Influence of diabetes mellitus on vertebral fractures in men with acromegaly

Endocrine

Volumn 40, Issue 1, 2011, Pages 102-108

  Mazziotti, Gherardo ^a,b   Gola, Monica ^a   Bianchi, Antonio ^c   Porcelli, Teresa ^a   Giampietro, Antonella ^c   Cimino, Vincenzo ^c   Doga, Mauro ^a   Gazzaruso, Carmine ^d,e   De Marinis, Laura ^c   Giustina, Andrea ^a  

^a UNIVERSITY OF BRESCIA   (Italy)

^b CARLO POMA HOSPITAL   (Italy)

^c CATHOLIC UNIVERSITY   (Italy)

^d Clinical Institute Beato Matteo ICBM   (Italy)

^e IRCCS POLICLINICO SAN DONATO   (Italy)

Author keywords

Acromegaly; Diabetes mellitus; Osteoporosis; Vertebral fractures

Indexed keywords

GROWTH HORMONE; INSULIN; REPAGLINIDE; SOMATOMEDIN C; SOMATOSTATIN DERIVATIVE; SULFONYLUREA;

ACROMEGALY; ADULT; AGED; ARTICLE; BONE DENSITY; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DISEASE ASSOCIATION; DISEASE DURATION; DUAL ENERGY X RAY ABSORPTIOMETRY; GROWTH HORMONE RELEASE; HUMAN; MAJOR CLINICAL STUDY; MALE; MORPHOMETRICS; NEUROSURGERY; NON INSULIN DEPENDENT DIABETES MELLITUS; PREVALENCE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SPINE RADIOGRAPHY; VERTEBRA FRACTURE;

EID: 80755138368     PISSN: 1355008X     EISSN: 15590100     Source Type: Journal    
DOI: 10.1007/s12020-011-9486-x     Document Type: Article

References (41)

1. A. Giustina, G. Mazziotti, E. Canalis, Growth hormone, insulinlike growth factors, and the skeleton. Endocr. Rev. 29, 535-559 (2008)
2. E. Canalis, A. Giustina, J.P. Bilezikian, Mechanisms of anabolic therapies for osteoporosis. N. Engl. J. Med. 35, 7905-7916 (2007)
3. S. Bonadonna, G. Mazziotti, M. Nuzzo, A. Bianchi, A. Fusco, L. De Marinis, A. Giustina, Increased prevalence of radiological spinal deformities in active acromegaly: a cross-sectional study in postmenopausal women. J. Bone Miner. Res. 20, 1837-1844 (2005) (Pubitemid 41361885)
4. G. Mazziotti, A. Bianchi, S. Bonadonna, V. Cimino, I. Patelli, A. Fusco, A. Pontecorvi, L. De Marinis, A. Giustina, Prevalence of vertebral fractures in men with acromegaly. J. Clin. Endocrinol. Metab. 93, 4649-4655 (2008)
5. M.J. Wassenaar, N.R. Biermasz, N.A. Hamdy, M.C. Zillikens, J.B. van Meurs, F. Rivadeneira, A. Hofman, A.G. Uitterlinden, M.P. Stokkel, F. Roelfsema, M. Kloppenburg, H.M. Kroon, J.A. Romijn, A.M. Pereira, High prevalence of vertebral fractures despite normal bone mineral density in patients with long-term controlled acromegaly. Eur. J. Endocrinol. 164, 475-483 (2011)
6. A. Giustina, F.F. Casanueva, F. Cavagnini, P. Chanson, D. Clemmons, L.A. Frohman, R. Gaillard, K. Ho, P. Jaquet, D.L. Kleinberg, S.W. Lamberts, G. Lombardi, M. Sheppard, C.J. Strasburger, M.L. Vance, J.A. Wass, S. Melmed, Pituitary Society and the European Neuroendocrine Association, Diagnosis and treatment of acromegaly complications. J. Endocrinol. Invest. 26, 1242-1247 (2003) (Pubitemid 38324744)
7. G. Mazziotti, S. Bonadonna, M. Doga, I. Patelli, C. Gazzaruso, S.B. Solerte, E. De Menis, A. Giustina, Biochemical evaluation of patients with active acromegaly and type 2 diabetes mellitus: efficacy and safety of the galanin test. Neuroendocrinology 88, 299-304 (2008)
8. G. Mazziotti, I. Floriani, S. Bonadonna, V. Torri, P. Chanson, A. Giustina, Effects of somatostatin analogs on glucose homeostasis: a metaanalysis of acromegaly studies. J. Clin. Endocrinol. Metab. 94, 1500-1508 (2009)
9. A. Colao, D. Ferone, P. Marzullo, G. Lombardi, Systemic complications of acromegaly: epidemiology, pathogenesis and management. Endocr. Rev. 25, 102-152 (2004) (Pubitemid 38269977)
10. M.L. Jaffrain-Rea, C. Moroni, R. Baldelli, C. Battista, P. Maffei, M. Terzolo, M. Correra, M.R. Ghiggi, E. Ferretti, A. Angeli, N. Sicolo, V. Trischitta, A. Liuzzi, R. Cassone, G. Tamburrano, Relationship between blood pressure and glucose tolerance in acromegaly. Clin. Endocrinol. (Oxf.) 54, 189-195 (2001) (Pubitemid 32193520)
11. A. Räkel, O. Sheehy, E. Rahme, J. LeLorier, Osteoporosis among patients with type 1 and type 2 diabetes. Diabetes Metab. 34, 193-205 (2008)
12. P. Vestergaard, Discrepancies in bone mineral density and fracture risk in patients with type 1 and type 2 diabetes-a metaanalysis. Osteoporos. Int. 18, 427-444 (2007) (Pubitemid 46354916)
13. T. Mancini, G. Mazziotti, M. Doga, R. Carpinteri, N. Simetovic, P.P. Vescovi, A. Giustina, Vertebral fractures in males with type 2 diabetes treated with rosiglitazone. Bone 45, 784-788 (2009)
14. A. Giustina, A. Barkan, F.F. Casanueva, F. Cavagnini, L. Frohman, K. Ho, J. Veldhuis, J. Wass, K. Von Werder, S. Melmed, Criteria for cure of acromegaly: a consensus statement. J. Clin. Endocrinol. Metab. 85, 526-529 (2000) (Pubitemid 32273628)
15. A. Giustina, P. Chanson, M.D. Bronstein, A. Klibanski, S. Lamberts, F.F. Casanueva, P. Trainer, E. Ghigo, K. Ho, S. Melmed, Acromegaly Consensus Group, A consensus on criteria for cure of acromegaly. J. Clin. Endocrinol. Metab. 95, 3141-3148 (2010)
16. I. Donangelo, S. Melmed, Treatment of acromegaly: future. Endocrine 28, 123-128 (2005) (Pubitemid 43004810)
17. S. Melmed, A. Colao, A. Barkan, M. Molitch, A.B. Grossman, D. Kleinberg, D. Clemmons, P. Chanson, E. Laws, J. Schlechte, M.L. Vance, K. Ho, A. Giustina, Acromegaly Consensus Group, Guidelines for acromegaly management: an update. J. Clin. Endocrinol. Metab. 94, 1509-1517 (2009)
18. American Diabetes Association, Diagnosis and classification of diabetes mellitus. Diabetes Care 34(Suppl 1), S62-S69 (2011)
19. A. Vermeulen, L. Verdonck, J.M. Kaufman, A critical evaluation of simple methods for the estimation of free testosterone in serum. J. Clin. Endocrinol. Metab. 84, 3666-3672 (1999) (Pubitemid 30645223)
20. G. Mazziotti, E. Canalis, A. Giustina, Drug-induced osteoporosis: mechanisms and clinical implications. Am. J. Med. 123, 877-884 (2010)
21. H.K. Genant, M. Jergas, L. Palermo, M. Nevitt, R.S. Valentin, D. Black, S.R. Cummings, Comparison of semiquantitative visual and quantitative morphometric assessment of prevalent and incident vertebral fractures in osteoporosis The Study of Osteoporotic Fractures Research Group. J. Bone Miner. Res. 11, 984-996 (1996) (Pubitemid 26200050)
22. G. Mazziotti, A. Bianchi, S. Bonadonna, M. Nuzzo, V. Cimino, A. Fusco, L. De Marinis, A. Giustina, Increased prevalence of radiological spinal deformities in adult patients with GH deficiency: influence of GH replacement therapy. J. Bone Miner. Res. 21, 520-528 (2006)
23. S. Ezzat, S. Melmed, D. Endres, D.R. Eyre, F.R. Singer, Biochemical assessment of bone formation and resorption in acromegaly. J. Clin. Endocrinol. Metab. 76, 1452-1457 (1993) (Pubitemid 23164360)
24. T. Ueland, E.N. Ebbesen, J.S. Thomsen, L. Mosekilde, K. Brixen, A. Flyvbjerg, J. Bollerslev, Decreased trabecular bone biomechanical competence, apparent density, IGF-II and IGFBP-5 content in acromegaly. Eur. J. Clin. Invest. 32, 122-128 (2002) (Pubitemid 36232733)
25. C. Battista, I. Chiodini, S. Muscarella, G. Guglielmi, M.L. Mascia, V. Carnevale, A. Scillitani, Spinal volumetric trabecular bone mass in acromegalic patients: a longitudinal study. Clin. Endocrinol. (Oxf.) 70, 378-382 (2009)
26. M.J. Wassenaar, N.R. Biermasz, J. Bijsterbosch, A.M. Pereira, I. Meulenbelt, J.W. Smit, F. Roelfsema, H.M. Kroon, J.A. Romijn, M. Kloppenburg, Arthropathy in long-term cured acromegaly is characterised by osteophytes without joint space narrowing: a comparison with generalised osteoarthritis. Ann. Rheum. Dis. 70, 320-325 (2011)
27. G.P. Lesse, W.D. Fraser, R. Farquharson, L. Hipkin, J.P. Vora, Gonadal status is an important determinant of bone density in acromegaly. Clin. Endocrinol. (Oxf.) 48, 59-65 (1998) (Pubitemid 28122434)
28. A. Scillitani, C. Battista, I. Chiodini, V. Carnevale, S. Fusilli, E. Ciccarelli, M. Terzolo, G. Oppizzi, M. Arosio, M. Gasperi, G. Arnaldi, A. Colao, R. Baldelli, M.R. Ghiggi, D. Gaia, C. Di Somma, V. Trischitta, A. Liuzzi, Bone mineral density in acromegaly: the effect of gender, disease activity and gonadal status. Clin. Endocrinol. (Oxf.) 58, 725-731 (2003) (Pubitemid 36702732)
29. T.L. Clemens, G. Karsenty, The osteoblast: an insulin target cell controlling glucose homeostasis. J. Bone Miner. Res. 26, 677-680 (2011)
30. C.J. Rosen, K.J. Motyl, No bones about it: insulin modulates skeletal remodeling. Cell 142, 98-200 (2010)
31. N.K. Lee, H. Sowa, E. Hinoi, M. Ferron, J.D. Ahn, C. Confavreux, R. Dacquin, P.J. Mee, M.D. McKee, D.Y. Jung, Z. Zhang, J.K. Kim, F. Mauvais-Jarvis, P. Ducy, G. Karsenty, Endocrine regulation of energy metabolism by the skeleton. Cell 130, 456-469 (2007) (Pubitemid 47208519)
32. J.M. Gimble, M.E. Nuttall, Bone and fat: old questions, new insights. Endocrine 23, 183-188 (2004) (Pubitemid 39140232)
33. K. Aǧbaht, A. Gürlek, J. Karakaya, M. Bayraktar, Circulating adiponectin represents a biomarker of the association between adiposity and bone mineral density. Endocrine 35, 371-379 (2009)
34. I. Kanazawa, T. Yamaguchi, M. Yamamoto, M. Yamauchi, S. Yano, T. Sugimoto, Relationships between serum adiponectin levels versus bone mineral density, bone metabolic markers, and vertebral fractures in type 2 diabetes mellitus. Eur. J. Endocrinol. 160, 265-273 (2009)
35. N. Sucunza, M.J. Barahona, E. Resmini, J.M. Fernández-Real, W. Ricart, J. Farrerons, J. Rodríguez Espinosa, A.M. Marin, T. Puig, S.M. Webb, A link between bone mineral density and serum adiponectin and visfatin levels in acromegaly. J. Clin. Endocrinol. Metab. 94, 3889-3896 (2009)
36. M.C. Nevitt, B. Ettinger, D.M. Black, K. Stone, S.A. Jamal, K. Ensrud, M. Segal, H.K. Genant, S.R. Cummings, The association of radiographically detected vertebral fractures with back pain and function: a prospective study. Ann. Intern. Med. 128, 793-800 (1998) (Pubitemid 28267711)
37. T. Jalava, S. Sarna, L. Pylkkänen, B. Mawer, J.A. Kanis, P. Selby, M. Davies, J. Adams, R.M. Francis, J. Robinson, E. McCloskey, Association between vertebral fracture and increased mortality in osteoporotic patients. J. Bone Miner. Res. 18, 1254-1260 (2003) (Pubitemid 37294918)
38. S. Bossoni, G. Mazziotti, C. Gazzaruso, D. Martinelli, S. Orini, S.B. Solerte, G. Romanelli, A. Giustina, Relationship between instrumental activities of daily living and blood glucose control in elderly subjects with type 2 diabetes. Age Ageing 37, 222-225 (2008) (Pubitemid 351445197)
39. M. Sherlock, J. Ayuk, J.W. Tomlinson, A.A. Toogood, A. Aragon- Alonso, M.C. Sheppard, A.S. Bates, P.M. Stewart, Mortality in patients with pituitary disease. Endocr. Rev. 31, 301-342 (2010)
40. G. Mazziotti, A. Bianchi, V. Cimino, S. Bonadonna, P. Martini, A. Fusco, L. De Marinis, A. Giustina, Effect of gonadal status on bone mineral density and radiological spinal deformities in adult patients with growth hormone deficiency. Pituitary 11, 55-61 (2008) (Pubitemid 351168085)
41. G. Mazziotti, T. Porcelli, M. Mormando, E. De Menis, A. Bianchi, C. Mejia, T. Mancini, L. De Marinis, A. Giustina, Vertebral fractures in males with prolactinoma. Endocrine 39, 288-293 (2011)