Functional recovery of human cells harbouring the mitochondrial DNA mutation MERRF A8344G via peptide-mediated mitochondrial delivery

NeuroSignals

Volumn 21, Issue 3-4, 2013, Pages 160-173

  Chang, Jui Chih ^a   Liu, Ko Hung ^a   Li, Yu Chi ^a   Kou, Shou Jen ^a   Wei, Yau Huei ^b,c   Chuang, Chieh Sen ^a   Hsieh, Mingli ^d   Liu, Chin San ^a  

^a CHANGHUA CHRISTIAN HOSPITAL   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c MACKAY MEDICAL COLLEGE   (Taiwan)

^d TUNGHAI UNIVERSITY   (Taiwan)

Author keywords

Cell penetrating peptide; Mitochondrial biogenesis; Mitochondrial delivery; Mitochondrial functions; Mitochondrial fusion fission proteins; Myoclonic epilepsy with ragged red fibres syndrome

Indexed keywords

CASPASE 3; CASPASE 7; CELL PENETRATING PEPTIDE; CELL PENETRATING PEPTIDE 1; DYNAMIN; DYNAMIN RELATED PROTEIN 1; FISSION 1 PROTEIN; MITOCHONDRIAL DNA; MITOCHONDRIAL TRANSCRIPTION FACTOR A; MITOFUSIN 2; NUCLEAR RESPIRATORY FACTOR 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; UNCLASSIFIED DRUG;

ARTICLE; CALCIUM TRANSPORT; CELL DEATH; CELL FUNCTION; CELL ISOLATION; CELL STRUCTURE; CELL SURVIVAL; CELL VIABILITY; CELL VIABILITY ASSAY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DNA EXTRACTION; DNA TRANSFER; DOWN REGULATION; ENZYME ACTIVITY; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GENE DOSAGE; GENE EXPRESSION; GENETIC TRANSFECTION; HOMEOSTASIS; HOST CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; INTERNALIZATION; MERRF SYNDROME; MITOCHONDRIAL DNA REPLICATION; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MITOCHONDRION SWELLING; OPTIC NERVE ATROPHY; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PEPTIDE MEDIATED MITOCHONDRIAL DELIVERY; POLYMERASE CHAIN REACTION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RNA EXTRACTION; SKIN FIBROBLAST; THREE DIMENSIONAL IMAGING; UPREGULATION; WESTERN BLOTTING;

EID: 84878014517     PISSN: 1424862X     EISSN: 14248638     Source Type: Journal    
DOI: 10.1159/000341981     Document Type: Article

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