-
2
-
-
0033576811
-
Disseminated intravascular coagulation
-
DOI 10.1056/NEJM199908193410807
-
Levi M, ten Cate H. Disseminated intravascular coagulation. N Engl J Med 1999;341:586-92. (Pubitemid 29384168)
-
(1999)
New England Journal of Medicine
, vol.341
, Issue.8
, pp. 586-592
-
-
Levi, M.1
Ten, C.H.2
-
3
-
-
77949303559
-
The coagulant response in sepsis and inflammation
-
Levi M. The coagulant response in sepsis and inflammation. Hamostaseologie 2010;30:10-6.
-
(2010)
Hamostaseologie
, vol.30
, pp. 10-16
-
-
Levi, M.1
-
4
-
-
77954742078
-
Platelet-vessel wall interaction in health and disease
-
Lowenberg EC, Meijers JC, Levi M. Platelet-vessel wall interaction in health and disease. Neth J Med 2010;68:242-51.
-
(2010)
Neth J Med
, vol.68
, pp. 242-251
-
-
Lowenberg, E.C.1
Meijers, J.C.2
Levi, M.3
-
5
-
-
1242266005
-
Multiple coagulative defects in a patient with the Waterhouse- Friderichsen syndrome
-
Ratnoff OD, Nebehay WG. Multiple coagulative defects in a patient with the Waterhouse-Friderichsen syndrome. Ann Intern Med 1962;56:627.
-
(1962)
Ann Intern Med
, vol.56
, pp. 627
-
-
Ratnoff, O.D.1
Nebehay, W.G.2
-
7
-
-
0023096623
-
The regulation of natural anticoagulant pathways
-
Esmon CT. The regulation of natural anticoagulant pathways. Science 1987;235:1348-52. (Pubitemid 17041653)
-
(1987)
Science
, vol.235
, Issue.4794
, pp. 1348-1352
-
-
Esmon, C.T.1
-
8
-
-
0029895009
-
TAFI, or plasma procarboxypeptidase B, couples the coagulation and fibrinolytic cascades through the thrombin-thrombomodulin complex
-
DOI 10.1074/jbc.271.28.16603
-
Bajzar L, Morser J, Nesheim M. TAFI, or plasma procarboxypeptidase B, couples the coagulation and fibrinolytic cascades through the thrombin-thrombomodulin complex. J Biol Chem 1996;271:16603-8. (Pubitemid 26239017)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.28
, pp. 16603-16608
-
-
Bajzar, L.1
Morser, J.2
Nesheim, M.3
-
9
-
-
0028855106
-
Coagulation activation and tissue necrosis in meningococcal septic shock: Severely reduced protein C levels predict a high mortality
-
Fijnvandraat K, Derkx B, Peters M, Bijlmer R, Sturk A, Prins MH et al. Coagulation activation and tissue necrosis in meningococcal septic shock: severely reduced protein C levels predict a high mortality. Thromb Haemost 1995;73:15-20.
-
(1995)
Thromb Haemost
, vol.73
, pp. 15-20
-
-
Fijnvandraat, K.1
Derkx, B.2
Peters, M.3
Bijlmer, R.4
Sturk, A.5
Prins, M.H.6
-
10
-
-
0024419991
-
The quantitative association of plasma endotoxin, antithrombin, protein C, extrinsic pathway inhibitor and fibrinopeptide A in systemic meningococcal disease
-
DOI 10.1016/0049-3848(89)90054-6
-
Brandrzaeg P, Sandset PM, Joo GB, Ovstebo R, Abildgaard U, Kierulf P. The quantitative association of plasma endotoxin, antithrombin, protein C, extrinsic pathway inhibitor and fibrinopeptide A in systemic meningococcal disease. Thromb Res 1989;55:459-70. (Pubitemid 19215683)
-
(1989)
Thrombosis Research
, vol.55
, Issue.4
, pp. 459-470
-
-
Brandtzaeg, P.1
Sandset, P.M.2
Joo, G.B.3
Ovstebo, R.4
Abildgaard, U.5
Kierulf, P.6
-
11
-
-
0038115187
-
Aggravation of endotoxin-induced disseminated intravascular coagulation and cytokine activation in heterozygous protein-C-deficient mice
-
Levi M, Dorffler-Melly J, Reitsma PH, Buller HR, Florquin S, van der Poll T et al. Aggravation of endotoxin-induced disseminated intravascular coagulation and cytokine activation in heterozygous protein C deficient mice. Blood 2003;101:4823-7. (Pubitemid 36857741)
-
(2003)
Blood
, vol.101
, Issue.12
, pp. 4823-4827
-
-
Levi, M.1
Dorffler-Melly, J.2
Reitsma, P.3
Buller, H.4
Florquin, S.5
Van Der, P.T.6
Carmeliet, P.7
-
12
-
-
0028103281
-
Differential regulation of alpha and beta chains of C4b-binding protein during acute-phase response resulting in stable plasma levels of free anticoagulant protein S
-
Garcia de Frutos P, Alim RI, Hardig Y, Zoller B, Dahlback B. Differential regulation of alpha and beta chains of C4b-binding protein during acute-phase response resulting in stable plasma levels of free anticoagulant protein S. Blood 1994;84:815-22.
-
(1994)
Blood
, vol.84
, pp. 815-822
-
-
Garcia De Frutos, P.1
Alim, R.I.2
Hardig, Y.3
Zoller, B.4
Dahlback, B.5
-
13
-
-
0025835094
-
C4b-binding protein exacerbates the host response to Escherichia coli
-
Taylor F, Chang A, Ferrell G, Mather T, Catlett R, Blick K et al. C4b-binding protein exacerbates the host response to Escherichia coli. Blood 1991;78:357-63.
-
(1991)
Blood
, vol.78
, pp. 357-363
-
-
Taylor, F.1
Chang, A.2
Ferrell, G.3
Mather, T.4
Catlett, R.5
Blick, K.6
-
14
-
-
0029156005
-
Role of free protein S and C4b binding protein in regulating the coagulant response to Escherichia coli
-
Taylor FBJ, Dahlback B, Chang AC, Lockhart MS, Hatanaka K, Peer G et al. Role of free protein S and C4b binding protein in regulating the coagulant response to Escherichia coli. Blood 1995;86:2642-52.
-
(1995)
Blood
, vol.86
, pp. 2642-2652
-
-
Taylor, F.B.J.1
Dahlback, B.2
Chang, A.C.3
Lockhart, M.S.4
Hatanaka, K.5
Peer, G.6
-
15
-
-
84875964557
-
The lectin-like domain of thrombomodulin hampers host defense in pneumococcal pneumonia
-
In press
-
Schouten M, de Boer JD, van't Veer C, Roelofs JJ, Meijers JC, Levi M et al. The lectin-like domain of thrombomodulin hampers host defense in pneumococcal pneumonia. Eur Respir J 2012 [In press].
-
(2012)
Eur Respir J
-
-
Schouten, M.1
De Boer, J.D.2
Van't Veer, C.3
Roelofs, J.J.4
Meijers, J.C.5
Levi, M.6
-
16
-
-
84857860942
-
Thrombomodulin and its role in inflammation
-
Conway EM. Thrombomodulin and its role in inflammation. Semin Immunopathol 2012;34:107-25.
-
(2012)
Semin Immunopathol
, vol.34
, pp. 107-125
-
-
Conway, E.M.1
-
17
-
-
43349096795
-
Inflammation, endothelium, and coagulation in sepsis
-
DOI 10.1189/jlb.0607373
-
Schouten M, Wiersinga WJ, Levi M, van der Poll T. Inflammation, endothelium, and coagulation in sepsis. J Leukoc Biol 2008;83:536-45. (Pubitemid 351966862)
-
(2008)
Journal of Leukocyte Biology
, vol.83
, Issue.3
, pp. 536-545
-
-
Schouten, M.1
Wiersinga, W.J.2
Levi, M.3
Van Der, P.T.4
-
18
-
-
0036719236
-
New mechanisms for vascular control of inflammation mediated by natural anticoagulant proteins
-
DOI 10.1084/jem.20021088
-
Esmon CT. New mechanisms for vascular control of inflammation mediated by natural anticoagulant proteins. J Exp Med 2002;196:561-4. (Pubitemid 35024435)
-
(2002)
Journal of Experimental Medicine
, vol.196
, Issue.5
, pp. 561-564
-
-
Esmon, C.T.1
-
19
-
-
0024396997
-
The last three consecutive epidermal growth factor-like structures of human thrombomodulin comprise the minimum functional domain for protein C-activating cofactor activity and anticoagulant activity
-
Zushi M, Gomi K, Yamamoto S, Maruyama I, Hayashi T, Suzuki K. The last three consecutive epidermal growth factor-like structures of human thrombomodulin comprise the minimum functional domain for protein C-activating cofactor activity and anticoagulant activity. J Biol Chem 1989;264:10351-3. (Pubitemid 19161593)
-
(1989)
Journal of Biological Chemistry
, vol.264
, Issue.18
, pp. 10351-10353
-
-
Zushi, M.1
Gomi, K.2
Yamamoto, S.3
Maruyama, I.4
Hayashi, T.5
Suzuki, K.6
-
20
-
-
0036719075
-
The lectin-like domain of thrombomodulin confers protection from neutrophil-mediated tissue damage by suppressing adhesion molecule expression via nuclear factor kappaB and mitogen-activated protein kinase pathways
-
Conway EM, Van de WM, Pollefeyt S, Jurk K, Van Aken H, De Vriese A et al. The lectin-like domain of thrombomodulin confers protection from neutrophil-mediated tissue damage by suppressing adhesion molecule expression via nuclear factor kappaB and mitogen-activated protein kinase pathways. J Exp Med 2002;196:565-77.
-
(2002)
J Exp Med
, vol.196
, pp. 565-577
-
-
Conway, E.M.1
Van De, W.M.2
Pollefeyt, S.3
Jurk, K.4
Van Aken, H.5
De Vriese, A.6
-
21
-
-
84857130776
-
Thrombomodulin links coagulation to inflammation and immunity
-
Morser J. Thrombomodulin links coagulation to inflammation and immunity. Curr Drug Targets 2012;13:421-31.
-
(2012)
Curr Drug Targets
, vol.13
, pp. 421-431
-
-
Morser, J.1
-
22
-
-
0022601049
-
Modulation of endothelial cell hemostatic properties by tumor necrosis factor
-
Nawroth PP, Stern DM. Modulation of endothelial cell hemostatic properties by tumor necrosis factor. J Exp Med 1986;163:740-5. (Pubitemid 16141974)
-
(1986)
Journal of Experimental Medicine
, vol.163
, Issue.3
, pp. 740-745
-
-
Nawroth, P.P.1
Stern, D.M.2
-
23
-
-
0035833529
-
Dysfunction of endothelial protein C activation in severe meningococcal sepsis
-
Faust SN, Levin M, Harrison OB, Goldin RD, Lockhart MS, Kondaveeti S et al. Dysfunction of endothelial protein C activation in severe meningococcal sepsis. N Engl J Med 2001;345:408-16345: 408-416.
-
(2001)
N Engl J Med
, vol.345
-
-
Faust, S.N.1
Levin, M.2
Harrison, O.B.3
Goldin, R.D.4
Lockhart, M.S.5
Kondaveeti, S.6
-
24
-
-
55049107958
-
The role of natural anticoagulants in the pathogenesis and management of systemic activation of coagulation and inflammation in critically ill patients
-
Levi M, van der Poll T. The role of natural anticoagulants in the pathogenesis and management of systemic activation of coagulation and inflammation in critically ill patients. Semin Thromb Hemost 2008;34:459-68.
-
(2008)
Semin Thromb Hemost
, vol.34
, pp. 459-468
-
-
Levi, M.1
Van Der Poll, T.2
-
25
-
-
80051768207
-
Model-based analysis of covariate effects on population pharmacokinetics of thrombomodulin alfa in patients with disseminated intravascular coagulation and normal subjects
-
Tsuruta K, Yamada Y, Serada M, Tanigawara Y. Model-based analysis of covariate effects on population pharmacokinetics of thrombomodulin alfa in patients with disseminated intravascular coagulation and normal subjects. J Clin Pharmacol 2011;51:1276-85.
-
(2011)
J Clin Pharmacol
, vol.51
, pp. 1276-1285
-
-
Tsuruta, K.1
Yamada, Y.2
Serada, M.3
Tanigawara, Y.4
-
26
-
-
33845513582
-
Efficacy and safety of recombinant human soluble thrombomodulin (ART-123) in disseminated intravascular coagulation: Results of a phase III, randomized, double-blind clinical trial
-
DOI 10.1111/j.1538-7836.2006.02267.x
-
Saito H, Maruyama I, Shimazaki S, Yamamoto Y, Aikawa N, Ohno R et al. Efficacy and safety of recombinant human soluble thrombomodulin (ART-123) in disseminated intravascular coagulation: results of a phase III, randomized, double-blind clinical trial. J Thromb Haemost 2007;5:31-41. (Pubitemid 44921064)
-
(2007)
Journal of Thrombosis and Haemostasis
, vol.5
, Issue.1
, pp. 31-41
-
-
Saito, H.1
Maruyama, I.2
Shimazaki, S.3
Yamamoto, Y.4
Aikawa, N.5
Ohno, R.6
Hirayama, A.7
Matsuda, T.8
Asakura, H.9
Nakashima, M.10
Aoki, N.11
-
27
-
-
79961081848
-
Thrombomodulin alfa in the treatment of infectious patients complicated by disseminated intravascular coagulation: Subanalysis from the phase 3 trial
-
Aikawa N, Shimazaki S, Yamamoto Y, Saito H, Maruyama I, Ohno R et al. Thrombomodulin alfa in the treatment of infectious patients complicated by disseminated intravascular coagulation: subanalysis from the phase 3 trial. Shock 2011;35:349-54.
-
(2011)
Shock
, vol.35
, pp. 349-354
-
-
Aikawa, N.1
Shimazaki, S.2
Yamamoto, Y.3
Saito, H.4
Maruyama, I.5
Ohno, R.6
-
28
-
-
84864558977
-
Recombinant human soluble thrombomodulin improves mortality and respiratory dysfunction in patients with severe sepsis
-
Ogawa Y, Yamakawa K, Ogura H, Kiguchi T, Mohri T, Nakamori Y et al. Recombinant human soluble thrombomodulin improves mortality and respiratory dysfunction in patients with severe sepsis. J Trauma Acute Care Surg 2012;72:1150-7.
-
(2012)
J Trauma Acute Care Surg
, vol.72
, pp. 1150-1157
-
-
Ogawa, Y.1
Yamakawa, K.2
Ogura, H.3
Kiguchi, T.4
Mohri, T.5
Nakamori, Y.6
-
29
-
-
84861460182
-
Pharmacokinetics and pharmacodynamics of recombinant soluble thrombomodulin in disseminated intravascular coagulation patients with renal impairment
-
Hayakawa M, Yamamoto H, Honma T, Mukai N, Higashiyama A, Sugano M et al. Pharmacokinetics and pharmacodynamics of recombinant soluble thrombomodulin in disseminated intravascular coagulation patients with renal impairment. Shock 2012;37:569-73.
-
(2012)
Shock
, vol.37
, pp. 569-573
-
-
Hayakawa, M.1
Yamamoto, H.2
Honma, T.3
Mukai, N.4
Higashiyama, A.5
Sugano, M.6
|