메뉴 건너뛰기




Volumn 6, Issue 1, 2013, Pages 125-132

Network pharmacology-based prediction of the multi-target capabilities of the compounds in Taohong Siwu decoction, and their application in osteoarthritis

Author keywords

Multi target; Network pharmacology; Osteoarthritis; Taohong Siwu decoction

Indexed keywords

AGGRECANASE 1; CHINESE DRUG; COLLAGENASE 3; CYCLIN DEPENDENT KINASE 2; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; GELATINASE B; HEME OXYGENASE 1; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERSTITIAL COLLAGENASE; MACROPHAGE ELASTASE; NEUTROPHIL COLLAGENASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; STROMELYSIN; TAOHONG SIWU DECOCTION; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84878205057     PISSN: 17920981     EISSN: 17921015     Source Type: Journal    
DOI: 10.3892/etm.2013.1106     Document Type: Article
Times cited : (34)

References (33)
  • 2
    • 0036080581 scopus 로고    scopus 로고
    • Effects of SKI306X, a new herbal agent, on proteoglycan degradation in cartilage explant culture and collagenase-induced rabbit osteoarthritis model
    • ChoiJH, ChoiJH, KimDY, YoonJH, YounHY, YiJB, RheeHI, RyuKH, JungK, HanCK, etal: Effects of SKI306X, a new herbal agent, on proteoglycan degradation in cartilage explant culture and collagenase-induced rabbit osteoarthritis model. OsteoarthritisCartilage10: 471-478, 2002.
    • (2002) OsteoarthritisCartilage , vol.10 , pp. 471-478
    • Choi, J.H.1    Choi, J.H.2    Kim, D.Y.3    Yoon, J.H.4    Youn, H.Y.5    Yi, J.B.6    Rhee, H.I.7    Ryu, K.H.8    Jung, K.9    Han, C.K.10
  • 3
    • 84867847575 scopus 로고    scopus 로고
    • Osteoarthritis year 2012 in review: Clinical
    • Hochberg MC: Osteoarthritis year 2012 in review: clinical. Osteoarthritis Cartilage20: 1465-1469, 2012.
    • (2012) Osteoarthritis Cartilage , vol.20 , pp. 1465-1469
    • Hochberg, M.C.1
  • 4
    • 33845762340 scopus 로고    scopus 로고
    • Multi-targettherapeutics: When the whole is greater than the sumof the parts
    • ZimmermannGR, LehárJ and KeithCT: Multi-targettherapeutics: when the whole is greater than the sumof the parts. Drug Discov Today12: 34-42, 2007.
    • (2007) Drug Discov Today , vol.12 , pp. 34-42
    • Zimmermann, G.R.1    Lehár, J.2    Keith, C.T.3
  • 5
    • 55549101279 scopus 로고    scopus 로고
    • Finding multiple target optimal intervention in disease-related molecular network
    • YangK, BaiH, OuyangQ, LaiL and TangC: Finding multiple target optimal intervention in disease-related molecular network. Mol Syst Biol4: 228, 2008.
    • (2008) Mol Syst Biol , vol.4 , pp. 228
    • Yang, K.1    Bai, H.2    Ouyang, Q.3    Lai, L.4    Tang, C.5
  • 6
    • 27144443099 scopus 로고    scopus 로고
    • Drug discovery: Playing dirty
    • Frantz S: Drug discovery: playing dirty. Nature437: 942-943, 2005.
    • (2005) Nature , vol.437 , pp. 942-943
    • Frantz, S.1
  • 7
    • 84877271003 scopus 로고    scopus 로고
    • Computational simulation of multi-target research on the material basis of Caulis sinomenii in treating osteoarthritis
    • (In Chinese)
    • ZhengCS, XuXJ and YeHZ: Computational simulation of multi-target research on the material basis of Caulis sinomenii in treating osteoarthritis. Zhongguo Zhong Xi Yi Jie He Za Zhi32: 375-379, 2012 (In Chinese).
    • (2012) Zhongguo Zhong Xi Yi Jie He Za Zhi , vol.32 , pp. 375-379
    • Zheng, C.S.1    Xu, X.J.2    Ye, H.Z.3
  • 10
    • 84878181446 scopus 로고    scopus 로고
    • The effects of modified Taohong Siwu Tang on MMP-1 and TIMP-1 in articular cartilage of the rats with KOA
    • (In Chinese)
    • LiN, SongM, SongZJ and XieXW: The effects of modified Taohong Siwu Tang on MMP-1 and TIMP-1 in articular cartilage of the rats with KOA. Journal of Gansu College of Traditional Chinese Medicine26(6): 12-14, 2009 (In Chinese).
    • (2009) Journal of Gansu College of Traditional Chinese Medicine , vol.26 , Issue.6 , pp. 12-14
    • Li, N.1    Song, M.2    Song, Z.J.3    Xie, X.W.4
  • 11
    • 84878168319 scopus 로고    scopus 로고
    • Effects of Taohongsiwu decoction and Simiao decoction on the expressions of interleukin-1β and interleukin-6 in rat knee osteoarthritis
    • (In Chinese)
    • LiN, XieXW and SongM: Effects of Taohongsiwu decoction and Simiao decoction on the expressions of interleukin-1β and interleukin-6 in rat knee osteoarthritis. Journal of Lanzhou University (Medical Sciences) 35(2): 24-26, 30, 2009 (In Chinese).
    • (2009) Journal of Lanzhou University (Medical Sciences) , vol.35 , Issue.2
    • Li, N.1    Xie, X.W.2    Song, M.3
  • 12
    • 84865321882 scopus 로고    scopus 로고
    • Network pharmacology: New opportunity for the modernization of traditional Chinese medicine
    • (In Chinese)
    • LiuZH and SunXB: Network pharmacology: new opportunity for the modernization of traditional Chinese medicine. Yao Xue Xue Bao47: 696-703, 2012 (In Chinese).
    • (2012) Yao Xue Xue Bao , vol.47 , pp. 696-703
    • Liu, Z.H.1    Sun, X.B.2
  • 13
    • 80052088034 scopus 로고    scopus 로고
    • Drug-target network and polypharmacology studies of a Traditional Chinese Medicine for typeII diabetes mellitus
    • GuJ, ZhangH, ChenL, XuS, YuanG and XuX. Drug-target network and polypharmacology studies of a Traditional Chinese Medicine for typeII diabetes mellitus. Comput Biol Chem35: 293-297, 2011.
    • (2011) Comput Biol Chem , vol.35 , pp. 293-297
    • Gu, J.1    Zhang, H.2    Chen, L.3    Xu, S.4    Yuan, G.5    Xu, X.6
  • 14
    • 84871281143 scopus 로고    scopus 로고
    • Network pharmacology-based prediction of the active ingredients and potential targets of Chinese herbal Radix Curcumae formula for application to cardiovascular disease
    • TaoW, XuX, WangX, LiB, WangY, LiY and YangL: Network pharmacology-based prediction of the active ingredients and potential targets of Chinese herbal Radix Curcumae formula for application to cardiovascular disease. JEthnopharmacol145: 1-10, 2013.
    • (2013) JEthnopharmacol , vol.145 , pp. 1-10
    • Tao, W.1    Xu, X.2    Wang, X.3    Li, B.4    Wang, Y.5    Li, Y.6    Yang, L.7
  • 15
    • 0036557840 scopus 로고    scopus 로고
    • A 3D structure database of components from Chinese traditional medicinal herbs
    • QiaoX, HouT, ZhangW, GuoS and XuX: A 3D structure database of components from Chinese traditional medicinal herbs. J Chem Inf Comput Sci42: 481-489, 2002.
    • (2002) J Chem Inf Comput Sci , vol.42 , pp. 481-489
    • Qiao, X.1    Hou, T.2    Zhang, W.3    Guo, S.4    Xu, X.5
  • 18
    • 84878168031 scopus 로고    scopus 로고
    • Discussion on multi-component and multi-target pattern of Liuweidihuang pill for osteoarthritis based on computer simulation
    • (In Chinese)
    • ZhengCS, YeHZ, CaiLL, ChenJS, WeiLS and LiuXX: Discussion on multi-component and multi-target pattern of Liuweidihuang pill for osteoarthritis based on computer simulation. Zhongyi Zhenggu25: 11-18, 2013 (In Chinese).
    • (2013) Zhongyi Zhenggu , vol.25 , pp. 11-18
    • Zheng, C.S.1    Ye, H.Z.2    Cai, L.L.3    Chen, J.S.4    Wei, L.S.5    Liu, X.X.6
  • 19
    • 84864427901 scopus 로고    scopus 로고
    • Hyaluronan regulates PPARγ and inflammatory responses in IL-1β-stimulated human chondrosarcoma cells, a model for osteoarthritis
    • ChangCC, HsiehMS, LiaoST, ChenYH, ChengCW, HuangPT, LinYF and ChenCH: Hyaluronan regulates PPARγ and inflammatory responses in IL-1β-stimulated human chondrosarcoma cells, a model for osteoarthritis. Carbohydr Polym90: 1168-1175, 2012.
    • (2012) Carbohydr Polym , vol.90 , pp. 1168-1175
    • Chang, C.C.1    Hsieh, M.S.2    Liao, S.T.3    Chen, Y.H.4    Cheng, C.W.5    Huang, P.T.6    Lin, Y.F.7    Chen, C.H.8
  • 20
    • 72649102482 scopus 로고    scopus 로고
    • Comment on 'the matrix metalloproteinases as pharmacological target in osteoarthritis: Statins may be of therapeutic benefit'
    • LiuYP and YuGR: Comment on 'the matrix metalloproteinases as pharmacological target in osteoarthritis: statins may be of therapeutic benefit'. Med Hypotheses74: 394-395, 2010.
    • (2010) Med Hypotheses , vol.74 , pp. 394-395
    • Liu, Y.P.1    Yu, G.R.2
  • 22
    • 79551587720 scopus 로고    scopus 로고
    • Cytoscape 2.8: New features for data integration and network visualization
    • SmootME, OnoK, RuscheinskiJ, WangPL and IdekerT: Cytoscape 2.8: new features for data integration and network visualization. Bioinformatics27: 431-432, 2011.
    • (2011) Bioinformatics , vol.27 , pp. 431-432
    • Smoot, M.E.1    Ono, K.2    Ruscheinski, J.3    Wang, P.L.4    Ideker, T.5
  • 23
    • 11144341956 scopus 로고    scopus 로고
    • Chemical space and biology
    • Dobson CM: Chemical space and biology. Nature432: 824-828, 2004.
    • (2004) Nature , vol.432 , pp. 824-828
    • Dobson, C.M.1
  • 24
    • 0035289779 scopus 로고    scopus 로고
    • Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
    • LipinskiCA, LombardoF, DominyBW and FeeneyPJ: Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv Drug Deliv Rev46: 3-26, 2001
    • (2001) Adv Drug Deliv Rev , vol.46 , pp. 3-26
    • Lipinski, C.A.1    Lombardo, F.2    Dominy, B.W.3    Feeney, P.J.4
  • 25
    • 33845473284 scopus 로고    scopus 로고
    • Effects of angelica and sodium ferulate injection on cartilage degeneration and metabolism of free radicals in rats with osteoarthritis
    • (In Chinese)
    • LiuBX, ChenLB, WangH, QinJ and WangP: Effects of angelica and sodium ferulate injection on cartilage degeneration and metabolism of free radicals in rats with osteoarthritis. Medical Journal of Wuhan University27: 626-628, 2006 (In Chinese).
    • (2006) Medical Journal of Wuhan University , vol.27 , pp. 626-628
    • Liu, B.X.1    Chen, L.B.2    Wang, H.3    Qin, J.4    Wang, P.5
  • 26
    • 84878165631 scopus 로고    scopus 로고
    • Therapeutic effects of angelica and sodium ferulate on experimental osteoarthritis in rats
    • LiuBX, ChenLB, WangH, QinJ and ShangL: Therapeutic effects of angelica and sodium ferulate on experimental osteoarthritis in rats. Orthopedic Journal of China16: 1316-1318, 2008.
    • (2008) Orthopedic Journal of China , vol.16 , pp. 1316-1318
    • Liu, B.X.1    Chen, L.B.2    Wang, H.3    Qin, J.4    Shang, L.5
  • 27
    • 84878195751 scopus 로고    scopus 로고
    • The articular cavity washing with safflower injection combined with bearded needle debonding cure knee osteoarthritis
    • (In Chinese)
    • WangZY, RenH and WangHM. The articular cavity washing with safflower injection combined with bearded needle debonding cure knee osteoarthritis. Proceeding of Clinical Medicine21: 494-497, 2012 (In Chinese).
    • (2012) Proceeding of Clinical Medicine , vol.21 , pp. 494-497
    • Wang, Z.Y.1    Ren, H.2    Wang, H.M.3
  • 28
    • 84878174867 scopus 로고    scopus 로고
    • Research progress of amygdalin
    • (In Chinese)
    • LiJS and ZhaoLG: Research progress of amygdalin. Huaxia Medicine2: 326-330, 2007 (In Chinese).
    • (2007) Huaxia Medicine , vol.2 , pp. 326-330
    • Li, J.S.1    Zhao, L.G.2
  • 29
    • 77954052283 scopus 로고    scopus 로고
    • Systems approaches to polypharmacology and drug discovery
    • BoranAD and IyengarR: Systems approaches to polypharmacology and drug discovery. Curr Opin Drug Discov Devel13: 297-309, 2010.
    • (2010) Curr Opin Drug Discov Devel , vol.13 , pp. 297-309
    • Boran, A.D.1    Iyengar, R.2
  • 30
    • 79961129110 scopus 로고    scopus 로고
    • Amygdalin mediates relieved atherosclerosis in apolipoprotein E deficient mice through the induction of regulatory T cells
    • JiagangD, LiC, WangH, HaoE, DuZ, BaoC, LvJ and WangY: Amygdalin mediates relieved atherosclerosis in apolipoprotein E deficient mice through the induction of regulatory T cells. Biochem Biophys Res Commun411: 523-529, 2011.
    • (2011) Biochem Biophys Res Commun , vol.411 , pp. 523-529
    • Jiagang, D.1    Li, C.2    Wang, H.3    Hao, E.4    Du, Z.5    Bao, C.6    Lv, J.7    Wang, Y.8
  • 31
    • 84855994068 scopus 로고    scopus 로고
    • Taoren-Honghua herb pair and its main components promoting blood circulation through influencing on hemorheology, plasma coagulation and platelet aggregation
    • LiuL, DuanJA, TangY, GuoJ, YangN, MaH and ShiX: Taoren-Honghua herb pair and its main components promoting blood circulation through influencing on hemorheology, plasma coagulation and platelet aggregation. JEthnopharmacol139: 381-387, 2012.
    • (2012) JEthnopharmacol , vol.139 , pp. 381-387
    • Liu, L.1    Duan, J.A.2    Tang, Y.3    Guo, J.4    Yang, N.5    Ma, H.6    Shi, X.7
  • 33
    • 84878186844 scopus 로고    scopus 로고
    • Progress in pharmacological research of Taohong Siwu Decoction
    • (In Chinese)
    • LiY and PengDY: Progress in pharmacological research of Taohong Siwu Decoction. Anhui Medical and Pharmaceutical Journal15: 529-531, 2011 (In Chinese).
    • (2011) Anhui Medical and Pharmaceutical Journal , vol.15 , pp. 529-531
    • Li, Y.1    Peng, D.Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.