Progression of experimental lesions of atherosclerosis: Assessment by kinetic modeling of black-blood dynamic contrast-enhanced MRI

Magnetic Resonance in Medicine

Volumn 69, Issue 6, 2013, Pages 1712-1720

  Chen, Huijun ^a   Ricks, Jerry ^b   Rosenfeld, Michael ^b   Kerwin, William S ^a,c  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c VPDiagnostics Inc   (United States)

Author keywords

atherosclerosis; dynamic contrast enhanced MRI; inflammation

Indexed keywords

BLOOD; DISEASES; KINETIC PARAMETERS; KINETIC THEORY; PATHOLOGY; PHARMACOKINETICS; PHYSIOLOGICAL MODELS;

ATHEROSCLEROSIS; ATHEROSCLEROTIC LESIONS; DYNAMIC CONTRAST ENHANCED MRI; HISTOLOGICAL ANALYSIS; INFLAMMATION; NEW ZEALAND WHITE RABBIT; PATHOLOGICAL CHANGES; PHARMACOKINETIC MODEL;

MAGNETIC RESONANCE IMAGING;

GADOBENATE DIMEGLUMINE;

ABDOMINAL AORTA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROSIS; BLOOD; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DYNAMIC CONTRAST ENHANCED MAGNETIC RESONANCE IMAGING; EXPERIMENTAL RABBIT; HISTOLOGY; KINETICS; MACROPHAGE; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; SIGNAL DETECTION;

EID: 84878114548     PISSN: 07403194     EISSN: 15222594     Source Type: Journal    
DOI: 10.1002/mrm.24415     Document Type: Article

References (28)

1. Corti R, Fuster V, Fayad ZA, et al. Lipid lowering by simvastatin induces regression of human atherosclerotic lesions: two years' follow-up by high-resolution noninvasive magnetic resonance imaging. Circulation 2002; 106: 2884-2887.
2. Fayad ZA, Mani V, Woodward M, et al. Safety and efficacy of dalcetrapib on atherosclerotic disease using novel non-invasive multimodality imaging (dal-plaque): a randomised clinical trial. Lancet 2011; 378: 1547-1559.
3. Underhill HR, Yuan C, Zhao XQ, et al. Effect of rosuvastatin therapy on carotid plaque morphology and composition in moderately hypercholesterolemic patients: a high-resolution magnetic resonance imaging trial. Am Heart J 2008; 155: 584.e1-584.e8.
4. Zhao XQ, Dong L, Hatsukami T, et al. MR imaging of carotid plaque composition during lipid-lowering therapy a prospective assessment of effect and time course. JACC Cardiovasc Imaging 2011; 4: 977-986.
5. Vucic E, Dickson SD, Calcagno C, et al. Pioglitazone modulates vascular inflammation in atherosclerotic rabbits noninvasive assessment with FDG-PET-CT and dynamic contrast-enhanced MR imaging. JACC Cardiovasc Imaging 2011; 4: 1100-1109.
6. Dong L, Kerwin WS, Chen H, Chu B, Underhill HR, Neradilek MB, Hatsukami TS, Yuan C, Zhao XQ,. Carotid artery atherosclerosis: effect of intensive lipid therapy on the vasa vasorum-evaluation by using dynamic contrast-enhanced MR imaging. Radiology 2011; 260: 224-231.
7. Kerwin W, Hooker A, Spilker M, Vicini P, Ferguson M, Hatsukami T, Yuan C,. Quantitative MRI analysis of neovasculature volume in carotid atherosclerotic plaque. Circulation 2003; 107: 851-856.
8. Kerwin WS, O'Brien KD, Ferguson MS, Polissar N, Hatsukami TS, Yuan C,. Inflammation in carotid atherosclerotic plaque is associated with elevated neovasculature and permeability: a dynamic contrast-enhanced MRI study. Radiology 2006; 241: 459-468.
9. Kerwin WS, Oikawa M, Yuan C, Jarvik GP, Hatsukami TS,. MR imaging of adventitial vasa vasorum in carotid atherosclerosis. Magn Reson Med 2008; 59: 507-514.
10. Libby P,. Inflammation in atherosclerosis. Nature 2002; 420: 868-874.
11. Arthurs ZM, Andersen C, Starnes BW, Sohn VY, Mullenix PS, Perry J,. A prospective evaluation of C-reactive protein in the progression of carotid artery stenosis. J Vasc Surg 2008; 47: 744-750.
12. Mofidi R, Crotty TB, McCarthy P, Sheehan SJ, Mehigan D, Keaveny TV,. Association between plaque instability, angiogenesis and symptomatic carotid occlusive disease. Br J Surg 2001; 88: 945-950.
13. McCarthy MJ, Loftus IM, Thompson MM, Jones L, London NJ, Bell PR, Naylor AR, Brindle NP,. Angiogenesis and the atherosclerotic carotid plaque: an association between symptomatology and plaque morphology. J Vasc Surg 1999; 30: 261-268.
14. Dunmore BJ, McCarthy MJ, Naylor AR, Brindle NP,. Carotid plaque instability and ischemic symptoms are linked to immaturity of microvessels within plaques. J Vasc Surg 2007; 45: 155-159.
15. Virmani R, Kolodgie FD, Burke AP, Finn AV, Gold HK, Tulenko TN, Wrenn SP, Narula J,. Atherosclerotic plaque progression and vulnerability to rupture: angiogenesis as a source of intraplaque hemorrhage. Arterioscler Thromb Vasc Biol 2005; 25: 2054-2061.
16. Calcagno C, Cornily JC, Hyafil F, Rudd JH, Briley-Saebo KC, Mani V, Goldschlager G, Machac J, Fuster V, Fayad ZA,. Detection of neovessels in atherosclerotic plaques of rabbits using dynamic contrast enhanced MRI and 18F-FDG PET. Arterioscler Thromb Vasc Biol 2008; 28: 1311-1317.
17. Calcagno C, Vucic E, Mani V, Goldschlager G, Fayad ZA,. Reproducibility of black blood dynamic contrast-enhanced magnetic resonance imaging in aortic plaques of atherosclerotic rabbits. J Magn Reson Imaging 2010; 32: 191-198.
18. 1-insensitive flow suppression using quadruple inversion-recovery. Magn Reson Med 2002; 48: 899-905.
19. Yarnykh VL, Yuan C,. Simultaneous outer volume and blood suppression by quadruple inversion-recovery. Magn Reson Med 2006; 55: 1083-1092.
20. Kerwin W, Xu D, Liu F, Saam T, Underhill H, Takaya N, Chu B, Hatsukami T, Yuan C,. Magnetic resonance imaging of carotid atherosclerosis: plaque analysis. Top Magn Reson Imaging 2007; 18: 371-378.
21. Wu YG,. Noninvasive quantification of local cerebral metabolic rate of glucose for clinical application using positron emission tomography and 18F-fluoro-2-deoxy- D -glucose. J Cereb Blood Flow Metab 2008; 28: 242-250.
22. Jaspers K, Leiner T, Dijkstra P, Oostendorp M, van Golde JM, Post MJ, Backes WH,. Optimized pharmacokinetic modeling for the detection of perfusion differences in skeletal muscle with DCE-MRI: effect of contrast agent size. Med Phys 2010; 37: 5746-5755.
23. Saam T, Kerwin WS, Chu B, et al. Sample size calculation for clinical trials using magnetic resonance imaging for the quantitative assessment of carotid atherosclerosis. J Cardiovasc Magn Reson 2005; 7: 799-808.
24. Stary HC, Chandler AB, Dinsmore RE, Fuster V, Glagov S, Insull W Jr, Rosenfeld ME, Schwartz CJ, Wagner WD, Wissler RW,. A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association. Circulation 1995; 92: 1355-1374.
25. Moreno PR, Purushothaman KR, Sirol M, Levy AP, Fuster V,. Neovascularization in human atherosclerosis. Circulation 2006; 113: 2245-2252.
26. Ramos MA, Kuzuya M, Esaki T, Miura S, Satake S, Asai T, Kanda S, Hayashi T, Iguchi A,. Induction of macrophage VEGF in response to oxidized LDL and VEGF accumulation in human atherosclerotic lesions. Arterioscler Thromb Vasc Biol 1998; 18: 1188-1196.
27. Kolodgie FD, Gold HK, Burke AP, et al. Intraplaque hemorrhage and progression of coronary atheroma. N Engl J Med 2003; 349: 2316-2325.
28. Chen H, Li F, Zhao X, Yuan C, Rutt B, Kerwin WS,. Extended graphical model for analysis of dynamic contrast-enhanced MRI. Magn Reson Med 2011; 66: 868-878.