-
1
-
-
77951589703
-
Clinical assessment incorporating a personal genome
-
Ashley, E.A. et al. Clinical assessment incorporating a personal genome. Lancet 375, 1525-1535 (2010).
-
(2010)
Lancet
, vol.375
, pp. 1525-1535
-
-
Ashley, E.A.1
-
2
-
-
77950507176
-
Individual genomes on the horizon
-
Lifton, R.P. Individual genomes on the horizon. N. Engl. J. Med. 362, 1235-1236 (2010).
-
(2010)
N. Engl. J. Med.
, vol.362
, pp. 1235-1236
-
-
Lifton, R.P.1
-
3
-
-
46449113799
-
Electronic health records in ambulatory care - A national survey of physicians
-
DesRoches, C.M. et al. Electronic health records in ambulatory care - a national survey of physicians. N. Engl. J. Med. 359, 50-60 (2008).
-
(2008)
N. Engl. J. Med.
, vol.359
, pp. 50-60
-
-
DesRoches, C.M.1
-
4
-
-
64749093541
-
Use of electronic health records in U.S. hospitals
-
Jha, A.K. et al. Use of electronic health records in U.S. hospitals. N. Engl. J. Med. 360, 1628-1638 (2009).
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 1628-1638
-
-
Jha, A.K.1
-
5
-
-
74849087466
-
Accelerating the use of electronic health records in physician practices
-
Shea, S. & Hripcsak, G. Accelerating the use of electronic health records in physician practices. N. Engl. J. Med. 362, 192-195 (2010).
-
(2010)
N. Engl. J. Med.
, vol.362
, pp. 192-195
-
-
Shea, S.1
Hripcsak, G.2
-
6
-
-
47249112582
-
Quality performance measurement using the text of electronic medical records
-
Pakhomov, S., Bjornsen, S., Hanson, P. & Smith, S. Quality performance measurement using the text of electronic medical records. Med. Decis. Making 28, 462-470 (2008).
-
(2008)
Med. Decis. Making
, vol.28
, pp. 462-470
-
-
Pakhomov, S.1
Bjornsen, S.2
Hanson, P.3
Smith, S.4
-
7
-
-
62749158308
-
Identifying QT prolongation from ECG impressions using a general-purpose Natural Language Processor
-
Denny, J.C., Miller, R.A., Waitman, L.R., Arrieta, M.A. & Peterson, J.F. Identifying QT prolongation from ECG impressions using a general-purpose Natural Language Processor. Int. J. Med. Inform. 78 (suppl. 1), S34-S42 (2009).
-
(2009)
Int. J. Med. Inform.
, vol.78
, Issue.SUPPL. 1
-
-
Denny, J.C.1
Miller, R.A.2
Waitman, L.R.3
Arrieta, M.A.4
Peterson, J.F.5
-
8
-
-
84889363837
-
The HMO Research Network
-
4th edn., (ed. Strom, B.L.) Wiley & Sons, West Sussex, UK
-
Chan, K.A. et al. The HMO Research Network. In Pharmacoepidemiology 4th edn., (ed. Strom, B.L.) 261-270 (Wiley & Sons, West Sussex, UK, 2007).
-
(2007)
Pharmacoepidemiology
, pp. 261-270
-
-
Chan, K.A.1
-
9
-
-
77950477064
-
MedEx: A medication information extraction system for clinical narratives
-
Xu, H., Stenner, S.P., Doan, S., Johnson, K.B., Waitman, L.R. & Denny, J.C. MedEx: a medication information extraction system for clinical narratives. J. Am. Med. Inform. Assoc. 17, 19-24 (2010).
-
(2010)
J. Am. Med. Inform. Assoc.
, vol.17
, pp. 19-24
-
-
Xu, H.1
Stenner, S.P.2
Doan, S.3
Johnson, K.B.4
Waitman, L.R.5
Denny, J.C.6
-
10
-
-
77951541774
-
Biobanking and pharmacogenomics
-
McCarty, C.A. & Wilke, R.A. Biobanking and pharmacogenomics. Pharmacogenomics 11, 637-641 (2010).
-
(2010)
Pharmacogenomics
, vol.11
, pp. 637-641
-
-
McCarty, C.A.1
Wilke, R.A.2
-
11
-
-
77951533290
-
Genome-wide association of lipid-lowering response to statins in combined study populations
-
Barber, M.J. et al. Genome-wide association of lipid-lowering response to statins in combined study populations. PLoS ONE 5, e9763 (2010).
-
(2010)
PLoS ONE
, vol.5
-
-
Barber, M.J.1
-
12
-
-
27644529477
-
Marshfield Clinic Personalized Medicine Research Project (PMRP): Design, methods and recruitment for a large population-based biobank
-
McCarty, C.A. et al. Marshfield Clinic Personalized Medicine Research Project (PMRP): design, methods and recruitment for a large population-based biobank. Personalized Med 2, 49-79 (2005).
-
(2005)
Personalized Med
, vol.2
, pp. 49-79
-
-
McCarty, C.A.1
-
13
-
-
49949093313
-
Development of a large-scale de-identified DNA biobank to enable personalized medicine
-
Roden, D.M. et al. Development of a large-scale de-identified DNA biobank to enable personalized medicine. Clin. Pharmacol. Ther. 84, 362-369 (2008).
-
(2008)
Clin. Pharmacol. Ther.
, vol.84
, pp. 362-369
-
-
Roden, D.M.1
-
14
-
-
59849085993
-
Assessing the understanding of biobank participants
-
Ormond, K.E., Cirino, A.L., Helenowski, I.B., Chisholm, R.L. & Wolf, W.A. Assessing the understanding of biobank participants. Am. J. Med. Genet. A 149A, 188-198 (2009).
-
(2009)
Am. J. Med. Genet. A
, vol.149 A
, pp. 188-198
-
-
Ormond, K.E.1
Cirino, A.L.2
Helenowski, I.B.3
Chisholm, R.L.4
Wolf, W.A.5
-
15
-
-
77950338000
-
Robust replication of genotype-phenotype associations across multiple diseases in an electronic medical record
-
Ritchie, M.D. et al. Robust replication of genotype-phenotype associations across multiple diseases in an electronic medical record. Am. J. Hum. Genet. 86, 560-572 (2010).
-
(2010)
Am. J. Hum. Genet.
, vol.86
, pp. 560-572
-
-
Ritchie, M.D.1
-
16
-
-
0017181612
-
Protocol-based computer reminders, the quality of care and the non-perfectability of man
-
McDonald, C.J. Protocol-based computer reminders, the quality of care and the non-perfectability of man. N. Engl. J. Med. 295, 1351-1355 (1976).
-
(1976)
N. Engl. J. Med.
, vol.295
, pp. 1351-1355
-
-
McDonald, C.J.1
-
17
-
-
0017598020
-
A computer-based record and clinical monitoring system for ambulatory care
-
McDonald, C.J., Murray, R., Jeris, D., Bhargava, B., Seeger, J. & Blevins, L. A computer-based record and clinical monitoring system for ambulatory care. Am. J. Public Health 67, 240-245 (1977).
-
(1977)
Am. J. Public Health
, vol.67
, pp. 240-245
-
-
McDonald, C.J.1
Murray, R.2
Jeris, D.3
Bhargava, B.4
Seeger, J.5
Blevins, L.6
-
18
-
-
50649122567
-
Extracting information from textual documents in the electronic health record: A review of recent research
-
Meystre, S.M., Savova, G.K., Kipper-Schuler, K.C. & Hurdle, J.F. Extracting information from textual documents in the electronic health record: a review of recent research. Yearb. Med. Inform. 128-144 (2008).
-
(2008)
Yearb. Med. Inform.
, pp. 128-144
-
-
Meystre, S.M.1
Savova, G.K.2
Kipper-Schuler, K.C.3
Hurdle, J.F.4
-
19
-
-
0032545976
-
Conventional compared with individualized chemotherapy for childhood acute lymphoblastic leukemia
-
Evans, W.E., Relling, M.V., Rodman, J.H., Crom, W.R., Boyett, J.M. & Pui, C.H. Conventional compared with individualized chemotherapy for childhood acute lymphoblastic leukemia. N. Engl. J. Med. 338, 499-505 (1998).
-
(1998)
N. Engl. J. Med.
, vol.338
, pp. 499-505
-
-
Evans, W.E.1
Relling, M.V.2
Rodman, J.H.3
Crom, W.R.4
Boyett, J.M.5
Pui, C.H.6
-
20
-
-
20644448824
-
Relative impact of CYP3A genotype and concomitant medication on the severity of atorvastatin-induced muscle damage
-
Wilke, R.A., Moore, J.H. & Burmester, J.K. Relative impact of CYP3A genotype and concomitant medication on the severity of atorvastatin-induced muscle damage. Pharmacogenet. Genomics 15, 415-421 (2005).
-
(2005)
Pharmacogenet. Genomics
, vol.15
, pp. 415-421
-
-
Wilke, R.A.1
Moore, J.H.2
Burmester, J.K.3
-
21
-
-
0033569516
-
Pharmacogenomics: Translating functional genomics into rational therapeutics
-
Evans, W.E. & Relling, M.V. Pharmacogenomics: translating functional genomics into rational therapeutics. Science 286, 487-491 (1999).
-
(1999)
Science
, vol.286
, pp. 487-491
-
-
Evans, W.E.1
Relling, M.V.2
-
22
-
-
35748961114
-
Identifying genetic risk factors for serious adverse drug reactions: Current progress and challenges
-
Wilke, R.A. et al. Identifying genetic risk factors for serious adverse drug reactions: current progress and challenges. Nat. Rev. Drug Discov. 6, 904-916 (2007).
-
(2007)
Nat. Rev. Drug Discov.
, vol.6
, pp. 904-916
-
-
Wilke, R.A.1
-
23
-
-
60849097257
-
Estimation of the warfarin dose with clinical and pharmacogenetic data
-
International Warfarin Pharmacogenetics Consortium
-
Klein, T.E. et al.; International Warfarin Pharmacogenetics Consortium. Estimation of the warfarin dose with clinical and pharmacogenetic data. N. Engl. J. Med. 360, 753-764 (2009).
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 753-764
-
-
Klein, T.E.1
-
24
-
-
0034567167
-
A broad-coverage natural language processing system
-
Friedman, C. A broad-coverage natural language processing system. Proc. AMIA Symp. 270-274 (2000).
-
(2000)
Proc. AMIA Symp.
, pp. 270-274
-
-
Friedman, C.1
-
25
-
-
56149096884
-
Use of natural language programming to extract medication from unstructured electronic medical records
-
Chhieng, D., Day, T., Gordon, G. & Hicks, J. Use of natural language programming to extract medication from unstructured electronic medical records. AMIA Annu. Symp. Proc. 908 (2007).
-
(2007)
AMIA Annu. Symp. Proc.
, pp. 908
-
-
Chhieng, D.1
Day, T.2
Gordon, G.3
Hicks, J.4
-
26
-
-
60949110325
-
Assessment of commercial NLP engines for medication information extraction from dictated clinical notes
-
Jagannathan, V. et al. Assessment of commercial NLP engines for medication information extraction from dictated clinical notes. Int. J. Med. Inform. 78, 284-291 (2009).
-
(2009)
Int. J. Med. Inform.
, vol.78
, pp. 284-291
-
-
Jagannathan, V.1
-
27
-
-
52049123312
-
Characterization of low-density lipoprotein cholesterol-lowering efficacy for atorvastatin in a population-based DNA biorepository
-
Wilke, R.A., Berg, R.L., Linneman, J.G., Zhao, C., McCarty, C.A. & Krauss, R.M. Characterization of low-density lipoprotein cholesterol-lowering efficacy for atorvastatin in a population-based DNA biorepository. Basic Clin. Pharmacol. Toxicol. 103, 354-359 (2008).
-
(2008)
Basic Clin. Pharmacol. Toxicol.
, vol.103
, pp. 354-359
-
-
Wilke, R.A.1
Berg, R.L.2
Linneman, J.G.3
Zhao, C.4
McCarty, C.A.5
Krauss, R.M.6
-
28
-
-
57049133083
-
Benefits and risks of drug treatments: How to combine the best evidence on benefits with the best data about adverse effects
-
Vandenbroucke, J.P. & Psaty, B.M. Benefits and risks of drug treatments: how to combine the best evidence on benefits with the best data about adverse effects. JAMA 300, 2417-2419 (2008).
-
(2008)
JAMA
, vol.300
, pp. 2417-2419
-
-
Vandenbroucke, J.P.1
Psaty, B.M.2
-
29
-
-
34347209807
-
Statin and statin-fibrate use was significantly associated with increased myositis risk in a managed care population
-
McClure, D.L., Valuck, R.J., Glanz, M., Murphy, J.R. & Hokanson, J.E. Statin and statin-fibrate use was significantly associated with increased myositis risk in a managed care population. J. Clin. Epidemiol. 60, 812-818 (2007).
-
(2007)
J. Clin. Epidemiol.
, vol.60
, pp. 812-818
-
-
McClure, D.L.1
Valuck, R.J.2
Glanz, M.3
Murphy, J.R.4
Hokanson, J.E.5
-
30
-
-
64249111190
-
Use of an electronic medical record to characterize cases of intermediate statin-induced muscle toxicity
-
Mareedu, R.K. et al. Use of an electronic medical record to characterize cases of intermediate statin-induced muscle toxicity. Prev. Cardiol. 12, 88-94 (2009).
-
(2009)
Prev. Cardiol.
, vol.12
, pp. 88-94
-
-
Mareedu, R.K.1
-
31
-
-
27844492326
-
Combinatorial pharmacogenetics
-
Wilke, R.A., Reif, D.M. & Moore, J.H. Combinatorial pharmacogenetics. Nat. Rev. Drug Discov. 4, 911-918 (2005).
-
(2005)
Nat. Rev. Drug Discov.
, vol.4
, pp. 911-918
-
-
Wilke, R.A.1
Reif, D.M.2
Moore, J.H.3
-
32
-
-
0036843479
-
Effects of fibrates on metabolism of statins in human hepatocytes
-
Prueksaritanont, T., Tang, C., Qiu, Y., Mu, L., Subramanian, R. & Lin, J.H. Effects of fibrates on metabolism of statins in human hepatocytes. Drug Metab. Dispos. 30, 1280-1287 (2002).
-
(2002)
Drug Metab. Dispos.
, vol.30
, pp. 1280-1287
-
-
Prueksaritanont, T.1
Tang, C.2
Qiu, Y.3
Mu, L.4
Subramanian, R.5
Lin, J.H.6
-
33
-
-
72849145686
-
UDP-glucuronosyltransferase (UGT) polymorphisms affect atorvastatin lactonization in vitro and in vivo
-
Riedmaier, S. et al. UDP-glucuronosyltransferase (UGT) polymorphisms affect atorvastatin lactonization in vitro and in vivo. Clin. Pharmacol. Ther. 87, 65-73 (2010).
-
(2010)
Clin. Pharmacol. Ther.
, vol.87
, pp. 65-73
-
-
Riedmaier, S.1
-
34
-
-
49949104757
-
SLCO1B1 variants and statin-induced myopathy-a genomewide study
-
SEARCH Collaborative Group
-
Link, E. et al.; SEARCH Collaborative Group. SLCO1B1 variants and statin-induced myopathy-a genomewide study. N. Engl. J. Med. 359, 789-799 (2008).
-
(2008)
N. Engl. J. Med.
, vol.359
, pp. 789-799
-
-
Link, E.1
-
35
-
-
67651172794
-
ABCG2 polymorphism markedly affects the pharmacokinetics of atorvastatin and rosuvastatin
-
Keskitalo, J.E., Zolk, O., Fromm, M.F., Kurkinen, K.J., Neuvonen, P.J. & Niemi, M. ABCG2 polymorphism markedly affects the pharmacokinetics of atorvastatin and rosuvastatin. Clin. Pharmacol. Ther. 86, 197-203 (2009).
-
(2009)
Clin. Pharmacol. Ther.
, vol.86
, pp. 197-203
-
-
Keskitalo, J.E.1
Zolk, O.2
Fromm, M.F.3
Kurkinen, K.J.4
Neuvonen, P.J.5
Niemi, M.6
-
36
-
-
67349174180
-
Estrogen receptor genotype is associated with risk of venous thromboembolism during tamoxifen therapy
-
Onitilo, A.A. et al. Estrogen receptor genotype is associated with risk of venous thromboembolism during tamoxifen therapy. Breast Cancer Res. Treat. 115, 643-650 (2009).
-
(2009)
Breast Cancer Res. Treat.
, vol.115
, pp. 643-650
-
-
Onitilo, A.A.1
-
37
-
-
77950893913
-
Breast cancer recurrence risk related to concurrent use of SSRI antidepressants and tamoxifen
-
Lash, T.L. et al. Breast cancer recurrence risk related to concurrent use of SSRI antidepressants and tamoxifen. Acta Oncol. 49, 305-312 (2010).
-
(2010)
Acta Oncol.
, vol.49
, pp. 305-312
-
-
Lash, T.L.1
-
38
-
-
77952521444
-
Effect of concomitant CYP2D6 inhibitor use and tamoxifen adherence on breast cancer recurrence in early-stage breast cancer
-
Dezentjé, V.O. et al. Effect of concomitant CYP2D6 inhibitor use and tamoxifen adherence on breast cancer recurrence in early-stage breast cancer. J. Clin. Oncol. 28, 2423-2429 (2010).
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 2423-2429
-
-
Dezentjé, V.O.1
-
39
-
-
76649089656
-
Selective serotonin reuptake inhibitors and breast cancer mortality in women receiving tamoxifen: A population based cohort study
-
Kelly, C.M. et al. Selective serotonin reuptake inhibitors and breast cancer mortality in women receiving tamoxifen: a population based cohort study. BMJ 340, c693 (2010).
-
(2010)
BMJ
, vol.340
-
-
Kelly, C.M.1
-
40
-
-
74549184178
-
Risk of breast cancer recurrence in women initiating tamoxifen with CYP2D6 inhibitors
-
abstr CRA508
-
A ubert, R.E. et al. Risk of breast cancer recurrence in women initiating tamoxifen with CYP2D6 inhibitors. J Clin Oncol 27, 9s abstr CRA508 (2009).
-
(2009)
J Clin Oncol
, vol.27
-
-
Aubert, R.E.1
-
41
-
-
77955297110
-
Electronic medical records for discovery research in rheumatoid arthritis
-
Liao, K.P. et al. Electronic medical records for discovery research in rheumatoid arthritis. Arthritis Care Res. (Hoboken). 62, 1120-1127 (2010).
-
(2010)
Arthritis Care Res. (Hoboken)
, vol.62
, pp. 1120-1127
-
-
Liao, K.P.1
-
42
-
-
34548399738
-
Cytochrome P450 2D6 genotype variation and venlafaxine dosage
-
McAlpine, D.E., O'Kane, D.J., Black, J.L. & Mrazek, D.A. Cytochrome P450 2D6 genotype variation and venlafaxine dosage. Mayo Clin. Proc. 82, 1065-1068 (2007).
-
(2007)
Mayo Clin. Proc.
, vol.82
, pp. 1065-1068
-
-
McAlpine, D.E.1
O'Kane, D.J.2
Black, J.L.3
Mrazek, D.A.4
-
43
-
-
4143049054
-
Lipid-lowering response to statins is affected by CYP3A5 polymorphism
-
Kivistö, K.T. et al. Lipid-lowering response to statins is affected by CYP3A5 polymorphism. Pharmacogenetics 14, 523-525 (2004).
-
(2004)
Pharmacogenetics
, vol.14
, pp. 523-525
-
-
Kivistö, K.T.1
-
44
-
-
41149174566
-
Variation in the 3-hydroxyl-3-methylglutaryl coenzyme a reductase gene is associated with racial differences in low-density lipoprotein cholesterol response to simvastatin treatment
-
Krauss, R.M. et al. Variation in the 3-hydroxyl-3-methylglutaryl coenzyme a reductase gene is associated with racial differences in low-density lipoprotein cholesterol response to simvastatin treatment. Circulation 117, 1537-1544 (2008).
-
(2008)
Circulation
, vol.117
, pp. 1537-1544
-
-
Krauss, R.M.1
-
45
-
-
77952390550
-
Anonymization of electronic medical records for validating genome-wide association studies
-
Loukides, G., Gkoulalas-Divanis, A. & Malin, B. Anonymization of electronic medical records for validating genome-wide association studies. Proc. Natl. Acad. Sci. USA 107, 7898-7903 (2010).
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 7898-7903
-
-
Loukides, G.1
Gkoulalas-Divanis, A.2
Malin, B.3
-
46
-
-
33751414347
-
Status of clinical gene sequencing data reporting and associated risks for information loss
-
Mitchell, D.R. & Mitchell, J.A. Status of clinical gene sequencing data reporting and associated risks for information loss. J. Biomed. Inform. 40, 47-54 (2007).
-
(2007)
J. Biomed. Inform.
, vol.40
, pp. 47-54
-
-
Mitchell, D.R.1
Mitchell, J.A.2
-
47
-
-
37349037641
-
Patients' and healthcare professionals' views on pharmacogenetic testing and its future delivery in the NHS
-
Fargher, E.A. et al. Patients' and healthcare professionals' views on pharmacogenetic testing and its future delivery in the NHS. Pharmacogenomics 8, 1511-1519 (2007).
-
(2007)
Pharmacogenomics
, vol.8
, pp. 1511-1519
-
-
Fargher, E.A.1
-
48
-
-
2942612302
-
Using genomics to help predict drug interactions
-
Gardner, D. Using genomics to help predict drug interactions. J. Biomed. Inform. 37, 139-146 (2004).
-
(2004)
J. Biomed. Inform.
, vol.37
, pp. 139-146
-
-
Gardner, D.1
-
49
-
-
77951575481
-
Use of information technology in medication reconciliation: A scoping review
-
Bassi, J., Lau, F. & Bardal, S. Use of information technology in medication reconciliation: a scoping review. Ann. Pharmacother. 44, 885-897 (2010).
-
(2010)
Ann. Pharmacother.
, vol.44
, pp. 885-897
-
-
Bassi, J.1
Lau, F.2
Bardal, S.3
-
50
-
-
41049092271
-
The tell-tale heart: Population-based surveillance reveals an association of rofecoxib and celecoxib with myocardial infarction
-
Brownstein, J.S., Sordo, M., Kohane, I.S. & Mandl, K.D. The tell-tale heart: population-based surveillance reveals an association of rofecoxib and celecoxib with myocardial infarction. PLoS ONE 2, e840 (2007).
-
(2007)
PLoS ONE
, vol.2
-
-
Brownstein, J.S.1
Sordo, M.2
Kohane, I.S.3
Mandl, K.D.4
|