-
1
-
-
0003462242
-
-
UNAIDS Accessed February 23, 2011
-
UNAIDS Report on the Global AIDS Epidemic. http://www.unaids.org/ globalreport/Global-report.htm. Accessed February 23, 2011.
-
Report on the Global AIDS Epidemic
-
-
-
2
-
-
78650303722
-
Pharmacogenomics: Will the promise be fulfilled?
-
Altman RB, Kroemer HK, McCarty CA, Ratain MJ, Roden D. Pharmacogenomics: will the promise be fulfilled? Nat Rev Genet. 2010;12:69-73.
-
(2010)
Nat Rev Genet
, vol.12
, pp. 69-73
-
-
Altman, R.B.1
Kroemer, H.K.2
McCarty, C.A.3
Ratain, M.J.4
Roden, D.5
-
3
-
-
0037197044
-
Genetic variations in HLA-B region and hypersensitivity reactions to abacavir
-
DOI 10.1016/S0140-6736(02)08158-8
-
Hetherington S, Hughes AR, Mosteller M, et al. Genetic variations in HLA-B region and hypersensitivity reactions to abacavir. Lancet. 2002;359:1121-1122. (Pubitemid 34270738)
-
(2002)
Lancet
, vol.359
, Issue.9312
, pp. 1121-1122
-
-
Hetherington, S.1
Hughes, A.R.2
Mosteller, M.3
Shortino, D.4
Baker, K.L.5
Spreen, W.6
Lai, E.7
Davies, K.8
Handley, A.9
Dow, D.J.10
Fling, M.E.11
Stocum, M.12
Bowman, C.13
Thurmond, L.M.14
Roses, A.D.15
-
4
-
-
0037006623
-
Association between presence of HLA-B 5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir
-
DOI 10.1016/S0140-6736(02)07873-X
-
Mallal S, Nolan D, Witt C, et al. Association between presence of HLA-B 5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir. Lancet. 2002;359:727-732. (Pubitemid 34215071)
-
(2002)
Lancet
, vol.359
, Issue.9308
, pp. 727-732
-
-
Mallal, S.1
Nolan, D.2
Witt, C.3
Masel, G.4
Martin, A.M.5
Moore, C.6
Sayer, D.7
Castley, A.8
Mamotte, C.9
Maxwell, D.10
James, I.11
Christiansen, F.T.12
-
5
-
-
42549131532
-
High sensitivity of human leukocyte antigen-B5701 as a marker for immunologically confirmed abacavir hypersensitivity in white and black patients
-
DOI 10.1086/529382
-
Saag M, Balu R, Phillips E, et al. High sensitivity of human leukocyte antigen-b5701 as a marker for immunologically confirmed abacavir hypersensitivity in white and black patients. Clin Infect Dis. 2008;46:1111-1118. (Pubitemid 351589880)
-
(2008)
Clinical Infectious Diseases
, vol.46
, Issue.7
, pp. 1111-1118
-
-
Saag, M.S.1
Balu, R.2
Phillips, E.3
Brachman, P.4
Martorell, C.5
Burman, W.6
Stancil, B.7
Mosteller, M.8
Brothers, C.9
Wannamaker, P.10
Hughes, A.11
Sutherland-Phillips, D.12
Mallal, S.13
Shaefer, M.14
-
6
-
-
38949196447
-
HLA-B5701 screening for hypersensitivity to abacavir
-
DOI 10.1056/NEJMoa0706135
-
Mallal S, Phillips E, Carosi G, et al. HLA-B5701 screening for hypersensitivity to abacavir. N Engl J Med. 2008;358:568-579. (Pubitemid 351214284)
-
(2008)
New England Journal of Medicine
, vol.358
, Issue.6
, pp. 568-579
-
-
Mallal, S.1
Phillips, E.2
Carosi, G.3
Molina, J.-M.4
Workman, C.5
Tomazie, J.6
Jagel-Guedes, E.7
Rugina, S.8
Kozyrev, O.9
Cid, J.F.10
Hay, P.11
Nolan, D.12
Hughes, S.13
Hughes, A.14
Ryan, S.15
Fitch, N.16
Thorborn, D.17
Benbow, A.18
-
8
-
-
19944428456
-
Pharmacogenetics of efavirenz and central nervous system side effects: An Adult AIDS Clinical Trials Group study
-
Haas DW, Ribaudo HJ, Kim RB, et al. Pharmacogenetics of efavirenz and central nervous system side effects: an Adult AIDS Clinical Trials Group study. AIDS. 2004;18:2391-2400. (Pubitemid 40065906)
-
(2004)
AIDS
, vol.18
, Issue.18
, pp. 2391-2400
-
-
Haas, D.W.1
Ribaudo, H.J.2
Kim, R.B.3
Tierney, C.4
Wilkinson, G.R.5
Gulick, R.M.6
Clifford, D.B.7
Hulgan, T.8
Marzolini, C.9
Acosta, E.P.10
-
9
-
-
20244364148
-
Influence of CYP2B6 polymorphism on plasma and intracellular concentrations and toxicity of efavirenz and nevirapine in HIV-infected patients
-
Rotger M, Colombo S, Furrer H, et al. Influence of CYP2B6 polymorphism on plasma and intracellular concentrations and toxicity of efavirenz and nevirapine in HIV-infected patients. Pharmacogenet Genomics. 2005;15:1-5. (Pubitemid 43205520)
-
(2005)
Pharmacogenetics and Genomics
, vol.15
, Issue.1
, pp. 1-5
-
-
Rotger, M.1
Colombo, S.2
Furrer, H.3
Bleiber, G.4
Buclin, T.5
Lee, B.L.6
Keiser, O.7
Biollaz, J.8
Decosterd, L.9
Telenti, A.10
Battegay, M.11
Bernard, M.-C.12
Bernasconi, E.13
Bucher, H.14
Burgisser, Ph.15
Egger, M.16
Erb, P.17
Fierz, W.18
Flepp, M.19
Francioli, P.20
Furrer, H.J.21
Gorgievski, M.22
Gunthard, H.23
Grob, P.24
Hirschel, B.25
Kind, C.26
Klimkait, Th.27
Ledergerber, B.28
Lauper, U.29
Opravil, M.30
Paccaud, F.31
Pantaleo, G.32
Perrin, L.33
Piffaretti, J.-C.34
Rickenbach, M.35
Rudin, C.36
Schupbach, J.37
Vernazza, P.38
Wagels, Th.39
Weber, R.40
more..
-
10
-
-
27944460707
-
Pharmacogenetics of long-term responses to antiretroviral regimens containing efavirenz and/or nelfinavir: An adult AIDS clinical trials group study
-
DOI 10.1086/497610
-
Haas DW, Smeaton LM, Shafer RW, et al. Pharmacogenetics of long-term responses to antiretroviral regimens containing efavirenz and/or nelfi navir: an Adult AIDS Clinical Trials Group Study. J Infect Dis. 2005;192:1931-42. (Pubitemid 41681891)
-
(2005)
Journal of Infectious Diseases
, vol.192
, Issue.11
, pp. 1931-1942
-
-
Haas, D.W.1
Smeaton, L.M.2
Shafer, R.W.3
Robbins, G.K.4
Morse, G.D.5
Labbe, L.6
Wilkinson, G.R.7
Clifford, D.B.8
D'Aquila, R.T.9
De Gruttola, V.10
Pollard, R.B.11
Merigan, T.C.12
Hirsch, M.S.13
George Jr., A.L.14
Donahue, J.P.15
Kim, R.B.16
-
11
-
-
33644588715
-
Identification of a novel specifi c CYP2B6 allele in Africans causing impaired metabolism of the HIV drug efavirenz
-
Wang J, Sonnerborg A, Rane A, et al. Identification of a novel specifi c CYP2B6 allele in Africans causing impaired metabolism of the HIV drug efavirenz. Pharmacogenet Genomics. 2006;16:191-198.
-
(2006)
Pharmacogenet Genomics
, vol.16
, pp. 191-198
-
-
Wang, J.1
Sonnerborg, A.2
Rane, A.3
-
12
-
-
33947382259
-
Predictive value of known and novel alleles of CYP2B6 for efavirenz plasma concentrations in HIV-infected individuals
-
DOI 10.1038/sj.clpt.6100072, PII 6100072
-
Rotger M, Tegude H, Colombo S, et al. Predictive value of known and novel alleles of CYP2B6 for efavirenz plasma concentrations in HIV-infected individuals. Clin Pharmacol Ther. 2007;81:557-566. (Pubitemid 46454205)
-
(2007)
Clinical Pharmacology and Therapeutics
, vol.81
, Issue.4
, pp. 557-566
-
-
Rotger, M.1
Tegude, H.2
Colombo, S.3
Cavassini, M.4
Furrer, H.5
Decosterd, L.6
Blievernicht, J.7
Saussele, T.8
Gunthard, H.F.9
Schwab, M.10
Eichelbaum, M.11
Telenti, A.12
Zanger, U.M.13
Battegay, M.14
Bernard, M.-C.15
Bernasconi, E.16
Bucher, H.17
Burgisser, Ph.18
Egger, M.19
Erb, P.20
Fierz, W.21
Flepp, M.22
Francioli, P.23
Furrer, H.J.24
Gorgievski, M.25
Gunthard, H.26
Grob, P.27
Hirschel, B.28
Kind, C.29
Klimkait, Th.30
Ledergerber, B.31
Lauper, U.32
Opravil, M.33
Paccaud, F.34
Pantaleo, G.35
Perrin, L.36
Piffaretti, J.-C.37
Rickenbach, M.38
Rudin, C.39
Schupbach, J.40
Telenti, A.41
Vernazza, P.42
Wagels, Th.43
Weber, R.44
more..
-
13
-
-
77955685573
-
Effect of CYP2B6, ABCB1, and CYP3A5 polymorphisms on efavirenz pharmacokinetics and treatment response: An AIDS Clinical Trials Group study
-
Ribaudo HJ, Liu H, Schwab M, et al. Effect of CYP2B6, ABCB1, and CYP3A5 polymorphisms on efavirenz pharmacokinetics and treatment response: an AIDS Clinical Trials Group study. J Infect Dis. 2010;202:717-722.
-
(2010)
J Infect Dis
, vol.202
, pp. 717-722
-
-
Ribaudo, H.J.1
Liu, H.2
Schwab, M.3
-
14
-
-
12144260460
-
Predisposition to nevirapine hypersensitivity associated with HLA-DRB10101 and abrogated by low CD4 T-cell counts
-
Martin AM, Nolan D, James I, et al. Predisposition to nevirapine hypersensitivity associated with HLADRB10101 and abrogated by low CD4 T-cell counts. AIDS. 2005;19:97-99. (Pubitemid 40111026)
-
(2005)
AIDS
, vol.19
, Issue.1
, pp. 97-99
-
-
Martin, A.M.1
Nolan, D.2
James, I.3
Cameron, P.4
Keller, J.5
Moore, C.6
Phillips, E.7
Christiansen, F.T.8
Mallal, S.9
-
15
-
-
77954378516
-
HLACw04 allele associated with nevirapine-induced rash in HIV-infected Thai patients
-
Likanonsakul S, Rattanatham T, Feangvad S, et al. HLACw04 allele associated with nevirapine-induced rash in HIV-infected Thai patients. AIDS Res Ther. 2009;6:22-28.
-
(2009)
AIDS Res Ther
, vol.6
, pp. 22-28
-
-
Likanonsakul, S.1
Rattanatham, T.2
Feangvad, S.3
-
16
-
-
59549096348
-
HLA-B3505 allele is a strong predictor for nevirapineinduced skin adverse drug reactions in HIV-infected Thai patients
-
Chantarangsu S, Mushiroda T, Mahasirimongkol S, et al. HLA-B3505 allele is a strong predictor for nevirapineinduced skin adverse drug reactions in HIV-infected Thai patients. Pharmacogenet Genomics. 2009;19:139-146.
-
(2009)
Pharmacogenet Genomics
, vol.19
, pp. 139-146
-
-
Chantarangsu, S.1
Mushiroda, T.2
Mahasirimongkol, S.3
-
17
-
-
39849105346
-
HLA-DRB101 associated with cutaneous hypersensitivity induced by nevirapine and efavirenz
-
DOI 10.1097/QAD.0b013e3282f37812, PII 0000203020080219000015
-
Vitezica ZG, Milpied B, Lonjou C, et al. HLA-DRB101 associated with cutaneous hypersensitivity induced by nevirapine and efavirenz. AIDS. 2008;22:540-541. (Pubitemid 351317299)
-
(2008)
AIDS
, vol.22
, Issue.4
, pp. 540-541
-
-
Vitezica, Z.G.1
Milpied, B.2
Lonjou, C.3
Borot, N.4
Ledger, T.N.5
Lefebvre, A.6
Hovnanian, A.7
-
18
-
-
77950787858
-
ADME pharmacogenetics: Investigation of the pharmacokinetics of the antiretroviral agent lopinavir coformulated with ritonavir
-
Lubomirov R, di Iulio J, Fayet A, et al. ADME pharmacogenetics: investigation of the pharmacokinetics of the antiretroviral agent lopinavir coformulated with ritonavir. Pharmacogenet Genomics. 2010;20:217-230.
-
(2010)
Pharmacogenet Genomics
, vol.20
, pp. 217-230
-
-
Lubomirov, R.1
Di Iulio, J.2
Fayet, A.3
-
19
-
-
75649091119
-
HIV protease inhibitors are substrates for OATP1A2 OATP1B1 and OATP1B3 and lopinavir plasma concentrations are Influenced by SLCO1B1 polymorphisms
-
Hartkoorn RC, Kwan WS, Shallcross V, et al. HIV protease inhibitors are substrates for OATP1A2, OATP1B1 and OATP1B3 and lopinavir plasma concentrations are Influenced by SLCO1B1 polymorphisms. Pharmacogenet Genomics. 2010;20:112-120.
-
(2010)
Pharmacogenet Genomics
, vol.20
, pp. 112-120
-
-
Hartkoorn, R.C.1
Kwan, W.S.2
Shallcross, V.3
-
20
-
-
67349205036
-
Pharmacogenetics-based population pharmacokinetic analysis of efavirenz in HIV-1-infected individuals
-
Arab-Alameddine M, Di Iulio J, Buclin T, et al. Pharmacogenetics-based population pharmacokinetic analysis of efavirenz in HIV-1-infected individuals. Clin Pharmacol Ther. 2009;85:485-494.
-
(2009)
Clin Pharmacol Ther
, vol.85
, pp. 485-494
-
-
Arab-Alameddine, M.1
Di Iulio, J.2
Buclin, T.3
-
21
-
-
77449143922
-
Contribution of genomewide significant single-nucleotide polymorphisms and antiretroviral therapy to dyslipidemia in HIV-infected individuals: A longitudinal study
-
Rotger M, Bayard C, Taffe P, et al. Contribution of genomewide significant single-nucleotide polymorphisms and antiretroviral therapy to dyslipidemia in HIV-infected individuals: a longitudinal study. Circ Cardiovasc Genet. 2009;2:621-628.
-
(2009)
Circ Cardiovasc Genet
, vol.2
, pp. 621-628
-
-
Rotger, M.1
Bayard, C.2
Taffe, P.3
-
22
-
-
77958529496
-
Impact of single nucleotide polymorphisms and of clinical risk factors on new-onset diabetes mellitus in HIV-infected individuals
-
Rotger M, Gsponer T, Martinez R, et al. Impact of single nucleotide polymorphisms and of clinical risk factors on new-onset diabetes mellitus in HIV-infected individuals. Clin Infect Dis. 2010;51:1090-1098.
-
(2010)
Clin Infect Dis
, vol.51
, pp. 1090-1098
-
-
Rotger, M.1
Gsponer, T.2
Martinez, R.3
-
23
-
-
70349292099
-
Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance
-
Ge D, Fellay J, Thompson AJ, et al. Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance. Nature. 2009;461:399-401.
-
(2009)
Nature
, vol.461
, pp. 399-401
-
-
Ge, D.1
Fellay, J.2
Thompson, A.J.3
-
24
-
-
49949093313
-
Development of a large-scale de-identified DNA biobank to enable personalized medicine
-
Roden DM, Pulley JM, Basford MA, et al. Development of a large-scale de-identified DNA biobank to enable personalized medicine. Clin Pharmacol Ther. 2008;84: 362-369.
-
(2008)
Clin Pharmacol Ther
, vol.84
, pp. 362-369
-
-
Roden, D.M.1
Pulley, J.M.2
Basford, M.A.3
-
25
-
-
0035940414
-
Mechanism of indinavir-induced hyperbilirubinemia
-
DOI 10.1073/pnas.231140698
-
Zucker SD, Qin X, Rouster SD, et al. Mechanism of indinavir-induced hyperbilirubinemia. Proc Natl Acad Sci USA. 2001;98:12671-12676. (Pubitemid 33020004)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.22
, pp. 12671-12676
-
-
Zucker, S.D.1
Qin, X.2
Rouster, S.D.3
Yu, F.4
Green, R.M.5
Keshavan, P.6
Feinberg, J.7
Sherman, K.E.8
-
26
-
-
84255204998
-
Population pharmacodynamic assessment of atazanavir exposure uridine diphosphate-glucuronosyl transferase (UGT) 1A1 genotype and safety in healthy subjects [abstract 3051]
-
Washington DC: American Society for Microbiology
-
O'Mara, et al. Population pharmacodynamic assessment of atazanavir exposure uridine diphosphate-glucuronosyl transferase (UGT) 1A1 genotype and safety in healthy subjects [abstract 3051]. In: Program and abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy (Chicago) Washington DC: American Society for Microbiology 2003.
-
(2003)
41st Interscience Conference on Antimicrobial Agents and Chemotherapy (Chicago
-
-
O'Mara, E.1
-
27
-
-
25844446183
-
Gilbert syndrome and the development of antiretroviral therapy-associated hyperbilirubinemia
-
DOI 10.1086/466531
-
Rotger M, Taffe P, Bleiber G, et al. Gilbert syndrome and the development of antiretroviral therapy-associated hyperbilirubinemia. J Infect Dis. 2005;192:1381-1386. (Pubitemid 41401151)
-
(2005)
Journal of Infectious Diseases
, vol.192
, Issue.8
, pp. 1381-1386
-
-
Rotger, M.1
Taffe, P.2
Bleiber, G.3
Gunthard, H.F.4
Furrer, H.5
Vernazza, P.6
Drechsler, H.7
Bernasconi, E.8
Rickenbach, M.9
Telenti, A.10
-
28
-
-
72949097439
-
The impact of SLCO1B1 polymorphisms on the plasma concentration of lopinavir and ritonavir in HIV-infected men
-
Kohlrausch FB, de Cassia Estrela R, Barroso PF and Suarez-Kurtz G. The impact of SLCO1B1 polymorphisms on the plasma concentration of lopinavir and ritonavir in HIV-infected men. Br J Clin Pharmacol. 2010;69:95-98.
-
(2010)
Br J Clin Pharmacol
, vol.69
, pp. 95-98
-
-
Kohlrausch, F.B.1
De Cassia Estrela, R.2
Barroso, P.F.3
Suarez-Kurtz, G.4
-
30
-
-
37349034567
-
CYP2B6 genetic variants are associated with nevirapine pharmacokinetics and clinical response in HIV-1-infected children
-
DOI 10.1097/QAD.0b013e3282ef9695, PII 0000203020071018000009
-
Saitoh A, Sarles E, Capparelli E, et al. CYP2B6 genetic variants are associated with nevirapine pharmacokinetics and clinical response in HIV-1-infected children. AIDS. 2007;21:2191-2199. (Pubitemid 350287217)
-
(2007)
AIDS
, vol.21
, Issue.16
, pp. 2191-2199
-
-
Saitoh, A.1
Sarles, E.2
Capparelli, E.3
Aweeka, F.4
Kovacs, A.5
Burchett, S.K.6
Wiznia, A.7
Nachman, S.8
Fenton, T.9
Spector, S.A.10
-
31
-
-
73549117428
-
Influence of CYP2B6 polymorphisms on the persistence of plasma nevirapine concentrations following a single intra-partum dose for the prevention of mother to child transmission in HIV-infected Thai women
-
Chantarangsu S, Cressey TR, Mahasirimongkol S, et al. Influence of CYP2B6 polymorphisms on the persistence of plasma nevirapine concentrations following a single intra-partum dose for the prevention of mother to child transmission in HIV-infected Thai women. J Antimicrob Chemother. 2009;64:1265-1273.
-
(2009)
J Antimicrob Chemother
, vol.64
, pp. 1265-1273
-
-
Chantarangsu, S.1
Cressey, T.R.2
Mahasirimongkol, S.3
-
32
-
-
65449118348
-
Cytochrome P450 2B6 516G T is associated with plasma concentrations of nevirapine at both 200 mg twice daily and 400 mg once daily in an ethnically diverse population
-
Mahungu T, Smith C, Turner F, et al. Cytochrome P450 2B6 516G T is associated with plasma concentrations of nevirapine at both 200 mg twice daily and 400 mg once daily in an ethnically diverse population. HIV Med. 2009;10:310-317.
-
(2009)
HIV Med
, vol.10
, pp. 310-317
-
-
Mahungu, T.1
Smith, C.2
Turner, F.3
-
33
-
-
20244375708
-
Modeling the influence of APOC3, APOE, and TNF polymorphisms on the risk of antiretroviral therapy-associated lipid disorders
-
DOI 10.1086/429295
-
Tarr PE, Taffe P, Bleiber G, et al. Modeling the Influence of APOC3, APOE, and TNF polymorphisms on the risk of antiretroviral therapy-associated lipid disorders. J Infect Dis. 2005;191:1419-1426. (Pubitemid 40563352)
-
(2005)
Journal of Infectious Diseases
, vol.191
, Issue.9
, pp. 1419-1426
-
-
Tarr, P.E.1
Taffe, P.2
Bleiber, G.3
Furrer, H.4
Rotger, M.5
Martinez, R.6
Hirschel, B.7
Battegay, M.8
Weber, R.9
Vernazza, P.10
Bernasconi, E.11
Darioli, R.12
Rickenbach, M.13
Ledergerber, B.14
Telenti, A.15
-
34
-
-
33645329876
-
Associations among race/ethnicity ApoC-III genotypes and lipids in HIV-1-infected individuals on antiretroviral therapy
-
Foulkes AS, Wohl DA, Frank I, et al. Associations among race/ethnicity, ApoC-III genotypes, and lipids in HIV-1-infected individuals on antiretroviral therapy. PLoS Med. 2006;3:e52.
-
(2006)
PLoS Med
, vol.3
-
-
Foulkes, A.S.1
Wohl, D.A.2
Frank, I.3
|