22-Oxacalcitriol prevents progression of endothelial dysfunction through antioxidative effects in rats with type 2 diabetes and early-stage nephropathy

Nephrology Dialysis Transplantation

Volumn 28, Issue 5, 2013, Pages 1166-1174

  Hirata, Michinori ^a   Serizawa, Ken Ichi ^a   Aizawa, Ken ^a   Yogo, Kenji ^a   Tashiro, Yoshihito ^a   Takeda, Satoshi ^a   Moriguchi, Yoshiyuki ^a   Endo, Koichi ^a   Fukagawa, Masafumi ^b  

^a CHUGAI PHARMACEUTICAL CO LTD   (Japan)

^b TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

22 oxacalcitriol; endothelial dysfunction; endothelial nitric oxide synthase; reactive oxygen species; type 2 diabetes

Indexed keywords

22 OXACALCITRIOL; DIMER; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUCOSE; MONOMER; PROTEIN P22; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD PRESSURE MEASUREMENT; CELL CULTURE; CONTROLLED STUDY; DISEASE COURSE; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; FEMORAL ARTERY; GLUCOSE BLOOD LEVEL; HYPERCALCEMIA; HYPERPHOSPHATEMIA; IN VIVO STUDY; KIDNEY DISEASE; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

22-OXACALCITRIOL; ENDOTHELIAL DYSFUNCTION; ENDOTHELIAL NITRIC OXIDE SYNTHASE; REACTIVE OXYGEN SPECIES; TYPE 2 DIABETES;

ANIMALS; ANTINEOPLASTIC AGENTS; BLOTTING, WESTERN; CALCITRIOL; CELLS, CULTURED; CORONARY VESSELS; DIABETES MELLITUS, TYPE 2; ENDOTHELIUM, VASCULAR; HUMANS; KIDNEY DISEASES; MALE; NADPH OXIDASE; NITRIC OXIDE SYNTHASE TYPE III; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; VASODILATION;

EID: 84877980088     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfs536     Document Type: Article

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