The multitarget opioid ligand LP1's effects in persistent pain and in primary cell neuronal cultures

Neuropharmacology

Volumn 71, Issue , 2013, Pages 70-82

  Parenti, Carmela ^a   Turnaturi, Rita ^a   Aricò, Giuseppina ^a   Gramowski Voß, Alexandra ^b   Schroeder, Olaf H U ^c   Marrazzo, Agostino ^a   Prezzavento, Orazio ^a   Ronsisvalle, Simone ^a   Scoto, Giovanna M ^a   Ronsisvalle, Giuseppe ^a   Pasquinucci, Lorella ^a  

^a UNIVERSITY OF CATANIA   (Italy)

^b UNIVERSITY OF ROSTOCK   (Germany)

^c NEUROPROOF GMBH   (Germany)

Author keywords

Electrophysiological behaviour; Inflammatory pain; LP1; Micro electrode array (MEA); Neuropathic pain; Opioid receptors

Indexed keywords

3 (8 HYDROXY 6,11 DIMETHYL 1,4,5,6 TETRAHYDRO 2,6 METHANO 3 BENAZOCIN 3(2H) YL) N PHENYLPROPANAMIDE; ANTINOCICEPTIVE AGENT; LP 1; UNCLASSIFIED DRUG;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIHYPERALGESIC EFFECT; ANTINOCICEPTION; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DATA BASE; DRUG EFFECT; DRUG POTENCY; DRUG STRUCTURE; EMBRYO; FRONTAL CORTEX; HYPERALGESIA; IN VITRO STUDY; INFLAMMATION; MALE; MEDIAN EFFECTIVE CONCENTRATION; MOUSE; NERVE CELL NETWORK; NEUROPATHIC PAIN; NEUROPROOF DATABASE; NONHUMAN; PRIORITY JOURNAL; RAT; SCIATIC NERVE; SPINAL CORD;

ANALGESICS, OPIOID; ANIMALS; BENZOMORPHANS; CELLS, CULTURED; CHRONIC PAIN; DISEASE MODELS, ANIMAL; EMBRYO, MAMMALIAN; FRONTAL LOBE; LIGANDS; MALE; MICE; MICE, INBRED STRAINS; NERVE TISSUE PROTEINS; NEURALGIA; NEURONS; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, OPIOID, DELTA; RECEPTORS, OPIOID, MU; SPINAL CORD;

EID: 84878137840     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2013.03.008     Document Type: Article

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