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Volumn 8, Issue 4, 2013, Pages 283-289

COPD and the metabolic syndrome: An intriguing association

Author keywords

COPD; Inflammation; Metabolism; Obesity

Indexed keywords

ADULT; CHRONIC OBSTRUCTIVE LUNG DISEASE; HUMAN; METABOLIC SYNDROME X; PATHOPHYSIOLOGY; REVIEW; RISK FACTOR;

EID: 84878333940     PISSN: 18280447     EISSN: 19709366     Source Type: Journal    
DOI: 10.1007/s11739-011-0700-x     Document Type: Review
Times cited : (50)

References (50)
  • 1
    • 84878329084 scopus 로고    scopus 로고
    • From the Global Strategy for the Diagnosis, Management and Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD), Available from
    • From the Global Strategy for the Diagnosis, Management and Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2007. Available from: http://www. goldcopd. org/.
    • (2007)
  • 3
  • 4
    • 78349263876 scopus 로고    scopus 로고
    • Efficacy of standard rehabilitation in COPD outpatients with comorbidities
    • Crisafulli E, Gorgone P, Vagaggini B et al (2010) Efficacy of standard rehabilitation in COPD outpatients with comorbidities. Eur Respir J 36: 1042-1048.
    • (2010) Eur Respir J , vol.36 , pp. 1042-1048
    • Crisafulli, E.1    Gorgone, P.2    Vagaggini, B.3
  • 5
    • 2442647863 scopus 로고    scopus 로고
    • Prevalence of the metabolic syndrome and its relation to all-cause and cardiovascular mortality in nondiabetic European men and women
    • DECODE Study Group
    • Hu G, Qiao Q, Tuomilehto J, Balkau B, Borch-Johnsen K, Pyorala K; DECODE Study Group (2004) Prevalence of the metabolic syndrome and its relation to all-cause and cardiovascular mortality in nondiabetic European men and women. Arch Intern Med. 164(10): 1066-1076.
    • (2004) Arch Intern Med , vol.164 , Issue.10 , pp. 1066-1076
    • Hu, G.1    Qiao, Q.2    Tuomilehto, J.3    Balkau, B.4    Borch-Johnsen, K.5    Pyorala, K.6
  • 6
    • 23844540985 scopus 로고    scopus 로고
    • The metabolic syndrome in patients with chronic obstructive pulmonary disease
    • Marquis K, Maltais F, Duguay V et al (2005) The metabolic syndrome in patients with chronic obstructive pulmonary disease. J Cardiopulm Rehabil 25: 226-232.
    • (2005) J Cardiopulm Rehabil , vol.25 , pp. 226-232
    • Marquis, K.1    Maltais, F.2    Duguay, V.3
  • 7
    • 70350088412 scopus 로고    scopus 로고
    • The metabolic syndrome in patients with chronic bronchitis and COPD: frequency and associated consequences for systemic inflammation and physical inactivity
    • Watz H, Waschki B, Kirsten A et al (2009) The metabolic syndrome in patients with chronic bronchitis and COPD: frequency and associated consequences for systemic inflammation and physical inactivity. Chest 136: 1039-1046.
    • (2009) Chest , vol.136 , pp. 1039-1046
    • Watz, H.1    Waschki, B.2    Kirsten, A.3
  • 8
    • 76149126470 scopus 로고    scopus 로고
    • Airflow obstruction and metabolic syndrome: the Guangzhou Biobank Cohort Study
    • Lam KB, Jordan RE, Jiang CQ et al (2010) Airflow obstruction and metabolic syndrome: the Guangzhou Biobank Cohort Study. Eur Respir J 35: 317-323.
    • (2010) Eur Respir J , vol.35 , pp. 317-323
    • Lam, K.B.1    Jordan, R.E.2    Jiang, C.Q.3
  • 9
    • 0037021505 scopus 로고    scopus 로고
    • The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men
    • Lakka HM, Laaksonen DE, Lakka TA et al (2002) The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men. JAMA 288: 2709-2716.
    • (2002) Jama , vol.288 , pp. 2709-2716
    • Lakka, H.M.1    Laaksonen, D.E.2    Lakka, T.A.3
  • 10
    • 0037463608 scopus 로고    scopus 로고
    • The metabolic syndrome: prevalence and associated risk factor findings in the US population from the Third National Health and Nutrition Examination Survey, 1988-1994
    • Park YW, Zhu S, Palaniappan L, Heshka S, Carnethon MR, Heymsfield SB (2003) The metabolic syndrome: prevalence and associated risk factor findings in the US population from the Third National Health and Nutrition Examination Survey, 1988-1994. Arch Intern Med 163: 427-436.
    • (2003) Arch Intern Med , vol.163 , pp. 427-436
    • Park, Y.W.1    Zhu, S.2    Palaniappan, L.3    Heshka, S.4    Carnethon, M.R.5    Heymsfield, S.B.6
  • 11
    • 33646799069 scopus 로고    scopus 로고
    • Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data
    • Lopez AD, Mathers CD, Ezzati M, Jamison DT, Murray CJ (2006) Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data. Lancet 367: 1747-1757.
    • (2006) Lancet , vol.367 , pp. 1747-1757
    • Lopez, A.D.1    Mathers, C.D.2    Ezzati, M.3    Jamison, D.T.4    Murray, C.J.5
  • 12
    • 63249135843 scopus 로고    scopus 로고
    • Lung function impairment and metabolic syndrome the critical role of abdominal obesity
    • Leone N, Courbon D, Thomas F et al (2009) Lung function impairment and metabolic syndrome the critical role of abdominal obesity. Am J Respir Crit Care Med 179: 509-516.
    • (2009) Am J Respir Crit Care Med , vol.179 , pp. 509-516
    • Leone, N.1    Courbon, D.2    Thomas, F.3
  • 13
    • 0029897355 scopus 로고    scopus 로고
    • Longitudinal effects of change in body mass on measurements of ventilatory capacity
    • Chinn DJ, Cotes JE, Reed JW (1996) Longitudinal effects of change in body mass on measurements of ventilatory capacity. Thorax 51: 699-704.
    • (1996) Thorax , vol.51 , pp. 699-704
    • Chinn, D.J.1    Cotes, J.E.2    Reed, J.W.3
  • 14
    • 0036428922 scopus 로고    scopus 로고
    • The relation of body mass index to asthma, chronic bronchitis, and emphysema
    • Guerra S, Sherrill DL, Bobadilla A, Martinez FD, Barbee RA (2002) The relation of body mass index to asthma, chronic bronchitis, and emphysema. Chest 122: 1256-1263.
    • (2002) Chest , vol.122 , pp. 1256-1263
    • Guerra, S.1    Sherrill, D.L.2    Bobadilla, A.3    Martinez, F.D.4    Barbee, R.A.5
  • 15
    • 77956635529 scopus 로고    scopus 로고
    • Association between low pulmonary function and metabolic risk factors in Korean adults: the Korean National Health and Nutrition Survey
    • Paek YJ, Jung KS, Hwang YI, Lee KS, Lee DR, Lee JU (2010) Association between low pulmonary function and metabolic risk factors in Korean adults: the Korean National Health and Nutrition Survey. Metabolism 59(9): 1300-1306.
    • (2010) Metabolism , vol.59 , Issue.9 , pp. 1300-1306
    • Paek, Y.J.1    Jung, K.S.2    Hwang, Y.I.3    Lee, K.S.4    Lee, D.R.5    Lee, J.U.6
  • 17
    • 3242795814 scopus 로고    scopus 로고
    • Intra-abdominal fat is a major determinant of the National Cholesterol Education Program Adult Treatment Panel III criteria for the metabolic syndrome
    • Carr DB, Utzschneider KM, Hull RL et al (2004) Intra-abdominal fat is a major determinant of the National Cholesterol Education Program Adult Treatment Panel III criteria for the metabolic syndrome. Diabetes 53: 2087-2094.
    • (2004) Diabetes , vol.53 , pp. 2087-2094
    • Carr, D.B.1    Utzschneider, K.M.2    Hull, R.L.3
  • 18
    • 12144287295 scopus 로고    scopus 로고
    • Evidence of increased visceral obesity and reduced physical fitness in healthy insulin-resistant first-degree relatives of type 2 diabetic patients
    • Nyholm B, Nielsen MF, Kristensen K et al (2004) Evidence of increased visceral obesity and reduced physical fitness in healthy insulin-resistant first-degree relatives of type 2 diabetic patients. Eur J Endocrinol 150: 207-214.
    • (2004) Eur J Endocrinol , vol.150 , pp. 207-214
    • Nyholm, B.1    Nielsen, M.F.2    Kristensen, K.3
  • 19
  • 20
    • 34249277021 scopus 로고    scopus 로고
    • Anorexia in chronic obstructive pulmonary disease: association to cachexia and hormonal derangement
    • Koehler F, Doehner W, Hoernig S, Witt C, Anker SD, John M (2007) Anorexia in chronic obstructive pulmonary disease: association to cachexia and hormonal derangement. Int J Cardiol 119: 83-89.
    • (2007) Int J Cardiol , vol.119 , pp. 83-89
    • Koehler, F.1    Doehner, W.2    Hoernig, S.3    Witt, C.4    Anker, S.D.5    John, M.6
  • 21
    • 30344482545 scopus 로고    scopus 로고
    • Body mass, fat-free body mass, and prognosis in patients with chronic obstructive pulmonary disease from a random population sample: findings from the Copenhagen City Heart Study
    • Vestbo J, Prescott E, Almdal T et al (2006) Body mass, fat-free body mass, and prognosis in patients with chronic obstructive pulmonary disease from a random population sample: findings from the Copenhagen City Heart Study. Am J Respir Crit Care Med 173: 79-83.
    • (2006) Am J Respir Crit Care Med , vol.173 , pp. 79-83
    • Vestbo, J.1    Prescott, E.2    Almdal, T.3
  • 22
    • 19944427849 scopus 로고    scopus 로고
    • The obesity paradox: Body mass index and outcomes in patients with heart failure
    • 47
    • Curtis JP, Selter JG, Wang Y et al. (2005) The obesity paradox: body mass index and outcomes in patients with heart failure. Arch Intern Med 165: 55-61. 47.
    • (2005) Arch Intern Med , vol.165 , pp. 55-61
    • Curtis, J.P.1    Selter, J.G.2    Wang, Y.3
  • 23
    • 77955329821 scopus 로고    scopus 로고
    • Metabolic syndrome is associated with increased risk of acute exacerbation of COPD: a preliminary study
    • Ulubay G, Ulasli SS, Sahin T, Erayman Z, Gùrsoy A (2010) Metabolic syndrome is associated with increased risk of acute exacerbation of COPD: a preliminary study. Endocrine 38: 76-82.
    • (2010) Endocrine , vol.38 , pp. 76-82
    • Ulubay, G.1    Ulasli, S.S.2    Sahin, T.3    Erayman, Z.4    Gùrsoy, A.5
  • 24
    • 33645975847 scopus 로고    scopus 로고
    • The effect of obesity on chronic respiratory diseases: pathophysiology and therapeutic strategies
    • Poulain M, Doucet M, Major GC et al (2006) The effect of obesity on chronic respiratory diseases: pathophysiology and therapeutic strategies. Can Med Ass J 174: 1293-1299.
    • (2006) Can Med Ass J , vol.174 , pp. 1293-1299
    • Poulain, M.1    Doucet, M.2    Major, G.C.3
  • 26
    • 56249083570 scopus 로고    scopus 로고
    • Prevalence and outcomes of diabetes, hypertension and cardiovascular disease in COPD
    • Mannino DM, Thorn D, Swensen A et al (2008) Prevalence and outcomes of diabetes, hypertension and cardiovascular disease in COPD. Eur Respir J 32: 962-969.
    • (2008) Eur Respir J , vol.32 , pp. 962-969
    • Mannino, D.M.1    Thorn, D.2    Swensen, A.3
  • 28
    • 41749120109 scopus 로고    scopus 로고
    • Extrapulmonary effects of chronic obstructive pulmonary disease on physical activity: a cross-sectional study
    • Watz H, Waschki B, Boehme C et al (2008) Extrapulmonary effects of chronic obstructive pulmonary disease on physical activity: a cross-sectional study. Am J Respir Crit Care Med 177: 743-751.
    • (2008) Am J Respir Crit Care Med , vol.177 , pp. 743-751
    • Watz, H.1    Waschki, B.2    Boehme, C.3
  • 29
    • 33847172367 scopus 로고    scopus 로고
    • Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease
    • Calverley PM, Anderson JA, Celli B et al (2007) Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease. N Engl J Med 356: 775-789.
    • (2007) N Engl J Med , vol.356 , pp. 775-789
    • Calverley, P.M.1    Anderson, J.A.2    Celli, B.3
  • 30
    • 37849011194 scopus 로고    scopus 로고
    • The prevention of chronic obstructive pulmonary disease exacerbations by salmeterol/fluticasone propionate or tiotropium bromide
    • Wedzicha JA, Calverley PM, Seemungal TA, Hagan G, Ansari Z, Stockley RA (2008) The prevention of chronic obstructive pulmonary disease exacerbations by salmeterol/fluticasone propionate or tiotropium bromide. Am J Respir Crit Care Med 177: 19-26.
    • (2008) Am J Respir Crit Care Med , vol.177 , pp. 19-26
    • Wedzicha, J.A.1    Calverley, P.M.2    Seemungal, T.A.3    Hagan, G.4    Ansari, Z.5    Stockley, R.A.6
  • 31
    • 78049430514 scopus 로고    scopus 로고
    • Inhaled corticosteroids and the risk of diabetes onset and progression
    • Suissa S, Kezouh A, Ernst P (2010) Inhaled corticosteroids and the risk of diabetes onset and progression. Am J Med 123(11): 1001-1006.
    • (2010) Am J Med , vol.123 , Issue.11 , pp. 1001-1006
    • Suissa, S.1    Kezouh, A.2    Ernst, P.3
  • 32
    • 34548277025 scopus 로고    scopus 로고
    • From COPD to chronic systemic inflammatory syndrome?
    • Fabbri LM, Rabe KF (2007) From COPD to chronic systemic inflammatory syndrome? Lancet 370: 797-799.
    • (2007) Lancet , vol.370 , pp. 797-799
    • Fabbri, L.M.1    Rabe, K.F.2
  • 34
    • 33747834015 scopus 로고    scopus 로고
    • Neff lecture: chronic obstructive pulmonary disease-a systemic disease
    • Agusti A, Thomas A (2006) Neff lecture: chronic obstructive pulmonary disease-a systemic disease. Proc Am Thorac Soc 3: 478-481.
    • (2006) Proc Am Thorac Soc , vol.3 , pp. 478-481
    • Agusti, A.1    Thomas, A.2
  • 35
    • 66749141807 scopus 로고    scopus 로고
    • Systemic manifestations and comorbidities of COPD
    • Barnes PJ, Celli B (2009) Systemic manifestations and comorbidities of COPD. Eur Respir J 33: 1165-1185.
    • (2009) Eur Respir J , vol.33 , pp. 1165-1185
    • Barnes, P.J.1    Celli, B.2
  • 36
    • 17644397560 scopus 로고    scopus 로고
    • Local and systemic inflammation in chronic obstructive pulmonary disease
    • Wouters EFM (2005) Local and systemic inflammation in chronic obstructive pulmonary disease. Proc Am Thor Soc 2: 26-33.
    • (2005) Proc Am Thor Soc , vol.2 , pp. 26-33
    • Wouters, E.F.M.1
  • 37
    • 0032956553 scopus 로고    scopus 로고
    • Predictive factors of hospitalization for acute exacerbation in a series of 64 patients with chronic obstructive pulmonary disease
    • Kessler R, Faller M, Fourgaut G, Mennecier M, Weitzenblum E (1999) Predictive factors of hospitalization for acute exacerbation in a series of 64 patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 159: 158-164.
    • (1999) Am J Respir Crit Care Med , vol.159 , pp. 158-164
    • Kessler, R.1    Faller, M.2    Fourgaut, G.3    Mennecier, M.4    Weitzenblum, E.5
  • 38
    • 77952487032 scopus 로고    scopus 로고
    • Systemic inflammation in chronic obstructive pulmonary disease: may adipose tissue play a role?
    • Ttkacova R (2010) Systemic inflammation in chronic obstructive pulmonary disease: may adipose tissue play a role? Rev Lit Future Perspect Mediat Inflamm 2010: 585989.
    • (2010) Rev Lit Future Perspect Mediat Inflamm , vol.2010 , pp. 585989
    • Ttkacova, R.1
  • 39
    • 0034890103 scopus 로고    scopus 로고
    • Physiological role of adipose tissue: white adipose tissue as an endocrine and secretory organ
    • Trayhurn P, Beattie JH (2001) Physiological role of adipose tissue: white adipose tissue as an endocrine and secretory organ. Proc Nutr Soc 60: 329-339.
    • (2001) Proc Nutr Soc , vol.60 , pp. 329-339
    • Trayhurn, P.1    Beattie, J.H.2
  • 40
    • 6944237757 scopus 로고    scopus 로고
    • Adipokines: inflammation and the pleiotropic role of white adipose tissue
    • Trayhurn P, Wood IS (2004) Adipokines: inflammation and the pleiotropic role of white adipose tissue. Br J Nutr 92: 347-355.
    • (2004) Br J Nutr , vol.92 , pp. 347-355
    • Trayhurn, P.1    Wood, I.S.2
  • 42
    • 0028931724 scopus 로고
    • Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance
    • Hotamisligil GS, Arner P, Caro JF, Atkinson RL, Spiegelman BM (1995) Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. J Clin Invest 95: 2409-2415.
    • (1995) J Clin Invest , vol.95 , pp. 2409-2415
    • Hotamisligil, G.S.1    Arner, P.2    Caro, J.F.3    Atkinson, R.L.4    Spiegelman, B.M.5
  • 43
    • 0035217644 scopus 로고    scopus 로고
    • Beta-adrenergic regulation of IL-6 release from adipose tissue: in vivo and in vitro studies
    • Mohamed-Ali V, Flower L, Sethi J et al (2001) Beta-adrenergic regulation of IL-6 release from adipose tissue: in vivo and in vitro studies. J Clin Endocrinol Metabol 86: 5864-5869.
    • (2001) J Clin Endocrinol Metabol , vol.86 , pp. 5864-5869
    • Mohamed-Ali, V.1    Flower, L.2    Sethi, J.3
  • 44
    • 0036614943 scopus 로고    scopus 로고
    • Opposite regulation of interleukin-8 and tumor necrosis factor-alpha by weight loss
    • Bruun JM, Pedersen SB, Kristensen K, Richelsen B (2002) Opposite regulation of interleukin-8 and tumor necrosis factor-alpha by weight loss. Obesity Res 10: 499-506.
    • (2002) Obesity Res , vol.10 , pp. 499-506
    • Bruun, J.M.1    Pedersen, S.B.2    Kristensen, K.3    Richelsen, B.4
  • 45
    • 34047119110 scopus 로고    scopus 로고
    • Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation
    • Hosogai H, Fukuhara A, Oshima K et al (2007) Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation. Diabetes 56: 901-911.
    • (2007) Diabetes , vol.56 , pp. 901-911
    • Hosogai, H.1    Fukuhara, A.2    Oshima, K.3
  • 46
    • 0036320934 scopus 로고    scopus 로고
    • Cellular adaptation to hypoxia: O2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression
    • Wenger RH (2002) Cellular adaptation to hypoxia: O2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression. FASEB J 16: 1151-1162.
    • (2002) FASEB J , vol.16 , pp. 1151-1162
    • Wenger, R.H.1
  • 47
    • 34547418119 scopus 로고    scopus 로고
    • Insulin resistance and inflammation: a further systemic complication of COPD
    • Bolton CE, Evans M, Ionescu AA et al (2007) Insulin resistance and inflammation: a further systemic complication of COPD. J COPD 4: 121-126.
    • (2007) J COPD , vol.4 , pp. 121-126
    • Bolton, C.E.1    Evans, M.2    Ionescu, A.A.3
  • 48
    • 78049381527 scopus 로고    scopus 로고
    • The impact of obesity on walking and cycling performance and response to pulmonary rehabilitation
    • Sava F, Laviolette L, Breton MJ, Bourbeau J, Maltais JF (2010) The impact of obesity on walking and cycling performance and response to pulmonary rehabilitation. BMC Pulm Med 10: 55.
    • (2010) BMC Pulm Med , vol.10 , pp. 55
    • Sava, F.1    Laviolette, L.2    Breton, M.J.3    Bourbeau, J.4    Maltais, J.F.5
  • 50
    • 77957705828 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease phenotypes: the future of COPD
    • Han MK, Agusti A, Calverley PM et al (2010) Chronic obstructive pulmonary disease phenotypes: the future of COPD. Am J Respir Crit Care Med 182(5): 598-604.
    • (2010) Am J Respir Crit Care Med , vol.182 , Issue.5 , pp. 598-604
    • Han, M.K.1    Agusti, A.2    Calverley, P.M.3


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