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Volumn 58, Issue 6, 2013, Pages 1157-1164

SUMOylated CPAP is required for IKK-mediated NF-κB activation and enhances HBx-induced NF-κB signaling in HCC

Author keywords

CPAP; HBx; HCC; IKK; NF kB; SUMOylation; TNF alpha

Indexed keywords

CENTROSOMAL PROTEIN P4.1 ASSOCIATED PROTEIN; HEPATITIS B VIRUS X PROTEIN; I KAPPA B KINASE; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; SMALL INTERFERING RNA; SUMO PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CENPJ PROTEIN, HUMAN; I KAPPA B; NF-KAPPAB INHIBITOR ALPHA; SUMO 1 PROTEIN; TRANSACTIVATOR PROTEIN;

EID: 84877927540     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2013.01.025     Document Type: Article
Times cited : (29)

References (27)
  • 1
    • 0034084163 scopus 로고    scopus 로고
    • Phosphorylation meets ubiquitination: The control of NF-[kappa]B activity
    • M. Karin, and Y. Ben-Neriah Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity Annu Rev Immunol 18 2000 621 663
    • (2000) Annu Rev Immunol , vol.18 , pp. 621-663
    • Karin, M.1    Ben-Neriah, Y.2
  • 2
    • 0029874138 scopus 로고    scopus 로고
    • The NF-kappa B and i kappa B proteins: New discoveries and insights
    • A.S. Baldwin Jr. The NF-kappa B and I kappa B proteins: new discoveries and insights Annu Rev Immunol 14 1996 649 683
    • (1996) Annu Rev Immunol , vol.14 , pp. 649-683
    • Baldwin, Jr.A.S.1
  • 3
    • 33750466230 scopus 로고    scopus 로고
    • Introduction to NF-kappaB: Players, pathways, perspectives
    • T.D. Gilmore Introduction to NF-kappaB: players, pathways, perspectives Oncogene 25 2006 6680 6684
    • (2006) Oncogene , vol.25 , pp. 6680-6684
    • Gilmore, T.D.1
  • 4
    • 2342522110 scopus 로고    scopus 로고
    • Shaping the nuclear action of NF-kappaB
    • L.F. Chen, and W.C. Greene Shaping the nuclear action of NF-kappaB Nat Rev Mol Cell Biol 5 2004 392 401
    • (2004) Nat Rev Mol Cell Biol , vol.5 , pp. 392-401
    • Chen, L.F.1    Greene, W.C.2
  • 5
    • 0036009115 scopus 로고    scopus 로고
    • NF-kappaB at the crossroads of life and death
    • M. Karin, and A. Lin NF-kappaB at the crossroads of life and death Nat Immunol 3 2002 221 227
    • (2002) Nat Immunol , vol.3 , pp. 221-227
    • Karin, M.1    Lin, A.2
  • 6
    • 0029982621 scopus 로고    scopus 로고
    • Hepatitis B virus HBx protein activates transcription factor NF-kappaB by acting on multiple cytoplasmic inhibitors of rel-related proteins
    • F. Su, and R.J. Schneider Hepatitis B virus HBx protein activates transcription factor NF-kappaB by acting on multiple cytoplasmic inhibitors of rel-related proteins J Virol 70 1996 4558 4566
    • (1996) J Virol , vol.70 , pp. 4558-4566
    • Su, F.1    Schneider, R.J.2
  • 7
    • 69549092821 scopus 로고    scopus 로고
    • Systematic-omics analysis of HBV-associated liver diseases
    • W. Sun, F. Zhong, L. Zhi, G. Zhou, and F. He Systematic-omics analysis of HBV-associated liver diseases Cancer Lett 286 2009 89 95
    • (2009) Cancer Lett , vol.286 , pp. 89-95
    • Sun, W.1    Zhong, F.2    Zhi, L.3    Zhou, G.4    He, F.5
  • 8
    • 54249125424 scopus 로고    scopus 로고
    • NF-kappaB signaling, liver disease and hepatoprotective agents
    • B. Sun, and M. Karin NF-kappaB signaling, liver disease and hepatoprotective agents Oncogene 27 2008 6228 6244
    • (2008) Oncogene , vol.27 , pp. 6228-6244
    • Sun, B.1    Karin, M.2
  • 9
    • 0037421484 scopus 로고    scopus 로고
    • NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia
    • M. Dajee, M. Lazarov, J.Y. Zhang, T. Cai, C.L. Green, and A.J. Russell NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia Nature 421 2003 639 643
    • (2003) Nature , vol.421 , pp. 639-643
    • Dajee, M.1    Lazarov, M.2    Zhang, J.Y.3    Cai, T.4    Green, C.L.5    Russell, A.J.6
  • 10
    • 21244472975 scopus 로고    scopus 로고
    • IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis
    • S. Maeda, H. Kamata, J.L. Luo, H. Leffert, and M. Karin IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis Cell 121 2005 977 990
    • (2005) Cell , vol.121 , pp. 977-990
    • Maeda, S.1    Kamata, H.2    Luo, J.L.3    Leffert, H.4    Karin, M.5
  • 11
    • 0346505340 scopus 로고    scopus 로고
    • The IKK NF-kappa B system: A treasure trove for drug development
    • M. Karin, Y. Yamamoto, and Q.M. Wang The IKK NF-kappa B system: a treasure trove for drug development Nat Rev Drug Discov 3 2004 17 26
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 17-26
    • Karin, M.1    Yamamoto, Y.2    Wang, Q.M.3
  • 12
    • 16844366650 scopus 로고    scopus 로고
    • Nuclear factor-kappaB inhibitors as sensitizers to anticancer drugs
    • C. Nakanishi, and M. Toi Nuclear factor-kappaB inhibitors as sensitizers to anticancer drugs Nat Rev Cancer 5 2005 297 309
    • (2005) Nat Rev Cancer , vol.5 , pp. 297-309
    • Nakanishi, C.1    Toi, M.2
  • 13
    • 16844382708 scopus 로고    scopus 로고
    • Centrosomal P4.1-associated protein is a new member of transcriptional coactivators for nuclear factor-kappaB
    • M. Koyanagi, M. Hijikata, K. Watashi, O. Masui, and K. Shimotohno Centrosomal P4.1-associated protein is a new member of transcriptional coactivators for nuclear factor-kappaB J Biol Chem 280 2005 12430 12437
    • (2005) J Biol Chem , vol.280 , pp. 12430-12437
    • Koyanagi, M.1    Hijikata, M.2    Watashi, K.3    Masui, O.4    Shimotohno, K.5
  • 14
    • 48849104246 scopus 로고    scopus 로고
    • Functional characterization of the microtubule-binding and -destabilizing domains of CPAP and d-SAS-4
    • W.B. Hsu, L.Y. Hung, C.J. Tang, C.L. Su, Y. Chang, and T.K. Tang Functional characterization of the microtubule-binding and -destabilizing domains of CPAP and d-SAS-4 Exp Cell Res 314 2008 2591 2602
    • (2008) Exp Cell Res , vol.314 , pp. 2591-2602
    • Hsu, W.B.1    Hung, L.Y.2    Tang, C.J.3    Su, C.L.4    Chang, Y.5    Tang, T.K.6
  • 15
    • 2542483497 scopus 로고    scopus 로고
    • Identification of a novel microtubule-destabilizing motif in CPAP that binds to tubulin heterodimers and inhibits microtubule assembly
    • L.Y. Hung, H.L. Chen, C.W. Chang, B.R. Li, and T.K. Tang Identification of a novel microtubule-destabilizing motif in CPAP that binds to tubulin heterodimers and inhibits microtubule assembly Mol Biol Cell 15 2004 2697 2706
    • (2004) Mol Biol Cell , vol.15 , pp. 2697-2706
    • Hung, L.Y.1    Chen, H.L.2    Chang, C.W.3    Li, B.R.4    Tang, T.K.5
  • 16
    • 0033800738 scopus 로고    scopus 로고
    • Protein 4.1 R-135 interacts with a novel centrosomal protein (CPAP) which is associated with the gamma-tubulin complex
    • L.Y. Hung, C.J. Tang, and T.K. Tang Protein 4.1 R-135 interacts with a novel centrosomal protein (CPAP) which is associated with the gamma-tubulin complex Mol Cell Biol 20 2000 7813 7825
    • (2000) Mol Cell Biol , vol.20 , pp. 7813-7825
    • Hung, L.Y.1    Tang, C.J.2    Tang, T.K.3
  • 17
    • 4444301185 scopus 로고    scopus 로고
    • SUMO and ubiquitin in the nucleus: Different functions, similar mechanisms?
    • G. Gill SUMO and ubiquitin in the nucleus: different functions, similar mechanisms? Genes Dev 18 2004 2046 2059
    • (2004) Genes Dev , vol.18 , pp. 2046-2059
    • Gill, G.1
  • 18
    • 0036300965 scopus 로고    scopus 로고
    • Ubiquitin-related modifier SUMO1 and nucleocytoplasmic transport
    • A. Pichler, and F. Melchior Ubiquitin-related modifier SUMO1 and nucleocytoplasmic transport Traffic 3 2002 381 387
    • (2002) Traffic , vol.3 , pp. 381-387
    • Pichler, A.1    Melchior, F.2
  • 19
    • 0037295721 scopus 로고    scopus 로고
    • Modification with SUMO. A role in transcriptional regulation
    • A. Verger, J. Perdomo, and M. Crossley Modification with SUMO. A role in transcriptional regulation EMBO Rep 4 2003 137 142
    • (2003) EMBO Rep , vol.4 , pp. 137-142
    • Verger, A.1    Perdomo, J.2    Crossley, M.3
  • 20
    • 3042712867 scopus 로고    scopus 로고
    • Overproduction of eukaryotic SUMO-1- and SUMO-2-conjugated proteins in Escherichia coli
    • Y. Uchimura, M. Nakamura, K. Sugasawa, M. Nakao, and H. Saitoh Overproduction of eukaryotic SUMO-1- and SUMO-2-conjugated proteins in Escherichia coli Anal Biochem 331 2004 204 206
    • (2004) Anal Biochem , vol.331 , pp. 204-206
    • Uchimura, Y.1    Nakamura, M.2    Sugasawa, K.3    Nakao, M.4    Saitoh, H.5
  • 21
    • 1842850624 scopus 로고    scopus 로고
    • Generation of SUMO-1 modified proteins in E. coli: Towards understanding the biochemistry/structural biology of the SUMO-1 pathway
    • Y. Uchimura, M. Nakao, and H. Saitoh Generation of SUMO-1 modified proteins in E. coli: towards understanding the biochemistry/structural biology of the SUMO-1 pathway FEBS Lett 564 2004 85 90
    • (2004) FEBS Lett , vol.564 , pp. 85-90
    • Uchimura, Y.1    Nakao, M.2    Saitoh, H.3
  • 22
    • 33745298519 scopus 로고    scopus 로고
    • Nuclear factor-kappaB in cancer development and progression
    • M. Karin Nuclear factor-kappaB in cancer development and progression Nature 441 2006 431 436
    • (2006) Nature , vol.441 , pp. 431-436
    • Karin, M.1
  • 23
    • 4644324186 scopus 로고    scopus 로고
    • NF-kappaB functions as a tumour promoter in inflammation-associated cancer
    • E. Pikarsky, R.M. Porat, I. Stein, R. Abramovitch, S. Amit, and S. Kasem NF-kappaB functions as a tumour promoter in inflammation-associated cancer Nature 431 2004 461 466
    • (2004) Nature , vol.431 , pp. 461-466
    • Pikarsky, E.1    Porat, R.M.2    Stein, I.3    Abramovitch, R.4    Amit, S.5    Kasem, S.6
  • 24
    • 1142299661 scopus 로고    scopus 로고
    • Activating mechanism of transcriptor NF-kappaB regulated by hepatitis B virus X protein in hepatocellular carcinoma
    • T. Wang, Y. Wang, M.C. Wu, X.Y. Guan, and Z.F. Yin Activating mechanism of transcriptor NF-kappaB regulated by hepatitis B virus X protein in hepatocellular carcinoma World J Gastroenterol 10 2004 356 360
    • (2004) World J Gastroenterol , vol.10 , pp. 356-360
    • Wang, T.1    Wang, Y.2    Wu, M.C.3    Guan, X.Y.4    Yin, Z.F.5
  • 26
    • 0034954277 scopus 로고    scopus 로고
    • X protein of hepatitis B virus modulates cytokine and growth factor related signal transduction pathways during the course of viral infections and hepatocarcinogenesis
    • J. Diao, R. Garces, and C.D. Richardson X protein of hepatitis B virus modulates cytokine and growth factor related signal transduction pathways during the course of viral infections and hepatocarcinogenesis Cytokine Growth Factor Rev 12 2001 189 205
    • (2001) Cytokine Growth Factor Rev , vol.12 , pp. 189-205
    • Diao, J.1    Garces, R.2    Richardson, C.D.3
  • 27
    • 33750432183 scopus 로고    scopus 로고
    • Nuclear factor-kappaB and inhibitor of kappaB kinase pathways in oncogenic initiation and progression
    • D.S. Basseres, and A.S. Baldwin Nuclear factor-kappaB and inhibitor of kappaB kinase pathways in oncogenic initiation and progression Oncogene 25 2006 6817 6830
    • (2006) Oncogene , vol.25 , pp. 6817-6830
    • Basseres, D.S.1    Baldwin, A.S.2


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