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Volumn 35, Issue 5, 2013, Pages 470-478

Therapeutic applications of bone marrow-derived stem cells in ischemic stroke

Author keywords

Bone marrow; Clinical trial; Stem cells; Stroke; Transplantation

Indexed keywords

GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 6; TISSUE PLASMINOGEN ACTIVATOR;

EID: 84878318041     PISSN: 01616412     EISSN: 17431328     Source Type: Journal    
DOI: 10.1179/1743132813Y.0000000210     Document Type: Review
Times cited : (23)

References (83)
  • 2
    • 0034618861 scopus 로고    scopus 로고
    • Treatment of acute ischemic stroke
    • Brott T, Bogousslavsky J. Treatment of acute ischemic stroke. N Engl J Med. 2000;343:710-22.
    • (2000) N Engl J Med. , vol.343 , pp. 710-722
    • Brott, T.1    Bogousslavsky, J.2
  • 3
    • 34247844511 scopus 로고    scopus 로고
    • Guidelines for the early management of adults with ischemic stroke
    • A guideline from the American Heart Association/American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: The American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists
    • Adams HP, Jr, del Zoppo G, Alberts MJ, Bhatt DL, Brass L, Furlan A, et al. Guidelines for the early management of adults with ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: the American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists. Stroke. 2007;38:1655-711.
    • (2007) Stroke. , vol.38 , pp. 1655-1711
    • Adams Jr., H.P.1    del Zoppo, G.2    Alberts, M.J.3    Bhatt, D.L.4    Brass, L.5    Furlan, A.6
  • 4
    • 0033485522 scopus 로고    scopus 로고
    • Recombinant tissue-type plasminogen activator (Alteplase) for ischemic stroke 3 to 5 hours after symptom onset. The ATLANTIS Study: A randomized controlled trial. Alteplase Thrombolysis for Acute Noninterventional Therapy in Ischemic Stroke
    • Clark WM, Wissman S, Albers GW, Jhamandas JH, Madden KP, Hamilton S. Recombinant tissue-type plasminogen activator (Alteplase) for ischemic stroke 3 to 5 hours after symptom onset. The ATLANTIS Study: a randomized controlled trial. Alteplase Thrombolysis for Acute Noninterventional Therapy in Ischemic Stroke. JAMA. 1999;282:2019-26.
    • (1999) JAMA. , vol.282 , pp. 2019-2026
    • Clark, W.M.1    Wissman, S.2    Albers, G.W.3    Jhamandas, J.H.4    Madden, K.P.5    Hamilton, S.6
  • 5
    • 34848883164 scopus 로고    scopus 로고
    • Randomized trial of intraarterial infusion of urokinase within 6 hours of middle cerebral artery stroke: The middle cerebral artery embolism local fibrinolytic intervention trial (MELT) Japan
    • Ogawa A, Mori E, Minematsu K, Taki W, Takahashi A, Nemoto S, et al. Randomized trial of intraarterial infusion of urokinase within 6 hours of middle cerebral artery stroke: the middle cerebral artery embolism local fibrinolytic intervention trial (MELT) Japan. Stroke. 2007;38:2633-9.
    • (2007) Stroke. , vol.38 , pp. 2633-2639
    • Ogawa, A.1    Mori, E.2    Minematsu, K.3    Taki, W.4    Takahashi, A.5    Nemoto, S.6
  • 7
    • 19544376511 scopus 로고    scopus 로고
    • Neuroprotection for ischemic stroke: Two decades of success and failure
    • Cheng YD, Al-Khoury L, Zivin JA. Neuroprotection for ischemic stroke: two decades of success and failure. NeuroRx. 2004;1:36-45.
    • (2004) NeuroRx. , vol.1 , pp. 36-45
    • Cheng, Y.D.1    Al-Khoury, L.2    Zivin, J.A.3
  • 8
    • 67349239035 scopus 로고    scopus 로고
    • Regeneration of the ischemic brain by engineered stem cells: Fuelling endogenous repair processes
    • van Velthoven CT, Kavelaars A, van Bel F, Heijnen CJ. Regeneration of the ischemic brain by engineered stem cells: fuelling endogenous repair processes. Brain Res Rev. 2009;61:1-13.
    • (2009) Brain Res Rev. , vol.61 , pp. 1-13
    • van Velthoven, C.T.1    Kavelaars, A.2    van Bel, F.3    Heijnen, C.J.4
  • 9
    • 77956638921 scopus 로고    scopus 로고
    • A long-term follow-up study of intravenous autologous mesenchymal stem cell transplantation in patients with ischemic stroke
    • Lee JS, Hong JM, Moon GJ, Lee PH, Ahn YH, Bang OY. A long-term follow-up study of intravenous autologous mesenchymal stem cell transplantation in patients with ischemic stroke. Stem Cells. 2010;28:1099-106.
    • (2010) Stem Cells. , vol.28 , pp. 1099-1106
    • Lee, J.S.1    Hong, J.M.2    Moon, G.J.3    Lee, P.H.4    Ahn, Y.H.5    Bang, O.Y.6
  • 10
    • 85042012606 scopus 로고    scopus 로고
    • Autologous mesenchymal stem cell transplantation in stroke patients
    • author reply 654-5
    • de Keyser J. Autologous mesenchymal stem cell transplantation in stroke patients. Ann Neurol. 2005;58:653-4; author reply 654-5.
    • (2005) Ann Neurol. , vol.58 , pp. 653-654
    • de Keyser, J.1
  • 11
    • 20444419744 scopus 로고    scopus 로고
    • Autologous mesenchymal stem cell transplantation in stroke patients
    • Bang OY, Lee JS, Lee PH, Lee G. Autologous mesenchymal stem cell transplantation in stroke patients. Ann Neurol. 2005;57:874-82.
    • (2005) Ann Neurol. , vol.57 , pp. 874-882
    • Bang, O.Y.1    Lee, J.S.2    Lee, P.H.3    Lee, G.4
  • 12
    • 72749121996 scopus 로고    scopus 로고
    • Optimizing the success of cell transplantation therapy for stroke
    • Bliss TM, Andres RH, Steinberg GK. Optimizing the success of cell transplantation therapy for stroke. Neurobiol Dis. 2010;37:275-83.
    • (2010) Neurobiol Dis. , vol.37 , pp. 275-283
    • Bliss, T.M.1    Andres, R.H.2    Steinberg, G.K.3
  • 13
    • 20444419744 scopus 로고    scopus 로고
    • Autologous mesenchymal stem cell transplantation in stroke patients
    • Bang OY, Lee JS, Lee PH, Lee G. Autologous mesenchymal stem cell transplantation in stroke patients. Ann Neurol. 2005;57:874-82.
    • (2005) Ann Neurol. , vol.57 , pp. 874-882
    • Bang, O.Y.1    Lee, J.S.2    Lee, P.H.3    Lee, G.4
  • 14
    • 57049089034 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stem cells for the treatment of ischemic stroke
    • Dharmasaroja P. Bone marrow-derived mesenchymal stem cells for the treatment of ischemic stroke. J Clin Neurosci. 2009;16:12-20.
    • (2009) J Clin Neurosci. , vol.16 , pp. 12-20
    • Dharmasaroja, P.1
  • 17
    • 72749121996 scopus 로고    scopus 로고
    • Optimizing the success of cell transplantation therapy for stroke
    • Bliss TM, Andres RH, Steinberg GK. Optimizing the success of cell transplantation therapy for stroke. Neurobiol Dis. 2010;37:275-83.
    • (2010) Neurobiol Dis. , vol.37 , pp. 275-283
    • Bliss, T.M.1    Andres, R.H.2    Steinberg, G.K.3
  • 18
    • 77949470463 scopus 로고    scopus 로고
    • Intravenously administered BMSCs reduce neuronal apoptosis and promote neuronal proliferation through the release of VEGF after stroke in rats
    • Deng YB, Ye WB, Hu ZZ, Yan Y, Wang Y, Takon BF, et al. Intravenously administered BMSCs reduce neuronal apoptosis and promote neuronal proliferation through the release of VEGF after stroke in rats. Neurol Res. 2010;32:148-56.
    • (2010) Neurol Res. , vol.32 , pp. 148-156
    • Deng, Y.B.1    Ye, W.B.2    Hu, Z.Z.3    Yan, Y.4    Wang, Y.5    Takon, B.F.6
  • 19
    • 79957812970 scopus 로고    scopus 로고
    • Transfection of Noggin in bone marrow stromal cells (BMSCs) enhances BMSC-induced functional outcome after stroke in rats
    • Chen C, Cheng Y, Chen J. Transfection of Noggin in bone marrow stromal cells (BMSCs) enhances BMSC-induced functional outcome after stroke in rats. J Neurosci Res. 2011;89:1194-202.
    • (2011) J Neurosci Res. , vol.89 , pp. 1194-1202
    • Chen, C.1    Cheng, Y.2    Chen, J.3
  • 20
    • 1942535132 scopus 로고    scopus 로고
    • A therapeutic window for intravenous administration of autologous bone marrow after cerebral ischemia in adult rats
    • Iihoshi S, Honmou O, Houkin K, Hashi K, Kocsis JD. A therapeutic window for intravenous administration of autologous bone marrow after cerebral ischemia in adult rats. Brain Res. 2004;1007:1-9.
    • (2004) Brain Res. , vol.1007 , pp. 1-9
    • Iihoshi, S.1    Honmou, O.2    Houkin, K.3    Hashi, K.4    Kocsis, J.D.5
  • 21
    • 29744441582 scopus 로고    scopus 로고
    • Intracarotid transplantation of bone marrow stromal cells increases axon-myelin remodeling after stroke
    • Shen LH, Li Y, Chen J, Zhang J, Vanguri P, Borneman J, et al. Intracarotid transplantation of bone marrow stromal cells increases axon-myelin remodeling after stroke. Neuroscience. 2006;137:393-9.
    • (2006) Neuroscience. , vol.137 , pp. 393-399
    • Shen, L.H.1    Li, Y.2    Chen, J.3    Zhang, J.4    Vanguri, P.5    Borneman, J.6
  • 22
    • 2342566505 scopus 로고    scopus 로고
    • Bone marrow grafts restore cerebral blood flow and blood brain barrier in stroke rats
    • Borlongan CV, Lind JG, Dillon-Carter O, Yu G, Hadman M, Cheng C, et al. Bone marrow grafts restore cerebral blood flow and blood brain barrier in stroke rats. Brain Res. 2004;1010:108-16.
    • (2004) Brain Res. , vol.1010 , pp. 108-116
    • Borlongan, C.V.1    Lind, J.G.2    Dillon-Carter, O.3    Yu, G.4    Hadman, M.5    Cheng, C.6
  • 23
    • 15944397267 scopus 로고    scopus 로고
    • Comparison of ischemia-directed migration of neural precursor cells after intrastriatal, intraventricular, or intravenous transplantation in the rat
    • Jin K, Sun Y, Xie L, Mao XO, Childs J, Peel A, et al. Comparison of ischemia-directed migration of neural precursor cells after intrastriatal, intraventricular, or intravenous transplantation in the rat. Neurobiol Dis. 2005;18:366-74.
    • (2005) Neurobiol Dis. , vol.18 , pp. 366-374
    • Jin, K.1    Sun, Y.2    Xie, L.3    Mao, X.O.4    Childs, J.5    Peel, A.6
  • 24
    • 0029128101 scopus 로고
    • Implantable biohybrid artificial organs
    • Colton CK. Implantable biohybrid artificial organs. Cell Transplant. 1995;4:415-36.
    • (1995) Cell Transplant. , vol.4 , pp. 415-436
    • Colton, C.K.1
  • 25
    • 0027595948 scopus 로고
    • Tissue engineering
    • Langer R, Vacanti JP. Tissue engineering. Science. 1993;260:920-6.
    • (1993) Science. , vol.260 , pp. 920-926
    • Langer, R.1    Vacanti, J.P.2
  • 26
    • 33645504776 scopus 로고    scopus 로고
    • Nano neuro knitting: Peptide nanofiber scaffold for brain repair and axon regeneration with functional return of vision
    • Ellis-Behnke RG, Liang YX, You SW, Tay DK, Zhang S, So KF, et al. Nano neuro knitting: peptide nanofiber scaffold for brain repair and axon regeneration with functional return of vision. Proc Natl Acad Sci USA. 2006;103:5054-9.
    • (2006) Proc Natl Acad Sci USA. , vol.103 , pp. 5054-5059
    • Ellis-Behnke, R.G.1    Liang, Y.X.2    You, S.W.3    Tay, D.K.4    Zhang, S.5    So, K.F.6
  • 27
    • 26444442336 scopus 로고    scopus 로고
    • The repair of brain lesion by implantation of hyaluronic acid hydrogels modified with laminin
    • Hou S, Xu Q, Tian W, Cui F, Cai Q, Ma J, et al. The repair of brain lesion by implantation of hyaluronic acid hydrogels modified with laminin. J Neurosci Methods. 2005;148:60-70.
    • (2005) J Neurosci Methods. , vol.148 , pp. 60-70
    • Hou, S.1    Xu, Q.2    Tian, W.3    Cui, F.4    Cai, Q.5    Ma, J.6
  • 28
    • 33646809089 scopus 로고    scopus 로고
    • Implantation of a new porous gelatin-siloxane hybrid into a brain lesion as a potential scaffold for tissue regeneration
    • Deguchi K, Tsuru K, Hayashi T, Takaishi M, Nagahara M, Nagotani S, et al. Implantation of a new porous gelatin-siloxane hybrid into a brain lesion as a potential scaffold for tissue regeneration. J Cereb Blood Flow Metab. 2006;26:1263-73.
    • (2006) J Cereb Blood Flow Metab. , vol.26 , pp. 1263-1273
    • Deguchi, K.1    Tsuru, K.2    Hayashi, T.3    Takaishi, M.4    Nagahara, M.5    Nagotani, S.6
  • 29
    • 0037022618 scopus 로고    scopus 로고
    • Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells
    • Teng YD, Lavik EB, Qu X, Park KI, Ourednik J, Zurakowski D, et al. Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells. Proc Natl Acad Sci USA. 2002;99:3024-9.
    • (2002) Proc Natl Acad Sci USA. , vol.99 , pp. 3024-3029
    • Teng, Y.D.1    Lavik, E.B.2    Qu, X.3    Park, K.I.4    Ourednik, J.5    Zurakowski, D.6
  • 30
    • 0035998732 scopus 로고    scopus 로고
    • Fibronectin promotes survival and migration of primary neural stem cells transplanted into the traumatically injured mouse brain
    • Tate MC, Shear DA, Hoffman SW, Stein DG, Archer DR, LaPlaca MC. Fibronectin promotes survival and migration of primary neural stem cells transplanted into the traumatically injured mouse brain. Cell Transplant. 2002;11:283-95.
    • (2002) Cell Transplant. , vol.11 , pp. 283-295
    • Tate, M.C.1    Shear, D.A.2    Hoffman, S.W.3    Stein, D.G.4    Archer, D.R.5    LaPlaca, M.C.6
  • 31
    • 77649276002 scopus 로고    scopus 로고
    • Transplantation of human neural precursor cells in Matrigel scaffolding improves outcome from focal cerebral ischemia after delayed postischemic treatment in rats
    • Jin K, Mao X, Xie L, Galvan V, Lai B, Wang Y, et al. Transplantation of human neural precursor cells in Matrigel scaffolding improves outcome from focal cerebral ischemia after delayed postischemic treatment in rats. J Cereb Blood Flow Metab. 2010;30:534-44.
    • (2010) J Cereb Blood Flow Metab. , vol.30 , pp. 534-544
    • Jin, K.1    Mao, X.2    Xie, L.3    Galvan, V.4    Lai, B.5    Wang, Y.6
  • 33
    • 65549165864 scopus 로고    scopus 로고
    • Challenges and possibilities of intravascular cell therapy in stroke
    • Hicks A, Jolkkonen J. Challenges and possibilities of intravascular cell therapy in stroke. Acta Neurobiol Exp (Wars). 2009;69:1-11.
    • (2009) Acta Neurobiol Exp (Wars). , vol.69 , pp. 1-11
    • Hicks, A.1    Jolkkonen, J.2
  • 34
    • 0035167706 scopus 로고    scopus 로고
    • Intravenous administration of human umbilical cord blood reduces behavioral deficits after stroke in rats
    • Chen J, Sanberg PR, Li Y, Wang L, Lu M, Willing AE, et al. Intravenous administration of human umbilical cord blood reduces behavioral deficits after stroke in rats. Stroke. 2001;32:2682-8.
    • (2001) Stroke. , vol.32 , pp. 2682-2688
    • Chen, J.1    Sanberg, P.R.2    Li, Y.3    Wang, L.4    Lu, M.5    Willing, A.E.6
  • 35
    • 66249096305 scopus 로고    scopus 로고
    • Pulmonary passage is a major obstacle for intravenous stem cell delivery: The pulmonary first-pass effect
    • Fischer UM, Harting MT, Jimenez F, Monzon-Posadas WO, Xue H, Savitz SI, et al. Pulmonary passage is a major obstacle for intravenous stem cell delivery: the pulmonary first-pass effect. Stem Cells Dev. 2009;18:683-92.
    • (2009) Stem Cells Dev. , vol.18 , pp. 683-692
    • Fischer, U.M.1    Harting, M.T.2    Jimenez, F.3    Monzon-Posadas, W.O.4    Xue, H.5    Savitz, S.I.6
  • 36
    • 4744358048 scopus 로고    scopus 로고
    • Central nervous system entry of peripherally injected umbilical cord blood cells is not required for neuroprotection in stroke
    • Borlongan CV, Hadman M, Sanberg CD, Sanberg PR. Central nervous system entry of peripherally injected umbilical cord blood cells is not required for neuroprotection in stroke. Stroke. 2004;35:2385-9.
    • (2004) Stroke. , vol.35 , pp. 2385-2389
    • Borlongan, C.V.1    Hadman, M.2    Sanberg, C.D.3    Sanberg, P.R.4
  • 37
    • 0037183512 scopus 로고    scopus 로고
    • Human marrow stromal cell therapy for stroke in rat: Neurotrophins and functional recovery
    • Li Y, Chen J, Chen XG, Wang L, Gautam SC, Xu YX, et al. Human marrow stromal cell therapy for stroke in rat: neurotrophins and functional recovery. Neurology. 2002;59:514-23.
    • (2002) Neurology. , vol.59 , pp. 514-523
    • Li, Y.1    Chen, J.2    Chen, X.G.3    Wang, L.4    Gautam, S.C.5    Xu, Y.X.6
  • 38
    • 27844472057 scopus 로고    scopus 로고
    • Combined treatment of vascular endothelial growth factor and human neural stem cells in experimental focal cerebral ischemia
    • Chu K, Park KI, Lee ST, Jung KH, Ko SY, Kang L, et al. Combined treatment of vascular endothelial growth factor and human neural stem cells in experimental focal cerebral ischemia. Neurosci Res. 2005;53:384-90.
    • (2005) Neurosci Res. , vol.53 , pp. 384-390
    • Chu, K.1    Park, K.I.2    Lee, S.T.3    Jung, K.H.4    Ko, S.Y.5    Kang, L.6
  • 39
    • 22444450988 scopus 로고    scopus 로고
    • Neurosphere-derived multipotent precursors promote neuroprotection by an immunomodulatory mechanism
    • Pluchino S, Zanotti L, Rossi B, Brambilla E, Ottoboni L, Salani G, et al. Neurosphere-derived multipotent precursors promote neuroprotection by an immunomodulatory mechanism. Nature. 2005;436:266-71.
    • (2005) Nature. , vol.436 , pp. 266-271
    • Pluchino, S.1    Zanotti, L.2    Rossi, B.3    Brambilla, E.4    Ottoboni, L.5    Salani, G.6
  • 40
    • 33845783926 scopus 로고    scopus 로고
    • Therapeutic benefit of bone marrow stromal cells administered 1 month after stroke
    • Shen LH, Li Y, Chen J, Zacharek A, Gao Q, Kapke A, et al. Therapeutic benefit of bone marrow stromal cells administered 1 month after stroke. J Cereb Blood Flow Metab. 2007;27:6-13.
    • (2007) J Cereb Blood Flow Metab. , vol.27 , pp. 6-13
    • Shen, L.H.1    Li, Y.2    Chen, J.3    Zacharek, A.4    Gao, Q.5    Kapke, A.6
  • 41
    • 44449176192 scopus 로고    scopus 로고
    • Dual-modality monitoring of targeted intraarterial delivery of mesenchymal stem cells after transient ischemia
    • Walczak P, Zhang J, Gilad AA, Kedziorek DA, Ruiz-Cabello J, Young RG, et al. Dual-modality monitoring of targeted intraarterial delivery of mesenchymal stem cells after transient ischemia. Stroke. 2008;39:1569-74.
    • (2008) Stroke. , vol.39 , pp. 1569-1574
    • Walczak, P.1    Zhang, J.2    Gilad, A.A.3    Kedziorek, D.A.4    Ruiz-Cabello, J.5    Young, R.G.6
  • 42
    • 33748060984 scopus 로고    scopus 로고
    • Imaging-guided acute ischemic stroke therapy: From 'time is brain' to 'physiology is brain'
    • Gonzalez RG. Imaging-guided acute ischemic stroke therapy: from 'time is brain' to 'physiology is brain'. AJNR Am J Neuroradiol. 2006;27:728-35.
    • (2006) AJNR Am J Neuroradiol. , vol.27 , pp. 728-735
    • Gonzalez, R.G.1
  • 43
    • 0031033912 scopus 로고    scopus 로고
    • Progression of ischaemic stroke and excitotoxic aminoacids
    • Castillo J, Davalos A, Noya M. Progression of ischaemic stroke and excitotoxic aminoacids. Lancet. 1997;349:79-83.
    • (1997) Lancet. , vol.349 , pp. 79-83
    • Castillo, J.1    Davalos, A.2    Noya, M.3
  • 44
    • 0029993974 scopus 로고    scopus 로고
    • Neuroexcitatory amino acids and their relation to infarct size and neurological deficit in ischemic stroke
    • Castillo J, Davalos A, Naveiro J, Noya M. Neuroexcitatory amino acids and their relation to infarct size and neurological deficit in ischemic stroke. Stroke. 1996;27:1060-5.
    • (1996) Stroke. , vol.27 , pp. 1060-1065
    • Castillo, J.1    Davalos, A.2    Naveiro, J.3    Noya, M.4
  • 45
    • 3042793193 scopus 로고    scopus 로고
    • Dynamics of free radical processes in acute ischemic stroke: Influence on neurological status and outcome
    • Alexandrova M, Bochev P, Markova V, Bechev B, Popova M, Danovska M, et al. Dynamics of free radical processes in acute ischemic stroke: influence on neurological status and outcome. J Clin Neurosci. 2004;11:501-6.
    • (2004) J Clin Neurosci. , vol.11 , pp. 501-506
    • Alexandrova, M.1    Bochev, P.2    Markova, V.3    Bechev, B.4    Popova, M.5    Danovska, M.6
  • 46
    • 71049180369 scopus 로고    scopus 로고
    • Inflammatory mechanisms in ischemic stroke: Therapeutic approaches
    • Lakhan SE, Kirchgessner A, Hofer M. Inflammatory mechanisms in ischemic stroke: therapeutic approaches. J Transl Med. 2009;7:97.
    • (2009) J Transl Med. , vol.7 , pp. 97
    • Lakhan, S.E.1    Kirchgessner, A.2    Hofer, M.3
  • 47
    • 0344417098 scopus 로고    scopus 로고
    • Perfusion measurements of the brain: Using dynamic CT for the quantitative assessment of cerebral ischemia in acute stroke
    • Klotz E, Konig M. Perfusion measurements of the brain: using dynamic CT for the quantitative assessment of cerebral ischemia in acute stroke. Eur J Radiol. 1999;30:170-84.
    • (1999) Eur J Radiol. , vol.30 , pp. 170-184
    • Klotz, E.1    Konig, M.2
  • 48
    • 33845480805 scopus 로고    scopus 로고
    • Granulocyte-colony-stimulating factor mobilizes bone marrow stem cells in patients with subacute ischemic stroke: The Stem cell Trial of recovery EnhanceMent after Stroke (STEMS) pilot randomized, controlled trial (ISRCTN 16784092)
    • Sprigg N, Bath PM, Zhao L, Willmot MR, Gray LJ, Walker MF, et al. Granulocyte-colony-stimulating factor mobilizes bone marrow stem cells in patients with subacute ischemic stroke: the Stem cell Trial of recovery EnhanceMent after Stroke (STEMS) pilot randomized, controlled trial (ISRCTN 16784092). Stroke. 2006;37:2979-83.
    • (2006) Stroke. , vol.37 , pp. 2979-2983
    • Sprigg, N.1    Bath, P.M.2    Zhao, L.3    Willmot, M.R.4    Gray, L.J.5    Walker, M.F.6
  • 49
    • 33645567790 scopus 로고    scopus 로고
    • Granulocyte colonystimulating factor for acute ischemic stroke: A randomized controlled trial
    • Shyu WC, Lin SZ, Lee CC, Liu DD, Li H. Granulocyte colonystimulating factor for acute ischemic stroke: a randomized controlled trial. CMAJ. 2006;174:927-33.
    • (2006) CMAJ. , vol.174 , pp. 927-933
    • Shyu, W.C.1    Lin, S.Z.2    Lee, C.C.3    Liu, D.D.4    Li, H.5
  • 50
    • 78650860359 scopus 로고    scopus 로고
    • Cell number and timing of transplantation determine survival of human neural stem cell grafts in stroke-damaged rat brain
    • Darsalia V, Allison SJ, Cusulin C, Monni E, Kuzdas D, Kallur T, et al. Cell number and timing of transplantation determine survival of human neural stem cell grafts in stroke-damaged rat brain. J Cereb Blood Flow Metab. 2011;31:235-42.
    • (2011) J Cereb Blood Flow Metab. , vol.31 , pp. 235-242
    • Darsalia, V.1    Allison, S.J.2    Cusulin, C.3    Monni, E.4    Kuzdas, D.5    Kallur, T.6
  • 51
    • 0035881367 scopus 로고    scopus 로고
    • Therapeutic benefit of intracerebral transplantation of bone marrow stromal cells after cerebral ischemia in rats
    • Chen J, Li Y, Wang L, Lu M, Zhang X, Chopp M. Therapeutic benefit of intracerebral transplantation of bone marrow stromal cells after cerebral ischemia in rats. J Neurol Sci. 2001;189:49-57.
    • (2001) J Neurol Sci. , vol.189 , pp. 49-57
    • Chen, J.1    Li, Y.2    Wang, L.3    Lu, M.4    Zhang, X.5    Chopp, M.6
  • 52
    • 0036715222 scopus 로고    scopus 로고
    • Effects of implantation site of stem cell grafts on behavioral recovery from stroke damage
    • Modo M, Stroemer RP, Tang E, Patel S, Hodges H. Effects of implantation site of stem cell grafts on behavioral recovery from stroke damage. Stroke. 2002;33:2270-8.
    • (2002) Stroke. , vol.33 , pp. 2270-2278
    • Modo, M.1    Stroemer, R.P.2    Tang, E.3    Patel, S.4    Hodges, H.5
  • 53
    • 0032845121 scopus 로고    scopus 로고
    • Ischemic cell death in brain neurons
    • Lipton P. Ischemic cell death in brain neurons. Physiol Rev. 1999;79:1431-568.
    • (1999) Physiol Rev. , vol.79 , pp. 1431-1568
    • Lipton, P.1
  • 55
    • 70449088920 scopus 로고    scopus 로고
    • The effect of mean pore size on cell attachment, proliferation and migration in collagenglycosaminoglycan scaffolds for bone tissue engineering
    • Murphy CM, Haugh MG, O'Brien FJ. The effect of mean pore size on cell attachment, proliferation and migration in collagenglycosaminoglycan scaffolds for bone tissue engineering. Biomaterials. 2010;31:461-6.
    • (2010) Biomaterials. , vol.31 , pp. 461-466
    • Murphy, C.M.1    Haugh, M.G.2    O'Brien, F.J.3
  • 56
    • 57049089034 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stem cells for the treatment of ischemic stroke
    • Dharmasaroja P. Bone marrow-derived mesenchymal stem cells for the treatment of ischemic stroke. J Clin Neurosci. 2009;16:12-20.
    • (2009) J Clin Neurosci. , vol.16 , pp. 12-20
    • Dharmasaroja, P.1
  • 57
    • 20444419744 scopus 로고    scopus 로고
    • Autologous mesenchymal stem cell transplantation in stroke patients
    • Bang OY, Lee JS, Lee PH, Lee G. Autologous mesenchymal stem cell transplantation in stroke patients. Ann Neurol. 2005;57:874-82.
    • (2005) Ann Neurol. , vol.57 , pp. 874-882
    • Bang, O.Y.1    Lee, J.S.2    Lee, P.H.3    Lee, G.4
  • 59
  • 60
    • 84930486490 scopus 로고    scopus 로고
    • Intra-arterial infusion of autologous bone marrow mononuclear cells in patients with moderate to severe middle cerebral artery acute ischemic stroke
    • Friedrich MA, Martins MP, Araujo MD, Klamt C, Vedolin L, Garicochea B, et al. Intra-arterial infusion of autologous bone marrow mononuclear cells in patients with moderate to severe middle cerebral artery acute ischemic stroke. Cell Transplant. 2012;21(Suppl 1):S13-21.
    • (2012) Cell Transplant. , vol.21 , Issue.SUPPL. 1
    • Friedrich, M.A.1    Martins, M.P.2    Araujo, M.D.3    Klamt, C.4    Vedolin, L.5    Garicochea, B.6
  • 62
    • 0034839778 scopus 로고    scopus 로고
    • Viability thresholds of ischemic penumbra of hyperacute stroke defined by perfusion-weighted MRI and apparent diffusion coefficient
    • Rohl L, Ostergaard L, Simonsen CZ, Vestergaard-Poulsen P, Andersen G, Sakoh M, et al. Viability thresholds of ischemic penumbra of hyperacute stroke defined by perfusion-weighted MRI and apparent diffusion coefficient. Stroke. 2001;32:1140-6.
    • (2001) Stroke. , vol.32 , pp. 1140-1146
    • Rohl, L.1    Ostergaard, L.2    Simonsen, C.Z.3    Vestergaard-Poulsen, P.4    Andersen, G.5    Sakoh, M.6
  • 63
    • 0034839640 scopus 로고    scopus 로고
    • Usefulness of magnetic resonance-derived quantitative measurements of cerebral blood flow and volume in prediction of infarct growth in hyperacute stroke
    • Grandin CB, Duprez TP, Smith AM, Mataigne F, Peeters A, Oppenheim C, et al. Usefulness of magnetic resonance-derived quantitative measurements of cerebral blood flow and volume in prediction of infarct growth in hyperacute stroke. Stroke. 2001;32:1147-53.
    • (2001) Stroke. , vol.32 , pp. 1147-1153
    • Grandin, C.B.1    Duprez, T.P.2    Smith, A.M.3    Mataigne, F.4    Peeters, A.5    Oppenheim, C.6
  • 64
    • 56149120390 scopus 로고    scopus 로고
    • Patients with acute stroke treated with intravenous tPA 3-6 hours after stroke onset: Correlations between MR angiography findings and perfusion-and diffusion-weighted imaging in the DEFUSE study
    • Marks MP, Olivot JM, Kemp S, Lansberg MG, Bammer R, Wechsler LR, et al. Patients with acute stroke treated with intravenous tPA 3-6 hours after stroke onset: correlations between MR angiography findings and perfusion-and diffusion-weighted imaging in the DEFUSE study. Radiology. 2008;249:614-23.
    • (2008) Radiology. , vol.249 , pp. 614-623
    • Marks, M.P.1    Olivot, J.M.2    Kemp, S.3    Lansberg, M.G.4    Bammer, R.5    Wechsler, L.R.6
  • 65
    • 0036151637 scopus 로고    scopus 로고
    • MR imaging in acute stroke: Diffusion-weighted and perfusion imaging parameters for predicting infarct size
    • Wittsack HJ, Ritzl A, Fink GR, Wenserski F, Siebler M, Seitz RJ, et al. MR imaging in acute stroke: diffusion-weighted and perfusion imaging parameters for predicting infarct size. Radiology. 2002;222:397-403.
    • (2002) Radiology. , vol.222 , pp. 397-403
    • Wittsack, H.J.1    Ritzl, A.2    Fink, G.R.3    Wenserski, F.4    Siebler, M.5    Seitz, R.J.6
  • 66
    • 84867539057 scopus 로고    scopus 로고
    • Tracking stem cells for cellular therapy in stroke
    • Manley NC, Steinberg GK. Tracking stem cells for cellular therapy in stroke. Curr Pharm Des. 2012;18:3685-93.
    • (2012) Curr Pharm Des. , vol.18 , pp. 3685-3693
    • Manley, N.C.1    Steinberg, G.K.2
  • 67
    • 79961208735 scopus 로고    scopus 로고
    • Stem cell research in stroke: How far from the clinic?
    • Lindvall O, Kokaia Z. Stem cell research in stroke: how far from the clinic? Stroke. 2011;42:2369-75.
    • (2011) Stroke. , vol.42 , pp. 2369-2375
    • Lindvall, O.1    Kokaia, Z.2
  • 68
    • 20444429578 scopus 로고    scopus 로고
    • Adult mesenchymal stem cells: Characterization, differentiation, and application in cell and gene therapy
    • Baksh D, Song L, Tuan RS. Adult mesenchymal stem cells: characterization, differentiation, and application in cell and gene therapy. J Cell Mol Med. 2004;8:301-16.
    • (2004) J Cell Mol Med. , vol.8 , pp. 301-316
    • Baksh, D.1    Song, L.2    Tuan, R.S.3
  • 69
    • 2442425347 scopus 로고    scopus 로고
    • Intracerebral xenotransplantation of GFP mouse bone marrow stromal cells in intact and stroke rat brain: Graft survival and immunologic response
    • Irons H, Lind JG, Wakade CG, Yu G, Hadman M, Carroll J, et al. Intracerebral xenotransplantation of GFP mouse bone marrow stromal cells in intact and stroke rat brain: graft survival and immunologic response. Cell Transplant. 2004;13:283-94.
    • (2004) Cell Transplant. , vol.13 , pp. 283-294
    • Irons, H.1    Lind, J.G.2    Wakade, C.G.3    Yu, G.4    Hadman, M.5    Carroll, J.6
  • 70
    • 77958138738 scopus 로고    scopus 로고
    • Transplanted bone marrow stem cells relocate to infarct penumbra and co-express endogenous proliferative and immature neuronal markers in a mouse model of ischemic cerebral stroke
    • Zhang XM, Du F, Yang D, Yu CJ, Huang XN, Liu W, et al. Transplanted bone marrow stem cells relocate to infarct penumbra and co-express endogenous proliferative and immature neuronal markers in a mouse model of ischemic cerebral stroke. BMC Neurosci. 2010;11:138.
    • (2010) BMC Neurosci. , vol.11 , pp. 138
    • Zhang, X.M.1    Du, F.2    Yang, D.3    Yu, C.J.4    Huang, X.N.5    Liu, W.6
  • 71
    • 77954832481 scopus 로고    scopus 로고
    • Bone marrow mononuclear cells promote proliferation of endogenous neural stem cells through vascular niches after cerebral infarction
    • Nakano-Doi A, Nakagomi T, Fujikawa M, Nakagomi N, Kubo S, Lu S, et al. Bone marrow mononuclear cells promote proliferation of endogenous neural stem cells through vascular niches after cerebral infarction. Stem Cells. 2010;28:1292-302.
    • (2010) Stem Cells. , vol.28 , pp. 1292-1302
    • Nakano-Doi, A.1    Nakagomi, T.2    Fujikawa, M.3    Nakagomi, N.4    Kubo, S.5    Lu, S.6
  • 72
    • 51949107296 scopus 로고    scopus 로고
    • Mesenchymal stem cells promote proliferation of endogenous neural stem cells and survival of newborn cells in a rat stroke model
    • Yoo SW, Kim SS, Lee SY, Lee HS, Kim HS, Lee YD, et al. Mesenchymal stem cells promote proliferation of endogenous neural stem cells and survival of newborn cells in a rat stroke model. Exp Mol Med. 2008;40:387-97.
    • (2008) Exp Mol Med. , vol.40 , pp. 387-397
    • Yoo, S.W.1    Kim, S.S.2    Lee, S.Y.3    Lee, H.S.4    Kim, H.S.5    Lee, Y.D.6
  • 73
    • 50849090271 scopus 로고    scopus 로고
    • Transplanted bone marrow stromal cells migrate, differentiate and improve motor function in rats with experimentally induced cerebral stroke
    • Chen JR, Cheng GY, Sheu CC, Tseng GF, Wang TJ, Huang YS. Transplanted bone marrow stromal cells migrate, differentiate and improve motor function in rats with experimentally induced cerebral stroke. J Anat. 2008;213:249-58.
    • (2008) J Anat. , vol.213 , pp. 249-258
    • Chen, J.R.1    Cheng, G.Y.2    Sheu, C.C.3    Tseng, G.F.4    Wang, T.J.5    Huang, Y.S.6
  • 74
    • 79960003566 scopus 로고    scopus 로고
    • Transplantation of Flk-1z human bone marrow-derived mesenchymal stem cells promotes angiogenesis and neurogenesis after cerebral ischemia in rats
    • Bao X, Feng M, Wei J, Han Q, Zhao H, Li G, et al. Transplantation of Flk-1z human bone marrow-derived mesenchymal stem cells promotes angiogenesis and neurogenesis after cerebral ischemia in rats. Eur J Neurosci. 2011;34:87-98.
    • (2011) Eur J Neurosci. , vol.34 , pp. 87-98
    • Bao, X.1    Feng, M.2    Wei, J.3    Han, Q.4    Zhao, H.5    Li, G.6
  • 75
    • 78650517407 scopus 로고    scopus 로고
    • Transplantation of human bone marrow-derived mesenchymal stem cells promotes behavioral recovery and endogenous neurogenesis after cerebral ischemia in rats
    • Bao X, Wei J, Feng M, Lu S, Li G, Dou W, et al. Transplantation of human bone marrow-derived mesenchymal stem cells promotes behavioral recovery and endogenous neurogenesis after cerebral ischemia in rats. Brain Res. 2011;1367:103-13.
    • (2011) Brain Res. , vol.1367 , pp. 103-113
    • Bao, X.1    Wei, J.2    Feng, M.3    Lu, S.4    Li, G.5    Dou, W.6
  • 76
    • 0035954362 scopus 로고    scopus 로고
    • Treatment of stroke in rat with intracarotid administration of marrow stromal cells
    • Li Y, Chen J, Wang L, Lu M, Chopp M. Treatment of stroke in rat with intracarotid administration of marrow stromal cells. Neurology. 2001;56:1666-72.
    • (2001) Neurology. , vol.56 , pp. 1666-1672
    • Li, Y.1    Chen, J.2    Wang, L.3    Lu, M.4    Chopp, M.5
  • 77
    • 43449092523 scopus 로고    scopus 로고
    • Human adult bone marrow-derived somatic cell therapy results in functional recovery and axonal plasticity following stroke in the rat
    • Andrews EM, Tsai SY, Johnson SC, Farrer JR, Wagner JP, Kopen GC, et al. Human adult bone marrow-derived somatic cell therapy results in functional recovery and axonal plasticity following stroke in the rat. Exp Neurol. 2008;211:588-92.
    • (2008) Exp Neurol. , vol.211 , pp. 588-592
    • Andrews, E.M.1    Tsai, S.Y.2    Johnson, S.C.3    Farrer, J.R.4    Wagner, J.P.5    Kopen, G.C.6
  • 78
    • 0036118625 scopus 로고    scopus 로고
    • Human bone marrow stem cells exhibit neural phenotypes and ameliorate neurological deficits after grafting into the ischemic brain of rats
    • Zhao LR, Duan WM, Reyes M, Keene CD, Verfaillie CM, Low WC. Human bone marrow stem cells exhibit neural phenotypes and ameliorate neurological deficits after grafting into the ischemic brain of rats. Exp Neurol. 2002;174:11-20.
    • (2002) Exp Neurol. , vol.174 , pp. 11-20
    • Zhao, L.R.1    Duan, W.M.2    Reyes, M.3    Keene, C.D.4    Verfaillie, C.M.5    Low, W.C.6
  • 79
    • 51649129232 scopus 로고    scopus 로고
    • Mesenchymal stem cells transplantation could be beneficial for treatment of experimental ischemic stroke in rats
    • Pavlichenko N, Sokolova I, Vijde S, Shvedova E, Alexandrov G, Krouglyakov P, et al. Mesenchymal stem cells transplantation could be beneficial for treatment of experimental ischemic stroke in rats. Brain Res. 2008;1233:203-13.
    • (2008) Brain Res. , vol.1233 , pp. 203-213
    • Pavlichenko, N.1    Sokolova, I.2    Vijde, S.3    Shvedova, E.4    Alexandrov, G.5    Krouglyakov, P.6
  • 80
    • 79959895117 scopus 로고    scopus 로고
    • Effects of transplantation with bone marrow-derived mesenchymal stem cells modified by Survivin on experimental stroke in rats
    • Liu N, Zhang Y, Fan L, Yuan M, Du H, Cheng R, et al. Effects of transplantation with bone marrow-derived mesenchymal stem cells modified by Survivin on experimental stroke in rats. J Transl Med. 2011;9:105.
    • (2011) J Transl Med. , vol.9 , pp. 105
    • Liu, N.1    Zhang, Y.2    Fan, L.3    Yuan, M.4    Du, H.5    Cheng, R.6
  • 82
    • 78649804099 scopus 로고    scopus 로고
    • Changes in host blood factors and brain glia accompanying the functional recovery after systemic administration of bone marrow stem cells in ischemic stroke rats
    • Yang M, Wei X, Li J, Heine LA, Rosenwasser R, Iacovitti L. Changes in host blood factors and brain glia accompanying the functional recovery after systemic administration of bone marrow stem cells in ischemic stroke rats. Cell Transplant. 2010;19:1073-84.
    • (2010) Cell Transplant. , vol.19 , pp. 1073-1084
    • Yang, M.1    Wei, X.2    Li, J.3    Heine, L.A.4    Rosenwasser, R.5    Iacovitti, L.6
  • 83
    • 0038024241 scopus 로고    scopus 로고
    • Rocks: Multifunctional kinases in cell behaviour
    • Riento K, Ridley AJ. Rocks: multifunctional kinases in cell behaviour. Nat Rev Mol Cell Biol. 2003;4:446-56.
    • (2003) Nat Rev Mol Cell Biol. , vol.4 , pp. 446-456
    • Riento, K.1    Ridley, A.J.2


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