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Volumn 110, Issue 20, 2013, Pages 8099-8104

Autocrine signaling based selection of combinatorial antibodies that transdifferentiate human stem cells

Author keywords

Growth factors; Neuralgenisis; Phenotypic selections

Indexed keywords

ANTIBODY; F ACTIN; GRANULOCYTE COLONY STIMULATING FACTOR RECEPTOR; NESTIN; PLATELET DERIVED GROWTH FACTOR; THROMBOPOIETIN; TUBULIN;

EID: 84877871396     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1306263110     Document Type: Article
Times cited : (53)

References (38)
  • 1
    • 84866847222 scopus 로고    scopus 로고
    • Selectifon of antibodies that regulate phenotype from intracellular combinatorial antibody libraries
    • Zhang H, Wilson IA, Lerner RA (2012) Selectifon of antibodies that regulate phenotype from intracellular combinatorial antibody libraries. Proc Natl Acad Sci USA 109(39):15728-15733.
    • (2012) Proc Natl Acad Sci USA , vol.109 , Issue.39 , pp. 15728-15733
    • Zhang, H.1    Wilson, I.A.2    Lerner, R.A.3
  • 5
    • 0025226085 scopus 로고
    • Phage antibodies: Filamentous phage displaying antibody variable domains
    • McCafferty J, Griffiths AD, Winter G, Chiswell DJ (1990) Phage antibodies: Filamentous phage displaying antibody variable domains. Nature 348(6301):552-554. (Pubitemid 120015109)
    • (1990) Nature , vol.348 , Issue.6301 , pp. 552-554
    • McCafferty, J.1    Griffiths, A.D.2    Winter, G.3    Chiswell, D.J.4
  • 7
    • 33845726659 scopus 로고    scopus 로고
    • Manufacturing immunity to disease in a test tube: The magic bullet realized
    • DOI 10.1002/anie.200603381
    • Lerner RA (2006) Manufacturing immunity to disease in a test tube: The magic bullet realized. Angew Chem Int Ed Engl 45(48):8106-8125. (Pubitemid 44974142)
    • (2006) Angewandte Chemie - International Edition , vol.45 , Issue.48 , pp. 8106-8125
    • Lerner, R.A.1
  • 8
    • 0035182533 scopus 로고    scopus 로고
    • Stem and progenitor cells: Origins, phenotypes, lineage commitments, and transdifferentiations
    • DOI 10.1146/annurev.cellbio.17.1.387
    • Weissman IL, Anderson DJ, Gage F (2001) Stem and progenitor cells: Origins, phenotypes, lineage commitments, and transdifferentiations. Annu Rev Cell Dev Biol 17:387-403. (Pubitemid 33096181)
    • (2001) Annual Review of Cell and Developmental Biology , vol.17 , pp. 387-403
    • Weissman, I.L.1    Anderson, D.J.2    Gage, F.3
  • 9
    • 82755182204 scopus 로고    scopus 로고
    • Historical origins of transdifferentiation and reprogramming
    • Graf T (2011) Historical origins of transdifferentiation and reprogramming. Cell Stem Cell 9(6):504-516.
    • (2011) Cell Stem Cell , vol.9 , Issue.6 , pp. 504-516
    • Graf, T.1
  • 10
    • 0015815954 scopus 로고
    • Normal distribution, patching and capping of lymphocyte surface immunoglobulin studied by electron microscopy
    • de Petris S, Raff MC (1973) Normal distribution, patching and capping of lymphocyte surface immunoglobulin studied by electron microscopy. Nat New Biol 241(113):257-259.
    • (1973) Nat New Biol , vol.241 , Issue.113 , pp. 257-259
    • De Petris, S.1    Raff, M.C.2
  • 11
    • 0025998618 scopus 로고
    • Actin dynamics in growth cones
    • Okabe S, Hirokawa N (1991) Actin dynamics in growth cones. J Neurosci 11(7): 1918-1929.
    • (1991) J Neurosci , vol.11 , Issue.7 , pp. 1918-1929
    • Okabe, S.1    Hirokawa, N.2
  • 12
    • 0020634283 scopus 로고
    • Differences in the organization of actin in the growth cones compared with the neurites of cultured neurons from chick embryos
    • Letourneau PC (1983) Differences in the organization of actin in the growth cones compared with the neurites of cultured neurons from chick embryos. J Cell Biol 97(4):963-973. (Pubitemid 13019355)
    • (1983) Journal of Cell Biology , vol.97 , Issue.4 , pp. 963-973
    • Letourneau, P.C.1
  • 13
    • 24944455102 scopus 로고    scopus 로고
    • Activation of the PI3-K/Akt pathway mediates cGMP enhanced-neurogenesis in the adult progenitor cells derived from the subventricular zone
    • DOI 10.1038/sj.jcbfm.9600112
    • Wang L, Gang Zhang Z, Lan Zhang R, Chopp M (2005) Activation of the PI3-K/Akt pathway mediates cGMP enhanced-neurogenesis in the adult progenitor cells derived from the subventricular zone. J Cereb Blood Flow Metab 25(9):1150-1158. (Pubitemid 41710741)
    • (2005) Journal of Cerebral Blood Flow and Metabolism , vol.25 , Issue.9 , pp. 1150-1158
    • Wang, L.1    Zhang, Z.G.2    Zhang, R.L.3    Chopp, M.4
  • 14
    • 0037203907 scopus 로고    scopus 로고
    • Dehydroepiandrosterone (DHEA) and its sulfated derivative (DHEAS) regulate apoptosis during neurogenesis by triggering the Akt signaling pathway in opposing ways
    • DOI 10.1016/S0169-328X(01)00315-1, PII S0169328X01003151
    • Zhang L, et al. (2002) Dehydroepiandrosterone (DHEA) and its sulfated derivative (DHEAS) regulate apoptosis during neurogenesis by triggering the Akt signaling pathway in opposing ways. Brain Res Mol Brain Res 98(1-2):58-66. (Pubitemid 34142279)
    • (2002) Molecular Brain Research , vol.98 , Issue.1-2 , pp. 58-66
    • Zhang, L.1    Li, B.S.2    Ma, W.3    Barker, J.L.4    Chang, Y.H.5    Zhao, W.6    Rubinow, D.R.7
  • 15
    • 33845999883 scopus 로고    scopus 로고
    • Nitric oxide decreases subventricular zone stem cell proliferation by inhibition of epidermal growth factor receptor and phosphoinositide-3-kinase/Akt pathway
    • DOI 10.1634/stemcells.2006-0131
    • Torroglosa A, et al. (2007) Nitric oxide decreases subventricular zone stem cell proliferation by inhibition of epidermal growth factor receptor and phosphoinositide-3-kinase/Akt pathway. Stem Cells 25(1):88-97. (Pubitemid 46052978)
    • (2007) Stem Cells , vol.25 , Issue.1 , pp. 88-97
    • Torroglosa, A.1    Murillo-Carretero, M.2    Romero-Grimaldi, C.3    Matarredona, E.R.4    Campos-Caro, A.5    Estrada, C.6
  • 16
    • 33746808398 scopus 로고    scopus 로고
    • Wnt/β-catenin signaling in development and disease
    • Clevers H (2006) Wnt/β-catenin signaling in development and disease. Cell 127(3): 469-480.
    • (2006) Cell , vol.127 , Issue.3 , pp. 469-480
    • Clevers, H.1
  • 17
    • 84873446404 scopus 로고    scopus 로고
    • Hedgehog regulates Norrie disease protein to drive neural progenitor self-renewal
    • McNeill B, et al. (2013) Hedgehog regulates Norrie disease protein to drive neural progenitor self-renewal. Hum Mol Genet 22(5):1005-1016.
    • (2013) Hum Mol Genet , vol.22 , Issue.5 , pp. 1005-1016
    • McNeill, B.1
  • 19
    • 84855398689 scopus 로고    scopus 로고
    • Impedance responses reveal β2-adrenergic receptor signaling pluridimensionality and allow classification of ligands with distinct signaling profiles
    • Stallaert W, Dorn JF, van der Westhuizen E, Audet M, Bouvier M (2012) Impedance responses reveal β2-adrenergic receptor signaling pluridimensionality and allow classification of ligands with distinct signaling profiles. PLoS ONE 7(1):e29420.
    • (2012) PLoS ONE , vol.7 , Issue.1
    • Stallaert, W.1    Dorn, J.F.2    Van Der Westhuizen, E.3    Audet, M.4    Bouvier, M.5
  • 20
    • 78751498756 scopus 로고    scopus 로고
    • Functional selectivity and biased receptor signaling
    • Kenakin T (2011) Functional selectivity and biased receptor signaling. J Pharmacol Exp Ther 336(2):296-302.
    • (2011) J Pharmacol Exp Ther , vol.336 , Issue.2 , pp. 296-302
    • Kenakin, T.1
  • 21
    • 79960502280 scopus 로고    scopus 로고
    • Ligand functional selectivity and quantitative pharmacology at G protein-coupled receptors
    • Stallaert W, Christopoulos A, Bouvier M (2011) Ligand functional selectivity and quantitative pharmacology at G protein-coupled receptors. Expert Opin Drug Discov 6(8):811-825.
    • (2011) Expert Opin Drug Discov , vol.6 , Issue.8 , pp. 811-825
    • Stallaert, W.1    Christopoulos, A.2    Bouvier, M.3
  • 22
    • 34447642715 scopus 로고    scopus 로고
    • The evasive nature of drug efficacy: implications for drug discovery
    • DOI 10.1016/j.tips.2007.06.005, PII S0165614707001502, Allosterism and Collateral Efficacy
    • Galandrin S, Oligny-Longpré G, Bouvier M (2007) The evasive nature of drug efficacy: Implications for drug discovery. Trends Pharmacol Sci 28(8):423-430. (Pubitemid 47087968)
    • (2007) Trends in Pharmacological Sciences , vol.28 , Issue.8 , pp. 423-430
    • Galandrin, S.1    Oligny-Longpre, G.2    Bouvier, M.3
  • 23
    • 77952354490 scopus 로고    scopus 로고
    • Seven transmembrane receptors as shapeshifting proteins: The impact of allosteric modulation and functional selectivity on new drug discovery
    • Kenakin T, Miller LJ (2010) Seven transmembrane receptors as shapeshifting proteins: The impact of allosteric modulation and functional selectivity on new drug discovery. Pharmacol Rev 62(2):265-304.
    • (2010) Pharmacol Rev , vol.62 , Issue.2 , pp. 265-304
    • Kenakin, T.1    Miller, L.J.2
  • 24
    • 0033955777 scopus 로고    scopus 로고
    • Morphogen gradients. A question of time or concentration?
    • DOI 10.1016/S0168-9525(99)01880-6, PII S0168952599018806
    • Pagès F, Kerridge S (2000) Morphogen gradients. A question of time or concentration? Trends Genet 16(1):40-44. (Pubitemid 30062237)
    • (2000) Trends in Genetics , vol.16 , Issue.1 , pp. 40-44
    • Pages, F.1    Kerridge, S.2
  • 25
    • 77954746410 scopus 로고    scopus 로고
    • Dynamic assignment and maintenance of positional identity in the ventral neural tube by the morphogen sonic hedgehog
    • Dessaud E, et al. (2010) Dynamic assignment and maintenance of positional identity in the ventral neural tube by the morphogen sonic hedgehog. PLoS Biol 8(6):e1000382.
    • (2010) PLoS Biol , vol.8 , Issue.6
    • Dessaud, E.1
  • 27
    • 84856094426 scopus 로고    scopus 로고
    • Gene regulatory logic for reading the Sonic Hedgehog signaling gradient in the vertebrate neural tube
    • Balaskas N, et al. (2012) Gene regulatory logic for reading the Sonic Hedgehog signaling gradient in the vertebrate neural tube. Cell 148(1-2):273-284.
    • (2012) Cell , vol.148 , Issue.1-2 , pp. 273-284
    • Balaskas, N.1
  • 28
    • 4644328190 scopus 로고    scopus 로고
    • Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities
    • DOI 10.1016/j.cell.2004.07.024, PII S0092867404007123
    • Harfe BD, et al. (2004) Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities. Cell 118(4):517-528. (Pubitemid 39485670)
    • (2004) Cell , vol.118 , Issue.4 , pp. 517-528
    • Harfe, B.D.1    Scherz, P.J.2    Nissim, S.3    Tian, H.4    McMahon, A.P.5    Tabin, C.J.6
  • 29
    • 4043122029 scopus 로고    scopus 로고
    • Dynamic changes in the response of cells to positive hedgehog signaling during mouse limb patterning
    • DOI 10.1016/j.cell.2004.07.023, PII S0092867404007111
    • Ahn S, Joyner AL (2004) Dynamic changes in the response of cells to positive hedgehog signaling during mouse limb patterning. Cell 118(4):505-516. (Pubitemid 39485669)
    • (2004) Cell , vol.118 , Issue.4 , pp. 505-516
    • Ahn, S.1    Joyner, A.L.2
  • 30
    • 84856698420 scopus 로고    scopus 로고
    • Endocytosis and signaling: Cell logistics shape the eukaryotic cell plan
    • Sigismund S, et al. (2012) Endocytosis and signaling: Cell logistics shape the eukaryotic cell plan. Physiol Rev 92(1):273-366.
    • (2012) Physiol Rev , vol.92 , Issue.1 , pp. 273-366
    • Sigismund, S.1
  • 31
    • 33747195353 scopus 로고    scopus 로고
    • Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
    • DOI 10.1016/j.cell.2006.07.024, PII S0092867406009767
    • Takahashi K, Yamanaka S (2006) Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126(4):663-676. (Pubitemid 44233629)
    • (2006) Cell , vol.126 , Issue.4 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 32
    • 84859710791 scopus 로고    scopus 로고
    • Seeing old friends from a different angle: Novel properties of hematopoietic growth factors in the healthy and diseased brain
    • Diederich K, Schäbitz W-R, Minnerup J (2012) Seeing old friends from a different angle: Novel properties of hematopoietic growth factors in the healthy and diseased brain. Hippocampus 22(5):1051-1057.
    • (2012) Hippocampus , vol.22 , Issue.5 , pp. 1051-1057
    • Diederich, K.1    Schäbitz, W.-R.2    Minnerup, J.3
  • 34
    • 42549091223 scopus 로고    scopus 로고
    • The receptor for granulocyte-colony stimulating factor (G-CSF) is expressed in radial glia during development of the nervous system
    • Kirsch F, Krüger C, Schneider A (2008) The receptor for granulocyte-colony stimulating factor (G-CSF) is expressed in radial glia during development of the nervous system. BMC Dev Biol 8:32-39.
    • (2008) BMC Dev Biol , vol.8 , pp. 32-39
    • Kirsch, F.1    Krüger, C.2    Schneider, A.3
  • 35
    • 0029856943 scopus 로고    scopus 로고
    • Multiple signaling pathways induced by granulocyte colony-stimulating factor involving activation of JAKs, STAT5, and/or STAT3 are required for regulation of three distinct classes of immediate early genes
    • Tian S-S, et al. (1996) Multiple signaling pathways induced by granulocyte colonystimulating factor involving activation of JAKs, STAT5, and/or STAT3 are required for regulation of three distinct classes of immediate early genes. Blood 88(12):4435-4444. (Pubitemid 26419126)
    • (1996) Blood , vol.88 , Issue.12 , pp. 4435-4444
    • Tian, S.-S.1    Tapley, P.2    Sincich, C.3    Stein, R.B.4    Rosen, J.5    Lamb, P.6
  • 36
    • 0034699390 scopus 로고    scopus 로고
    • Cell-fate conversion of lymphoid-committed progenitors by instructive actions of cytokines
    • Kondo M, et al. (2000) Cell-fate conversion of lymphoid-committed progenitors by instructive actions of cytokines. Nature 407(6802):383-386.
    • (2000) Nature , vol.407 , Issue.6802 , pp. 383-386
    • Kondo, M.1
  • 38
    • 84864527751 scopus 로고    scopus 로고
    • Cord blood-derived neuronal cells by ectopic expression of Sox2 and c-Myc
    • Giorgetti A, et al. (2012) Cord blood-derived neuronal cells by ectopic expression of Sox2 and c-Myc. Proc Natl Acad Sci USA 109(31):12556-12561.
    • (2012) Proc Natl Acad Sci USA , vol.109 , Issue.31 , pp. 12556-12561
    • Giorgetti, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.