Transient anabolic effects accompany epidermal growth factor receptor signal activation in articular cartilage in vivo

Arthritis Research and Therapy

Volumn 15, Issue 3, 2013, Pages

  Shepard, John B ^a   Jeong, Jae Wook ^b   Maihle, Nita J ^c   O'Brien, Sean ^a   Dealy, Caroline N ^a,d  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

^c YALE UNIVERSITY   (United States)

^d UNIVERSITY OF CONNECTICUT SCHOOL OF MEDICINE   (United States)

Author keywords

Articular cartilage; Cartilage repair; Chondroprogenitors; EGFR; Epidermal growth factor receptor; Mig 6; Osteoarthritis; Progenitor cells

Indexed keywords

AGGRECAN; BETA CATENIN; COLLAGEN; COLLAGEN TYPE 10; EPIDERMAL GROWTH FACTOR RECEPTOR; GROWTH DIFFERENTIATION FACTOR 5; NOTCH1 RECEPTOR; PREGNANCY ASSOCIATED ALPHA2 GLYCOPROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSCRIPTION FACTOR SOX9; TRANSFORMING GROWTH FACTOR BETA; EGFR PROTEIN, MOUSE; RALT PROTEIN, MOUSE; SIGNAL PEPTIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ARTICULAR CARTILAGE; BIOSYNTHESIS; CARTILAGE CELL; CATABOLISM; CELL POPULATION; CELL PROLIFERATION; CONTROLLED STUDY; DEGRADATION; HISTOPATHOLOGY; HYPERTROPHY; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MALE; MORPHOLOGY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; STAINING; STEM CELL; ANIMAL; IN SITU HYBRIDIZATION; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; CARTILAGE, ARTICULAR; CHONDROCYTES; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, KNOCKOUT; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION;

EID: 84878007459     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar4233     Document Type: Article

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