Single protein molecule detection by glass nanopores

ACS Nano

Volumn 7, Issue 5, 2013, Pages 4129-4134

  Li, Wenhong ^a   Bell, Nicholas A W ^a   Hernández Ainsa, Silvia ^a   Thacker, Vivek V ^a   Thackray, Alana M ^b   Bujdoso, Raymond ^b   Keyser, Ulrich F ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

diagnosis; nanocapillary; nanopores; prions; protein translocation; PrP; single molecule detection

Indexed keywords

NANOCAPILLARIES; PRIONS; PROTEIN TRANSLOCATION; PRP; SINGLE-MOLECULE DETECTION;

DIAGNOSIS; GLASS; MAMMALS; MOLECULES; NANOPORES;

PROTEINS;

GLASS; PROTEIN;

ANIMAL; ARTICLE; CATTLE; CHEMISTRY; HUMAN; MOLECULAR WEIGHT; NANOPORE; PROTEIN CONFORMATION; SIGNAL NOISE RATIO;

ANIMALS; CATTLE; GLASS; HUMANS; MOLECULAR WEIGHT; NANOPORES; PROTEIN CONFORMATION; PROTEINS; SIGNAL-TO-NOISE RATIO;

EID: 84878322580     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn4004567     Document Type: Article

References (33)

1. Bayley, H.; Martin, C. R. Resistive-Pulse Sensing: from Microbes to Molecules Chem. Rev. 2000, 100, 2575-2594
2. Kubitschek, H. E. Electronic Counting and Sizing of Bacteria Nature 1958, 182, 234-235
3. Zhang, Z.; Zhe, J.; Chandra, S.; Hu, J. An Electronic Pollen Detection Method Using Coulter Counting Principle Atmos. Environ. 2005, 39, 5446-5453
4. DeBlois, R. W.; Wesley, R. K. Sizes and Concentrations of Several Type C Oncornaviruses and Bacteriophage T2 by the Resistive-Pulse Technique J. Virol. 1977, 23, 227-233
5. Carbonaro, A.; Sohn, L. L. A Resistive-Pulse Sensor Chip for Multianalyte Immunoassays Lab. Chip 2005, 5, 1155-1160
6. Majd, S.; Yusko, E. C.; Billeh, Y. N.; Macrae, M. X.; Yang, J.; Mayer, M. Applications of Biological Pores in Nanomedicine, Sensing, and Nanoelectronics Curr. Opin. Biotechnol. 2010, 21, 439-476
7. Bell, N. A. W.; Engst, C. R.; Ablay, M.; Divitini, G.; Ducati, C.; Liedl, T.; Keyser, U. F. DNA Origami Nanopores Nano Lett. 2011, 12, 512-517
8. Stefureac, R.; Waldner, L.; Howard, P.; Lee, J. S. Nanopore Analysis of a Small 86-Residue Protein Small 2008, 4, 59-63
9. Oukhaled, G.; Mathé, J.; Biance, A. L.; Bacri, L.; Betton, J. M.; Lairez, D.; Pelta, J.; Auvray, L. Unfolding of Proteins and Long Transient Conformations Detected by Single Nanopore Recording Phys. Rev. Lett. 2007, 98, 158101
10. Pastoriza-Gallego, M.; Rabah, L.; Gibrat, G.; Thiebot, B.; van der Goot, F. G.; Auvray, L.; Betton, J.-M.; Pelta, J. Dynamics of Unfolded Protein Transport Through an Aerolysin Pore J. Am. Chem. Soc. 2011, 133, 2923-2931
11. Stefureac, R.; Long, Y.-t.; Kraatz, H.-B.; Howard, P.; Lee, J. S. Transport of α-Helical Peptides through α-Hemolysin and Aerolysin Pores Biochemistry 2006, 45, 9172-9179
12. Sutherland, T. C.; Long, Y.-T.; Stefureac, R.-I.; Bediako-Amoa, I.; Kraatz, H.-B.; Lee, J. S. Structure of Peptides Investigated by Nanopore Analysis Nano Lett. 2004, 4, 1273-1277
13. Madampage, C. A.; Andrievskaia, O.; Lee, J. S. Nanopore Detection of Antibody Prion Interactions Anal. Biochem. 2010, 396, 36-41
14. Wang, H.-Y.; Ying, Y.-L.; Li, Y.; Kraatz, H.-B.; Long, Y.-T. Nanopore Analysis of β-Amyloid Peptide Aggregation Transition Induced by Small Molecules Anal. Chem. 2011, 83, 1746-1752
15. Han, A.; Schurmann, G.; Mondin, G.; Bitterli, R. A.; Hegelbach, N. G.; de Rooij, N. F.; Staufer, U. Sensing Protein Molecules Using Nanofabricated Pores Appl. Phys. Lett. 2006, 88, 093901
16. Fologea, D.; Ledden, B.; McNabb, D. S.; Li, J. Electrical Characterization of Protein Molecules by a Solid-State Nanopore Appl. Phys. Lett. 2007, 91, 053901
17. Talaga, D. S.; Li, J. Single-Molecule Protein Unfolding in Solid State Nanopores J. Am. Chem. Soc. 2009, 131, 9287-9297
18. Han, A.; Creus, M.; Schürmann, G.; Linder, V.; Ward, T. R.; de Rooij, N. F.; Staufer, U. Label-Free Detection of Single Protein Molecules and Protein-Protein Interactions Using Synthetic Nanopores Anal. Chem. 2008, 80, 4651-4658
19. Sexton, L. T.; Mukaibo, H.; Katira, P.; Hess, H.; Sherrill, S. A.; Horne, L. P.; Martin, C. R. An Adsorption-Based Model for Pulse Duration in Resistive-Pulse Protein Sensing J. Am. Chem. Soc. 2010, 132, 6755-6763
20. Yusko, E. C.; Johnson, J. M.; Majd, S.; Prangkio, P.; Rollings, R. C.; Li, J.; Yang, J.; Mayer, M. Controlling Protein Translocation through Nanopores with Bio-Inspired Fluid Walls Nat. Nano 2011, 6, 253-260
21. Wei, R.; Gatterdam, V.; Wieneke, R.; Tampe, R.; Rant, U. Stochastic Sensing of Proteins with Receptor-Modified Solid-State Nanopores Nat. Nano 2012, 7, 257-263
22. Steinbock, L. J.; Otto, O.; Chimerel, C.; Gornall, J.; Keyser, U. F. Detecting DNA Folding with Nanocapillaries Nano Lett. 2010, 10, 2493-2497
23. Hernández-Ainsa, S.; Muus, C.; Bell, N. A. W.; Steinbock, L. J.; Thacker, V. V.; Keyser, U. F. Lipid-Coated Nanocapillaries for DNA Sensing Analyst 2013, 138, 104-106
24. Thacker, V. V.; Ghosal, S.; Hernández-Ainsa, S.; Bell, N. A. W.; Keyser, U. F. Studying DNA Translocation in Nanocapillaries Using Single Molecule Fluorescence Appl. Phys. Lett. 2012, 101, 223704
25. Steinbock, L. J.; Otto, O.; Skarstam, D. R.; Jahn, S.; Chimerel, C.; Gornall, J. L.; Keyser, U. F. Probing DNA with Micro- and Nanocapillaries and Optical Tweezers J. Phys.: Condens. Matter 2010, 22, 454113
26. C Kinetics PLoS One 2013, 8, e54982
27. Pedone, D.; Firnkes, M.; Rant, U. Data Analysis of Translocation Events in Nanopore Experiments Anal. Chem. 2009, 81, 9689-9694
28. Plesa, C.; Kowalczyk, S. W.; Zinsmeester, R.; Grosberg, A. Y.; Rabin, Y.; Dekker, C. Fast Translocation of Proteins through Solid State Nanopores Nano Lett. 2013, 13, 658-663
29. Firnkes, M.; Pedone, D.; Knezevic, J.; Döblinger, M.; Rant, U. Electrically Facilitated Translocations of Proteins through Silicon Nitride Nanopores: Conjoint and Competitive Action of Diffusion, Electrophoresis, and Electroosmosis Nano Lett. 2010, 10, 2162-2167
30. Umehara, S.; Pourmand, N.; Webb, C. D.; Davis, R. W.; Yasuda, K.; Karhanek, M. Current Rectification with Poly-l-Lysine-Coated Quartz Nanopipettes Nano Lett. 2006, 6, 2486-2492
31. Loeken, M. R.; Roth, T. F. Analysis of Maternal IgG Subpopulations which are Transported into the Chicken Oocyte Immunology 1983, 49, 21-28
32. Hornemann, S.; Korth, C.; Oesch, B.; Riek, R.; Wider, G.; Wüthrich, K.; Glockshuber, R. Recombinant Full-Length Murine Prion Protein, mPrP(23-231): Purification and Spectroscopic Characterization FEBS Lett. 1997, 413, 277-281
33. Wong, E.; Thackray, A. M.; Bujdoso, R. Copper Induces Increased Beta-Sheet Content in the Scrapie-Susceptible Ovine Prion Protein PrPVRQ Compared with the Resistant Allelic Variant PrPARR Biochem. J. 2004, 380, 273-282