-
1
-
-
84892818859
-
-
http://www.cbn.com/cbnnews/healthscience/2012/November/ Deanna-Protocol-a-Breakthrough-for-Lou-Gehrigs/.
-
-
-
-
3
-
-
0027752805
-
The larginine-nitric oxide pathway
-
Moncada S, H iggs A. T he L-arginine-nitric oxide pathway. N Engl J Med. 1993; 329 : 2002-12
-
(1993)
N Engl J Med
, vol.329
, pp. 2002-2012
-
-
Moncada, S.1
Higgs, A.2
-
4
-
-
84864461350
-
Improved training tolerance by supplementation with alpha-keto acids in untrained young adults: A randomized, double-blind, placebo-controlled trial
-
Liu Y, L ange R, L angansky J, H amma T, Y ang B, S teinacker JM. Improved training tolerance by supplementation with alpha-keto acids in untrained young adults: A randomized, double-blind, placebo-controlled trial. J Int Soc Sports Nutr. 2012; 9 : 37
-
(2012)
J Int Soc Sports Nutr
, vol.9
, pp. 37
-
-
Liu, Y.1
Lange, R.2
Langansky, J.3
Hamma, T.4
Yang, B.5
Steinacker, J.M.6
-
5
-
-
0026032042
-
Alpha-ketoglutarate preserves protein synthesis and free glutamine in skeletal muscle after surgery
-
Hammarqvist F, W ernerman J, v on der Decken A, Vinnars E. Alpha-ketoglutarate preserves protein synthesis and free glutamine in skeletal muscle after surgery. Surgery. 1991; 109 : 28-36
-
(1991)
Surgery
, vol.109
, pp. 28-36
-
-
Hammarqvist, F.1
Wernerman, J.2
Von Der Decken, A.3
Vinnars, E.4
-
6
-
-
22244483765
-
Glutamine and arginine: Immunonutrients and metabolic modulators?
-
DOI 10.1097/00003677-200507000-00001
-
Joyner M J. G lutamine and arginine: Immunonutrients and metabolic modulators? Exerc Sport Sci Rev. 2005; 33 : 105-6 (Pubitemid 40994561)
-
(2005)
Exercise and Sport Sciences Reviews
, vol.33
, Issue.3
, pp. 105-106
-
-
Joyner, M.J.1
-
7
-
-
84867823334
-
Chemical and technological delivery systems for idebenone: A review of literature production
-
Carbone C, P ignatello R, M usumeci T, P uglisi G. C hemical and technological delivery systems for idebenone: A review of literature production. Expert Opin Drug Deliv. 2012; 9 : 1377-92
-
(2012)
Expert Opin Drug Deliv
, vol.9
, pp. 1377-1392
-
-
Carbone, C.1
Pignatello, R.2
Musumeci, T.3
Puglisi, G.4
-
8
-
-
84863575129
-
Decreased motor cortex gamma-aminobutyric acid in amyotrophic lateral sclerosis
-
Foerster B R, C allaghan B C, P etrou M, E dden R AE, Chenevert TL, Feldman EL. Decreased motor cortex gamma-aminobutyric acid in amyotrophic lateral sclerosis. Neurology. 2012; 78 : 1596-600
-
(2012)
Neurology
, vol.78
, pp. 1596-1600
-
-
Foerster, B.R.1
Callaghan, B.C.2
Petrou, M.3
Edden, R.A.E.4
Chenevert, T.L.5
Feldman, E.L.6
-
9
-
-
79958239154
-
Glutamate and glutathione interplay in a motor neuronal model of amyotrophic lateral sclerosis reveals altered energy metabolism
-
D'Alessandro G, C alcagno E, T artari S, R izzardini M, Invernizzi R, Cantoni L. Glutamate and glutathione interplay in a motor neuronal model of amyotrophic lateral sclerosis reveals altered energy metabolism. Neurobiol Dis. 2011; 43 : 346-55
-
(2011)
Neurobiol Dis
, vol.43
, pp. 346-355
-
-
D'Alessandro, G.1
Calcagno, E.2
Tartari, S.3
Rizzardini, M.4
Invernizzi, R.5
Cantoni, L.6
-
10
-
-
84857061515
-
Mitochondrial pathobiology in ALS
-
Martin LJ. M itochondrial pathobiology in ALS. J Bioenerg Biomembr. 2011; 43 : 569-79
-
(2011)
J Bioenerg Biomembr
, vol.43
, pp. 569-579
-
-
Martin, L.J.1
-
11
-
-
0031716355
-
Mitochondria in sporadic amyotrophic lateral sclerosis
-
DOI 10.1006/exnr.1998.6866
-
Swerdlow R H, P arks J, C assarino D, T rimmer P, M iller S, Maguire D.et al. Mitochondria in sporadic amyotrophic lateral sclerosis. Exp Neurol. 1998; 153 : 135-42 (Pubitemid 28452305)
-
(1998)
Experimental Neurology
, vol.153
, Issue.1
, pp. 135-142
-
-
Swerdlow, R.H.1
Parks, J.K.2
Cassarino, D.S.3
Trimmer, P.A.4
Miller, S.W.5
Maguire, D.J.6
Sheehan, J.P.7
Maguire, R.S.8
Pattee, G.9
Juel, V.C.10
Phillips, L.H.11
Tuttle, J.B.12
Bennett Jr., J.P.13
Davis, R.E.14
Parker Jr., W.D.15
-
12
-
-
0142217904
-
D-β-Hydroxybutyrate rescues mitochondrial respiration and mitigates features of Parkinson disease
-
DOI 10.1172/JCI200318797
-
Tieu K, P erier C, C aspersen C, T eismann P, W u DC, Yan S.D.et al. D-beta-hydroxybutyrate rescues mitochondrial respiration and mitigates features of Parkinson's disease. J Clin Invest. 2003; 112 : 892-901 (Pubitemid 38063747)
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.6
, pp. 892-901
-
-
Tieu, K.1
Perier, C.2
Caspersen, C.3
Teismann, P.4
Wu, D.-C.5
Yan, S.-D.6
Naini, A.7
Vila, M.8
Jackson-Lewis, V.9
Ramasamy, R.10
Przedborski, S.11
-
13
-
-
84859621752
-
He complex molecular biology of amyotrophic lateral sclerosis (ALS)
-
Redler RL, D okholyan NV. T he complex molecular biology of amyotrophic lateral sclerosis (ALS). Prog Mol Biol Transl Sci. 2012; 107 : 215-62
-
(2012)
Prog Mol Biol Transl Sci
, vol.107
, pp. 215-262
-
-
Redler, R.L.1
Dokholyan, N.V.2
-
14
-
-
0035516124
-
From Charcot to Lou Gehrig: Deciphering selective motor neuron death in ALS
-
DOI 10.1038/35097565
-
Cleveland D W, R othstein J. F rom Charcot to Lou Gehrig: Deciphering selective motor neuron death in ALS. Nat Rev Neurosci. 2001; 2 : 806-19 (Pubitemid 33674062)
-
(2001)
Nature Reviews Neuroscience
, vol.2
, Issue.11
, pp. 806-819
-
-
Cleveland, D.W.1
Rothstein, J.D.2
-
15
-
-
0029731655
-
A confirmatory dose-ranging study of riluzole in ALS
-
Lacomblez L, B ensimon G, L eigh PN, G uillet P, P owe L, Durrleman S, et al. A confi rmatory dose-ranging study of riluzole in ALS. ALS/Riluzole Study Group-II. Neurology. 1996; 47(Suppl 4) : S242-50 (Pubitemid 26422577)
-
(1996)
Neurology
, vol.47
, Issue.6 SUPPL. 4
-
-
Lacomblez, L.1
Bensimon, G.2
Leigh, P.N.3
Guillet, P.4
Powe, L.5
Durrleman, S.6
Delumeau, J.C.7
Meininger, V.8
-
16
-
-
84867320492
-
N rf2/ARE signaling pathway: Key mediator in oxidative stress and potential therapeutic target in als
-
Petri S, K orner S, K iaei M. N rf2/ARE Signaling Pathway: Key Mediator in Oxidative Stress and Potential Therapeutic Target in ALS. Neurol Res Int. 2012 ; 2012 : 878030
-
(2012)
Neurol Res Int
, vol.2012
, pp. 878030
-
-
Petri, S.1
Korner, S.2
Kiaei, M.3
-
17
-
-
0037107997
-
Copper/zinc superoxide dismutase overexpression promotes survival of cortical neurons exposed to neurotoxins in vitro
-
Borg J, L ondon J. Copper/zinc superoxide dismutase overexpression promotes survival of cortical neurons exposed to neurotoxins in vitro. J Neurosci Res. 2002; 70 : 180-9
-
(2002)
J Neurosci Res
, vol.70
, pp. 180-189
-
-
Borg, J.1
London, J.2
-
19
-
-
33745816384
-
Aketogenic diet as a potential novel therapeutic intervention in amyotrophic lateral sclerosis
-
Zhao Z, L ange D, V oustianiouk A, M acGrogan D, H o L, Suh J, et al. A ketogenic diet as a potential novel therapeutic intervention in amyotrophic lateral sclerosis. BMC Neurosci. 2006; 7 : 29
-
(2006)
BMC Neurosci
, vol.7
, pp. 29
-
-
Zhao, Z.1
Lange, D.2
Voustianiouk, A.3
MacGrogan, D.4
Ho, L.5
Suh, J.6
-
20
-
-
0032555066
-
Coenzyme Q10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects
-
Matthews R T, Y ang L, B rowne S, B ajk M, B eal M F. Coenzyme Q10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects. Proc Natl Acad Sci U S A. 1998; 95 : 8892-7
-
(1998)
Proc Natl Acad Sci U S A.
, vol.95
, pp. 8892-8897
-
-
Matthews, R.T.1
Yang, L.2
Browne, S.3
Bajk, M.4
Beal, M.F.5
-
21
-
-
0033051815
-
Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis
-
DOI 10.1038/6568
-
Klivenyi P, F errante RJ, M atthews RT, B ogdanov MB, Klein AM, Andreassen O.A.et al. Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis. Nature Medicine. 1999; 5 : 347-50 (Pubitemid 29124375)
-
(1999)
Nature Medicine
, vol.5
, Issue.3
, pp. 347-350
-
-
Klivenyi, P.1
Ferrante, R.J.2
Matthews, R.T.3
Bogdanov, M.B.4
Klein, A.M.5
Andreassen, O.A.6
Mueller, G.7
Wermer, M.8
Kaddurah-Daouk, R.9
Beal, M.F.10
-
22
-
-
70249116820
-
Phase II trial of CoQ10 for ALS fi nds insuffi cient evidence to justify phase III
-
Kaufmann P, T hompson J L, L evy G, B uschsbaum R, Shefner J, Krivickas L.et al. Phase II trial of CoQ10 for ALS fi nds insuffi cient evidence to justify phase III. Ann Neurol. 2009; 66 : 235-44
-
(2009)
Ann Neurol
, vol.66
, pp. 235-244
-
-
Kaufmann, P.1
Thompson, J.L.2
Levy, G.3
Buschsbaum, R.4
Shefner, J.5
Krivickas, L.6
-
24
-
-
74849099092
-
Methionine sulfoximine, an inhibitor of glutamine synthetase, lowers brain glutamine and glutamate in a mouse model of ALS
-
Ghoddoussi F, G alloway MP, J ambekar A, B ame M, Needleman R, Brusilow WS. Methionine sulfoximine, an inhibitor of glutamine synthetase, lowers brain glutamine and glutamate in a mouse model of ALS. J Neurol Sci. 2010; 290 : 41-7
-
(2010)
J Neurol Sci
, vol.290
, pp. 41-47
-
-
Ghoddoussi, F.1
Galloway, M.P.2
Jambekar, A.3
Bame, M.4
Needleman, R.5
Brusilow, W.S.6
-
25
-
-
0041421277
-
Glutamate carboxypeptidase II inhibition protects motor neurons from death in familial amyotrophic lateral sclerosis models
-
DOI 10.1073/pnas.1530168100
-
Ghadge G D, S lusher B, B odner A, D al Canto M, Wozniak K, Thomas A.et al. Glutamate carboxypeptidase II inhibition protects motor neurons from death in familial amyotrophic lateral sclerosis models. Proc Natl Acad Sci U S A. 2003; 100 : 9554-9 (Pubitemid 37033966)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.16
, pp. 9554-9559
-
-
Ghadge, G.D.1
Slusher, B.S.2
Bodner, A.3
Dal Canto, M.4
Wozniak, K.5
Thomas, A.G.6
Rojas, C.7
Tsukamoto, T.8
Majer, P.9
Miller, R.J.10
Monti, A.L.11
Roos, R.P.12
-
26
-
-
27844479654
-
Memantine prolongs survival in an amyotrophic lateral sclerosis mouse model
-
DOI 10.1111/j.1460-9568.2005.04431.x
-
Wang R, Z hang D. M emantine prolongs survival in an amyotrophic lateral sclerosis mouse model. Eur J Neurosci. 2005; 22 : 2376-80 (Pubitemid 41653551)
-
(2005)
European Journal of Neuroscience
, vol.22
, Issue.9
, pp. 2376-2380
-
-
Wang, R.1
Zhang, D.2
-
27
-
-
19944428649
-
β-Lactam antibiotics offer neuroprotection by increasing glutamate transporter expression
-
DOI 10.1038/nature03180
-
Rothstein J D, S arjubhai P, M elissa R, H aenggeli C, Huang Y, Bergles D, et al. Beta-lactam antibiotics offer neuroprotection by increasing glutamate transporter expression. Nature. 2005; 433 : 73-7 (Pubitemid 40101145)
-
(2005)
Nature
, vol.433
, Issue.7021
, pp. 73-77
-
-
Rothstein, J.D.1
Patel, S.2
Regan, M.R.3
Haenggeli, C.4
Huang, Y.H.5
Bergles, D.E.6
Jin, L.7
Hoberg, M.D.8
Vidensky, S.9
Chung, D.S.10
Shuy, V.T.11
Bruijn, L.I.12
Su, Z.-Z.13
Gupta, P.14
Fisher, P.B.15
-
28
-
-
84859718510
-
Lithium lacks effect on survival in amyotrophic lateral sclerosis: A phase IIb randomized sequential trial
-
Verstraete E, V eldink J, H uisman M, D raak T, U ijtendaal E, van der Kooi A.et al. Lithium lacks effect on survival in amyotrophic lateral sclerosis: A phase IIb randomized sequential trial. J Neurol Neurosurg Psychiatry. 2012; 83 : 557-64
-
(2012)
J Neurol Neurosurg Psychiatry
, vol.83
, pp. 557-564
-
-
Verstraete, E.1
Veldink, J.2
Huisman, M.3
Draak, T.4
Uijtendaal, E.5
Van Der Kooi, A.6
-
29
-
-
84892813486
-
-
http://www.alsworldwide.org/ceftriaxone.html
-
-
-
-
30
-
-
77956627546
-
Arandomized, placebo-controlled trial of memantine for functional disability in amyotrophic lateral sclerosis
-
de Carvalho M, P into S, C osta J, E vangelista T, O hana B, Pinto A. A randomized, placebo-controlled trial of memantine for functional disability in amyotrophic lateral sclerosis. Amyotroph Lateral Scler. 2010; 11 : 456-60
-
(2010)
Amyotroph Lateral Scler
, vol.11
, pp. 456-460
-
-
De Carvalho, M.1
Pinto, S.2
Costa, J.3
Evangelista, T.4
Ohana, B.5
Pinto, A.6
-
31
-
-
0038723463
-
A double-blind randomized clinical trial in amyotrophic lateral sclerosis using lamotrigine: Effects on CSF glutamate, aspartate, branched-chain amino acid levels and clinical parameters
-
DOI 10.1034/j.1600-0404.2003.00111.x
-
Ryberg H, A skmark H, P ersson L. A double-blind randomized clinical trial in amyotrophic lateral sclerosis using lamotrigine:Effects on CSF glutamate, aspartate, branchedchain amino acid levels and clinical parameters. Acta Neurol Scand. 2003; 108 : 1-8 (Pubitemid 36791985)
-
(2003)
Acta Neurologica Scandinavica
, vol.108
, Issue.1
, pp. 1-8
-
-
Ryberg, H.1
Askmark, H.2
Persson, L.I.3
-
32
-
-
0035836649
-
Phase III randomized trial of gabapentin in patients with amyotrophic lateral sclerosis
-
Miller R G, M oore D H, G elinas D, D ronsky V, M endoza M, Barohn R.et al. Phase III randomized trial of gabapentin in patients with amyotrophic lateral sclerosis. Neurology. 2001; 56 : 843-8 (Pubitemid 32293584)
-
(2001)
Neurology
, vol.56
, Issue.7
, pp. 843-848
-
-
Miller, R.G.1
Moore II, D.H.2
Gelinas, D.F.3
Dronsky, V.4
Mendoza, M.5
Barohn, R.J.6
Bryan, W.7
Ravits, J.8
Yuen, E.9
Neville, H.10
Ringel, S.11
Bromberg, M.12
Petajan, J.13
Amato, A.A.14
Jackson, C.15
Johnson, W.16
Mandler, R.17
Bosch, P.18
Smith, B.19
Graves, M.20
Ross, M.21
Sorenson, E.J.22
Kelkar, P.23
Parry, G.24
Olney, R.25
more..
-
33
-
-
28644443994
-
Phytochemical assays of commercial botanical dietary supplements
-
Krochmal R, H ardy M, B owerman S, L u Q, W ang H, Elashoff R, Heber D. Phytochemical assays of commercial botanical dietary supplements, eCAM. 2004 ; 1 : 305-13
-
(2004)
ECAM
, vol.1
, pp. 305-313
-
-
Krochmal, R.1
Hardy, M.2
Bowerman, S.3
Lu, Q.4
Wang, H.5
Elashoff, R.6
Heber, D.7
-
34
-
-
84892820339
-
-
http://www.iom.edu/Activities/Nutrition/SummaryDRIs/? / media/Files/Activity%20Files/Nutrition/DRIs/5-Summary% 20Table%20Tables%201-4. pdf
-
-
-
|