Overexpression of cAMP-response element modulator causes abnormal growth and development of the atrial myocardium resulting in a substrate for sustained atrial fibrillation in mice

International Journal of Cardiology

Volumn 166, Issue 2, 2013, Pages 366-374

  Kirchhof, Paulus ^a,b   Marijon, Eloi ^c,d   Fabritz, Larissa ^a,b   Li, Na ^e   Wang, Wei ^e   Wang, Tiannan ^e   Schulte, Kirsten ^f   Hanstein, Juliane ^f   Schulte, Jan S ^f   Vogel, Mathis ^a,b   Mougenot, Nathalie ^c,d   Laakmann, Sandra ^a,b   Fortmueller, Lisa ^a,b   Eckstein, Jens ^g   Verheule, Sander ^g   Kaese, Sven ^a,b   Staab, Ariane ^f   Grote Wessels, Stephanie ^f   Schotten, Ulrich ^b,g   Moubarak, Ghassan ^c,d   Wehrens, Xander H T ^e   Schmitz, Wilhelm ^f   Hatem, Stéphane ^c,d   Müller, Frank Ulrich ^e,f   more..

^a UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^b German Atrial Fibrillation Competence NETwork ^*  (Germany)

^c Institute OfCardiometabolism and Nutrition   (France)

^d SORBONNE UNIVERSITÉ   (France)

^e BAYLOR COLLEGE OF MEDICINE   (United States)

^f UNIVERSITY OF MÜNSTER   (Germany)

^g MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

Atrial fibrillation; cAMP dependent gene regulation; Substrate remodelling; Transgenic mice

Indexed keywords

ALPHA ACTININ; CALCIUM; CONNEXIN 40; CONNEXIN 43; CYCLIC AMP RESPONSIVE ELEMENT MODULATOR;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM HOMEOSTASIS; CELL ELONGATION; CELL STIMULATION; CONTROLLED STUDY; DOWN REGULATION; GENE OVEREXPRESSION; GENETIC REGULATION; HEART ATRIUM CONDUCTION; HEART ATRIUM ENLARGEMENT; HEART ATRIUM FIBRILLATION; HEART DEPOLARIZATION; HEART MUSCLE CELL; HEART MUSCLE CONDUCTION DISTURBANCE; HEART MUSCLE FIBER MEMBRANE STEADY POTENTIAL; HEART MUSCLE FIBROSIS; HEART VENTRICLE HYPERTROPHY; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SARCOPLASMIC RETICULUM; TRANSGENIC MOUSE;

ANIMALS; ATRIAL FIBRILLATION; CYCLIC AMP RESPONSE ELEMENT MODULATOR; GENE EXPRESSION REGULATION; HEART ATRIA; MICE; MICE, TRANSGENIC; MYOCARDIUM; ORGAN CULTURE TECHNIQUES; TIME FACTORS;

EID: 84878014710     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2011.10.057     Document Type: Article

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