Development of a highly sensitive three-dimensional gel electrophoresis method for characterization of monoclonal protein heterogeneity

Analytical Biochemistry

Volumn 438, Issue 2, 2013, Pages 117-123

  Nakano, Keiichi ^a   Tamura, Shogo ^b,c   Otuka, Kohei ^b   Niizeki, Noriyasu ^b,d   Shigemura, Masahiko ^a   Shimizu, Chikara ^a   Matsuno, Kazuhiko ^a   Kobayashi, Seiichi ^b   Moriyama, Takanori ^b  

^a HOKKAIDO UNIVERSITY HOSPITAL   (Japan)

^b HOKKAIDO UNIVERSITY   (Japan)

^c JAPAN SOCIETY FOR THE PROMOTION OF SCIENCE   (Japan)

^d ASAHIKAWA MEDICAL COLLEGE   (Japan)

Author keywords

Heterogeneity; Monoclonal proteins; Three dimensional gel electrophoresis

Indexed keywords

PROTEINS; SODIUM CHLORIDE;

AGAROSE GEL; AGAROSE GEL ELECTROPHORESIS; CLINICAL SAMPLES; GEL ELECTROPHORESIS; HETEROGENEITY; ISOELECTRIC FOCUSING; PROTEIN RECOVERY; SDS PAGE;

ELECTROPHORESIS;

IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY; MONOCLONAL PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

AGAR GEL ELECTROPHORESIS; ARTICLE; CLINICAL ARTICLE; ELECTROPHORETIC MOBILITY; GEL ELECTROPHORESIS; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN POLYMORPHISM; PROTEIN PURIFICATION; THREE DIMENSIONAL GEL ELECTROPHORESIS; VALIDATION PROCESS;

EID: 84878068919     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2013.03.013     Document Type: Article

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