Effect of TangMaiJiaoTai on regulating the glycolipid metabolism and the production of glucokinase and low density lipoprotein receptor protein in diabetic rats with hyperlipidemia

Chinese Pharmacological Bulletin

Volumn 29, Issue 2, 2013, Pages 234-237

  Chang, Xiu Ting ^a   Li, Jie ^a   Xie, Xi ^a   Huang, Kai Peng ^a   Huang, He Qing ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Diabetic rats; Glucokinase; HbA1c; LDL receptor; Liver glycogen; TangMaiJiaoTai

Indexed keywords

CHINESE DRUG; CHOLESTEROL; GLUCOKINASE; GLUCOSE; GLYCOGEN; GLYCOLIPID; GLYCOSYLATED PLASMA PROTEIN; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN RECEPTOR; PLASMA PROTEIN; TANG MAI JIAO TAI; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIABETES MELLITUS; ENZYME REGULATION; GLUCOSE BLOOD LEVEL; GLYCOGEN LIVER LEVEL; HEMOGLOBIN BLOOD LEVEL; HYPERLIPIDEMIA; LIPID METABOLISM; METABOLIC REGULATION; NONHUMAN; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN SECRETION; RAT; TREATMENT RESPONSE; TRIACYLGLYCEROL BLOOD LEVEL; WESTERN BLOTTING;

EID: 84877870604     PISSN: 10011978     EISSN: None     Source Type: Journal    
DOI: 10.3969/j.issn.1001-1978.2013.02.20     Document Type: Article

References (9)

1. 1c measurement improves the detection of type 2 diabetes in high-risk individuals with nondiagnostic levels of fasting plasma glucose: the Early Diabetes Intervention Program (EDIP)[J]. Diabetes Care,2001,24(3):465-71.
2. Goldstein D E, Little R R, Lorenz R A, et al. Tests of glycemia in diabetes [J]. Diabetes care,2004,27(7):1761-73. (Pubitemid 38857461)
3. Xu L, Zhao Y K, Gong H H, et al. Relationship between dyslipidemia and diabetic retinopathy in type 2 diabetes mellitus [J]. Shaanxi Med J,2012,41(6):691-2.
4. Basu A, Basu R, Shah P, et al. Type 2 diabetes impairs splanchnic uptake of glucose but does not alter intestinal glucose absorption during enteral glucose feeding : additional evidence for a defect in hepatic glucokinase activity [J]. Diabetes,2001,50(6):1351-62. (Pubitemid 32500168)
5. Agius L. New hepatic targets for glycaemic control in diabetes[J]. Best Pract Res Clin Endocrinol Metab,2007,21(4):587-605. (Pubitemid 350177566)
6. Huang H, Shen Z F. The research of the glucokinase target for the treatment of diabetes [J]. Chin Pharmacol Bull,2006,22(9):1025-9. (Pubitemid 44912554)
7. Wang Y L, Fan C L, Dou X B. Effect of gypenosides on the expression of LDL-R in HepG2[J]. Chin Pharmacol Bull,2010,26(1):138-9.
8. Goldstein J L, Brown M S. Regulation of the mevalonate pathway [J]. Nature,1990,343(6257):425-30.
9. Zelcer N, Hong C, Boyadjian R, Tontonoz P. LXR regulates cholesterol uptake through Idol - dependent ubiquitination of the LDL receptor[J]. Sci,2009,325(5936):100-4.