Synthesis of novel strobilurin-pyrimidine derivatives and their antiproliferative activity against human cancer cell lines

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 12, 2013, Pages 3505-3510

  Chai, Baoshan ^a,b   Wang, Shuyang ^a   Yu, Wenquan ^a   Li, Huichao ^b   Song, Chuanjun ^a   Xu, Ying ^b   Liu, Changling ^b   Chang, Junbiao ^a  

^a ZHENGZHOU UNIVERSITY   (China)

^b Shenyang Research Institute of Chemical Industry Co Ltd   (China)

Author keywords

Antiproliferative activity; Leukemia; Lung cancer; Strobilurin pyrimidine; Structure activity relationship

Indexed keywords

ANTINEOPLASTIC AGENT; DOXORUBICIN; FLUACRYPYRIM; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; LEUKEMIA; STRUCTURE ACTIVITY RELATION;

CELL LINE, TUMOR; CELL PROLIFERATION; DRUG SCREENING ASSAYS, ANTITUMOR; FATTY ACIDS, UNSATURATED; HL-60 CELLS; HUMANS; LEUKEMIA; LUNG NEOPLASMS; METHACRYLATES; PYRIMIDINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84878113550     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2013.04.045     Document Type: Article

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