-
1
-
-
84856794168
-
Primary and Secondary Prevention of Cardiovascular Disease: Antithrombotic Therapy and Prevention of Thrombosis, American College of Chest Physicians. Evidence-Based Clinical Practice Guidelines 9thed
-
Vandvik PO, Lincoff AM, Gore JM, Gutterman DD, Sonnenberg FA, et al. (2012) Primary and Secondary Prevention of Cardiovascular Disease: Antithrombotic Therapy and Prevention of Thrombosis, American College of Chest Physicians. Evidence-Based Clinical Practice Guidelines 9thed. Chest 141: e637S-68S.
-
(2012)
Chest
, vol.141
-
-
Vandvik, P.O.1
Lincoff, A.M.2
Gore, J.M.3
Gutterman, D.D.4
Sonnenberg, F.A.5
-
2
-
-
59649117935
-
The largest prospective warfarin-treated cohort supports genetic forecasting
-
Wadelius M, Chen LY, Lindh JD, Eriksson N, Ghori MJ, et al. (2009) The largest prospective warfarin-treated cohort supports genetic forecasting. Blood 113: 784-792.
-
(2009)
Blood
, vol.113
, pp. 784-792
-
-
Wadelius, M.1
Chen, L.Y.2
Lindh, J.D.3
Eriksson, N.4
Ghori, M.J.5
-
3
-
-
47949086046
-
Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin
-
Gage BF, Eby C, Johnson JA, Deych E, Rieder MJ, et al. (2008) Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin. Clin Pharmacol Ther 84: 326-331.
-
(2008)
Clin Pharmacol Ther
, vol.84
, pp. 326-331
-
-
Gage, B.F.1
Eby, C.2
Johnson, J.A.3
Deych, E.4
Rieder, M.J.5
-
4
-
-
63449117825
-
A Genome-Wide Association Study Confirms VKORC1, CYP2C9, and CYP4F2 as Principal Genetic Determinants of Warfarin Dose
-
Takeuchi F, McGinnis R, Bourgeois S, Barnes C, Eriksson N, et al. (2009) A Genome-Wide Association Study Confirms VKORC1, CYP2C9, and CYP4F2 as Principal Genetic Determinants of Warfarin Dose. PLoS Genet 5: e1000433.
-
(2009)
PLoS Genet
, vol.5
-
-
Takeuchi, F.1
McGinnis, R.2
Bourgeois, S.3
Barnes, C.4
Eriksson, N.5
-
5
-
-
70350754462
-
A genome-wide association study of acenocoumarol maintenance dosage
-
Teichert M, Eijgelsheim M, Rivadeneira F, Uitterlinden AG, van Schaik RH, et al. (2009) A genome-wide association study of acenocoumarol maintenance dosage. Hum Mol Genet 18: 3758-3768.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 3758-3768
-
-
Teichert, M.1
Eijgelsheim, M.2
Rivadeneira, F.3
Uitterlinden, A.G.4
van Schaik, R.H.5
-
6
-
-
77949756362
-
Genome-wide association studies in pharmacogenomics
-
Daly AK, (2010) Genome-wide association studies in pharmacogenomics. Nat Rev Genet 11: 241-6.
-
(2010)
Nat Rev Genet
, vol.11
, pp. 241-246
-
-
Daly, A.K.1
-
7
-
-
60849097257
-
Estimation of the warfarin dose with clinical and pharmacogenetic data
-
International Warfarin Pharmacogenetics Consortium
-
International Warfarin Pharmacogenetics Consortium, Klein TE, Altman RB, Eriksson N, Gage BF, et al. (2009) Estimation of the warfarin dose with clinical and pharmacogenetic data. N Engl J Med 360: 753-764.
-
(2009)
N Engl J Med
, vol.360
, pp. 753-764
-
-
Klein, T.E.1
Altman, R.B.2
Eriksson, N.3
Gage, B.F.4
-
8
-
-
79251511257
-
Genetic warfarin dosing: tables versus algorithms
-
Finkelman BS, Gage BF, Johnson JA, Brensinger CM, Kimmel SE, (2011) Genetic warfarin dosing: tables versus algorithms. J Am Coll Cardiol 57: 612-618.
-
(2011)
J Am Coll Cardiol
, vol.57
, pp. 612-618
-
-
Finkelman, B.S.1
Gage, B.F.2
Johnson, J.A.3
Brensinger, C.M.4
Kimmel, S.E.5
-
9
-
-
73649109224
-
10 years of oral anticoagulant pharmacogenomics: what difference will it make? A critical appraisal
-
Kurnik D, Loebstein R, Halkin H, Gak E, Almog S, (2009) 10 years of oral anticoagulant pharmacogenomics: what difference will it make? A critical appraisal. Pharmacogenomics 10: 1955-1965.
-
(2009)
Pharmacogenomics
, vol.10
, pp. 1955-1965
-
-
Kurnik, D.1
Loebstein, R.2
Halkin, H.3
Gak, E.4
Almog, S.5
-
10
-
-
78650447994
-
Practical recommendations for pharmacogenomics-based prescription: 2010 ESF-UB Conference on Pharmacogenetics and Pharmacogenomics
-
Becquemont L, Alfirevic A, Amstutz U, Brauch H, Jacqz-Aigrain E, et al. (2011) Practical recommendations for pharmacogenomics-based prescription: 2010 ESF-UB Conference on Pharmacogenetics and Pharmacogenomics. Pharmacogenomics 12: 113-124.
-
(2011)
Pharmacogenomics
, vol.12
, pp. 113-124
-
-
Becquemont, L.1
Alfirevic, A.2
Amstutz, U.3
Brauch, H.4
Jacqz-Aigrain, E.5
-
11
-
-
52449132783
-
-
U.S. Food and Drug Administration, Rockville, MD: FDA. Available:. Accessed 2008 May 19
-
U.S. Food and Drug Administration (2007) Press Release: FDA approves updated warfarin (Coumadin) prescribing information. Rockville, MD: FDA. Available: http://www.fda.gov/bbs/topics/NEWS/2007/NEW01684.html. Accessed 2008 May 19.
-
(2007)
Press Release: FDA approves updated warfarin (Coumadin) prescribing information
-
-
-
12
-
-
84856772158
-
Evidence-based management of anticoagulant therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
-
Holbrook A, Schulman S, Witt DM, Vandvik PO, Fish J, et al. (2012) Evidence-based management of anticoagulant therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 141: e152S-84S.
-
(2012)
Chest
, vol.141
-
-
Holbrook, A.1
Schulman, S.2
Witt, D.M.3
Vandvik, P.O.4
Fish, J.5
-
13
-
-
70450133979
-
Implications of pharmacogenetics for oral anticoagulants metabolism
-
Pérez-Andreu V, Roldán V, González-Conejero R, Hernández-Romero D, Vicente V, et al. (2009) Implications of pharmacogenetics for oral anticoagulants metabolism. Curr Drug Metab 10: 632-642.
-
(2009)
Curr Drug Metab
, vol.10
, pp. 632-642
-
-
Pérez-Andreu, V.1
Roldán, V.2
González-Conejero, R.3
Hernández-Romero, D.4
Vicente, V.5
-
14
-
-
66549110050
-
Pharmacogenetic relevance of CYP4F2 V433M polymorphism on acenocoumarol therapy
-
Pérez-Andreu V, Roldán V, Antón AI, García-Barberá N, Corral J, et al. (2009) Pharmacogenetic relevance of CYP4F2 V433M polymorphism on acenocoumarol therapy. Blood 113: 4977-4979.
-
(2009)
Blood
, vol.113
, pp. 4977-4979
-
-
Pérez-Andreu, V.1
Roldán, V.2
Antón, A.I.3
García-Barberá, N.4
Corral, J.5
-
15
-
-
80051512500
-
EU-PACT Study Group Loading and maintenance dose algorithms for phenprocoumon and acenocoumarol using patient characteristics and pharmacogenetic data
-
van Schie RM, Wessels JA, le Cessie S, de Boer A, Schalekamp T, et al. (2011) EU-PACT Study Group Loading and maintenance dose algorithms for phenprocoumon and acenocoumarol using patient characteristics and pharmacogenetic data. Eur Heart J 32: 1909-1917.
-
(2011)
Eur Heart J
, vol.32
, pp. 1909-1917
-
-
van Schie, R.M.1
Wessels, J.A.2
le Cessie, S.3
de Boer, A.4
Schalekamp, T.5
-
16
-
-
77955293789
-
A novel, single algorithm approach to predict acenocoumarol dose based on CYP2C9 and VKORC1 allele variants
-
Verde Z, Ruiz JR, Santiago C, Valle B, Bandrés F, et al. (2010) A novel, single algorithm approach to predict acenocoumarol dose based on CYP2C9 and VKORC1 allele variants. PLoS One 5: e11210.
-
(2010)
PLoS One
, vol.5
-
-
Verde, Z.1
Ruiz, J.R.2
Santiago, C.3
Valle, B.4
Bandrés, F.5
-
17
-
-
33947231296
-
A coding VKORC1 Asp36Tyr polymorphism predisposes to warfarin resistance
-
Loebstein R, Dvoskin I, Halkin H, Vecsler M, Lubetsky A, et al. (2007) A coding VKORC1 Asp36Tyr polymorphism predisposes to warfarin resistance. Blood 109: 2477-2480.
-
(2007)
Blood
, vol.109
, pp. 2477-2480
-
-
Loebstein, R.1
Dvoskin, I.2
Halkin, H.3
Vecsler, M.4
Lubetsky, A.5
-
18
-
-
78650962974
-
Thirteen novel VKORC1 mutations associated with oral anticoagulant resistance: insights into improved patient diagnosis and treatment
-
Watzka M, Geisen C, Bevans CG, Sittinger K, Spohn G, et al. (2011) Thirteen novel VKORC1 mutations associated with oral anticoagulant resistance: insights into improved patient diagnosis and treatment. J Thromb Haemost 9: 109-118.
-
(2011)
J Thromb Haemost
, vol.9
, pp. 109-118
-
-
Watzka, M.1
Geisen, C.2
Bevans, C.G.3
Sittinger, K.4
Spohn, G.5
-
19
-
-
52449098058
-
Pharmacodynamic resistance to warfarin is associated with nucleotide substitutions in VKORC1
-
Harrington DJ, Gorska R, Wheeler R, Davidson S, Murden S, et al. (2008) Pharmacodynamic resistance to warfarin is associated with nucleotide substitutions in VKORC1. J Thromb Haemost 6: 1663-1670.
-
(2008)
J Thromb Haemost
, vol.6
, pp. 1663-1670
-
-
Harrington, D.J.1
Gorska, R.2
Wheeler, R.3
Davidson, S.4
Murden, S.5
-
20
-
-
55449100859
-
VKORC1 polymorphisms, haplotypes and haplotype groups on warfarin dose among African-Americans and European-Americans
-
Limdi NA, Beasley TM, Crowley MR, Goldstein JA, Rieder MJ, et al. (2008) VKORC1 polymorphisms, haplotypes and haplotype groups on warfarin dose among African-Americans and European-Americans. Pharmacogenomics 9: 1445-1458.
-
(2008)
Pharmacogenomics
, vol.9
, pp. 1445-1458
-
-
Limdi, N.A.1
Beasley, T.M.2
Crowley, M.R.3
Goldstein, J.A.4
Rieder, M.J.5
-
21
-
-
51649084617
-
Regulatory polymorphism in vitamin K epoxide reductase complex subunit 1 (VKORC1) affects gene expression and warfarin dose requirement
-
Wang D, Chen H, Momary KM, Cavallari LH, Johnson JA, et al. (2008) Regulatory polymorphism in vitamin K epoxide reductase complex subunit 1 (VKORC1) affects gene expression and warfarin dose requirement. Blood 112: 1013-1021.
-
(2008)
Blood
, vol.112
, pp. 1013-1021
-
-
Wang, D.1
Chen, H.2
Momary, K.M.3
Cavallari, L.H.4
Johnson, J.A.5
-
22
-
-
80052962391
-
Guidelines for CYP2C9 and VKORC1 genotypes and warfarin dosing
-
Johnson JA, Gong L, Whirl-Carrillo M, Gage BF, Scott SA, et al. (2011) Guidelines for CYP2C9 and VKORC1 genotypes and warfarin dosing. Clin Pharmacol Ther 90: 625-629.
-
(2011)
Clin Pharmacol Ther
, vol.90
, pp. 625-629
-
-
Johnson, J.A.1
Gong, L.2
Whirl-Carrillo, M.3
Gage, B.F.4
Scott, S.A.5
-
23
-
-
43549104967
-
VKORC1 Asp36Tyr warfarin resistance marker is common in Ethiopian individuals
-
Aklillu E, Leong C, Loebstein R, Halkin H, Gak E, (2008) VKORC1 Asp36Tyr warfarin resistance marker is common in Ethiopian individuals. Blood 111: 3903-3904.
-
(2008)
Blood
, vol.111
, pp. 3903-3904
-
-
Aklillu, E.1
Leong, C.2
Loebstein, R.3
Halkin, H.4
Gak, E.5
-
24
-
-
40749123052
-
Warfarin pharmacogenetics: CYP2C9 and VKORC1 genotypes predict different sensitivity and resistance frequencies in the Ashkenazi and Sephardi Jewish populations
-
Scott SA, Edelmann L, Kornreich R, Desnick RJ, (2008) Warfarin pharmacogenetics: CYP2C9 and VKORC1 genotypes predict different sensitivity and resistance frequencies in the Ashkenazi and Sephardi Jewish populations. Am J Hum Genet 82: 495-500.
-
(2008)
Am J Hum Genet
, vol.82
, pp. 495-500
-
-
Scott, S.A.1
Edelmann, L.2
Kornreich, R.3
Desnick, R.J.4
-
25
-
-
84858382877
-
Evaluation of the warfarin-resistance polymorphism, VKORC1 Asp36Tyr, and its effect on dosage algorithms in a genetically heterogeneous anticoagulant clinic
-
Shuen AY, Wong BY, Fu L, Selby R, Cole DE, (2012) Evaluation of the warfarin-resistance polymorphism, VKORC1 Asp36Tyr, and its effect on dosage algorithms in a genetically heterogeneous anticoagulant clinic. Clin Biochem 45: 397-401.
-
(2012)
Clin Biochem
, vol.45
, pp. 397-401
-
-
Shuen, A.Y.1
Wong, B.Y.2
Fu, L.3
Selby, R.4
Cole, D.E.5
-
26
-
-
47649112371
-
Multiple genetic alterations in vitamin K epoxide reductase complex subunit 1 gene (VKORC1) can explain the high dose requirement during oral anticoagulation in humans
-
Bodin L, Perdu J, Diry M, Horellou MH, Loriot MA, (2008) Multiple genetic alterations in vitamin K epoxide reductase complex subunit 1 gene (VKORC1) can explain the high dose requirement during oral anticoagulation in humans. J Thromb Haemost 6: 1436-1439.
-
(2008)
J Thromb Haemost
, vol.6
, pp. 1436-1439
-
-
Bodin, L.1
Perdu, J.2
Diry, M.3
Horellou, M.H.4
Loriot, M.A.5
-
27
-
-
61449103718
-
Novel mutations in the VKORC1 gene of wild rats and mice--a response to 50 years of selection pressure by warfarin?
-
Rost S, Pelz HJ, Menzel S, MacNicoll AD, León V, et al. (2009) Novel mutations in the VKORC1 gene of wild rats and mice--a response to 50 years of selection pressure by warfarin? BMC Genet 10: 4-12.
-
(2009)
BMC Genet
, vol.10
, pp. 4-12
-
-
Rost, S.1
Pelz, H.J.2
Menzel, S.3
MacNicoll, A.D.4
León, V.5
-
28
-
-
11244332058
-
A polymorphism in the VKORC1 gene is associated with an interindividual variability in the dose-anticoagulant effect of warfarin
-
D'Andrea G, D'Ambrosio RL, Di Perna P, Chetta M, Santacroce R, et al. (2005) A polymorphism in the VKORC1 gene is associated with an interindividual variability in the dose-anticoagulant effect of warfarin. Blood 105: 645-649.
-
(2005)
Blood
, vol.105
, pp. 645-649
-
-
D'Andrea, G.1
D'Ambrosio, R.L.2
Di Perna, P.3
Chetta, M.4
Santacroce, R.5
-
29
-
-
79960777339
-
Novel CYP2C9 and VKORC1 gene variants associated with warfarin dosage variability in the South African black population
-
Mitchell C, Gregersen N, Krause A, (2011) Novel CYP2C9 and VKORC1 gene variants associated with warfarin dosage variability in the South African black population. Pharmacogenomics 12: 953-963.
-
(2011)
Pharmacogenomics
, vol.12
, pp. 953-963
-
-
Mitchell, C.1
Gregersen, N.2
Krause, A.3
-
30
-
-
80052964856
-
Understanding the contribution of synonymous mutations to human disease
-
Sauna ZE, Kimchi-Sarfaty C, (2011) Understanding the contribution of synonymous mutations to human disease. Nat Rev Genet 12: 683-691.
-
(2011)
Nat Rev Genet
, vol.12
, pp. 683-691
-
-
Sauna, Z.E.1
Kimchi-Sarfaty, C.2
-
31
-
-
77958129007
-
Gamma-glutamyl carboxylase and its influence on warfarin dose
-
King CR, Deych E, Milligan P, Eby C, Lenzini P, et al. (2010) Gamma-glutamyl carboxylase and its influence on warfarin dose. Thromb Haemost 104: 750-754.
-
(2010)
Thromb Haemost
, vol.104
, pp. 750-754
-
-
King, C.R.1
Deych, E.2
Milligan, P.3
Eby, C.4
Lenzini, P.5
-
32
-
-
34447636585
-
The genetic interaction between VKORC1 c1173t and calumenin a29809g modulates the anticoagulant response of acenocoumarol
-
González-Conejero R, Corral J, Roldán V, Ferrer F, Sánchez-Serrano I, et al. (2007) The genetic interaction between VKORC1 c1173t and calumenin a29809g modulates the anticoagulant response of acenocoumarol. J Thromb Haemost 5: 1701-1706.
-
(2007)
J Thromb Haemost
, vol.5
, pp. 1701-1706
-
-
González-Conejero, R.1
Corral, J.2
Roldán, V.3
Ferrer, F.4
Sánchez-Serrano, I.5
-
33
-
-
84864609288
-
Copy number variation detection and genotyping from exome sequence data
-
Krumm N, Sudmant PH, Ko A, O'Roak BJ, Malig M, et al. (2012) Copy number variation detection and genotyping from exome sequence data. Genome Res 22: 1525-1532.
-
(2012)
Genome Res
, vol.22
, pp. 1525-1532
-
-
Krumm, N.1
Sudmant, P.H.2
Ko, A.3
O'Roak, B.J.4
Malig, M.5
|