-
1
-
-
0036125511
-
Interdependent nuclear accumulation of budding yeast Cdt1 and Mcm2-7 during G1 phase
-
DOI 10.1038/ncb757
-
Tanaka, S., and Diffley, J. F. (2002) Interdependent nuclear accumulation of budding yeast Cdt1 and Mcm2-7 during G1 phase. Nat. Cell Biol. 4, 198-207 (Pubitemid 34218193)
-
(2002)
Nature Cell Biology
, vol.4
, Issue.3
, pp. 198-207
-
-
Tanaka, S.1
Diffley, J.F.X.2
-
2
-
-
33750457317
-
An essential role for Orc6 in DNA replication through maintenance of pre-replicative complexes
-
DOI 10.1038/sj.emboj.7601391, PII 7601391
-
Semple, J. W., Da-Silva, L. F., Jervis, E. J., Ah-Kee, J., Al-Attar, H., Kummer, L., Heikkila, J. J., Pasero, P., and Duncker, B. P. (2006) An essential role for Orc6 in DNA replication through maintenance of pre-replicative complexes. EMBO J. 25, 5150-5158 (Pubitemid 44658532)
-
(2006)
EMBO Journal
, vol.25
, Issue.21
, pp. 5150-5158
-
-
Semple, J.W.1
Da-Silva, L.F.2
Jervis, E.J.3
Ah-Kee, J.4
Al-Attar, H.5
Kummer, L.6
Heikkila, J.J.7
Pasero, P.8
Duncker, B.P.9
-
3
-
-
36249005517
-
Orc6 is required for dynamic recruitment of Cdt1 during repeated Mcm2-7 loading
-
DOI 10.1101/gad.1596807
-
Chen, S., de Vries, M. A., and Bell, S. P. (2007) Orc6 is required for dynamic recruitment of Cdt1 during repeated Mcm2-7 loading. Genes Dev. 21, 2897-2907 (Pubitemid 350133438)
-
(2007)
Genes and Development
, vol.21
, Issue.22
, pp. 2897-2907
-
-
Chen, S.1
De Vries, M.A.2
Bell, S.P.3
-
4
-
-
29544435484
-
Sequential ATP hydrolysis by Cdc6 and ORC directs loading of the Mcm2-7 helicase
-
DOI 10.1016/j.molcel.2005.11.023, PII S1097276505018113
-
Randell, J. C., Bowers, J. L., Rodríguez, H. K., and Bell, S. P. (2006) Sequential ATP hydrolysis by Cdc6 and ORC directs loading of the Mcm2-7 helicase. Mol. Cell 21, 29-39 (Pubitemid 43017846)
-
(2006)
Molecular Cell
, vol.21
, Issue.1
, pp. 29-39
-
-
Randell, J.C.W.1
Bowers, J.L.2
Rodriguez, H.K.3
Bell, S.P.4
-
5
-
-
73949091058
-
A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication
-
Evrin, C., Clarke, P., Zech, J., Lurz, R., Sun, J., Uhle, S., Li, H., Stillman, B., and Speck, C. (2009) A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication. Proc. Natl. Acad. Sci. U.S.A. 106, 20240-20245
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 20240-20245
-
-
Evrin, C.1
Clarke, P.2
Zech, J.3
Lurz, R.4
Sun, J.5
Uhle, S.6
Li, H.7
Stillman, B.8
Speck, C.9
-
6
-
-
70350751416
-
Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing
-
Remus, D., Beuron, F., Tolun, G., Griffith, J. D., Morris, E. P., and Diffley, J. F. (2009) Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing. Cell 139, 719-730
-
(2009)
Cell
, vol.139
, pp. 719-730
-
-
Remus, D.1
Beuron, F.2
Tolun, G.3
Griffith, J.D.4
Morris, E.P.5
Diffley, J.F.6
-
7
-
-
78149462002
-
Mec1 is one of multiple kinases that prime the Mcm2-7 helicase for phosphorylation by Cdc7
-
Randell, J. C., Fan, A., Chan, C., Francis, L. I., Heller, R. C., Galani, K., and Bell, S. P. (2010) Mec1 is one of multiple kinases that prime the Mcm2-7 helicase for phosphorylation by Cdc7. Mol. Cell 40, 353-363
-
(2010)
Mol. Cell
, vol.40
, pp. 353-363
-
-
Randell, J.C.1
Fan, A.2
Chan, C.3
Francis, L.I.4
Heller, R.C.5
Galani, K.6
Bell, S.P.7
-
8
-
-
40549108563
-
Cell cycle regulation of DNA replication
-
Sclafani, R. A., and Holzen, T. M. (2007) Cell cycle regulation of DNA replication. Annu. Rev. Genet. 41, 237-280
-
(2007)
Annu. Rev. Genet.
, vol.41
, pp. 237-280
-
-
Sclafani, R.A.1
Holzen, T.M.2
-
9
-
-
0033215306
-
Cdc7p-Dbf4p kinase binds to chromatin during S phase and is regulated by both the APC and the RAD53 checkpoint pathway
-
DOI 10.1093/emboj/18.19.5334
-
Weinreich, M., and Stillman, B. (1999) Cdc7p-Dbf4p kinase binds to chromatin during S phase and is regulated by both the APC and the RAD53 checkpoint pathway. EMBO J. 18, 5334-5346 (Pubitemid 29465583)
-
(1999)
EMBO Journal
, vol.18
, Issue.19
, pp. 5334-5346
-
-
Weinreich, M.1
Stillman, B.2
-
10
-
-
0031006539
-
mcm5/cdc46-bob1 bypasses the requirement for the S phase activator Cdc7p
-
DOI 10.1073/pnas.94.7.3151
-
Hardy, C. F., Dryga, O., Seematter, S., Pahl, P. M., and Sclafani, R. A. (1997) Mcm5/Cdc46-Bob1 bypasses the requirement for the S phase activator Cdc7p. Proc. Natl. Acad. Sci. U.S.A. 94, 3151-3155 (Pubitemid 27157279)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.7
, pp. 3151-3155
-
-
Hardy, C.F.S.1
Dryga, O.2
Seematter, S.3
Pahl, P.M.B.4
Sclafani, R.A.5
-
11
-
-
35648944221
-
Structural changes in Mcm5 protein bypass Cdc7-Dbf4 function and reduce replication origin efficiency in Saccharomyces cerevisiae
-
DOI 10.1128/MCB.00997-07
-
Hoang, M. L., Leon, R. P., Pessoa-Brandao, L., Hunt, S., Raghuraman, M. K., Fangman, W. L., Brewer, B. J., and Sclafani, R. A. (2007) Structural changes in Mcm5 protein bypass Cdc7-Dbf4 function and reduce replication origin efficiency in Saccharomyces cerevisiae. Mol. Cell. Biol. 27, 7594-7602 (Pubitemid 350033664)
-
(2007)
Molecular and Cellular Biology
, vol.27
, Issue.21
, pp. 7594-7602
-
-
Hoang, M.L.1
Leon, R.P.2
Pessoa-Brandao, L.3
Hunt, S.4
Raghuraman, M.K.5
Fangman, W.L.6
Brewer, B.J.7
Sclafani, R.A.8
-
12
-
-
73849129578
-
The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4
-
Sheu, Y. J., and Stillman, B. (2010) The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4. Nature 463, 113-117
-
(2010)
Nature
, vol.463
, pp. 113-117
-
-
Sheu, Y.J.1
Stillman, B.2
-
13
-
-
33749075373
-
Cdc7-Dbf4 phosphorylates MCM proteins via a docking site-mediated mechanism to promote S phase progression
-
Sheu, Y. J., and Stillman, B. (2006) Cdc7-Dbf4 phosphorylates MCM proteins via a docking site-mediated mechanism to promote S phase progression. Mol. Cell 24, 101-113
-
(2006)
Mol. Cell
, vol.24
, pp. 101-113
-
-
Sheu, Y.J.1
Stillman, B.2
-
14
-
-
79959957543
-
Eukaryotic origin-dependent DNA replication in vitro reveals sequential action of DDK and S-CDK kinases
-
Heller, R. C., Kang, S., Lam, W. M., Chen, S., Chan, C. S., and Bell, S. P. (2011) Eukaryotic origin-dependent DNA replication in vitro reveals sequential action of DDK and S-CDK kinases. Cell 146, 80-91
-
(2011)
Cell
, vol.146
, pp. 80-91
-
-
Heller, R.C.1
Kang, S.2
Lam, W.M.3
Chen, S.4
Chan, C.S.5
Bell, S.P.6
-
15
-
-
4444276755
-
ORC-associated replication factors as biomarkers for cancer
-
DOI 10.1016/j.biotechadv.2004.06.001, PII S0734975004000503
-
Semple, J. W., and Duncker, B. P. (2004) ORC-associated replication factors as biomarkers for cancer. Biotechnol. Adv. 22, 621-631 (Pubitemid 39204623)
-
(2004)
Biotechnology Advances
, vol.22
, Issue.8
, pp. 621-631
-
-
Semple, J.W.1
Duncker, B.P.2
-
16
-
-
13444270648
-
Control of DNA replication and its potential clinical exploitation
-
DOI 10.1038/nrc1548
-
Gonzalez, M. A., Tachibana, K. E., Laskey, R. A., and Coleman, N. (2005) Control of DNA replication and its potential clinical exploitation. Nat. Rev. Cancer 5, 135-141 (Pubitemid 40215861)
-
(2005)
Nature Reviews Cancer
, vol.5
, Issue.2
, pp. 135-141
-
-
Gonzalez, M.A.1
Tachibana, K.-E.K.2
Laskey, R.A.3
Coleman, N.4
-
17
-
-
33845877445
-
A viable allele of Mcm4 causes chromosome instability and mammary adenocarcinomas in mice
-
DOI 10.1038/ng1936, PII NG1936
-
Shima, N., Alcaraz, A., Liachko, I., Buske, T. R., Andrews, C. A., Munroe, R. J., Hartford, S. A., Tye, B. K., and Schimenti, J. C. (2007) A viable allele of Mcm4 causes chromosome instability and mammary adenocarcinomas in mice. Nat. Genet. 39, 93-98 (Pubitemid 46026507)
-
(2007)
Nature Genetics
, vol.39
, Issue.1
, pp. 93-98
-
-
Shima, N.1
Alcaraz, A.2
Liachko, I.3
Buske, T.R.4
Andrews, C.A.5
Munroe, R.J.6
Hartford, S.A.7
Tye, B.K.8
Schimenti, J.C.9
-
18
-
-
78049417542
-
Incremental genetic perturbations to MCM2-7 expression and subcellular distribution reveal exquisite sensitivity of mice to DNA replication stress
-
Chuang, C. H., Wallace, M. D., Abratte, C., Southard, T., and Schimenti, J. C. (2010) Incremental genetic perturbations to MCM2-7 expression and subcellular distribution reveal exquisite sensitivity of mice to DNA replication stress. PLoS Genet. 6, e1001110
-
(2010)
PLoS Genet.
, vol.6
-
-
Chuang, C.H.1
Wallace, M.D.2
Abratte, C.3
Southard, T.4
Schimenti, J.C.5
-
19
-
-
80052498192
-
Phosphorylation of Mcm2 modulates Mcm2-7 activity and affects the cell's response to DNA damage
-
Stead, B. E., Brandl, C. J., and Davey, M. J. (2011) Phosphorylation of Mcm2 modulates Mcm2-7 activity and affects the cell's response to DNA damage. Nucleic Acids Res. 39, 6998-7008
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 6998-7008
-
-
Stead, B.E.1
Brandl, C.J.2
Davey, M.J.3
-
20
-
-
84860574017
-
Mcm2 phosphorylation and the response to replicative stress
-
Stead, B. E., Brandl, C. J., Sandre, M. K., and Davey, M. J. (2012) Mcm2 phosphorylation and the response to replicative stress. BMC Genet. 13, 36
-
(2012)
BMC Genet.
, vol.13
, pp. 36
-
-
Stead, B.E.1
Brandl, C.J.2
Sandre, M.K.3
Davey, M.J.4
-
21
-
-
70350371630
-
Dbf4-Cdc7 phosphorylation of Mcm2 is required for cell growth
-
Bruck, I., and Kaplan, D. (2009) Dbf4-Cdc7 phosphorylation of Mcm2 is required for cell growth. J. Biol. Chem. 284, 28823-28831
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 28823-28831
-
-
Bruck, I.1
Kaplan, D.2
-
22
-
-
23844512811
-
A mutation in Dbf4 motif M impairs interactions with DNA replication factors and confers increased resistance to genotoxic agents
-
DOI 10.1128/MCB.25.17.7494-7504.2005
-
Varrin, A. E., Prasad, A. A., Scholz, R. P., Ramer, M. D., and Duncker, B. P. (2005) A mutation in Dbf4 motif M impairs interactions with DNA replication factors and confers increased resistance to genotoxic agents. Mol. Cell. Biol. 25, 7494-7504 (Pubitemid 41170113)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.17
, pp. 7494-7504
-
-
Varrin, A.E.1
Prasad, A.A.2
Scholz, R.-P.3
Ramer, M.D.4
Duncker, B.P.5
-
23
-
-
77953640799
-
The Dbf4 motif C zinc finger promotes DNA replication and mediates resistance to genotoxic stress
-
Jones, D. R., Prasad, A. A., Chan, P. K., and Duncker, B. P. (2010) The Dbf4 motif C zinc finger promotes DNA replication and mediates resistance to genotoxic stress. Cell Cycle 9, 2018-2026
-
(2010)
Cell Cycle
, vol.9
, pp. 2018-2026
-
-
Jones, D.R.1
Prasad, A.A.2
Chan, P.K.3
Duncker, B.P.4
-
24
-
-
61849173573
-
Incorporation into the prereplicative complex activates the Mcm2-7 helicase for Cdc7-Dbf4 phosphorylation
-
Francis, L. I., Randell, J. C., Takara, T. J., Uchima, L., and Bell, S. P. (2009) Incorporation into the prereplicative complex activates the Mcm2-7 helicase for Cdc7-Dbf4 phosphorylation. Genes Dev. 23, 643-654
-
(2009)
Genes Dev.
, vol.23
, pp. 643-654
-
-
Francis, L.I.1
Randell, J.C.2
Takara, T.J.3
Uchima, L.4
Bell, S.P.5
-
25
-
-
71549165134
-
Budding yeast Dbf4 sequences required for Cdc7 kinase activation and identification of a functional relationship between the Dbf4 and Rev1 BRCT domains
-
Harkins, V., Gabrielse, C., Haste, L., and Weinreich, M. (2009) Budding yeast Dbf4 sequences required for Cdc7 kinase activation and identification of a functional relationship between the Dbf4 and Rev1 BRCT domains. Genetics 183, 1269-1282
-
(2009)
Genetics
, vol.183
, pp. 1269-1282
-
-
Harkins, V.1
Gabrielse, C.2
Haste, L.3
Weinreich, M.4
-
26
-
-
67650683478
-
ATP binding and hydrolysis by Mcm2 regulate DNA binding by Mcm complexes
-
Stead, B. E., Sorbara, C. D., Brandl, C. J., and Davey, M. J. (2009) ATP binding and hydrolysis by Mcm2 regulate DNA binding by Mcm complexes. J. Mol. Biol. 391, 301-313
-
(2009)
J. Mol. Biol.
, vol.391
, pp. 301-313
-
-
Stead, B.E.1
Sorbara, C.D.2
Brandl, C.J.3
Davey, M.J.4
-
27
-
-
0004265596
-
-
3rd Ed., John Wiley & Sons, New York
-
Ausubel, F., Brent, R., Kingston, R. E., Moore, D. D., Seidman, J. G., Smith, J. A., and Struhl, K. (1995) Short Protocols in Molecular Biology, 3rd Ed., John Wiley & Sons, New York
-
(1995)
Short Protocols in Molecular Biology
-
-
Ausubel, F.1
Brent, R.2
Kingston, R.E.3
Moore, D.D.4
Seidman, J.G.5
Smith, J.A.6
Struhl, K.7
-
28
-
-
26244435980
-
CDK phosphorylation of a novel NLS-NES module distributed between two subunits of the Mcm2-7 complex prevents chromosomal rereplication
-
DOI 10.1091/mbc.E05-05-0412
-
Liku, M. E., Nguyen, V. Q., Rosales, A. W., Irie, K., and Li, J. J. (2005) CDK phosphorylation of a novel NLS-NES module distributed between two subunits of the Mcm2-7 complex prevents chromosomal rereplication. Mol. Biol. Cell 16, 5026-5039 (Pubitemid 41416479)
-
(2005)
Molecular Biology of the Cell
, vol.16
, Issue.10
, pp. 5026-5039
-
-
Liku, M.E.1
Nguyen, V.Q.2
Rosales, A.W.3
Irie, K.4
Li, J.J.5
-
29
-
-
0034069075
-
Think global, act local - How to regulate S phase from individual replication origins
-
DOI 10.1016/S0959-437X(00)00067-8
-
Pasero, P., and Schwob, E. (2000) Think global, act local: how to regulate S phase from individual replication origins. Curr. Opin. Genet. Dev. 10, 178-186 (Pubitemid 30182251)
-
(2000)
Current Opinion in Genetics and Development
, vol.10
, Issue.2
, pp. 178-186
-
-
Pasero, P.1
Schwob, E.2
-
30
-
-
0038475879
-
Reconstitution of the Mcm2-7p heterohexamer, subunit arrangement, and ATP site architecture
-
DOI 10.1074/jbc.M210511200
-
Davey, M. J., Indiani, C., and O'Donnell, M. (2003) Reconstitution of the Mcm2-7p heterohexamer, subunit arrangement, and ATP site architecture. J. Biol. Chem. 278, 4491-4499 (Pubitemid 36800944)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.7
, pp. 4491-4499
-
-
Davey, M.J.1
Indiani, C.2
O'Donnell, M.3
-
31
-
-
1542405310
-
Eukaryotic MCM proteins: Beyond replication initiation
-
Forsburg, S. L. (2004) Eukaryotic MCM proteins: beyond replication initiation. Microbiol. Mol. Biol. Rev. 68, 109-131
-
(2004)
Microbiol. Mol. Biol. Rev.
, vol.68
, pp. 109-131
-
-
Forsburg, S.L.1
-
32
-
-
84863419746
-
Saccharomyces cerevisiae Dbf4 has unique fold necessary for interaction with Rad53 kinase
-
Matthews, L. A., Jones, D. R., Prasad, A. A., Duncker, B. P., and Guarné, A. (2012) Saccharomyces cerevisiae Dbf4 has unique fold necessary for interaction with Rad53 kinase. J. Biol. Chem. 287, 2378-2387
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 2378-2387
-
-
Matthews, L.A.1
Jones, D.R.2
Prasad, A.A.3
Duncker, B.P.4
Guarné, A.5
-
33
-
-
0342368778
-
Hierarchy of S-phase-promoting factors: Yeast Dbf4-Cdc7 kinase requires prior S-phase cyclin-dependent kinase activation
-
DOI 10.1128/MCB.20.11.3795-3806.2000
-
Nougarède, R., Della Seta, F., Zarzov, P., and Schwob, E. (2000) Hierarchy of S-phase-promoting factors: yeast Dbf4-Cdc7 kinase requires prior S phase cyclin-dependent kinase activation. Mol. Cell. Biol. 20, 3795-3806 (Pubitemid 30314479)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.11
, pp. 3795-3806
-
-
Nougarede, R.1
Della, S.F.2
Zarzov, P.3
Schwob, E.4
-
34
-
-
77649276054
-
Histone H3 Thr-45 phosphorylation is a replication-associated post-translational modification in S. cerevisiae
-
Baker, S. P., Phillips, J., Anderson, S., Qiu, Q., Shabanowitz, J., Smith, M. M., Yates, J. R., 3rd, Hunt, D. F., and Grant, P. A. (2010) Histone H3 Thr-45 phosphorylation is a replication-associated post-translational modification in S. cerevisiae. Nat. Cell Biol. 12, 294-298
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 294-298
-
-
Baker, S.P.1
Phillips, J.2
Anderson, S.3
Qiu, Q.4
Shabanowitz, J.5
Smith, M.M.6
Yates III, J.R.7
Hunt, D.F.8
Grant, P.A.9
-
35
-
-
33747432986
-
Excess Mcm2-7 license dormant origins of replication that can be used under conditions of replicative stress
-
DOI 10.1083/jcb.200602108
-
Woodward, A. M., Göhler, T., Luciani, M. G., Oehlmann, M., Ge, X., Gartner, A., Jackson, D. A., and Blow, J. J. (2006) Excess Mcm2-7 license dormant origins of replication that can be used under conditions of replicative stress. J. Cell Biol. 173, 673-683 (Pubitemid 46165576)
-
(2006)
Journal of Cell Biology
, vol.173
, Issue.5
, pp. 673-683
-
-
Woodward, A.M.1
Gohler, T.2
Luciani, M.G.3
Oehlmann, M.4
Ge, X.5
Gartner, A.6
Jackson, D.A.7
Blow, J.J.8
-
36
-
-
57749116059
-
The role of Dbf4/Drf1-dependent kinase Cdc7 in DNA-damage checkpoint control
-
Tsuji, T., Lau, E., Chiang, G. G., and Jiang, W. (2008) The role of Dbf4/Drf1-dependent kinase Cdc7 in DNA-damage checkpoint control. Mol. Cell 32, 862-869
-
(2008)
Mol. Cell
, vol.32
, pp. 862-869
-
-
Tsuji, T.1
Lau, E.2
Chiang, G.G.3
Jiang, W.4
-
37
-
-
50949102890
-
Cdc7-Dbf4 kinase overexpression in multiple cancers and tumor cell lines is correlated with p53 inactivation
-
Bonte, D., Lindvall, C., Liu, H., Dykema, K., Furge, K., and Weinreich, M. (2008) Cdc7-Dbf4 kinase overexpression in multiple cancers and tumor cell lines is correlated with p53 inactivation. Neoplasia 10, 920-931
-
(2008)
Neoplasia
, vol.10
, pp. 920-931
-
-
Bonte, D.1
Lindvall, C.2
Liu, H.3
Dykema, K.4
Furge, K.5
Weinreich, M.6
-
38
-
-
77957796717
-
Minichromosome maintenance proteins 2, 3, and 7 in medulloblastoma: Overexpression and involvement in regulation of cell migration and invasion
-
Lau, K. M., Chan, Q. K., Pang, J. C., Li, K. K., Yeung, W. W., Chung, N. Y., Lui, P. C., Tam, Y. S., Li, H. M., Zhou, L., Wang, Y., Mao, Y., and Ng, H. K. (2010) Minichromosome maintenance proteins 2, 3, and 7 in medulloblastoma: overexpression and involvement in regulation of cell migration and invasion. Oncogene 29, 5475-5489
-
(2010)
Oncogene
, vol.29
, pp. 5475-5489
-
-
Lau, K.M.1
Chan, Q.K.2
Pang, J.C.3
Li, K.K.4
Yeung, W.W.5
Chung, N.Y.6
Lui, P.C.7
Tam, Y.S.8
Li, H.M.9
Zhou, L.10
Wang, Y.11
Mao, Y.12
Ng, H.K.13
|