GSK1614343, a novel ghrelin receptor antagonist, produces an unexpected increase of food intake and body weight in rodents and dogs

Neuroendocrinology

Volumn 94, Issue 2, 2011, Pages 158-168

  Costantini, Vivian J A ^a,b   Vicentini, Elena ^a   Sabbatini, Fabio M ^a   Valerio, Enzo ^a   Lepore, Stefano ^a   Tessari, Michela ^a   Sartori, Matteo ^a   Michielin, Francesca ^a   Melotto, Sergio ^a   Merlo Pich, Emilio ^a   Corsi, Mauro ^a  

^a GSK   (Italy)

^b Aptuit Inc   (United States)

Author keywords

Body weight; Dogs; Food intake; Ghrelin receptor antagonist; Ghsr null mice; GSK1614343

Indexed keywords

APPETITE STIMULANT; GHRELIN; GHRELIN RECEPTOR; GROWTH HORMONE SECRETAGOGUE RECEPTOR; GSK 1614343; PROOPIOMELANOCORTIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY MASS; BODY WEIGHT; DOG; FEMALE; FOOD INTAKE; GROWTH HORMONE RELEASE; MALE; MUSCLE MASS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEOTIDE SEQUENCE; OBESITY; PRIORITY JOURNAL; RAT; RODENT; WEIGHT GAIN;

EID: 80053385649     PISSN: 00283835     EISSN: 14230194     Source Type: Journal    
DOI: 10.1159/000328968     Document Type: Article

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