Structure reveals function of the dual variable domain immunoglobulin (DVD-Ig™) molecule

mAbs

Volumn 5, Issue 3, 2013, Pages 358-363

  Jakob, Clarissa G ^a   Edalji, Rohinton ^a   Judge, Russell A ^a   DiGiammarino, Enrico ^a   Li, Yingchun ^a   Gu, Jijie ^a   Ghayur, Tariq ^a  

^a ABBVIE INC   (United States)

Author keywords

DFab; Dual Specific Antibody; IL12; IL18

Indexed keywords

IMMUNOGLOBULIN; INTERLEUKIN 12; INTERLEUKIN 18; ANTIGEN; BISPECIFIC ANTIBODY; IMMUNOGLOBULIN VARIABLE REGION; MONOCLONAL ANTIBODY; PROTEIN BINDING;

ANTIBODY COMBINING SITE; ARTICLE; BINDING AFFINITY; CRYSTAL STRUCTURE; CRYSTALLIZATION; HEAVY CHAIN; HYDROGEN BOND; IMMUNOASSAY; IMMUNOGLOBULIN STRUCTURE; IMMUNOGLOBULIN VARIABLE REGION; LIGHT CHAIN; PROTEIN PURIFICATION; X RAY; ANTIBODY SPECIFICITY; CHEMISTRY; DRUG DESIGN; HUMAN; IMMUNOLOGY; IMMUNOTHERAPY; PROCEDURES; PROTEIN ENGINEERING; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

ANTIBODIES, BISPECIFIC; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; ANTIGENS; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; HUMANS; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOTHERAPY; INTERLEUKIN-12; INTERLEUKIN-18; PROTEIN BINDING; PROTEIN ENGINEERING; PROTEIN STRUCTURE, TERTIARY;

EID: 84877887262     PISSN: 19420862     EISSN: 19420870     Source Type: Journal    
DOI: 10.4161/mabs.23977     Document Type: Article

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