Nebivolol treatment improves resistant arterial function and reduces ventricular hypertrophy and angiotensin II in spontaneously hypertension rats

JRAAS - Journal of the Renin-Angiotensin-Aldosterone System

Volumn 14, Issue 2, 2013, Pages 146-155

  Wang, Yan ^a   Zhang, Ming Sheng ^a   Liu, Yu ^a  

^a SHANXI MEDICAL UNIVERSITY   (China)

Author keywords

femoral artery; Nebivolol; renal artery; renin angiotensin system (RAS); SHR

Indexed keywords

ACETYLCHOLINE; ANGIOTENSIN II; ATENOLOL; DIPEPTIDYL CARBOXYPEPTIDASE; ENDOTHELIN 1; NEBIVOLOL; NITROPRUSSIDE SODIUM; NORADRENALIN; POTASSIUM CHLORIDE; RENIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD VESSEL REACTIVITY; BODY WEIGHT; CONTROLLED STUDY; ENZYME ACTIVITY; FEMORAL ARTERY; HEART LEFT VENTRICLE HYPERTROPHY; KIDNEY ARTERY; NONHUMAN; PLASMA RENIN ACTIVITY; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SPONTANEOUSLY HYPERTENSIVE RAT; SYSTOLIC BLOOD PRESSURE;

FEMORAL ARTERY; NEBIVOLOL; RENAL ARTERY; RENIN-ANGIOTENSIN SYSTEM (RAS); SHR;

ACETYLCHOLINE; ANGIOTENSIN II; ANIMALS; BENZOPYRANS; BLOOD PRESSURE; BODY WEIGHT; ENDOTHELIN-1; ETHANOLAMINES; FEMORAL ARTERY; HYPERTROPHY, LEFT VENTRICULAR; MALE; NITROPRUSSIDE; NOREPINEPHRINE; RATS; RATS, INBRED SHR; RENAL ARTERY; RENIN-ANGIOTENSIN SYSTEM; SYSTOLE; VASCULAR RESISTANCE;

EID: 84878064679     PISSN: 14703203     EISSN: 17528976     Source Type: Journal    
DOI: 10.1177/1470320312470580     Document Type: Article

References (33)

1. Schiffrin EL. Reactivity of small blood vessels in hypertension: Relation with structural changes. State of the art lecture. Hypertension. 1992 ; 19: II1-9
2. Bohlen HG. Localization of vascular resistance changes during hypertension. Hypertension. 1986 ; 8: 181-183 (Pubitemid 16090630)
3. Rosivall L. Intrarenal renin-angiotensin system. Mol Cell Endocrinol. 2009 ; 302: 185-192
4. Lee MA, Paul M, Bohm M, et al. Effects of angiotensin-converting enzyme inhibitors on tissue renin-angiotensin systems. Am J Cardiol. 1992 ; 70: 12C - 19C
5. Verdecchia P, Angeli F, Mazzotta G, et al. The renin angiotensin system in the development of cardiovascular disease: Role of aliskiren in risk reduction. Vasc Health Risk Manag. 2008 ; 4: 971-981
6. Cockcroft J. A review of the safety and efficacy of nebivolol in the mildly hypertensive patient. Vasc Health Risk Manag. 2007 ; 3: 909-917
7. Weiss R. Nebivolol: A novel beta-blocker with nitric oxide-induced vasodilatation. Vasc Health Risk Manag. 2006 ; 2: 303-308 (Pubitemid 44275465)
8. Guerrero E, Voces F, Ardanaz N, et al. Long-term treatment with nebivolol improves arterial reactivity and reduces ventricular hypertrophy in spontaneously hypertensive rats. J Cardiovasc Pharmacol. 2003 ; 42: 348-355 (Pubitemid 37071690)
9. Angulo J, Wright HM, Cuevas P, et al. Nebivolol dilates human penile arteries and reverses erectile dysfunction in diabetic rats through enhancement of nitric oxide signaling. J Sex Med. 2010 ; 7: 2681-2697
10. Altwegg LA, d'Uscio LV, Barandier C, et al. Nebivolol induces NO-mediated relaxations of rat small mesenteric but not of large elastic arteries. J Cardiovasc Pharmacol. 2000 ; 36: 316-320 (Pubitemid 30660461)
11. Gorski TP, Campbell DJ. Angiotensin-converting enzyme determination in plasma during therapy with converting enzyme inhibitor: Two methods compared. Clin Chem. 1991 ; 37: 1390-1393 (Pubitemid 21925977)
12. Wong MS, Man RY, Vanhoutte PM. Calcium-independent phospholipase A(2) plays a key role in the endothelium-dependent contractions to acetylcholine in the aorta of the spontaneously hypertensive rat. Am J Physiol Heart Circ Physiol. 2010 ; 298: H1260 - H1266
13. Aalkjaer C, Heagerty AM, Petersen KK, et al. Evidence for increased media thickness, increased neuronal amine uptake, and depressed excitation - contraction coupling in isolated resistance vessels from essential hypertensives. Circ Res. 1987 ; 61: 181-186 (Pubitemid 17137117)
14. Izzard AS, Heagerty AM. Hypertension and the vasculature: Arterioles and the myogenic response. J Hypertens. 1995 ; 13: 1-4
15. Izzard AS, Bund SJ, Heagerty AM. Myogenic tone in mesenteric arteries from spontaneously hypertensive rats. Am J Physiol. 1996 ; 270: H1 - H6
16. Schmid-Schonbein GW, Zweifach BW, DeLano FA, et al. Microvascular tone in a skeletal muscle of spontaneously hypertensive rats. Hypertension. 1987 ; 9: 164-171 (Pubitemid 17027830)
17. Van Bortel LM, de Hoon JN, Kool MJ, et al. Pharmacological properties of nebivolol in man. Eur J Clin Pharmacol. 1997 ; 51: 379-384 (Pubitemid 27055905)
18. Leung JW, Wong WT, Koon HW, et al. Transgenic mice over-expressing ET-1 in the endothelial cells develop systemic hypertension with altered vascular reactivity. PloS One. 2011 ; 6: e26994
19. Uematsu N, Ogawa K, Tokinaga Y, et al. Sevoflurane inhibits angiotensin II-induced Rho kinase-mediated contraction of vascular smooth muscle from spontaneously hypertensive rat. J Anesth. 2011 ; 25: 398-404
20. Török J, Koprdová R, Cebová M, et al. Functional and structural pattern of arterial responses in hereditary hypertriglyceridemic and spontaneously hypertensive rats in early stage of experimental hypertension. Physiol Res. 2006 ; 55: S65 - S71
21. Hayakawa H, Hirata Y, Suzuki E, et al. Mechanisms for altered endothelium-dependent vasorelaxation in isolated kidneys from experimental hypertensive rats. Am J Physiol. 1993 ; 264: H1535 - H1541
22. Maffei A, Lembo G. Nitric oxide mechanisms of nebivolol. Ther Adv Cardiovasc Dis. 2009 ; 3: 317-327
23. Wang Y, Zhang M, Liu Y, et al. The effect of nebivolol on asymmetric dimethylarginine system in spontaneously hypertension rats. Vascul Pharmacol. 2011 ; 54: 36-43
24. Feng MG, Prieto MC, Navar LG. Nebivolol-induced vasodilation of renal afferent arterioles involves beta3-adrenergic receptor and nitric oxide synthase activation. Am J Physiol Renal Physiol. 2012 ; 303: F775 - F782
25. Grundt C, Meier K, Grundt A, et al. Evidence for an estradiol-agonistic action of nebivolol in spontaneously hypertensive rats. J Hypertens. 2007 ; 25: 1001-1007 (Pubitemid 46573119)
26. Wagenfeld L, Himpel O, Galambos P, et al. Protective effects of nebivolol on oxygen free radical-induced vasoconstrictions in vitro. Med Sci Monit. 2008 ; 14: BR109 - BR112
27. Mason RP, Kubant R, Jacob RF, et al. Effect of nebivolol on endothelial nitric oxide and peroxynitrite release in hypertensive animals: Role of antioxidant activity. J Cardiovasc Pharmacol. 2006 ; 48: 862-869 (Pubitemid 44276465)
28. Kobori H, Nangaku M, Navar LG, et al. The intrarenal renin-angiotensin system: From physiology to the pathobiology of hypertension and kidney disease. Pharmacol Rev. 2007 ; 59: 251-287 (Pubitemid 47481436)
29. Hollenberg NK, Fisher ND, Price DA. Pathways for angiotensin II generation in intact human tissue: Evidence from comparative pharmacological interruption of the renin system. Hypertension. 1998 ; 32: 387-392 (Pubitemid 28429123)
30. Padmanabhan N, Jardine AG, McGrath JC, et al. Angiotensin-converting enzyme-independent contraction to angiotensin I in human resistance arteries. Circulation. 1999 ; 99: 2914-2920 (Pubitemid 29258980)
31. Linz W, Wiemer G, Gohlke P, et al. Contribution of kinins to the cardiovascular actions of angiotensin-converting enzyme inhibitors. Pharmacol Rev. 1995 ; 47: 25-49
32. Zafari AM, Ushio-Fukai M, Akers M, et al. Role of NADH/NADPH oxidase-derived H2O2 in angiotensin II-induced vascular hypertrophy. Hypertension. 1998 ; 32: 488-495 (Pubitemid 28429138)
33. Dijkhorst-Oei LT, Stroes ES, Koomans HA, et al. Acute simultaneous stimulation of nitric oxide and oxygen radicals by angiotensin II in humans in vivo. J Cardiovasc Pharmacol. 1999 ; 33: 420-424 (Pubitemid 29101986)