The formation of oxytocin dimers is suppressed by the zinc-aspartate-oxytocin complex

Journal of Pharmaceutical Sciences

Volumn 102, Issue 6, 2013, Pages 1734-1741

  Avanti, Christina ^a,b   Hinrichs, Wouter L J ^b   Casini, Angela ^b   Eissens, Anko C ^b   Dam, Annie Van ^b   Kedrov, Alexej ^b   Driessen, Arnold J M ^b   Frijlink, Henderik W ^b   Permentier, Hjalmar P ^b  

^a UNIVERSITY OF SURABAYA   (Indonesia)

^b UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

Aqueous; Aspartate buffer; Degradation; Formulation; Kinetic; Oxytocin; Peptide; Stability; Zinc ions

Indexed keywords

ASPARTIC ACID; OXYTOCIN; ZINC;

ARTICLE; COMPLEX FORMATION; DRUG FORMULATION; DRUG STABILITY; GEL PERMEATION CHROMATOGRAPHY; ISOTHERMAL TITRATION CALORIMETRY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; TANDEM MASS SPECTROMETRY;

EID: 84877927966     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.23546     Document Type: Article

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