Human amnesia and the medial temporal lobe illuminated by neuropsychological and neurohistological findings for patient E.P.

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 21, 2013, Pages

  Insausti, Ricardo ^a,b,c   Annese, Jacopo ^d   Amaral, David G ^a,b   Squire, Larry R ^d,e,f  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CASTILLA LA MANCHA   (Spain)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; AMNESIA; AMYGDALOID NUCLEUS; ARTICLE; BRAIN CORTEX; CASE REPORT; COGNITION; CONTROLLED STUDY; DECLARATIVE MEMORY; EMOTION; ENTORHINAL CORTEX; FUSIFORM GYRUS; HIPPOCAMPUS; HISTOLOGY; HUMAN; LEARNING; MEDIAL TEMPORAL LOBE; MEMORY DISORDER; MIDDLE TEMPORAL GYRUS; NEUROPSYCHOLOGY; PERIRHINAL CORTEX; PRIORITY JOURNAL; RETROGRADE AMNESIA; ROSTRAL PARAHIPPOCAMPAL CORTEX; SEMANTICS; TEMPORAL LOBE; WHITE MATTER; WORKING MEMORY;

AGED, 80 AND OVER; AMNESIA, RETROGRADE; HUMANS; LEARNING DISORDERS; MALE; TEMPORAL LOBE;

EID: 84878117105     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1306244110     Document Type: Article

References (81)

1. Scoville WB, Milner B (1957) Loss of recent memory after bilateral hippocampal lesions. J Neurol Neurosurg Psychiatry 20(1): 11-21.
2. Victor M, Angevine JB, Jr., Mancall EL, Fisher CM (1961) [Memory loss with lesions of hippocampal formation. Report of a case with some remarks on the anatomical basis of memory]. Arch Neurol 5: 244-263.
3. Bekhterev VW (1900) Demonstration eines Gehirns mit Zerstörung der vorderen und inneren Theile der Hirnrinde beider Schläfenlappen. Neurol Zentralbl 19: 990-991.
4. Mishkin M (1978) Memory in monkeys severely impaired by combined but not by separate removal of amygdala and hippocampus. Nature 273(5660): 297-298.
5. Squire LR, Zola-Morgan S (1991) The medial temporal lobe memory system. Science 253(5026): 1380-1386.
6. Zola-Morgan S, Squire LR, Ramus SJ (1994) Severity of memory impairment in monkeys as a function of locus and extent of damage within the medial temporal lobe memory system. Hippocampus 4(4): 483-495.
7. Squire LR, Stark CEL, Clark RE (2004) The medial temporal lobe. Annu Rev Neurosci 27: 279-306.
8. Zola-Morgan S, Squire LR, Amaral DG (1986) Human amnesia and the medial temporal region: Enduring memory impairment following a bilateral lesion limited to field CA1 of the hippocampus. J Neurosci 6(10): 2950-2967.
9. Victor M, Agamanolis D (1990) Amnesia due to lesions confined to the hippocampus: A clinical-pathologic study. J Cogn Neurosci 2(9): 246-257.
10. Rempel-Clower NL, Zola SM, Squire LR, Amaral DG (1996) Three cases of enduring memory impairment after bilateral damage limited to the hippocampal formation. J Neurosci 16(16): 5233-5255.
11. Gold JJ, Squire LR (2006) The anatomy of amnesia: Neurohistological analysis of three new cases. Learn Mem 13(6): 699-710.
12. Penfield W, Milner B (1958) Memory deficit produced by bilateral lesions in the hippocampal zone. AMA Arch Neurol Psychiatry 79(5): 475-497.
13. PenfieldW, Mathieson G (1974) Memory. Autopsy findings and comments on the role of hippocampus in experiential recall. Arch Neurol 31(3): 145-154.
14. Teuber HL, Milner B, Vaughn HG (1968) Persistent anterograde amnesia after stab wound of the basal brain. Neuropsychologia 6(3): 267-282.
15. Warrington EK, Duchen LW (1992) A re-appraisal of a case of persistent global amnesia following right temporal lobectomy: A clinico-pathological study. Neuropsychologia 30(5): 437-450.
16. Chan D, Revesz T, Rudge P (2002) Hippocampal, but not parahippocampal, damage in a case of dense retrograde amnesia: A pathological study. Neurosci Lett 329(1): 61-64.
17. Stefanacci L, Buffalo EA, Schmolck H, Squire LR (2000) Profound amnesia after damage to the medial temporal lobe: A neuroanatomical and neuropsychological profile of patient E. P. J Neurosci 20(18): 7024-7036.
18. Graham KS, Barense MD, Lee AC (2010) Going beyond LTM in the MTL: A synthesis of neuropsychological and neuroimaging findings on the role of the medial temporal lobe in memory and perception. Neuropsychologia 48(4): 831-853.
19. Barense MD, Rogers TT, Bussey TJ, Saksida LM, Graham KS (2010) Influence of conceptual knowledge on visual object discrimination: Insights from semantic dementia and MTL amnesia. Cereb Cortex 20(11): 2568-2582.
20. Reed JM, Squire LR (1998) Retrograde amnesia for facts and events: Findings from four new cases. J Neurosci 18(10): 3943-3954.
21. Mattis S (1976) Dementia Rating Scale. Geriatric Psychiatry X, eds Bellack R, Keraso B (Grune and Stratton, New York), pp 77-121.
22. Janowsky JS, Shimamura AP, Kritchevsky M, Squire LR (1989) Cognitive impairment following frontal lobe damage and its relevance to human amnesia. Behav Neurosci 103(3): 548-560.
23. Anderson SW, Damasio H, Jones RD, Tranel D (1991) Wisconsin Card Sorting Test performance as a measure of frontal lobe damage. J Clin Exp Neuropsychol 13(6): 909-922.
24. Milner B (1963) Effects of different brain lesions on card sorting. Arch Neurol 9(1): 90-100.
25. Stark CEL, Squire LR (2000) Recognition memory and familiarity judgments in severe amnesia: No evidence for a contribution of repetition priming. Behav Neurosci 114(3): 459-467.
26. Levy DA, Shrager Y, Squire LR (2005) Intact visual discrimination of complex and feature-ambiguous stimuli in the absence of perirhinal cortex. Learn Mem 12(1): 61-66.
27. Shrager Y, Gold JJ, Hopkins RO, Squire LR (2006) Intact visual perception in memoryimpaired patients with medial temporal lobe lesions. J Neurosci 26(8): 2235-2240.
28. Schacter DL, Cooper LA, Delaney SM (1990) Implicit memory for unfamiliar objects depends on access to structural descriptions. J Exp Psychol Gen 119(1): 5-24.
29. Williams P, Tarr MJ (1997) Structural processing and implicit memory for possible and impossible figures. J Exp Psychol Learn Mem Cogn 23(6): 1344-1361.
30. Kaplan EF, Goodglass H, Weintraub S (1983) The Boston Naming Test (Lea Febiger, Philadelphia).
31. Kensinger EA, Ullman MT, Corkin S (2001) Bilateral medial temporal lobe damage does not affect lexical or grammatical processing: Evidence from amnesic patient H.M. Hippocampus 11(4): 347-360.
32. Schmolck H, Stefanacci L, Squire LR (2000) Detection and explanation of sentence ambiguity are unaffected by hippocampal lesions but are impaired by larger temporal lobe lesions. Hippocampus 10(6): 759-770.
33. Schmolck H, Kensinger EA, Corkin S, Squire LR (2002) Semantic knowledge in patient H.M. and other patients with bilateral medial and lateral temporal lobe lesions. Hippocampus 12(4): 520-533.
34. Hodges JR, Patterson K, Oxbury S, Funnell E (1992) Semantic dementia. Progressive fluent aphasia with temporal lobe atrophy. Brain 115(Pt 6): 1783-1806.
35. Hamann SB, Cahill L, Squire LR (1997) Emotional perception and memory in amnesia. Neuropsychology 11(1): 104-113.
36. Schmolck H, Squire LR (2001) Impaired perception of facial emotions following bilateral damage to the anterior temporal lobe. Neuropsychology 15(1): 30-38.
37. Cave CB, Squire LR (1992) Intact verbal and nonverbal short-term memory following damage to the human hippocampus. Hippocampus 2(2): 151-163.
38. Keane MM, Gabrieli JD, Mapstone HC, Johnson KA, Corkin S (1995) Double dissociation of memory capacities after bilateral occipital-lobe or medial temporallobe lesions. Brain 118(Pt 5): 1129-1148.
39. Shrager Y, Levy DA, Hopkins RO, Squire LR (2008) Working memory and the organization of brain systems. J Neurosci 28(18): 4818-4822.
40. Shrager Y, Kirwan CB, Squire LR (2008) Neural basis of the cognitive map: Path integration does not require hippocampus or entorhinal cortex. Proc Natl Acad Sci USA 105(33): 12034-12038.
41. Teng E, Squire LR (1999) Memory for places learned long ago is intact after hippocampal damage. Nature 400(6745): 675-677.
42. Hamann SB, Squire LR (1997) Intact perceptual memory in the absence of conscious memory. Behav Neurosci 111(4): 850-854.
43. Clark RE, Squire LR (1998) Classical conditioning and brain systems: The role of awareness. Science 280(5360): 77-81.
44. Freed DM, Corkin S, Cohen NJ (1987) Forgetting in H.M.: A second look. Neuropsychologia 25(3): 461-471.
45. Reed JM, Hamann SB, Stefanacci L, Squire LR (1997) When amnesic patients perform well on recognition memory tests. Behav Neurosci 111(6): 1163-1170.
46. Bayley PJ, O'Reilly RC, Curran T, Squire LR (2008) New semantic learning in patients with large medial temporal lobe lesions. Hippocampus 18(6): 575-583.
47. Bayley PJ, Hopkins RO, Squire LR (2006) The fate of old memories after medial temporal lobe damage. J Neurosci 26(51): 13311-13317.
48. Kopelman MD, Wilson BA, Baddeley AD (1989) The autobiographical memory interview: A new assessment of autobiographical and personal semantic memory in amnesic patients. J Clin Exp Neuropsychol 11(5): 724-744.
49. Bayley PJ, Hopkins RO, Squire LR (2003) Successful recollection of remote autobiographical memories by amnesic patients with medial temporal lobe lesions. Neuron 37: 135-144.
50. Bayley PJ, Gold JJ, Hopkins RO, Squire LR (2005) The neuroanatomy of remote memory. Neuron 46(5): 799-810.
51. Kirwan CB, Bayley PJ, Galván VV, Squire LR (2008) Detailed recollection of remote autobiographical memory after damage to the medial temporal lobe. Proc Natl Acad Sci USA 105(7): 2676-2680.
52. Conroy MA, Hopkins RO, Squire LR (2005) On the contribution of perceptual fluency and priming to recognition memory. Cogn Affect Behav Neurosci 5(1): 14-20.
53. Levy DA, Stark CEL, Squire LR (2004) Intact conceptual priming in the absence of declarative memory. Psychol Sci 15(10): 680-686.
54. Squire LR, Knowlton BJ (1995) Learning about categories in the absence of memory. Proc Natl Acad Sci USA 92(26): 12470-12474.
55. Reed JM, Squire LR, Patalano AL, Smith EE, Jonides J (1999) Learning about categories that are defined by object-like stimuli despite impaired declarative memory. Behav Neurosci 113(3): 411-419.
56. Reber PJ, Squire LR (1998) Encapsulation of implicit and explicit memory in sequence learning. J Cogn Neurosci 10(2): 248-263.
57. Berry CJ, Shanks DR, Speekenbrink M, Henson RN (2012) Models of recognition, repetition priming, and fluency: Exploring a new framework. Psychol Rev 119(1): 40-79.
58. Bayley PJ, Squire LR (2002) Medial temporal lobe amnesia: Gradual acquisition of factual information by nondeclarative memory. J Neurosci 22(13): 5741-5748.
59. Bayley PJ, Frascino JC, Squire LR (2005) Robust habit learning in the absence of awareness and independent of the medial temporal lobe. Nature 436(7050): 550-553.
60. Blaizot X, et al. (2010) The human parahippocampal region: I. Temporal pole cytoarchitectonic and MRI correlation. Cereb Cortex 20(9): 2198-2212.
61. Brodmann K (1909) Vergleichende Lokalisationslehre der Grosshirnrinde in ihren Prinzipien dargestellt auf Grund des Zellenbaues [Comparative Localization Studies in the Brain Cortex, its Fundamentals Represented on the Basis of its Cellular Architecture] (Barth, Leipzig) in German.
62. Bailey P, von BoninG (1951) The Isocortex ofMan (University of Illinois Press, Urbana, IL).
63. Corkin S, Amaral DG, González RG, Johnson KA, Hyman BT (1997) H. M.'s medial temporal lobe lesion: Findings from magnetic resonance imaging. J Neurosci 17(10): 3964-3979.
64. O'Kane G, Kensinger EA, Corkin S (2004) Evidence for semantic learning in profound amnesia: An investigation with patient H.M. Hippocampus 14(4): 417-425.
65. Bayley PJ, Squire LR (2005) Failure to acquire new semantic knowledge in patients with large medial temporal lobe lesions. Hippocampus 15(2): 273-280.
66. Horel JA (1978) The neuroanatomy of amnesia. A critique of the hippocampal memory hypothesis. Brain 101(3): 403-445.
67. Gaffan D (2002) Against memory systems. Philos Trans R Soc Lond B Biol Sci 357(1424): 1111-1121.
68. Zola-Morgan S, Squire LR, Mishkin M (1982) The neuroanatomy of amnesia: Amygdala-hippocampus versus temporal stem. Science 218(4579): 1337-1339.
69. Zola-Morgan S, Squire LR (1984) Preserved learning in monkeys with medial temporal lesions: Sparing of motor and cognitive skills. J Neurosci 4(4): 1072-1085.
70. Adolphs R (2008) Fear, faces, and the human amygdala. Curr Opin Neurobiol 18(2): 166-172.
71. Kanwisher N, Yovel G (2006) The fusiform face area: A cortical region specialized for the perception of faces. Philos Trans Roy Soc Lond Series B 361(1476): 2109-2128.
72. Hodges JR, Graham KS (2001) Episodic memory: Insights from semantic dementia. Philos Trans Roy Soc Lond Series B 356(17): 1423-1434.
73. Levy DA, Bayley PJ, Squire LR (2004) The anatomy of semantic knowledge: Medial vs. lateral temporal lobe. Proc Natl Acad Sci USA 101(17): 6710-6715.
74. Mummery CJ, et al. (2000) A voxel-based morphometry study of semantic dementia: Relationship between temporal lobe atrophy and semantic memory. Ann Neurol 47(1): 36-45.
75. Galton CJ, et al. (2001) Differing patterns of temporal atrophy in Alzheimer's disease and semantic dementia. Neurology 57(2): 216-225.
76. Hodges JR, et al. (1999) The differentiation of semantic dementia and frontal lobe dementia (temporal and frontal variants of frontotemporal dementia) from early Alzheimer's disease: A comparative neuropsychological study. Neuropsychology 13(1): 31-40.
77. Davies RR, Xuereb JH, Hodges JR (2002) The human perirhinal cortex in semantic memory: An in vivo and postmortem volumetric magnetic resonance imaging study in semantic dementia, Alzheimer's disease and matched controls. Neuropathol Appl Neurobiol 28(5): 167-168.
78. Suzuki WA (2009) Perception and the medial temporal lobe: Evaluating the current evidence. Neuron 61(5): 657-666.
79. Squire LR, Wixted JT (2011) The cognitive neuroscience of human memory since H.M. Annu Rev Neurosci 34: 259-288.
80. Van Essen DC, Maunsell JHR (1980) Two-dimensional maps of the cerebral cortex. J Comp Neurol 191(2): 255-281.
81. Insausti R, et al. (1998) MRI-based volumetric analyses of the human entorhinal, perirhinal and temporopolar cortices. AJNR Am J Neuroradiol 16: 659-671.