A novel transcription mechanism activated by ethanol: Induction of Slc7a11 gene expression via inhibition of the DNA-binding activity of transcriptional repressor octamer-binding transcription factor 1 (OCT-1)

Journal of Biological Chemistry

Volumn 288, Issue 21, 2013, Pages 14815-14823

  Lin, Xinghua ^a   Yang, Hong ^a   Zhang, Hongfeng ^a   Zhou, LiChun ^a   Guo, ZhongMao ^a  

^a MEHARRY MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA SEQUENCE ANALYSIS; ENDOPLASMIC RETICULUM STRESS; HEPATIC STELLATE CELLS; NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR 2; PROMOTER ACTIVITIES; TRANSCRIPTION MECHANISM; TRANSCRIPTION START SITE; TRANSCRIPTIONAL REPRESSORS;

CELL MEMBRANES; DNA SEQUENCES; ENZYME ACTIVITY; NUCLEIC ACIDS; TRANSCRIPTION; TRANSCRIPTION FACTORS;

ETHANOL;

ACTIVATING TRANSCRIPTION FACTOR 4; ADENOSINE TRIPHOSPHATE; ALCOHOL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MEMBRANE PROTEIN; MESSENGER RNA; OCTAMER TRANSCRIPTION FACTOR 1; SOLUTE CARRIER FAMILY 7 MEMBER 11; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA BINDING MOTIF; DNA SEQUENCE; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION; GENE REPRESSION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; STELLATE CELL; UPREGULATION;

ALCOHOL; HEPATIC STELLATE CELLS; MOUSE; OCTAMER-BINDING TRANSCRIPTION FACTOR 1; SOLUTE CARRIER FAMILY 7, MEMBER 11; TRANSCRIPTION FACTORS; TRANSPORTERS;

AMINO ACID MOTIFS; AMINO ACID TRANSPORT SYSTEM Y+; ANIMALS; CENTRAL NERVOUS SYSTEM DEPRESSANTS; ENDOPLASMIC RETICULUM STRESS; ETHANOL; HEPATIC STELLATE CELLS; MICE; MICE, TRANSGENIC; OCTAMER TRANSCRIPTION FACTOR-1; OXIDATIVE STRESS; REPRESSOR PROTEINS; RESPONSE ELEMENTS; RNA, MESSENGER; SEQUENCE DELETION; UP-REGULATION;

EID: 84878255480     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.466565     Document Type: Article

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