PGC-1α transcriptional response and mitochondrial adaptation to acute exercise is maintained in skeletal muscle of sedentary elderly males

Biogerontology

Volumn 13, Issue 6, 2012, Pages 621-631

  Cobley, J N ^a   Bartlett, J D ^a   Kayani, A ^b   Murray, S W ^c   Louhelainen, J ^a   Donovan, T ^d   Waldron, S ^e   Gregson, W ^a   Burniston, J G ^a   Morton, J P ^a   Close, G L ^a  

^a LIVERPOOL JOHN MOORES UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

^c LIVERPOOL HEART AND CHEST HOSPITAL   (United Kingdom)

^d GLYNDWR UNIVERSITY   (United Kingdom)

^e STEPPING HILL HOSPITAL   (United Kingdom)

Author keywords

Ageing; COXIV; Exercise; Mitochondrial biogenesis; mtDNA; p38MAPK; Training

Indexed keywords

MITOCHONDRIAL DNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; CYTOCHROME C OXIDASE; HEAT SHOCK PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PPARGC1A PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

ADULT; AGING; ARTICLE; BIOGENESIS; CELL FUNCTION; CONTROLLED STUDY; ENDURANCE TRAINING; HUMAN; HUMAN TISSUE; MALE; MITOCHONDRION; MUSCLE BIOPSY; NORMAL HUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SEDENTARY LIFESTYLE; SKELETAL MUSCLE; VASTUS LATERALIS MUSCLE; AGE; AGED; BIOPSY; EXERCISE; EXERCISE TEST; FITNESS; METABOLISM; METHODOLOGY; MIDDLE AGED; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; QUADRICEPS FEMORIS MUSCLE; SIGNAL TRANSDUCTION;

ADULT; AGE FACTORS; AGED; BIOPSY; DNA, MITOCHONDRIAL; ELECTRON TRANSPORT COMPLEX IV; EXERCISE TEST; HEAT-SHOCK PROTEINS; HUMANS; MALE; MIDDLE AGED; MITOCHONDRIA; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PHYSICAL EXERTION; PHYSICAL FITNESS; QUADRICEPS MUSCLE; SEDENTARY LIFESTYLE; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 84878243375     PISSN: 13895729     EISSN: 15736768     Source Type: Journal    
DOI: 10.1007/s10522-012-9408-1     Document Type: Article

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