-
1
-
-
42449106768
-
Effects of chronic treatment with an oral growth hormone (GH) secretagogue on nocturnal GH and insulin-like growth factor-I (IGFI) in older men and women
-
Merriam GR, Blackman M, Hoffman A, Salvatori R, Wei JY, White HK, et al: Effects of chronic treatment with an oral growth hormone (GH) secretagogue on nocturnal GH and insulin-like growth factor-I (IGFI) in older men and women. Front Neuroendocrinol 2006; 27: 36-37.
-
(2006)
Front Neuroendocrinol
, vol.27
, pp. 36-37
-
-
Merriam, G.R.1
Blackman, M.2
Hoffman, A.3
Salvatori, R.4
Wei, J.Y.5
White, H.K.6
-
2
-
-
81755161554
-
Ghrelin as a target for gastrointestinal motility disorders
-
Greenwood-Van MB, Kriegsman M, Nelson R: Ghrelin as a target for gastrointestinal motility disorders. Peptides 2011; 32: 2352-2356.
-
(2011)
Peptides
, vol.32
, pp. 2352-2356
-
-
Greenwood-Van, M.B.1
Kriegsman, M.2
Nelson, R.3
-
3
-
-
7644219561
-
Feeding response to ghrelin agonist and antagonist in lean and obese Zucker rats
-
Beck B, Richy S, Stricker-Krongrad A: Feeding response to ghrelin agonist and antagonist in lean and obese Zucker rats. Life Sci 2004; 76: 473-478.
-
(2004)
Life Sci
, vol.76
, pp. 473-478
-
-
Beck, B.1
Richy, S.2
Stricker-Krongrad, A.3
-
4
-
-
80051570581
-
The Peptidic GHS-R antagonist [ D -Lys(3)]GHRP-6 markedly improves adiposity and related metabolic abnormalities in a mouse model of postmenopausal obesity
-
Maletinska L, Matyskova R, Maixnerova J, Sykora D, Pychova M, Spolcova A, et al: The Peptidic GHS-R antagonist [ D -Lys(3)]GHRP-6 markedly improves adiposity and related metabolic abnormalities in a mouse model of postmenopausal obesity. Mol Cell Endocrinol 2011; 343: 55-62.
-
(2011)
Mol Cell Endocrinol
, vol.343
, pp. 55-62
-
-
Maletinska, L.1
Matyskova, R.2
Maixnerova, J.3
Sykora, D.4
Pychova, M.5
Spolcova, A.6
-
5
-
-
35548949948
-
Small-molecule ghrelin receptor antagonists improve glucose tolerance, suppress appetite, and promote weight loss
-
Esler WP, Rudolph J, Claus TH, Tang W, Barucci N, Brown SE, et al: Small-molecule ghrelin receptor antagonists improve glucose tolerance, suppress appetite, and promote weight loss. Endocrinology 2007; 148: 5175-5185.
-
(2007)
Endocrinology
, vol.148
, pp. 5175-5185
-
-
Esler, W.P.1
Rudolph, J.2
Claus, T.H.3
Tang, W.4
Barucci, N.5
Brown, S.E.6
-
6
-
-
84891730724
-
Long term treatment with non-peptide ghrelin receptor ligands affects energy balance in mice fed a high-fat diet
-
Roy MC, Paradis E, Samson P, Thiboutot-Gagnon N, Marcotte M, Lachance Y, et al: Long term treatment with non-peptide ghrelin receptor ligands affects energy balance in mice fed a high-fat diet. ENDO 2007: 2-9.
-
(2007)
ENDO
, pp. 2-9
-
-
Roy, M.C.1
Paradis, E.2
Samson, P.3
Thiboutot-Gagnon, N.4
Marcotte, M.5
Lachance, Y.6
-
7
-
-
67650500621
-
Requirement of central ghrelin signaling for alcohol reward
-
Jerlhag E, Egecioglu E, Landgren S, Salome N, Heilig M, Moechars D, et al: Requirement of central ghrelin signaling for alcohol reward. Proc Natl Acad Sci USA 2009; 106: 11318-11323.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 11318-11323
-
-
Jerlhag, E.1
Egecioglu, E.2
Landgren, S.3
Salome, N.4
Heilig, M.5
Moechars, D.6
-
8
-
-
4644308857
-
Novel analogs of ghrelin: Physiological and clinical implications
-
Halem HA, Taylor JE, Dong JZ, Shen Y, Datta R, Abizaid A, et al: Novel analogs of ghrelin: physiological and clinical implications. Eur J Endocrinol 2004; 151(suppl 1):S71-S75.
-
(2004)
Eur J Endocrinol
, vol.151
, pp. S71-S75
-
-
Halem, H.A.1
Taylor, J.E.2
Dong, J.Z.3
Shen, Y.4
Datta, R.5
Abizaid, A.6
-
9
-
-
80053385649
-
GSK1614343, a novel ghrelin receptor antagonist, produces an unexpected increase of food intake and body weight in rodents and dogs
-
Costantini VJ, Vicentini E, Sabbatini FM, Valerio E, Lepore S, Tessari M, et al: GSK1614343, a novel ghrelin receptor antagonist, produces an unexpected increase of food intake and body weight in rodents and dogs. Neuroendocrinology 2011; 94: 158-168.
-
(2011)
Neuroendocrinology
, vol.94
, pp. 158-168
-
-
Costantini, V.J.1
Vicentini, E.2
Sabbatini, F.M.3
Valerio, E.4
Lepore, S.5
Tessari, M.6
-
10
-
-
0242330291
-
High constitutive signaling of the ghrelin receptor - Identification of a potent inverse agonist
-
Holst B, Cygankiewicz A, Jensen TH, Ankersen M, Schwartz TW: High constitutive signaling of the ghrelin receptor - identification of a potent inverse agonist. Mol Endocrinol 2003; 17: 2201-2210.
-
(2003)
Mol Endocrinol
, vol.17
, pp. 2201-2210
-
-
Holst, B.1
Cygankiewicz, A.2
Jensen, T.H.3
Ankersen, M.4
Schwartz, T.W.5
-
11
-
-
33646800511
-
Anti-ghrelin Spiegelmer NOX-B11 inhibits neurostimulatory and orexigenic effects of peripheral ghrelin in rats
-
Kobelt P, Helmling S, Stengel A, Wlotzka B, Andresen V, Klapp BF, et al: Anti-ghrelin Spiegelmer NOX-B11 inhibits neurostimulatory and orexigenic effects of peripheral ghrelin in rats. Gut 2006; 55: 788-792.
-
(2006)
Gut
, vol.55
, pp. 788-792
-
-
Kobelt, P.1
Helmling, S.2
Stengel, A.3
Wlotzka, B.4
Andresen, V.5
Klapp, B.F.6
-
12
-
-
32644448802
-
Ghrelin neutralization by a ribonucleic acid-SPM ameliorates obesity in diet-induced obese mice
-
Shearman LP, Wang SP, Helmling S, Stribling DS, Mazur P, Ge L, et al: Ghrelin neutralization by a ribonucleic acid-SPM ameliorates obesity in diet-induced obese mice. Endocrinology 2006; 147: 1517-1526.
-
(2006)
Endocrinology
, vol.147
, pp. 1517-1526
-
-
Shearman, L.P.1
Wang, S.P.2
Helmling, S.3
Stribling, D.S.4
Mazur, P.5
Ge, L.6
-
13
-
-
36949026161
-
The anti-ghrelin Spiegelmer NOXB11-3 blocks ghrelin- but not fasting-induced neuronal activation in the hypothalamic arcuate nucleus
-
Becskei C, Bilik KU, Klussmann S, Jarosch F, Lutz TA, Riediger T: The anti-ghrelin Spiegelmer NOXB11-3 blocks ghrelin- but not fasting-induced neuronal activation in the hypothalamic arcuate nucleus. J Neuroendocrinol 2008; 20: 85-92.
-
(2008)
J Neuroendocrinol
, vol.20
, pp. 85-92
-
-
Becskei, C.1
Bilik, K.U.2
Klussmann, S.3
Jarosch, F.4
Lutz, T.A.5
Riediger, T.6
-
14
-
-
63849244534
-
An acyl-ghrelin-specific neutralizing antibody inhibits the acute ghrelin-mediated orexigenic effects in mice
-
Lu SC, Xu J, Chinookoswong N, Liu S, Steavenson S, Gegg C, et al: An acyl-ghrelin-specific neutralizing antibody inhibits the acute ghrelin-mediated orexigenic effects in mice. Mol Pharmacol 2009; 75: 901-907.
-
(2009)
Mol Pharmacol
, vol.75
, pp. 901-907
-
-
Lu, S.C.1
Xu, J.2
Chinookoswong, N.3
Liu, S.4
Steavenson, S.5
Gegg, C.6
-
15
-
-
33748354456
-
Vaccination against weight gain
-
Zorrilla EP, Iwasaki S, Moss JA, Chang J, Otsuji J, Inoue K, et al: Vaccination against weight gain. Proc Natl Acad Sci USA 2006; 103: 13226-13231.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 13226-13231
-
-
Zorrilla, E.P.1
Iwasaki, S.2
Moss, J.A.3
Chang, J.4
Otsuji, J.5
Inoue, K.6
-
16
-
-
78650304822
-
Glucose and weight control in mice with a designed ghrelin O -acyltransferase inhibitor
-
Barnett BP, Hwang Y, Taylor MS, Kirchner H, Pfluger PT, Bernard V, et al: Glucose and weight control in mice with a designed ghrelin O -acyltransferase inhibitor. Science 2010; 330: 1689-1692.
-
(2010)
Science
, vol.330
, pp. 1689-1692
-
-
Barnett, B.P.1
Hwang, Y.2
Taylor, M.S.3
Kirchner, H.4
Pfluger, P.T.5
Bernard, V.6
-
17
-
-
33846435771
-
Acylated and unacylated ghrelin promote proliferation and inhibit apoptosis of pancreatic beta-cells and human islets: Involvement of 3 ' ,5 ' -cyclic adenosine monophosphate/protein kinase A, extracellular signal-regulated kinase 1/2, and phosphatidyl inositol 3-kinase/Akt signaling
-
Granata R, Settanni F, Biancone L, Trovato L, Nano R, Bertuzzi F, et al: Acylated and unacylated ghrelin promote proliferation and inhibit apoptosis of pancreatic beta-cells and human islets: involvement of 3 ' ,5 ' -cyclic adenosine monophosphate/protein kinase A, extracellular signal-regulated kinase 1/2, and phosphatidyl inositol 3-kinase/Akt signaling. Endocrinology 2007; 148: 512-529.
-
(2007)
Endocrinology
, vol.148
, pp. 512-529
-
-
Granata, R.1
Settanni, F.2
Biancone, L.3
Trovato, L.4
Nano, R.5
Bertuzzi, F.6
-
18
-
-
77954749961
-
Unacylated ghrelin and obestatin increase islet cell mass and prevent diabetes in streptozotocin-treated newborn rats
-
Granata R, Volante M, Settanni F, Gauna C, Ghe C, Annunziata M, et al: Unacylated ghrelin and obestatin increase islet cell mass and prevent diabetes in streptozotocin-treated newborn rats. J Mol Endocrinol 2010; 45: 9-17.
-
(2010)
J Mol Endocrinol
, vol.45
, pp. 9-17
-
-
Granata, R.1
Volante, M.2
Settanni, F.3
Gauna, C.4
Ghe, C.5
Annunziata, M.6
-
19
-
-
84858731418
-
Unacylated ghrelin fragments and analogues promote survival of pancreatic betacells and human pancreatic islets and prevent diabetes in streptozotocin-treated rats
-
Granata R, Settanni F, Julien M, Nano R, Togliatto G, Trombetta A, et al: Unacylated ghrelin fragments and analogues promote survival of pancreatic betacells and human pancreatic islets and prevent diabetes in streptozotocin-treated rats. J Med Chem 2012; 55: 2585-2596.
-
(2012)
J Med Chem
, vol.55
, pp. 2585-2596
-
-
Granata, R.1
Settanni, F.2
Julien, M.3
Nano, R.4
Togliatto, G.5
Trombetta, A.6
-
20
-
-
84875746147
-
Des-acyl ghrelin analogs prevent high-fat-dietinduced dysregulation of glucose homeostasis
-
in press
-
Delhanty PJ, Huisman M, Baldeon-Rojas LY, van den Berge I, Grefhorst A, Abribat T, Leenen PJ, Themmen AP, van der Lely AJ: Des-acyl ghrelin analogs prevent high-fat-dietinduced dysregulation of glucose homeostasis. FASEB J 2013;in press.
-
(2013)
FASEB J
-
-
Delhanty, P.J.1
Huisman, M.2
Baldeon-Rojas, L.Y.3
Van Den Berge, I.4
Grefhorst, A.5
Abribat, T.6
Leenen, P.J.7
Themmen, A.P.8
Van Der Lely, A.J.9
-
21
-
-
84866015238
-
In vitro and in vivo stability and pharmacokinetic profile of unacylated ghrelin (UAG) analogues
-
Julien M, Kay R, Delhanty P, Allas S, Granata R, Barton C, et al: In vitro and in vivo stability and pharmacokinetic profile of unacylated ghrelin (UAG) analogues. Eur J Pharm Sci 2012; 47: 625-635.
-
(2012)
Eur J Pharm Sci
, vol.47
, pp. 625-635
-
-
Julien, M.1
Kay, R.2
Delhanty, P.3
Allas, S.4
Granata, R.5
Barton, C.6
-
22
-
-
84891725608
-
Rapidly and strong suppression of human acylated ghrelin serum concentrations during infusion of des-acyl ghrelin in obese diabetic subjects
-
Özcan B, Neggers SJCMM, Miller AR, Yang H, Delhanty P, Allas S, et al: Rapidly and strong suppression of human acylated ghrelin serum concentrations during infusion of des-acyl ghrelin in obese diabetic subjects. Endocr Abstr 2012; 29: 711.
-
(2012)
Endocr Abstr
, vol.29
, pp. 711
-
-
Özcan, B.1
Neggers, S.J.C.M.M.2
Miller, A.R.3
Yang, H.4
Delhanty, P.5
Allas, S.6
-
23
-
-
77951156798
-
Unacylated ghrelin rescues endothelial progenitor cell function in individuals with type 2 diabetes
-
Togliatto G, Trombetta A, Dentelli P, Baragli A, Rosso A, Granata R, et al: Unacylated ghrelin rescues endothelial progenitor cell function in individuals with type 2 diabetes. Diabetes 2010; 59: 1016-1025.
-
(2010)
Diabetes
, vol.59
, pp. 1016-1025
-
-
Togliatto, G.1
Trombetta, A.2
Dentelli, P.3
Baragli, A.4
Rosso, A.5
Granata, R.6
-
24
-
-
0037164747
-
Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI 3-kinase/ AKT
-
Baldanzi G, Filigheddu N, Cutrupi S, Catapano F, Bonissoni S, Fubini A, et al: Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI 3-kinase/ AKT. J Cell Biol 2002; 159: 1029-1037.
-
(2002)
J Cell Biol
, vol.159
, pp. 1029-1037
-
-
Baldanzi, G.1
Filigheddu, N.2
Cutrupi, S.3
Catapano, F.4
Bonissoni, S.5
Fubini, A.6
-
25
-
-
77954599072
-
Desacyl ghrelin has specific binding sites and different metabolic effects from ghrelin in cardiomyocytes
-
Lear PV, Iglesias MJ, Feijoo-Bandin S, Rodriguez-Penas D, Mosquera-Leal A, Garcia-Rua V, et al: Desacyl ghrelin has specific binding sites and different metabolic effects from ghrelin in cardiomyocytes. Endocrinology 2010; 151: 3286-3298.
-
(2010)
Endocrinology
, vol.151
, pp. 3286-3298
-
-
Lear, P.V.1
Iglesias, M.J.2
Feijoo-Bandin, S.3
Rodriguez-Penas, D.4
Mosquera-Leal, A.5
Garcia-Rua, V.6
-
26
-
-
33947186298
-
Ghrelin and des-acyl ghrelin promote differentiation and fusion of C2C12 skeletal muscle cells
-
Filigheddu N, Gnocchi VF, Coscia M, Cappelli M, Porporato PE, Taulli R, et al: Ghrelin and des-acyl ghrelin promote differentiation and fusion of C2C12 skeletal muscle cells. Mol Biol Cell 2007; 18: 986-994.
-
(2007)
Mol Biol Cell
, vol.18
, pp. 986-994
-
-
Filigheddu, N.1
Gnocchi, V.F.2
Coscia, M.3
Cappelli, M.4
Porporato, P.E.5
Taulli, R.6
-
27
-
-
84857138764
-
Des-acyl ghrelin exhibits proanabolic and anti-catabolic effects on C2C12 myotubes exposed to cytokines and reduces burn-induced muscle proteolysis in rats
-
Sheriff S, Kadeer N, Joshi R, Friend LA, Howard JJ, Balasubramaniam A: Des-acyl ghrelin exhibits proanabolic and anti-catabolic effects on C2C12 myotubes exposed to cytokines and reduces burn-induced muscle proteolysis in rats. Mol Cell Endocrinol 2012; 351: 286-295.
-
(2012)
Mol Cell Endocrinol
, vol.351
, pp. 286-295
-
-
Sheriff, S.1
Kadeer, N.2
Joshi, R.3
Friend, L.A.4
Howard, J.J.5
Balasubramaniam, A.6
|