson KS, et al. Excitation of ventral tegmental area dopaminergic and nondopaminergic neurons by orexins/hypocretins. J Neuroscience 2003; 23: 7-11.
10. Beuckmann CT and Yanagisawa M. Orexins: from neuropeptides to energy homeostasis and sleep/wake regulation. J Mol Med (Berl) 2002; 80: 329-342.
11. Kiyashchenko LI, Mileykovskiy BY, Maidment N, et al. Release of hypocretin (orexin) during waking and sleep states. J Neurosci 2002; 22: 5282-5286.
12. Date Y, Ueta Y, Yamashita H, et al. Orexins, orexigenic hypothalamic peptides, interact with autonomic, neuroendocrine and neuroregulatory systems. Proc Natl Acad Sci USA 1999; 96: 748-753.
13. Kastin AJ and Akerstrom V. Orexin A but not orexin B rapidly enters brain from blood by simple diffusion. J Pharmacol Exp Ther 1999; 289: 219-223.
14. Ogden JA, Utley T and Mee EW. Neurological and psychosocial outcome 4 to 7 years after subarachnoid hemorrhage. Neurosurgery 1997; 41: 25-34.
15. Dohi K, Ripley B, Fujiki N, et al. CSF orexin-A/hypocretin-1 concentrations in patients with intracerebral hemorrhage (ICH). Regul Pept 2008; 145: 60-64.
16. Rejdak K, Petzold A, Lin L, et al. Decreased CSF hypocretin-1 (orexin-A) after acute haemorrhagic brain injury. J Neurol Neurosurg Psychiatry 2005; 76: 597-598.
17. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med 1995; 333: 1581-1587.
18. Mendall MA, Patel P, Ballam L, et al. C reactive protein and its relation to cardiovascular risk factors: a population based cross sectional study. BMJ 1996; 312: 1061-1065.
19. Pinto A, Tuttolomondo A, Di Raimondo D, et al. Cerebrovascular risk factors and clinical classification of strokes. Semin Vasc Med 2004; 4: 287-303.
20. Yuan LB, Dong HL, Zhang HP, et al. Neuroprotective effect of orexin-A is mediated by an increase of hypoxia-inducible factor-1 activity in rat. Anesthesiology 2011; 114: 340-354.
21. Ramar K and Surani S. The relationship between sleep disorders and stroke. Postgrad Med 2010; 122: 145-153.
22. Sakurai T, Mieda M and Tsujino N. The orexin system: roles in sleep/wake regulation. Ann N Y Acad Sci 2010; 1200: 149-161.
23. Kodama T, Lai YY and Siegel JM. Enhanced glutamate release during REM sleep in the rostromedial medulla as measured by in vivo microdialysis. Brain Res 1998; 780: 178-181