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Volumn 54, Issue 4, 2013, Pages 854-864

Pharmacogenomic assessment of outcomes of pemetrexed-treated patients with adenocarcinoma of the lung

Author keywords

Lung neoplasms; Pemetrexed; Polymorphism

Indexed keywords

DIHYDROFOLATE REDUCTASE; PEMETREXED; THYMIDYLATE SYNTHASE;

EID: 84878228603     PISSN: 05135796     EISSN: None     Source Type: Journal    
DOI: 10.3349/ymj.2013.54.4.854     Document Type: Article
Times cited : (17)

References (22)
  • 1
    • 0035352581 scopus 로고    scopus 로고
    • Pemetrexed disodium, a novel antifolate with multiple targets
    • Curtin NJ, Hughes AN. Pemetrexed disodium, a novel antifolate with multiple targets. Lancet Oncol 2001;2:298-306.
    • (2001) Lancet Oncol , vol.2 , pp. 298-306
    • Curtin, N.J.1    Hughes, A.N.2
  • 2
    • 3042575322 scopus 로고    scopus 로고
    • Pemetrexed (ALIMTA), a novel multitargeted antineoplastic agent
    • Adjei AA. Pemetrexed (ALIMTA), a novel multitargeted antineoplastic agent. Clin Cancer Res 2004;10(12 Pt 2):4276s-80s.
    • (2004) Clin Cancer Res , vol.10 , Issue.12 PART 2
    • Adjei, A.A.1
  • 3
  • 4
    • 14944380124 scopus 로고    scopus 로고
    • Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphism in normal tissue as predictors of fluorouracil sensitivity
    • Jakobsen A, Nielsen JN, Gyldenkerne N, Lindeberg J. Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphism in normal tissue as predictors of fluorouracil sensitivity. J Clin Oncol 2005;23:1365-9.
    • (2005) J Clin Oncol , vol.23 , pp. 1365-1369
    • Jakobsen, A.1    Nielsen, J.N.2    Gyldenkerne, N.3    Lindeberg, J.4
  • 5
    • 4444376725 scopus 로고    scopus 로고
    • Polyglutamation of methotrexate with common polymorphisms in reduced folate carrier, aminoimidazole carboxamide ribonucleotide transformylase, and thymidylate synthase are associated with methotrexate effects in rheumatoid arthritis
    • Dervieux T, Furst D, Lein DO, Capps R, Smith K, Walsh M, et al. Polyglutamation of methotrexate with common polymorphisms in reduced folate carrier, aminoimidazole carboxamide ribonucleotide transformylase, and thymidylate synthase are associated with methotrexate effects in rheumatoid arthritis. Arthritis Rheum 2004;50:2766-74.
    • (2004) Arthritis Rheum , vol.50 , pp. 2766-2774
    • Dervieux, T.1    Furst, D.2    Lein, D.O.3    Capps, R.4    Smith, K.5    Walsh, M.6
  • 6
    • 4644349995 scopus 로고    scopus 로고
    • Methotrexate related adverse effects in patients with rheumatoid arthritis are associated with the A1298C polymorphism of the MTHFR gene
    • Berkun Y, Levartovsky D, Rubinow A, Orbach H, Aamar S, Grenader T, et al. Methotrexate related adverse effects in patients with rheumatoid arthritis are associated with the A1298C polymorphism of the MTHFR gene. Ann Rheum Dis 2004;63:1227-31.
    • (2004) Ann Rheum Dis , vol.63 , pp. 1227-1231
    • Berkun, Y.1    Levartovsky, D.2    Rubinow, A.3    Orbach, H.4    Aamar, S.5    Grenader, T.6
  • 7
    • 0032914341 scopus 로고    scopus 로고
    • Biological activity of the multitargeted antifolate, MTA (LY231514), in human cell lines with different resistance mechanisms to antifolate drugs
    • Schultz RM, Chen VJ, Bewley JR, Roberts EF, Shih C, Dempsey JA. Biological activity of the multitargeted antifolate, MTA (LY231514), in human cell lines with different resistance mechanisms to antifolate drugs. Semin Oncol 1999;26(2 Suppl 6):68-73.
    • (1999) Semin Oncol , vol.26 , Issue.2 SUPPL. 6 , pp. 68-73
    • Schultz, R.M.1    Chen, V.J.2    Bewley, J.R.3    Roberts, E.F.4    Shih, C.5    Dempsey, J.A.6
  • 8
    • 0041695633 scopus 로고    scopus 로고
    • Induction of resistance to the multitargeted antifolate Pemetrexed (ALIMTA) in WiDr human colon cancer cells is associated with thymidylate synthase overexpression
    • Sigmond J, Backus HH, Wouters D, Temmink OH, Jansen G, Peters GJ. Induction of resistance to the multitargeted antifolate Pemetrexed (ALIMTA) in WiDr human colon cancer cells is associated with thymidylate synthase overexpression. Biochem Pharmacol 2003;66:431-8.
    • (2003) Biochem Pharmacol , vol.66 , pp. 431-438
    • Sigmond, J.1    Backus, H.H.2    Wouters, D.3    Temmink, O.H.4    Jansen, G.5    Peters, G.J.6
  • 9
    • 65349091355 scopus 로고    scopus 로고
    • Randomized phase II and pharmacogenetic study of pemetrexed compared with pemetrexed plus carboplatin in pretreated patients with advanced non-small-cell lung cancer
    • Smit EF, Burgers SA, Biesma B, Smit HJ, Eppinga P, Dingemans AM, et al. Randomized phase II and pharmacogenetic study of pemetrexed compared with pemetrexed plus carboplatin in pretreated patients with advanced non-small-cell lung cancer. J Clin Oncol 2009;27:2038-45.
    • (2009) J Clin Oncol , vol.27 , pp. 2038-2045
    • Smit, E.F.1    Burgers, S.A.2    Biesma, B.3    Smit, H.J.4    Eppinga, P.5    Dingemans, A.M.6
  • 10
    • 0036265638 scopus 로고    scopus 로고
    • Pharmacogenetics and folate metabolism--a promising direction
    • Ulrich CM, Robien K, Sparks R. Pharmacogenetics and folate metabolism--a promising direction. Pharmacogenomics 2002;3: 299-313.
    • (2002) Pharmacogenomics , vol.3 , pp. 299-313
    • Ulrich, C.M.1    Robien, K.2    Sparks, R.3
  • 12
    • 0034594628 scopus 로고    scopus 로고
    • New guidelines to evaluate the response to treatment in solid tumors
    • European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada
    • Therasse P, Arbuck SG, Eisenhauer EA, Wanders J, Kaplan RS, Rubinstein L, et al. New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst 2000;92:205-16.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 205-216
    • Therasse, P.1    Arbuck, S.G.2    Eisenhauer, E.A.3    Wanders, J.4    Kaplan, R.S.5    Rubinstein, L.6
  • 14
    • 33847611097 scopus 로고    scopus 로고
    • Involvement of gene polymorphisms of thymidylate synthase in gene expression, protein activity and anticancer drug cytotoxicity using the NCI-60 panel
    • Nief N, Le Morvan V, Robert J. Involvement of gene polymorphisms of thymidylate synthase in gene expression, protein activity and anticancer drug cytotoxicity using the NCI-60 panel. Eur J Cancer 2007;43:955-62.
    • (2007) Eur J Cancer , vol.43 , pp. 955-962
    • Nief, N.1    Le Morvan, V.2    Robert, J.3
  • 15
    • 33749587054 scopus 로고    scopus 로고
    • Squamous cell carcinoma of the lung compared with other histotypes shows higher messenger RNA and protein levels for thymidylate synthase
    • Ceppi P, Volante M, Saviozzi S, Rapa I, Novello S, Cambieri A, et al. Squamous cell carcinoma of the lung compared with other histotypes shows higher messenger RNA and protein levels for thymidylate synthase. Cancer 2006;107:1589-96.
    • (2006) Cancer , vol.107 , pp. 1589-1596
    • Ceppi, P.1    Volante, M.2    Saviozzi, S.3    Rapa, I.4    Novello, S.5    Cambieri, A.6
  • 16
    • 49049089802 scopus 로고    scopus 로고
    • Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer
    • Scagliotti GV, Parikh P, von Pawel J, Biesma B, Vansteenkiste J, Manegold C, et al. Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer. J Clin Oncol 2008;26:3543-51.
    • (2008) J Clin Oncol , vol.26 , pp. 3543-3551
    • Scagliotti, G.V.1    Parikh, P.2    von Pawel, J.3    Biesma, B.4    Vansteenkiste, J.5    Manegold, C.6
  • 17
    • 43549120811 scopus 로고    scopus 로고
    • DNA variants in the dihydrofolate reductase gene and outcome in childhood ALL
    • Dulucq S, St-Onge G, Gagné V, Ansari M, Sinnett D, Labuda D, et al. DNA variants in the dihydrofolate reductase gene and outcome in childhood ALL. Blood 2008;111:3692-700.
    • (2008) Blood , vol.111 , pp. 3692-3700
    • Dulucq, S.1    St-Onge, G.2    Gagné, V.3    Ansari, M.4    Sinnett, D.5    Labuda, D.6
  • 18
    • 77955092334 scopus 로고    scopus 로고
    • Genetic determinants of pemetrexed responsiveness and nonresponsiveness in non-small cell lung cancer cells
    • Wu MF, Hsiao YM, Huang CF, Huang YH, Yang WJ, Chan HW, et al. Genetic determinants of pemetrexed responsiveness and nonresponsiveness in non-small cell lung cancer cells. J Thorac Oncol 2010;5:1143-51.
    • (2010) J Thorac Oncol , vol.5 , pp. 1143-1151
    • Wu, M.F.1    Hsiao, Y.M.2    Huang, C.F.3    Huang, Y.H.4    Yang, W.J.5    Chan, H.W.6
  • 19
    • 78650233431 scopus 로고    scopus 로고
    • TS, DHFR and GARFT expression in non-squamous cell carcinoma of NSCLC and malignant pleural mesothelioma patients treated with pemetrexed
    • Uramoto H, Onitsuka T, Shimokawa H, Hanagiri T. TS, DHFR and GARFT expression in non-squamous cell carcinoma of NSCLC and malignant pleural mesothelioma patients treated with pemetrexed. Anticancer Res 2010;30:4309-15.
    • (2010) Anticancer Res , vol.30 , pp. 4309-4315
    • Uramoto, H.1    Onitsuka, T.2    Shimokawa, H.3    Hanagiri, T.4
  • 20
    • 30444442971 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase 677C/T gene polymorphism, gastric cancer susceptibility and genomic DNA hypomethylation in an at-risk Italian population
    • Graziano F, Kawakami K, Ruzzo A, Watanabe G, Santini D, Pizzagalli F, et al. Methylenetetrahydrofolate reductase 677C/T gene polymorphism, gastric cancer susceptibility and genomic DNA hypomethylation in an at-risk Italian population. Int J Cancer 2006;118:628-32.
    • (2006) Int J Cancer , vol.118 , pp. 628-632
    • Graziano, F.1    Kawakami, K.2    Ruzzo, A.3    Watanabe, G.4    Santini, D.5    Pizzagalli, F.6
  • 21
    • 0036278536 scopus 로고    scopus 로고
    • A polymorphism in the methylenetetrahydrofolate reductase gene predisposes to colorectal cancers with microsatellite instability
    • Shannon B, Gnanasampanthan S, Beilby J, Iacopetta B. A polymorphism in the methylenetetrahydrofolate reductase gene predisposes to colorectal cancers with microsatellite instability. Gut 2002;50:520-4.
    • (2002) Gut , vol.50 , pp. 520-524
    • Shannon, B.1    Gnanasampanthan, S.2    Beilby, J.3    Iacopetta, B.4
  • 22
    • 56349130046 scopus 로고    scopus 로고
    • Meta-analyses of the methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and risk of head and neck and lung cancer
    • Boccia S, Boffetta P, Brennan P, Ricciardi G, Gianfagna F, Matsuo K, et al. Meta-analyses of the methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and risk of head and neck and lung cancer. Cancer Lett 2009;273:55-61.
    • (2009) Cancer Lett , vol.273 , pp. 55-61
    • Boccia, S.1    Boffetta, P.2    Brennan, P.3    Ricciardi, G.4    Gianfagna, F.5    Matsuo, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.