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Volumn 37, Issue 6, 2012, Pages 569-573

Pharmacokinetics and pharmacodynamics of recombinant soluble thrombomodulin in disseminated intravascular coagulation patients with renal impairment

Author keywords

clearance; Disseminated intravascular coagulation; protein C; prothrombinase activity; renal dysfunction; thrombomodulin

Indexed keywords

BLOOD CLOTTING FACTOR 10A; RECOMBINANT THROMBOMODULIN;

EID: 84861460182     PISSN: 10732322     EISSN: 15400514     Source Type: Journal    
DOI: 10.1097/SHK.0b013e318252bc82     Document Type: Article
Times cited : (11)

References (21)
  • 1
    • 33644801469 scopus 로고    scopus 로고
    • The interactions between inflammation and coagulation
    • DOI 10.1111/j.1365-2141.2005.05753.x
    • Esmon CT: The interactions between inflammation and coagulation. Br J Haematol 131(4):417-430, 2005. (Pubitemid 43899639)
    • (2005) British Journal of Haematology , vol.131 , Issue.4 , pp. 417-430
    • Esmon, C.T.1
  • 2
    • 0031951276 scopus 로고    scopus 로고
    • Pharmacokinetics and safety of a novel recombinant soluble human thrombomodulin, ART-123, in healthy male volunteers
    • Nakashima M, Kanamaru M, Umemura K, Tsuruta K: Pharmacokinetics and safety of a novel recombinant soluble human thrombomodulin, ART-123, in healthy male volunteers. J Clin Pharmacol 38(1):40-44, 1998. (Pubitemid 28086722)
    • (1998) Journal of Clinical Pharmacology , vol.38 , Issue.1 , pp. 40-44
    • Nakashima, M.1    Kanamaru, M.2    Umemura, K.3    Tsuruta, K.4
  • 3
    • 61649088407 scopus 로고    scopus 로고
    • Pharmacokinetics of recombinant human soluble thrombomodulin, thrombomodulin alfa in the rat
    • Tsuruta K, Kodama T, Serada M, Hori K, Inaba A, Miyake T, Kohira T: Pharmacokinetics of recombinant human soluble thrombomodulin, thrombomodulin alfa in the rat. Xenobiotica 39(2):125-134, 2009.
    • (2009) Xenobiotica , vol.39 , Issue.2 , pp. 125-134
    • Tsuruta, K.1    Kodama, T.2    Serada, M.3    Hori, K.4    Inaba, A.5    Miyake, T.6    Kohira, T.7
  • 4
    • 79851496065 scopus 로고    scopus 로고
    • Phase i study of solulin, a novel recombinant soluble human thrombomodulin analogue
    • van Iersel T, Stroissnig H, Giesen P, Wemer J, Wilhelm-Ogunbiyi K: Phase I study of solulin, a novel recombinant soluble human thrombomodulin analogue. Thromb Haemost 105(2):302-312, 2011.
    • (2011) Thromb Haemost , vol.105 , Issue.2 , pp. 302-312
    • Van Iersel, T.1    Stroissnig, H.2    Giesen, P.3    Wemer, J.4    Wilhelm-Ogunbiyi, K.5
  • 6
    • 0028893025 scopus 로고
    • The natural history of the systemic inflammatory response syndrome (SIRS).A prospective study
    • Rangel-Frausto MS, Pittet D, Costigan M, Hwang T, Davis CS, Wenzel RP: The natural history of the systemic inflammatory response syndrome (SIRS). A prospective study. JAMA 273(2):117-123, 1995.
    • (1995) JAMA , vol.273 , Issue.2 , pp. 117-123
    • Rangel-Frausto, M.S.1    Pittet, D.2    Costigan, M.3    Hwang, T.4    Davis, C.S.5    Wenzel, R.P.6
  • 7
    • 0031781668 scopus 로고    scopus 로고
    • A novel recombinant soluble human thrombomodulin, ART-123, activates the protein C pathway in healthy male volunteers
    • Nakashima M, Uematsu T, Umemura K, Maruyama I, Tsuruta K: A novel recombinant soluble human thrombomodulin, ART-123, activates the protein C pathway in healthy male volunteers. J Clin Pharmacol 38(6):540-544, 1998. (Pubitemid 28285229)
    • (1998) Journal of Clinical Pharmacology , vol.38 , Issue.6 , pp. 540-544
    • Nakashima, M.1    Uematsu, T.2    Umemura, K.3    Maruyama, I.4    Tsuruta, K.5
  • 8
    • 37548998584 scopus 로고    scopus 로고
    • Natural history of disseminated intravascular coagulation diagnosed based on the newly established diagnostic criteria for critically ill patients: Results of a multicenter, prospective survey
    • Gando S, Saitoh D, Ogura H, Mayumi T, Koseki K, Ikeda T, Ishikura H, Iba T, Ueyama M, Eguchi Y, et al.: Natural history of disseminated intravascular coagulation diagnosed based on the newly established diagnostic criteria for critically ill patients: results of a multicenter, prospective survey. Crit Care Med 36(1):145-150, 2008.
    • (2008) Crit Care Med , vol.36 , Issue.1 , pp. 145-150
    • Gando, S.1    Saitoh, D.2    Ogura, H.3    Mayumi, T.4    Koseki, K.5    Ikeda, T.6    Ishikura, H.7    Iba, T.8    Ueyama, M.9    Eguchi, Y.10
  • 10
    • 0031735051 scopus 로고    scopus 로고
    • Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: Results of a multicenter, prospective study
    • Vincent JL, de Mendonca A, Cantraine F, Moreno R, Takala J, Suter PM, Sprung CL, Colardyn F, Blecher S: Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: results of a multicenter, prospective study. Working group on Bsepsis-related problems[ of the uropean Society of Intensive Care Medicine. Crit Care Med 26(11): 1793-1800, 1998. (Pubitemid 28527688)
    • (1998) Critical Care Medicine , vol.26 , Issue.11 , pp. 1793-1800
    • Vincent, J.-L.1    De Mendonca, A.2    Cantraine, F.3    Moreno, R.4    Takala, J.5    Suter, P.M.6    Sprung, C.L.7    Colardyn, F.8    Blecher, S.9
  • 11
    • 0026874127 scopus 로고
    • The ACCP/SCCM Consensus Conference Committee: American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis
    • The ACCP/SCCM Consensus Conference Committee: American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 20(6):864-874, 1992.
    • (1992) Crit Care Med , vol.20 , Issue.6 , pp. 864-874
  • 12
    • 84861457805 scopus 로고    scopus 로고
    • US Department of Health and Human Services Food and Drug Administration: Pharmacokinetics in patients with impaired renal function Guidance for Industry Accessed April,4, 2012
    • US Department of Health and Human Services Food and Drug Administration: Pharmacokinetics in patients with impaired renal function. Study design, data analysis, and impact on dosing and labeling. Guidance for Industry 1998. Available at: http://www.fda.gov/downloads/Drugs/ GuidanceComplianceRegulatoryInformation/Guidances/UCM072127.pdf. Accessed April 4, 2012.
    • (1998) Study Design, Data Analysis, and Impact on Dosing and Labeling
  • 13
    • 80051768207 scopus 로고    scopus 로고
    • Model-based analysis of covariate effects on population pharmacokinetics of thrombomodulin alfa in disseminated intravascular coagulation (DIC) patients and normal subjects
    • Tsuruta K, Yamada Y, Serada M, Tanigawara Y: Model-based analysis of covariate effects on population pharmacokinetics of thrombomodulin alfa in disseminated intravascular coagulation (DIC) patients and normal subjects. J Clin Pharmacol 51(9):1276-1285, 2010.
    • (2010) J Clin Pharmacol , vol.51 , Issue.9 , pp. 1276-1285
    • Tsuruta, K.1    Yamada, Y.2    Serada, M.3    Tanigawara, Y.4
  • 15
    • 0031818148 scopus 로고    scopus 로고
    • Serum albumin: Touchstone or totem?
    • DOI 10.1046/j.1365-2044.1998.00438.x
    • Margarson MP, Soni N: Serum albumin: touchstone or totem? Anaesthesia 53(8):789-803, 1998. (Pubitemid 28391386)
    • (1998) Anaesthesia , vol.53 , Issue.8 , pp. 789-803
    • Margarson, M.P.1    Soni, N.2
  • 16
    • 78651241847 scopus 로고    scopus 로고
    • Plasma protein levels are markers of pulmonary vascular permeability and degree of lung injury in critically ill patients with or at risk for acute lung injury/acute respiratory distress syndrome
    • Aman J, van der Heijden M, van Lingen A, Girbes AR, van Nieuw Amerongen GP, van Hinsbergh VW, Groeneveld AB: Plasma protein levels are markers of pulmonary vascular permeability and degree of lung injury in critically ill patients with or at risk for acute lung injury/acute respiratory distress syndrome. Crit Care Med 39(1):89-97, 2011.
    • (2011) Crit Care Med , vol.39 , Issue.1 , pp. 89-97
    • Aman, J.1    Van Der Heijden, M.2    Van Lingen, A.3    Girbes, A.R.4    Van Nieuw Amerongen, G.P.5    Van Hinsbergh, V.W.6    Groeneveld, A.B.7
  • 17
    • 33846219445 scopus 로고    scopus 로고
    • Serum albumin levels anticipate antithrombin III activities before and after antithrombin III agent in critical patients with disseminated intravascular coagulation
    • Aibiki M, Fukuoka N, Umakoshi K, Ohtsubo S, Kikuchi S: Serum albumin levels anticipate antithrombin III activities before and after antithrombin III agent in critical patients with disseminated intravascular coagulation. Shock 27(2):139-144, 2007.
    • (2007) Shock , vol.27 , Issue.2 , pp. 139-144
    • Aibiki, M.1    Fukuoka, N.2    Umakoshi, K.3    Ohtsubo, S.4    Kikuchi, S.5
  • 18
    • 0034523299 scopus 로고    scopus 로고
    • ART-123: Recombinant human soluble thrombomodulin
    • Mohri M: ART-123: recombinant human soluble thrombomodulin. Cardiovascular Drug Reviews 18(4):312-325, 2000.
    • (2000) Cardiovascular Drug Reviews , vol.18 , Issue.4 , pp. 312-325
    • Mohri, M.1
  • 19
    • 33845513582 scopus 로고    scopus 로고
    • Efficacy and safety of recombinant human soluble thrombomodulin (ART-123) in disseminated intravascular coagulation: Results of a phase III, randomized, double-blind clinical trial
    • DOI 10.1111/j.1538-7836.2006.02267.x
    • Saito H, Maruyama I, Shimazaki S, Yamamoto Y, Aikawa N, Ohno R, Hirayama A, Matsuda T, Asakura H, Nakashima M, et al.: Efficacy and safety of recombinant human soluble thrombomodulin (ART-123) in disseminated intravascular coagulation: results of a phase III, randomized, double-blind clinical trial. J Thromb Haemost 5(1):31-41, 2007. (Pubitemid 44921064)
    • (2007) Journal of Thrombosis and Haemostasis , vol.5 , Issue.1 , pp. 31-41
    • Saito, H.1    Maruyama, I.2    Shimazaki, S.3    Yamamoto, Y.4    Aikawa, N.5    Ohno, R.6    Hirayama, A.7    Matsuda, T.8    Asakura, H.9    Nakashima, M.10    Aoki, N.11
  • 20
    • 0032746547 scopus 로고    scopus 로고
    • The inhibitory effect of recombinant human soluble thrombomodulin on initiation and extension of coagulationYa comparison with other anticoagulants
    • Mohri M, Sugimoto E, Sata M, Asano T: The inhibitory effect of recombinant human soluble thrombomodulin on initiation and extension of coagulationYa comparison with other anticoagulants. Thromb Haemost 82(6):1687-1693, 1999.
    • (1999) Thromb Haemost , vol.82 , Issue.6 , pp. 1687-1693
    • Mohri, M.1    Sugimoto, E.2    Sata, M.3    Asano, T.4
  • 21
    • 0036255482 scopus 로고    scopus 로고
    • Markers of endothelial damage in organ dysfunction and sepsis
    • Reinhart K, Bayer O, Brunkhorst F, Meisner M: Markers of endothelial damage in organ dysfunction and sepsis. Crit Care Med 30(5 Suppl): S302-S312, 2002. (Pubitemid 34508007)
    • (2002) Critical Care Medicine , vol.30 , Issue.SUPPL. 5
    • Reinhart, K.1    Bayer, O.2    Brunkhorst, F.3    Meisner, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.