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Volumn 8, Issue 5, 2013, Pages

Novel Associations of VKORC1 Variants with Higher Acenocoumarol Requirements

Author keywords

[No Author keywords available]

Indexed keywords

ACENOCOUMAROL; ANTICOAGULANT AGENT; VITAMIN K EPOXIDE REDUCTASE; VKORC1 PROTEIN, HUMAN;

EID: 84877872515     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0064469     Document Type: Article
Times cited : (16)

References (33)
  • 1
    • 84856794168 scopus 로고    scopus 로고
    • Primary and Secondary Prevention of Cardiovascular Disease: Antithrombotic Therapy and Prevention of Thrombosis, American College of Chest Physicians. Evidence-Based Clinical Practice Guidelines 9thed
    • Vandvik PO, Lincoff AM, Gore JM, Gutterman DD, Sonnenberg FA, et al. (2012) Primary and Secondary Prevention of Cardiovascular Disease: Antithrombotic Therapy and Prevention of Thrombosis, American College of Chest Physicians. Evidence-Based Clinical Practice Guidelines 9thed. Chest 141: e637S-68S.
    • (2012) Chest , vol.141
    • Vandvik, P.O.1    Lincoff, A.M.2    Gore, J.M.3    Gutterman, D.D.4    Sonnenberg, F.A.5
  • 2
    • 59649117935 scopus 로고    scopus 로고
    • The largest prospective warfarin-treated cohort supports genetic forecasting
    • Wadelius M, Chen LY, Lindh JD, Eriksson N, Ghori MJ, et al. (2009) The largest prospective warfarin-treated cohort supports genetic forecasting. Blood 113: 784-792.
    • (2009) Blood , vol.113 , pp. 784-792
    • Wadelius, M.1    Chen, L.Y.2    Lindh, J.D.3    Eriksson, N.4    Ghori, M.J.5
  • 3
    • 47949086046 scopus 로고    scopus 로고
    • Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin
    • Gage BF, Eby C, Johnson JA, Deych E, Rieder MJ, et al. (2008) Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin. Clin Pharmacol Ther 84: 326-331.
    • (2008) Clin Pharmacol Ther , vol.84 , pp. 326-331
    • Gage, B.F.1    Eby, C.2    Johnson, J.A.3    Deych, E.4    Rieder, M.J.5
  • 4
    • 63449117825 scopus 로고    scopus 로고
    • A Genome-Wide Association Study Confirms VKORC1, CYP2C9, and CYP4F2 as Principal Genetic Determinants of Warfarin Dose
    • Takeuchi F, McGinnis R, Bourgeois S, Barnes C, Eriksson N, et al. (2009) A Genome-Wide Association Study Confirms VKORC1, CYP2C9, and CYP4F2 as Principal Genetic Determinants of Warfarin Dose. PLoS Genet 5: e1000433.
    • (2009) PLoS Genet , vol.5
    • Takeuchi, F.1    McGinnis, R.2    Bourgeois, S.3    Barnes, C.4    Eriksson, N.5
  • 6
    • 77949756362 scopus 로고    scopus 로고
    • Genome-wide association studies in pharmacogenomics
    • Daly AK, (2010) Genome-wide association studies in pharmacogenomics. Nat Rev Genet 11: 241-6.
    • (2010) Nat Rev Genet , vol.11 , pp. 241-246
    • Daly, A.K.1
  • 7
    • 60849097257 scopus 로고    scopus 로고
    • Estimation of the warfarin dose with clinical and pharmacogenetic data
    • International Warfarin Pharmacogenetics Consortium
    • International Warfarin Pharmacogenetics Consortium, Klein TE, Altman RB, Eriksson N, Gage BF, et al. (2009) Estimation of the warfarin dose with clinical and pharmacogenetic data. N Engl J Med 360: 753-764.
    • (2009) N Engl J Med , vol.360 , pp. 753-764
    • Klein, T.E.1    Altman, R.B.2    Eriksson, N.3    Gage, B.F.4
  • 9
    • 73649109224 scopus 로고    scopus 로고
    • 10 years of oral anticoagulant pharmacogenomics: what difference will it make? A critical appraisal
    • Kurnik D, Loebstein R, Halkin H, Gak E, Almog S, (2009) 10 years of oral anticoagulant pharmacogenomics: what difference will it make? A critical appraisal. Pharmacogenomics 10: 1955-1965.
    • (2009) Pharmacogenomics , vol.10 , pp. 1955-1965
    • Kurnik, D.1    Loebstein, R.2    Halkin, H.3    Gak, E.4    Almog, S.5
  • 10
    • 78650447994 scopus 로고    scopus 로고
    • Practical recommendations for pharmacogenomics-based prescription: 2010 ESF-UB Conference on Pharmacogenetics and Pharmacogenomics
    • Becquemont L, Alfirevic A, Amstutz U, Brauch H, Jacqz-Aigrain E, et al. (2011) Practical recommendations for pharmacogenomics-based prescription: 2010 ESF-UB Conference on Pharmacogenetics and Pharmacogenomics. Pharmacogenomics 12: 113-124.
    • (2011) Pharmacogenomics , vol.12 , pp. 113-124
    • Becquemont, L.1    Alfirevic, A.2    Amstutz, U.3    Brauch, H.4    Jacqz-Aigrain, E.5
  • 11
    • 52449132783 scopus 로고    scopus 로고
    • U.S. Food and Drug Administration, Rockville, MD: FDA. Available:. Accessed 2008 May 19
    • U.S. Food and Drug Administration (2007) Press Release: FDA approves updated warfarin (Coumadin) prescribing information. Rockville, MD: FDA. Available: http://www.fda.gov/bbs/topics/NEWS/2007/NEW01684.html. Accessed 2008 May 19.
    • (2007) Press Release: FDA approves updated warfarin (Coumadin) prescribing information
  • 12
    • 84856772158 scopus 로고    scopus 로고
    • Evidence-based management of anticoagulant therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
    • Holbrook A, Schulman S, Witt DM, Vandvik PO, Fish J, et al. (2012) Evidence-based management of anticoagulant therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 141: e152S-84S.
    • (2012) Chest , vol.141
    • Holbrook, A.1    Schulman, S.2    Witt, D.M.3    Vandvik, P.O.4    Fish, J.5
  • 14
    • 66549110050 scopus 로고    scopus 로고
    • Pharmacogenetic relevance of CYP4F2 V433M polymorphism on acenocoumarol therapy
    • Pérez-Andreu V, Roldán V, Antón AI, García-Barberá N, Corral J, et al. (2009) Pharmacogenetic relevance of CYP4F2 V433M polymorphism on acenocoumarol therapy. Blood 113: 4977-4979.
    • (2009) Blood , vol.113 , pp. 4977-4979
    • Pérez-Andreu, V.1    Roldán, V.2    Antón, A.I.3    García-Barberá, N.4    Corral, J.5
  • 15
    • 80051512500 scopus 로고    scopus 로고
    • EU-PACT Study Group Loading and maintenance dose algorithms for phenprocoumon and acenocoumarol using patient characteristics and pharmacogenetic data
    • van Schie RM, Wessels JA, le Cessie S, de Boer A, Schalekamp T, et al. (2011) EU-PACT Study Group Loading and maintenance dose algorithms for phenprocoumon and acenocoumarol using patient characteristics and pharmacogenetic data. Eur Heart J 32: 1909-1917.
    • (2011) Eur Heart J , vol.32 , pp. 1909-1917
    • van Schie, R.M.1    Wessels, J.A.2    le Cessie, S.3    de Boer, A.4    Schalekamp, T.5
  • 16
    • 77955293789 scopus 로고    scopus 로고
    • A novel, single algorithm approach to predict acenocoumarol dose based on CYP2C9 and VKORC1 allele variants
    • Verde Z, Ruiz JR, Santiago C, Valle B, Bandrés F, et al. (2010) A novel, single algorithm approach to predict acenocoumarol dose based on CYP2C9 and VKORC1 allele variants. PLoS One 5: e11210.
    • (2010) PLoS One , vol.5
    • Verde, Z.1    Ruiz, J.R.2    Santiago, C.3    Valle, B.4    Bandrés, F.5
  • 17
    • 33947231296 scopus 로고    scopus 로고
    • A coding VKORC1 Asp36Tyr polymorphism predisposes to warfarin resistance
    • Loebstein R, Dvoskin I, Halkin H, Vecsler M, Lubetsky A, et al. (2007) A coding VKORC1 Asp36Tyr polymorphism predisposes to warfarin resistance. Blood 109: 2477-2480.
    • (2007) Blood , vol.109 , pp. 2477-2480
    • Loebstein, R.1    Dvoskin, I.2    Halkin, H.3    Vecsler, M.4    Lubetsky, A.5
  • 18
    • 78650962974 scopus 로고    scopus 로고
    • Thirteen novel VKORC1 mutations associated with oral anticoagulant resistance: insights into improved patient diagnosis and treatment
    • Watzka M, Geisen C, Bevans CG, Sittinger K, Spohn G, et al. (2011) Thirteen novel VKORC1 mutations associated with oral anticoagulant resistance: insights into improved patient diagnosis and treatment. J Thromb Haemost 9: 109-118.
    • (2011) J Thromb Haemost , vol.9 , pp. 109-118
    • Watzka, M.1    Geisen, C.2    Bevans, C.G.3    Sittinger, K.4    Spohn, G.5
  • 19
    • 52449098058 scopus 로고    scopus 로고
    • Pharmacodynamic resistance to warfarin is associated with nucleotide substitutions in VKORC1
    • Harrington DJ, Gorska R, Wheeler R, Davidson S, Murden S, et al. (2008) Pharmacodynamic resistance to warfarin is associated with nucleotide substitutions in VKORC1. J Thromb Haemost 6: 1663-1670.
    • (2008) J Thromb Haemost , vol.6 , pp. 1663-1670
    • Harrington, D.J.1    Gorska, R.2    Wheeler, R.3    Davidson, S.4    Murden, S.5
  • 20
    • 55449100859 scopus 로고    scopus 로고
    • VKORC1 polymorphisms, haplotypes and haplotype groups on warfarin dose among African-Americans and European-Americans
    • Limdi NA, Beasley TM, Crowley MR, Goldstein JA, Rieder MJ, et al. (2008) VKORC1 polymorphisms, haplotypes and haplotype groups on warfarin dose among African-Americans and European-Americans. Pharmacogenomics 9: 1445-1458.
    • (2008) Pharmacogenomics , vol.9 , pp. 1445-1458
    • Limdi, N.A.1    Beasley, T.M.2    Crowley, M.R.3    Goldstein, J.A.4    Rieder, M.J.5
  • 21
    • 51649084617 scopus 로고    scopus 로고
    • Regulatory polymorphism in vitamin K epoxide reductase complex subunit 1 (VKORC1) affects gene expression and warfarin dose requirement
    • Wang D, Chen H, Momary KM, Cavallari LH, Johnson JA, et al. (2008) Regulatory polymorphism in vitamin K epoxide reductase complex subunit 1 (VKORC1) affects gene expression and warfarin dose requirement. Blood 112: 1013-1021.
    • (2008) Blood , vol.112 , pp. 1013-1021
    • Wang, D.1    Chen, H.2    Momary, K.M.3    Cavallari, L.H.4    Johnson, J.A.5
  • 23
    • 43549104967 scopus 로고    scopus 로고
    • VKORC1 Asp36Tyr warfarin resistance marker is common in Ethiopian individuals
    • Aklillu E, Leong C, Loebstein R, Halkin H, Gak E, (2008) VKORC1 Asp36Tyr warfarin resistance marker is common in Ethiopian individuals. Blood 111: 3903-3904.
    • (2008) Blood , vol.111 , pp. 3903-3904
    • Aklillu, E.1    Leong, C.2    Loebstein, R.3    Halkin, H.4    Gak, E.5
  • 24
    • 40749123052 scopus 로고    scopus 로고
    • Warfarin pharmacogenetics: CYP2C9 and VKORC1 genotypes predict different sensitivity and resistance frequencies in the Ashkenazi and Sephardi Jewish populations
    • Scott SA, Edelmann L, Kornreich R, Desnick RJ, (2008) Warfarin pharmacogenetics: CYP2C9 and VKORC1 genotypes predict different sensitivity and resistance frequencies in the Ashkenazi and Sephardi Jewish populations. Am J Hum Genet 82: 495-500.
    • (2008) Am J Hum Genet , vol.82 , pp. 495-500
    • Scott, S.A.1    Edelmann, L.2    Kornreich, R.3    Desnick, R.J.4
  • 25
    • 84858382877 scopus 로고    scopus 로고
    • Evaluation of the warfarin-resistance polymorphism, VKORC1 Asp36Tyr, and its effect on dosage algorithms in a genetically heterogeneous anticoagulant clinic
    • Shuen AY, Wong BY, Fu L, Selby R, Cole DE, (2012) Evaluation of the warfarin-resistance polymorphism, VKORC1 Asp36Tyr, and its effect on dosage algorithms in a genetically heterogeneous anticoagulant clinic. Clin Biochem 45: 397-401.
    • (2012) Clin Biochem , vol.45 , pp. 397-401
    • Shuen, A.Y.1    Wong, B.Y.2    Fu, L.3    Selby, R.4    Cole, D.E.5
  • 26
    • 47649112371 scopus 로고    scopus 로고
    • Multiple genetic alterations in vitamin K epoxide reductase complex subunit 1 gene (VKORC1) can explain the high dose requirement during oral anticoagulation in humans
    • Bodin L, Perdu J, Diry M, Horellou MH, Loriot MA, (2008) Multiple genetic alterations in vitamin K epoxide reductase complex subunit 1 gene (VKORC1) can explain the high dose requirement during oral anticoagulation in humans. J Thromb Haemost 6: 1436-1439.
    • (2008) J Thromb Haemost , vol.6 , pp. 1436-1439
    • Bodin, L.1    Perdu, J.2    Diry, M.3    Horellou, M.H.4    Loriot, M.A.5
  • 27
    • 61449103718 scopus 로고    scopus 로고
    • Novel mutations in the VKORC1 gene of wild rats and mice--a response to 50 years of selection pressure by warfarin?
    • Rost S, Pelz HJ, Menzel S, MacNicoll AD, León V, et al. (2009) Novel mutations in the VKORC1 gene of wild rats and mice--a response to 50 years of selection pressure by warfarin? BMC Genet 10: 4-12.
    • (2009) BMC Genet , vol.10 , pp. 4-12
    • Rost, S.1    Pelz, H.J.2    Menzel, S.3    MacNicoll, A.D.4    León, V.5
  • 28
    • 11244332058 scopus 로고    scopus 로고
    • A polymorphism in the VKORC1 gene is associated with an interindividual variability in the dose-anticoagulant effect of warfarin
    • D'Andrea G, D'Ambrosio RL, Di Perna P, Chetta M, Santacroce R, et al. (2005) A polymorphism in the VKORC1 gene is associated with an interindividual variability in the dose-anticoagulant effect of warfarin. Blood 105: 645-649.
    • (2005) Blood , vol.105 , pp. 645-649
    • D'Andrea, G.1    D'Ambrosio, R.L.2    Di Perna, P.3    Chetta, M.4    Santacroce, R.5
  • 29
    • 79960777339 scopus 로고    scopus 로고
    • Novel CYP2C9 and VKORC1 gene variants associated with warfarin dosage variability in the South African black population
    • Mitchell C, Gregersen N, Krause A, (2011) Novel CYP2C9 and VKORC1 gene variants associated with warfarin dosage variability in the South African black population. Pharmacogenomics 12: 953-963.
    • (2011) Pharmacogenomics , vol.12 , pp. 953-963
    • Mitchell, C.1    Gregersen, N.2    Krause, A.3
  • 30
    • 80052964856 scopus 로고    scopus 로고
    • Understanding the contribution of synonymous mutations to human disease
    • Sauna ZE, Kimchi-Sarfaty C, (2011) Understanding the contribution of synonymous mutations to human disease. Nat Rev Genet 12: 683-691.
    • (2011) Nat Rev Genet , vol.12 , pp. 683-691
    • Sauna, Z.E.1    Kimchi-Sarfaty, C.2
  • 31
    • 77958129007 scopus 로고    scopus 로고
    • Gamma-glutamyl carboxylase and its influence on warfarin dose
    • King CR, Deych E, Milligan P, Eby C, Lenzini P, et al. (2010) Gamma-glutamyl carboxylase and its influence on warfarin dose. Thromb Haemost 104: 750-754.
    • (2010) Thromb Haemost , vol.104 , pp. 750-754
    • King, C.R.1    Deych, E.2    Milligan, P.3    Eby, C.4    Lenzini, P.5
  • 32
    • 34447636585 scopus 로고    scopus 로고
    • The genetic interaction between VKORC1 c1173t and calumenin a29809g modulates the anticoagulant response of acenocoumarol
    • González-Conejero R, Corral J, Roldán V, Ferrer F, Sánchez-Serrano I, et al. (2007) The genetic interaction between VKORC1 c1173t and calumenin a29809g modulates the anticoagulant response of acenocoumarol. J Thromb Haemost 5: 1701-1706.
    • (2007) J Thromb Haemost , vol.5 , pp. 1701-1706
    • González-Conejero, R.1    Corral, J.2    Roldán, V.3    Ferrer, F.4    Sánchez-Serrano, I.5
  • 33
    • 84864609288 scopus 로고    scopus 로고
    • Copy number variation detection and genotyping from exome sequence data
    • Krumm N, Sudmant PH, Ko A, O'Roak BJ, Malig M, et al. (2012) Copy number variation detection and genotyping from exome sequence data. Genome Res 22: 1525-1532.
    • (2012) Genome Res , vol.22 , pp. 1525-1532
    • Krumm, N.1    Sudmant, P.H.2    Ko, A.3    O'Roak, B.J.4    Malig, M.5


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