Flotillin-involved uptake of silica nanoparticles and responses of an alveolar-capillary barrier in vitro

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 84, Issue 2, 2013, Pages 275-287

  Kasper, Jennifer ^a   Hermanns, Maria I ^a   Bantz, Christoph ^b   Utech, Stefanie ^b   Koshkina, Olga ^c   Maskos, Michael ^b,c,d   Brochhausen, Christoph ^a   Pohl, Christine ^a   Fuchs, Sabine ^e   Unger, Ronald E ^a   James Kirkpatrick, C ^a  

^a UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^b JOHANNES GUTENBERG UNIVERSITY   (Germany)

^c BAM FEDERAL INSTITUTE FOR MATERIALS RESEARCH AND TESTING   (Germany)

^d INSTITUT FÜR MIKROTECHNIK MAINZ GMBH   (Germany)

^e UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

Author keywords

Alveolar capillary barrier; Endocytosis; Flotillin 1 2 dependent uptake trafficking; NP uptake; NP transport; Silica nanoparticles

Indexed keywords

CLATHRIN; FLOTILLIN 1; FLOTILLIN 2; INTERLEUKIN 8; NANOPARTICLE; SILICON DIOXIDE;

ARTICLE; CAPILLARY; CAVEOLA; CELL FATE; CELL VIABILITY; COCULTURE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; ELECTRIC RESISTANCE; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; IN VITRO STUDY; INFLAMMATION; LUNG ALVEOLUS EPITHELIUM; MICROVASCULAR ENDOTHELIAL CELL; MONOCULTURE; TRANSMISSION ELECTRON MICROSCOPY;

CAPILLARIES; CELL LINE; CELL SURVIVAL; COCULTURE TECHNIQUES; COLORING AGENTS; DRUG DELIVERY SYSTEMS; ELECTRIC IMPEDANCE; ENDOCYTOSIS; ENDOTHELIAL CELLS; HUMANS; INFLAMMATION; LIPID BILAYERS; MEMBRANE PROTEINS; MICROCIRCULATION; NANOMEDICINE; NANOPARTICLES; PULMONARY ALVEOLI; RHODAMINES; SILICON DIOXIDE;

EID: 84878309541     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2012.10.011     Document Type: Article

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