Determinants and prognostic significance of an intra-dialysis rise of cardiac troponin i measured by sensitive assay in hemodialysis patients

Clinical Research in Cardiology

Volumn 102, Issue 6, 2013, Pages 439-445

  Assa, Solmaz ^a   Gansevoort, Ron T ^a   Westerhuis, Ralf ^a   Kobold, Anneke C Muller ^a   Voors, Adriaan A ^a   De Jong, Paul E ^a   Bakker, Stephan J L ^a   Franssen, Casper F M ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Cardiac troponin I; Cardiovascular; Hemodialysis; Outcome; Sensitive assay

Indexed keywords

TROPONIN I;

ADULT; AGE; AGED; ARTICLE; CARDIOVASCULAR DISEASE; CHRONIC PATIENT; DIURESIS; FEMALE; FOLLOW UP; GENDER; HEMODIALYSIS; HEMODIALYSIS PATIENT; HUMAN; MAJOR CLINICAL STUDY; MALE; MORTALITY; OUTCOME ASSESSMENT; PROGNOSIS; PROSPECTIVE STUDY;

ADULT; AGED; AGED, 80 AND OVER; CARDIOVASCULAR DISEASES; FEMALE; FOLLOW-UP STUDIES; HUMANS; INCIDENCE; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; REGRESSION ANALYSIS; RENAL DIALYSIS; SENSITIVITY AND SPECIFICITY; TIME FACTORS; TROPONIN I; YOUNG ADULT;

EID: 84878230204     PISSN: 18610684     EISSN: 18610692     Source Type: Journal    
DOI: 10.1007/s00392-013-0551-8     Document Type: Article

References (28)

1. Troyanov S, Ly QH, Schampaert E, Ammann H, Lalumiere G, Madore F, Querin S (2005) Diagnostic specificity and prognostic value of cardiac troponins in asymptomatic chronic haemodialysis patients: a three year prospective study. Heart 91:1227-1228
2. Wang AY, Lai KN (2008) Use of cardiac biomarkers in end-stage renal disease. J Am Soc Nephrol 19:1643-1652
3. Wayand D, Baum H, Schatzle G, Scharf J, Neumeier D (2000) Cardiac troponin T and I in end-stage renal failure. Clin Chem 46:1345-1350
4. Apple FS, Murakami MM, Pearce LA, Herzog CA (2002) Predictive value of cardiac troponin I and T for subsequent death in end-stage renal disease. Circulation 106:2941-2945
5. Khan NA, Hemmelgarn BR, Tonelli M, Thompson CR, Levin A (2005) Prognostic value of troponin T and I among asymptomatic patients with end-stage renal disease: a meta-analysis. Circulation 112:3088-3096
6. Gaiki MR, Devita MV, Michelis MF, Panagopoulos G, Rosenstock JL (2012) Troponin I as a prognostic marker of cardiac events in asymptomatic hemodialysis patients using a sensitive troponin I assay. Int Urol Nephrol 44(6):1841-1845
7. Dasselaar JJ, Slart RH, Knip M, Pruim J, Tio RA, McIntyre CW, de Jong PE, Franssen CF (2009) Haemodialysis is associated with a pronounced fall in myocardial perfusion. Nephrol Dial Transplant 24:604-610
8. McIntyre CW, Burton JO, Selby NM, Leccisotti L, Korsheed S, Baker CS, Camici PG (2008) Hemodialysis-induced cardiac dysfunction is associated with an acute reduction in global and segmental myocardial blood flow. Clin J Am Soc Nephrol 3:19-26
9. Tun A, Khan IA, Win MT, Hussain A, Hla TA, Wattanasuwan N, Vasavada BC, Sacchi TJ (1998) Specificity of cardiac troponin I and creatine kinase-MB isoenzyme in asymptomatic long-term hemodialysis patients and effect of hemodialysis on these cardiac markers. Cardiology 90:280-285
10. Farkouh ME, Robbins MJ, Zafar MU, Shimbo D, Davidson KW, Puttappa R, Winston J, Halperin JL, Epstein EM, Patel M, Talor Z, Chesebro JH (2003) Association between troponin I levels and mortality in stable hemodialysis patients. Am J Med 114:224-226
11. Deleaval P, Descombes E, Magnin JL, Martin PY, Fellay G (2006) Differences in cardiac troponin I and T levels measured in asymptomatic hemodialysis patients with last generation immunoassays. Nephrol Ther 2:75-81
12. Lippi G, Tessitore N, Montagnana M, Salvagno GL, Lupo A, Guidi GC (2008) Influence of sampling time and ultrafiltration coefficient of the dialysis membrane on cardiac troponin I and T. Arch Pathol Lab Med 132:72-76
13. Reichlin T, Hochholzer W, Bassetti S, Steuer S, Stelzig C, Hartwiger S, Biedert S, Schaub N, Buerge C, Potocki M, Noveanu M, Breidthardt T, Twerenbold R, Winkler K, Bingisser R, Mueller C (2009) Early diagnosis of myocardial infarction with sensitive cardiac troponin assays. N Engl J Med 361:858-867
14. Reiter M, Twerenbold R, Reichlin T, Benz B, Haaf P, Meissner J, Hochholzer W, Stelzig C, Freese M, Heinisch C, Balmelli C, Drexler B, Freidank H, Winkler K, Campodarve I, Gea J, Mueller C (2012) Early diagnosis of acute myocardial infarction in patients with pre-existing coronary artery disease using more sensitive cardiac troponin assays. Eur Heart J 33(8):988-997
15. Konno T, Shimizu M, Ino H, Fujino N, Hayashi K, Uchiyama K, Kaneda T, Inoue M, Fujita T, Masuta E, Funada A, Mabuchi H (2005) Differences in diagnostic value of four electrocardiographic voltage criteria for hypertrophic cardiomyopathy in a genotyped population. Am J Cardiol 96:1308-1312
16. Iliou MC, Fumeron C, Benoit MO, Tuppin P, Courvoisier CL, Calonge VM, Moatti N, Buisson C, Jacquot C, Chronic Haemodialysis and New Cardiac Markers Evaluation (CHANCE) Study (2001) Factors associated with increased serum levels of cardiac troponins T and I in chronic haemodialysis patients: chronic haemodialysis and new cardiac markers evaluation (CHANCE) study. Nephrol Dial Transplant 16:1452-1458
17. Conway B, McLaughlin M, Sharpe P, Harty J (2005) Use of cardiac troponin T in diagnosis and prognosis of cardiac events in patients on chronic haemodialysis. Nephrol Dial Transplant 20:2759-2764
18. Metra M, Bettari L, Pagani F, Lazzarini V, Lombardi C, Carubelli V, Bonetti G, Bugatti S, Parrinello G, Caimi L, Felker GM, Dei Cas L (2012) Troponin T levels in patients with acute heart failure: clinical and prognostic significance of their detection and release during hospitalisation. Clin Res Cardiol 101:663-672
19. Mueller M, Celik S, Biener M, Vafaie M, Schwoebel K, Wollert KC, Januzzi JL, Katus HA, Giannitsis E (2012) Diagnostic and prognostic performance of a novel high-sensitivity cardiac troponin T assay compared to a contemporary sensitive cardiac troponin I assay in patients with acute coronary syndrome. Clin Res Cardiol 101:837-845
20. Celik S, Giannitsis E, Wollert KC, Schwobel K, Lossnitzer D, Hilbel T, Lehrke S, Zdunek D, Hess A, Januzzi JL, Katus HA (2011) Cardiac troponin T concentrations above the 99th percentile value as measured by a new high-sensitivity assay predict long-term prognosis in patients with acute coronary syndromes undergoing routine early invasive strategy. Clin Res Cardiol 100:1077-1085
21. Beciani M, Tedesco A, Violante A, Cipriani S, Azzarito M, Sturniolo A, Splendiani G (2003) Cardiac troponin I (2nd generation assay) in chronic haemodialysis patients: prevalence and prognostic value. Nephrol Dial Transplant 18:942-946
22. Kumar N, Michelis MF, DeVita MV, Panagopoulos G, Rosenstock JL (2011) Troponin I levels in asymptomatic patients on haemodialysis using a high-sensitivity assay. Nephrol Dial Transplant 26:665-670
23. Ritz E, Rambausek M, Mall G, Ruffmann K, Mandelbaum A (1990) Cardiac changes in uraemia and their possible relationship to cardiovascular instability on dialysis. Nephrol Dial Transplant 5(Suppl 1):93-97
24. McIntyre CW (2009) Effects of hemodialysis on cardiac function. Kidney Int 76:371-375
25. Assa S, Dasselaar JJ, Slart RH, de Jong PE, Voors AA, Tio RA, Franssen CF (2012) Comparison of cardiac positron emission tomography perfusion defects during stress induced by hemodialysis versus adenosine. Am J Kidney Dis 59:862-864
26. Burton JO, Jefferies HJ, Selby NM, McIntyre CW (2009) Hemodialysis-induced cardiac injury: determinants and associated outcomes. Clin J Am Soc Nephrol 4:914-920
27. Assa S, Hummel YM, Voors AA, Kuipers J, Westerhuis R, de Jong PE, Franssen CF (2012) Hemodialysis-induced regional left ventricular systolic dysfunction: prevalence, patient and dialysis treatment-related factors, and prognostic significance. Clin J Am Soc Nephrol 7:1615-1623
28. Apple FS, Pearce LA, Smith SW, Kaczmarek JM, Murakami MM (2009) Role of monitoring changes in sensitive cardiac troponin I assay results for early diagnosis of myocardial infarction and prediction of risk of adverse events. Clin Chem 55:930-937