Paeoniflorin of Paeonia lactiflora prevents renal interstitial fibrosis induced by unilateral ureteral obstruction in mice

Phytomedicine

Volumn 20, Issue 8-9, 2013, Pages 753-759

  Zeng, Junnan ^a   Dou, Yannong ^a   Guo, Jiaomei ^a   Wu, Xin ^a   Dai, Yue ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

BMP 7; Epithelial mesenchymal transition; Paeonia lactiflora; Paeoniflorin; Renal fibrosis; TGF 1; Unilateral ureteral obstruction

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ANTIFIBROTIC AGENT; COLLAGEN TYPE 1; COLLAGEN TYPE 3; HYDROXYPROLINE; LOSARTAN; MESSENGER RNA; OSTEOGENIC PROTEIN 1; PAEONIA LACTIFLORA EXTRACT; PAEONIFLORIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSCRIPTION FACTOR SNAIL; TRANSFORMING GROWTH FACTOR BETA1; UVOMORULIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; EPITHELIAL MESENCHYMAL TRANSITION; EXTRACELLULAR MATRIX; HISTOPATHOLOGY; KIDNEY FIBROSIS; MALE; MOUSE; NONHUMAN; PAEONIA LACTIFLORA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TREATMENT DURATION; URETER OBSTRUCTION;

ANIMALS; BENZOATES; BONE MORPHOGENETIC PROTEIN 7; BRIDGED COMPOUNDS; COLLAGEN; DOWN-REGULATION; EPITHELIAL-MESENCHYMAL TRANSITION; FIBROSIS; GENE EXPRESSION REGULATION; GLUCOSIDES; KIDNEY DISEASES; MALE; MICE; MICE, INBRED ICR; PAEONIA; PHOSPHORYLATION; PLASMINOGEN ACTIVATOR INHIBITOR 1; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; URETERAL OBSTRUCTION;

EID: 84878088445     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2013.02.010     Document Type: Article

References (30)

1. E.P. Böttinger, and M. Bitzer TGF-beta signaling in renal disease Journal of the American Society of Nephrology 13 2002 2600 2610
2. R.M. Carew, B. Wang, and P. Kantharidis The role of EMT in renal fibrosis Cell and Tissue Research 347 2012 103 116
3. R.L. Chevalier, M.S. Forbes, and B.A. Thornhill Ureteral obstruction as a model of renal interstitial fibrosis and obstructive nephropathy Kidney International 75 2009 1145 1152
4. M.H. Cho Renal fibrosis Korean Journal of Pediatrics 53 2010 735 740
5. J. Coresh, E. Selvin, L.A. Stevens, J. Manzi, J.W. Kusek, and P. Eggers Prevalence of chronic kidney disease in the United States Journal of the American Medical Association 298 2007 2038 2047
6. M.J. Damião, A.P. Bertocchi, R.M. Monteiro, G.M. Gonçalves, M.A. Cenedeze, and C.Q. Feitoza The effects of rapamycin in the progression of renal fibrosis Transplantation Proceedings 39 2007 457 459
7. P.E. de Jong, M. van der Velde, R.T. Gansevoort, and C. Zoccali Screening for chronic kidney disease: where does Europe go? Clinical Journal of the American Society of Nephrology 3 2008 616 623
8. A.A. Eddy Molecular basis of renal fibrosis Pediatric Nephrology 15 2000 290 301
9. A.K. Ghosh, and D.E. Vaughan PAI-1 in tissue fibrosis Journal of Cellular Physiology 227 2012 493 507
10. R. Hirschberg Wound healing in the kidney: complex interactions in renal interstitial fibrogenesis Journal of the American Society of Nephrology 16 2005 9 11
11. H.Y. Lan, and A.C. Chung TGF-β/Smad signaling in kidney disease Seminars in Nephrology 32 2012 236 243
12. X. Li, J. Shen, Z. Zhong, H. Wen, Q. Luo, and W. Wei Paeoniflorin: a monomer from traditional Chinese medical herb ameliorates Schistosoma japonicum egg-induced hepatic fibrosis in mice Journal of Parasitology 95 2009 1520 1524
13. D.F. Liu, W. Wei, and L.H. Song Protective effect of paeoniflorin on immunological liver injury induced by bacillus Calmette-Guerin plus lipopolysaccharide: modulation of tumour necrosis factor-alpha and interleukin-6 MRNA Clinical and Experimental Pharmacology and Physiology 33 2006 332 339
14. Y. Liu New insights into epithelial-mesenchymal transition in kidney fibrosis Journal of the American Society of Nephrology 21 2010 212 222
15. J.M. López-Novoa, A.B. Rodríguez-Peña, A. Ortiz, C. Martínez-Salgado, and F.J. López Hernández Etiopathology of chronic tubular, glomerular and renovascular nephropathies: clinical implications Journal of Translational Medicine 9 2011 13
16. S.R. Manson, R.A. Niederhoff, K.A. Hruska, and P.F. Austin Endogenous BMP-7 is a critical molecular determinant of the reversibility of obstruction-induced renal injuries American Journal of Physiology. Renal Physiology 301 2011 F1293 F1300
17. S.R. Manson, R.A. Niederhoff, K.A. Hruska, and P.F. Austin The BMP-7-Smad1/5/8 pathway promotes kidney repair after obstruction induced renal injury Journal of Urology 185 2011 2523 2530
18. J. Massagué, and Y.G. Chen Controlling TGF-beta signaling Genes and Development 14 2000 627 644
19. S. Meran, and R. Steadman Fibroblasts and myofibroblasts in renal fibrosis International Journal of Experimental Pathology 92 2011 158 167
20. J. Morrissey, K. Hruska, G. Guo, S. Wang, Q. Chen, and S. Klahr Bone morphogenetic protein-7 improves renal fibrosis and accelerates the return of renal function Journal of the American Society of Nephrology 13 Suppl. 1 2002 S14 S21
21. J.J. Morrissey, and S. Klahr Effect of AT2 receptor blockade on the pathogenesis of renal fibrosis American Journal of Physiology 276 1999 F39 F45
22. M.P. Rastaldi, F. Ferrario, L. Giardino, G. Dell'Antonio, C. Grillo, and P. Grillo Epithelial-mesenchymal transition of tubular epithelial cells in human renal biopsies Kidney International 62 2002 137 146
23. M. Sato, Y. Muragaki, S. Saika, A.B. Roberts, and A. Ooshima Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction Journal of Clinical Investigation 112 2003 1486 1494
24. A. Schieppati, and G. Remuzzi Chronic renal diseases as a public health problem: epidemiology, social, and economic implications Kidney International. Supplement 2005 S7 S10
25. N. Wang, J. Lapage, and R. Hirschberg Loss of tubular bone morphogenetic protein-7 in diabetic nephropathy Journal of the American Society of Nephrology 12 2001 2392 2399
26. H.Y. Yu, M.G. Liu, D.N. Liu, G.W. Shang, Y. Wang, and C. Qi Antinociceptive effects of systemic paeoniflorin on bee venom-induced various 'phenotypes' of nociception and hypersensitivity Pharmacology Biochemistry and Behavior 88 2007 131 140
27. M. Zeisberg, J. Hanai, H. Sugimoto, T. Mammoto, D. Charytan, and F. Strutz BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury Nature Medicine 9 2003 964 968
28. M. Zeisberg, and R. Kalluri Experimental strategies to reverse chronic renal disease Blood Purification 22 2004 440 445
29. Y.Q. Zheng, W. Wei, L. Zhu, and J.X. Liu Effects and mechanisms of Paeoniflorin, a bioactive glucoside from paeony root, on adjuvant arthritis in rats Inflammation Research 56 2007 182 188
30. H. Zhou, D. Bian, X. Jiao, Z. Wei, H. Zhang, and Y. Xia Paeoniflorin protects against lipopolysaccharide-induced acute lung injury in mice by alleviating inflammatory cell infiltration and microvascular permeability Inflammation Research 60 2011 981 990