A novel protoapigenone analog RY10-4 induces breast cancer MCF-7 cell death through autophagy via the Akt/mTOR pathway

Toxicology and Applied Pharmacology

Volumn 270, Issue 2, 2013, Pages 122-128

  Zhang, Xuenong ^a   Wei, Han ^a   Liu, Ziwei ^a   Yuan, Qianying ^a   Wei, Anhua ^a   Shi, Du ^a   Yang, Xian ^a   Ruan, Jinlan ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Autophagy; Breast cancer; MTOR; Protoapigenone; RY10 4

Indexed keywords

CELL PROTEIN; DANSYLCADAVERINE; FLAVONOID; LIGHT CHAIN 3 PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN KINASE B; PROTEIN P62; PROTEIN P70S6K; PROTOAPIGENONE; RY 104; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; AUTOPHAGY; BREAST CANCER; CELL DEATH; CELL STRAIN MCF 7; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DESIGN; FEMALE; GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MICROTUBULE; PROTEIN ANALYSIS; STAINING; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; APOPTOSIS; AUTOPHAGY; BLOTTING, WESTERN; BREAST NEOPLASMS; CELL SURVIVAL; FEMALE; HUMANS; MCF-7 CELLS; MICROSCOPY, ELECTRON, TRANSMISSION; PROTO-ONCOGENE PROTEINS C-AKT; PYRONES; TOR SERINE-THREONINE KINASES;

EID: 84878225538     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2013.04.011     Document Type: Article

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