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Volumn 53, Issue 4, 2013, Pages 427-434

CYP2C83 polymorphism and donor age are associated with allograft dysfunction in kidney transplant recipients treated with calcineurin inhibitors

Author keywords

ABCB1; Anticalcineurin inhibitors; CYP2C8; Polymorphisms; Renal transplant

Indexed keywords

CALCINEURIN INHIBITOR; CREATININE; CYCLOSPORIN; CYTOCHROME P450 2C8; CYTOCHROME P450 2J2; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; TACROLIMUS; ABCB1 PROTEIN, HUMAN; CALCINEURIN; CYP2C8 PROTEIN, HUMAN; MULTIDRUG RESISTANCE PROTEIN; UNSPECIFIC MONOOXYGENASE;

EID: 84877860571     PISSN: 00912700     EISSN: 15524604     Source Type: Journal    
DOI: 10.1002/jcph.15     Document Type: Article
Times cited : (18)

References (40)
  • 1
    • 0033588034 scopus 로고    scopus 로고
    • Anti-inflammatory properties of cytochrome p450 epoxygenase-derived eicosanoids
    • Node K, Huo Y, Ruan X, et al. Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids. Science. 1999;285:1276-1279.
    • (1999) Science , vol.285 , pp. 1276-1279
    • Node, K.1    Huo, Y.2    Ruan, X.3
  • 2
    • 0030889716 scopus 로고    scopus 로고
    • The role of the cytochrome p450-dependent metabolites of arachidonic acid in blood pressure regulation and renal function: A review
    • Rahman M, Wright JT, Jr., Douglas JG. The role of the cytochrome P450-dependent metabolites of arachidonic acid in blood pressure regulation and renal function: a review. Am J Hypertens. 1997;10: 356-365.
    • (1997) Am J Hypertens , vol.10 , pp. 356-365
    • Rahman, M.1    Wright Jr., J.T.2    Douglas, J.G.3
  • 3
    • 0036277938 scopus 로고    scopus 로고
    • Neuroprotection and p450 2c11 upregulation after experimental transient ischemic attack
    • Alkayed NJ, Goyagi T, Joh HD, et al. Neuroprotection and P450 2C11 upregulation after experimental transient ischemic attack. Stroke. 2002;33:1677-1684.
    • (2002) Stroke , vol.33 , pp. 1677-1684
    • Alkayed, N.J.1    Goyagi, T.2    Joh, H.D.3
  • 4
    • 0035674963 scopus 로고    scopus 로고
    • Cyclic stretch enhances the expression and activity of coronary endothelium-derived hyperpolarizing factor synthase
    • Fisslthaler B, Popp R, Michaelis UR, Kiss L, Fleming I, Busse R. Cyclic stretch enhances the expression and activity of coronary endothelium-derived hyperpolarizing factor synthase. Hypertension. 2001;38:1427-1432.
    • (2001) Hypertension , vol.38 , pp. 1427-1432
    • Fisslthaler, B.1    Popp, R.2    Michaelis, U.R.3    Kiss, L.4    Fleming, I.5    Busse, R.6
  • 5
    • 0028321518 scopus 로고
    • Cytochrome p-450 mediates tissue-damaging hydroxyl radical formation during reoxygenation of the kidney
    • Paller MS, Jacob HS. Cytochrome P-450 mediates tissue-damaging hydroxyl radical formation during reoxygenation of the kidney. Proc Natl Acad Sci USA. 1994;91:7002-7006.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 7002-7006
    • Paller, M.S.1    Jacob, H.S.2
  • 6
    • 0029889723 scopus 로고    scopus 로고
    • Biochemical characterization of the human liver cytochrome p450 arachidonic acid epoxygenase pathway
    • Zeldin DC, Moomaw CR, Jesse N, et al. Biochemical characterization of the human liver cytochrome P450 arachidonic acid epoxygenase pathway. Arch Biochem Biophys. 1996;330:87-96.
    • (1996) Arch Biochem Biophys , vol.330 , pp. 87-96
    • Zeldin, D.C.1    Moomaw, C.R.2    Jesse, N.3
  • 7
    • 0033993749 scopus 로고    scopus 로고
    • Cytochrome p450 and arachidonic acid bioactivation. Molecular and functional properties of the arachidonate monooxygenase
    • Capdevila JH, Falck JR, Harris RC. Cytochrome P450 and arachidonic acid bioactivation. Molecular and functional properties of the arachidonate monooxygenase. J Lipid Res. 2000;41:163-181.
    • (2000) J Lipid Res , vol.41 , pp. 163-181
    • Capdevila, J.H.1    Falck, J.R.2    Harris, R.C.3
  • 8
    • 0030923112 scopus 로고    scopus 로고
    • Molecular cloning, expression, and functional significance of a cytochrome p450 highly expressed in rat heart myocytes
    • Wu S, Chen W, Murphy E, et al. Molecular cloning, expression, and functional significance of a cytochrome P450 highly expressed in rat heart myocytes. J Biol Chem. 1997;272:12551-12559.
    • (1997) J Biol Chem , vol.272 , pp. 12551-12559
    • Wu, S.1    Chen, W.2    Murphy, E.3
  • 9
    • 0035965327 scopus 로고    scopus 로고
    • Epoxygenase pathways of arachidonic acid metabolism
    • Zeldin DC. Epoxygenase pathways of arachidonic acid metabolism. J Biol Chem. 2001;276:36059-36062.
    • (2001) J Biol Chem , vol.276 , pp. 36059-36062
    • Zeldin, D.C.1
  • 10
    • 0029122098 scopus 로고
    • Molecular cloning, expression and characterization of an endogenous human cytochrome p450 arachidonic acid epoxygenase isoform
    • Zeldin DC, DuBois RN, Falck JR, Capdevila JH. Molecular cloning, expression and characterization of an endogenous human cytochrome P450 arachidonic acid epoxygenase isoform. Arch Biochem Biophys. 1995;322:76-86.
    • (1995) Arch Biochem Biophys , vol.322 , pp. 76-86
    • Zeldin, D.C.1    DuBois, R.N.2    Falck, J.R.3    Capdevila, J.H.4
  • 11
    • 77957831701 scopus 로고    scopus 로고
    • Endothelial expression of human cytochrome p450 epoxygenases lowers blood pressure and attenuates hypertension-induced renal injury in mice
    • Lee CR, Imig JD, Edin ML, et al. Endothelial expression of human cytochrome P450 epoxygenases lowers blood pressure and attenuates hypertension-induced renal injury in mice. FASEB J. 2010;24:3770-3781.
    • (2010) FASEB J , vol.24 , pp. 3770-3781
    • Lee, C.R.1    Imig, J.D.2    Edin, M.L.3
  • 12
    • 0034791777 scopus 로고    scopus 로고
    • Polymorphisms in human cyp2c8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid
    • Dai D, Zeldin DC, Blaisdell JA, et al. Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid. Pharmacogenetics. 2001;11:597-607.
    • (2001) Pharmacogenetics , vol.11 , pp. 597-607
    • Dai, D.1    Zeldin, D.C.2    Blaisdell, J.A.3
  • 13
    • 18344377326 scopus 로고    scopus 로고
    • Cloning of cyp2j2 gene and identification of functional polymorphisms
    • King LM, Ma J, Srettabunjong S, et al. Cloning of CYP2J2 gene and identification of functional polymorphisms. Mol Pharmacol. 2002;61:840-852.
    • (2002) Mol Pharmacol , vol.61 , pp. 840-852
    • King, L.M.1    Ma, J.2    Srettabunjong, S.3
  • 14
    • 11144300168 scopus 로고    scopus 로고
    • The effect of the cytochrome p450 cyp2c8 polymorphism on the disposition of (r)-ibuprofen enantiomer in healthy subjects
    • Martinez C, Garcia-Martin E, Blanco G, Gamito FJ, Ladero JM, Agundez JA. The effect of the cytochrome P450 CYP2C8 polymorphism on the disposition of (R)-ibuprofen enantiomer in healthy subjects. Br J Clin Pharmacol. 2005;59:62-69.
    • (2005) Br J Clin Pharmacol , vol.59 , pp. 62-69
    • Martinez, C.1    Garcia-Martin, E.2    Blanco, G.3    Gamito, F.J.4    Ladero, J.M.5    Agundez, J.A.6
  • 15
    • 79955481254 scopus 로고    scopus 로고
    • Pharmgkb summary: Cytochrome p450, family 2, subfamily j, polypeptide 2: Cyp2j2
    • Berlin DS, Sangkuhl K, Klein TE, Altman RB. PharmGKB summary: cytochrome P450, family 2, subfamily J, polypeptide 2: CYP2J2. Pharmacogenet Genomics. 2010;21:308-311.
    • (2010) Pharmacogenet Genomics , vol.21 , pp. 308-311
    • Berlin, D.S.1    Sangkuhl, K.2    Klein, T.E.3    Altman, R.B.4
  • 16
    • 80054712257 scopus 로고    scopus 로고
    • Diagnosis and prevention of chronic kidney allograft loss
    • Nankivell BJ, Kuypers DR. Diagnosis and prevention of chronic kidney allograft loss. Lancet. 2011;378:1428-1437.
    • (2011) Lancet , vol.378 , pp. 1428-1437
    • Nankivell, B.J.1    Kuypers, D.R.2
  • 17
    • 84857192742 scopus 로고    scopus 로고
    • Delayed graft function in the kidney transplant
    • Siedlecki A, Irish W, Brennan DC. Delayed graft function in the kidney transplant. Am J Transplant. 2011;11:2279-2296.
    • (2011) Am J Transplant , vol.11 , pp. 2279-2296
    • Siedlecki, A.1    Irish, W.2    Brennan, D.C.3
  • 18
    • 75149136028 scopus 로고    scopus 로고
    • Pathological and clinical characterization of the 'troubled transplant': Data from the dekaf study
    • Gourishankar S, Leduc R, Connett J, et al. Pathological and clinical characterization of the 'troubled transplant': data from the DeKAF study. Am J Transplant. 2010;10:324-330.
    • (2010) Am J Transplant , vol.10 , pp. 324-330
    • Gourishankar, S.1    Leduc, R.2    Connett, J.3
  • 19
    • 56149085504 scopus 로고    scopus 로고
    • Role of cytochrome p450 2c8 and 2j2 genotypes in calcineurin inhibitor-induced chronic kidney disease
    • Smith HE, Jones JP III, Kalhorn TF, et al. Role of cytochrome P450 2C8 and 2J2 genotypes in calcineurin inhibitor-induced chronic kidney disease. Pharmacogenet Genomics. 2008;18:943-953.
    • (2008) Pharmacogenet Genomics , vol.18 , pp. 943-953
    • Smith, H.E.1    Jones III, J.P.2    Kalhorn, T.F.3
  • 20
    • 0026662551 scopus 로고
    • Cytochrome p-450 3a enzymes are responsible for biotransformation of fk506 and rapamycin in man and rat
    • Sattler M, Guengerich FP, Yun CH, Christians U, Sewing KF. Cytochrome P-450 3A enzymes are responsible for biotransformation of FK506 and rapamycin in man and rat. Drug Metab Dispos. 1992;20:753-761.
    • (1992) Drug Metab Dispos , vol.20 , pp. 753-761
    • Sattler, M.1    Guengerich, F.P.2    Yun, C.H.3    Christians, U.4    Sewing, K.F.5
  • 21
    • 0023921505 scopus 로고
    • Cyclosporine metabolism in human liver: Identification of a cytochrome p-450iii gene family as the major cyclosporine-metabolizing enzyme explains interactions of cyclosporine with other drugs
    • Kronbach T, Fischer V, Meyer UA. Cyclosporine metabolism in human liver: identification of a cytochrome P-450III gene family as the major cyclosporine-metabolizing enzyme explains interactions of cyclosporine with other drugs. Clin Pharmacol Ther. 1988;43: 630-635.
    • (1988) Clin Pharmacol Ther , vol.43 , pp. 630-635
    • Kronbach, T.1    Fischer, V.2    Meyer, U.A.3
  • 22
    • 0242332169 scopus 로고    scopus 로고
    • Impact of cytochrome p450 3a5 genetic polymorphism on tacrolimus doses and concentrationto-dose ratio in renal transplant recipients
    • Thervet E, Anglicheau D, King B, et al. Impact of cytochrome p450 3A5 genetic polymorphism on tacrolimus doses and concentrationto-dose ratio in renal transplant recipients. Transplantation. 2003;76:1233-1235.
    • (2003) Transplantation , vol.76 , pp. 1233-1235
    • Thervet, E.1    Anglicheau, D.2    King, B.3
  • 23
    • 77249158801 scopus 로고    scopus 로고
    • Effect of cyp3a and abcb1 single nucleotide polymorphisms on the pharmacokinetics and pharmacodynamics of calcineurin inhibitors: Part i
    • Staatz CE, Goodman LK, Tett SE. Effect of CYP3A and ABCB1 single nucleotide polymorphisms on the pharmacokinetics and pharmacodynamics of calcineurin inhibitors: Part I. Clin Pharmacokinet. 2010;49:141-175.
    • (2010) Clin Pharmacokinet , vol.49 , pp. 141-175
    • Staatz, C.E.1    Goodman, L.K.2    Tett, S.E.3
  • 24
    • 77249125964 scopus 로고    scopus 로고
    • Effect of cyp3a and abcb1 single nucleotide polymorphisms on the pharmacokinetics and pharmacodynamics of calcineurin inhibitors: Part ii
    • Staatz CE, Goodman LK, Tett SE. Effect of CYP3A and ABCB1 single nucleotide polymorphisms on the pharmacokinetics and pharmacodynamics of calcineurin inhibitors: Part II. Clin Pharmacokinet. 2010;49:207-221.
    • (2010) Clin Pharmacokinet , vol.49 , pp. 207-221
    • Staatz, C.E.1    Goodman, L.K.2    Tett, S.E.3
  • 25
    • 0027418815 scopus 로고
    • Human p-glycoprotein transports cyclosporin a and fk506
    • Saeki T, Ueda K, Tanigawara Y, Hori R, Komano T. Human P-glycoprotein transports cyclosporin A and FK506. J Biol Chem. 1993;268:6077-6080.
    • (1993) J Biol Chem , vol.268 , pp. 6077-6080
    • Saeki, T.1    Ueda, K.2    Tanigawara, Y.3    Hori, R.4    Komano, T.5
  • 26
    • 0035130778 scopus 로고    scopus 로고
    • Detection of mboii polymorphism at the 50 promoter region of cyp3a4
    • Cavalli SA, Hirata MH, Hirata RD. Detection of MboII polymorphism at the 50 promoter region of CYP3A4. Clin Chem. 2001; 47:348-351.
    • (2001) Clin Chem , vol.47 , pp. 348-351
    • Cavalli, S.A.1    Hirata, M.H.2    Hirata, R.D.3
  • 28
    • 0038304548 scopus 로고    scopus 로고
    • Association of the multidrug resistance-1 gene single-nucleotide polymorphisms with the tacrolimus dose requirements in renal transplant recipients
    • Anglicheau D, Verstuyft C, Laurent-Puig P, et al. Association of the multidrug resistance-1 gene single-nucleotide polymorphisms with the tacrolimus dose requirements in renal transplant recipients. J Am Soc Nephrol. 2003;14:1889-1896.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 1889-1896
    • Anglicheau, D.1    Verstuyft, C.2    Laurent-Puig, P.3
  • 29
    • 77955497262 scopus 로고    scopus 로고
    • The risk factors of delayed graft function and comparison of clinical outcomes after deceased donor kidney transplantation: Single-center study
    • Jung GO, Yoon MR, Kim SJ, et al. The risk factors of delayed graft function and comparison of clinical outcomes after deceased donor kidney transplantation: single-center study. Transplant Proc. 2010; 42:705-709.
    • (2010) Transplant Proc , vol.42 , pp. 705-709
    • Jung, G.O.1    Yoon, M.R.2    Kim, S.J.3
  • 30
    • 0029810565 scopus 로고    scopus 로고
    • Adverse effect of donor vasopressor support on immediate and one-year kidney allograft function
    • discussion 6
    • Marshall R, Ahsan N, Dhillon S, Holman M, Yang HC. Adverse effect of donor vasopressor support on immediate and one-year kidney allograft function. Surgery. 1996;120:663-665; discussion 6.
    • (1996) Surgery , vol.120 , pp. 663-665
    • Marshall, R.1    Ahsan, N.2    Dhillon, S.3    Holman, M.4    Yang, H.C.5
  • 31
    • 84858438174 scopus 로고    scopus 로고
    • Impact of genetic polymorphisms on tacrolimus pharmacokinetics and the clinical outcome of renal transplantation
    • Gervasini G, Garcia M, Macias RM, Cubero JJ, Caravaca F, Benitez J. Impact of genetic polymorphisms on tacrolimus pharmacokinetics and the clinical outcome of renal transplantation. Transpl Int. 2012;25:471-480.
    • (2012) Transpl Int , vol.25 , pp. 471-480
    • Gervasini, G.1    Garcia, M.2    Macias, R.M.3    Cubero, J.J.4    Caravaca, F.5    Benitez, J.6
  • 32
    • 1842430562 scopus 로고    scopus 로고
    • Distribution of soluble epoxide hydrolase and of cytochrome p450 2c8, 2c9, and 2j2 in human tissues
    • Enayetallah AE, French RA, Thibodeau MS, Grant DF. Distribution of soluble epoxide hydrolase and of cytochrome P450 2C8, 2C9, and 2J2 in human tissues. J Histochem Cytochem. 2004;52:447-454.
    • (2004) J Histochem Cytochem , vol.52 , pp. 447-454
    • Enayetallah, A.E.1    French, R.A.2    Thibodeau, M.S.3    Grant, D.F.4
  • 33
    • 70350516381 scopus 로고    scopus 로고
    • Impact of donor-dependent genetic factors on long-term renal graft function
    • Krajewska M, Koscielska-Kasprzak K, Weyde W, et al. Impact of donor-dependent genetic factors on long-term renal graft function. Transplant Proc. 2009;41:2978-2980.
    • (2009) Transplant Proc , vol.41 , pp. 2978-2980
    • Krajewska, M.1    Koscielska-Kasprzak, K.2    Weyde, W.3
  • 34
    • 79953171482 scopus 로고    scopus 로고
    • Polymorphisms in cyp3a5 cyp3a4 and abcb1 are not associated with cyclosporine pharmacokinetics nor with cyclosporine clinical end points after renal transplantation
    • Bouamar R, Hesselink DA, van Schaik RH, et al. Polymorphisms in CYP3A5, CYP3A4, and ABCB1 are not associated with cyclosporine pharmacokinetics nor with cyclosporine clinical end points after renal transplantation. Ther Drug Monit. 2011;33:178-184.
    • (2011) Ther Drug Monit , vol.33 , pp. 178-184
    • Bouamar, R.1    Hesselink, D.A.2    Van Schaik, R.H.3
  • 35
    • 64349098468 scopus 로고    scopus 로고
    • Delayed graft function in renal transplant recipients: Risk factors and impact on 1-year graft function: A single center analysis
    • Bronzatto EJ, da Silva Quadros KR, Santos RL, Alves-Filho G, Mazzali M, Delayed graft function in renal transplant recipients: risk factors and impact on 1-year graft function: a single center analysis. Transplant Proc. 2009;41:849-851.
    • (2009) Transplant Proc , vol.41 , pp. 849-851
    • Bronzatto, E.J.1    Da Silva Quadros, K.R.2    Santos, R.L.3    Alves-Filho, G.4    Mazzali, M.5
  • 36
    • 68949218831 scopus 로고    scopus 로고
    • Factors that predict duration of delayed graft function in cadaveric kidney transplantation
    • Dominguez J, Lira F, Troncoso P, Aravena C, Ortiz M, Gonzalez R. Factors that predict duration of delayed graft function in cadaveric kidney transplantation. Transplant Proc. 2009;41:2668-2669.
    • (2009) Transplant Proc , vol.41 , pp. 2668-2669
    • Dominguez, J.1    Lira, F.2    Troncoso, P.3    Aravena, C.4    Ortiz, M.5    Gonzalez, R.6
  • 37
    • 80053184901 scopus 로고    scopus 로고
    • Cyp3a5 and abcb1 polymorphisms in donor and recipient: Impact on tacrolimus dose requirements and clinical outcome after renal transplantation
    • Glowacki F, Lionet A, Buob D, et al. CYP3A5 and ABCB1 polymorphisms in donor and recipient: impact on Tacrolimus dose requirements and clinical outcome after renal transplantation. Nephrol Dial Transplant. 2011;26:3046-3050.
    • (2011) Nephrol Dial Transplant , vol.26 , pp. 3046-3050
    • Glowacki, F.1    Lionet, A.2    Buob, D.3
  • 38
    • 67449097673 scopus 로고    scopus 로고
    • Abcb1 genotypes predict cyclosporine-related adverse events and kidney allograft outcome
    • Cattaneo D, Ruggenenti P, Baldelli S, et al. ABCB1 genotypes predict cyclosporine-related adverse events and kidney allograft outcome. J Am Soc Nephrol. 2009;20:1404-1415.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 1404-1415
    • Cattaneo, D.1    Ruggenenti, P.2    Baldelli, S.3
  • 39
    • 21444449731 scopus 로고    scopus 로고
    • Abcb1 genotype of the donor but not of the recipient is a major risk factor for cyclosporinerelated nephrotoxicity after renal transplantation
    • Hauser IA, Schaeffeler E, Gauer S, et al. ABCB1 genotype of the donor but not of the recipient is a major risk factor for cyclosporinerelated nephrotoxicity after renal transplantation. J Am Soc Nephrol. 2005;16:1501-1511.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 1501-1511
    • Hauser, I.A.1    Schaeffeler, E.2    Gauer, S.3
  • 40
    • 72049101913 scopus 로고    scopus 로고
    • Donor age and renal p-glycoprotein expression associate with chronic histological damage in renal allografts
    • Naesens M, Lerut E, de Jonge H, Van Damme B, Vanrenterghem Y, Kuypers DR. Donor age and renal P-glycoprotein expression associate with chronic histological damage in renal allografts. J Am Soc Nephrol. 2009;20:2468-2480.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 2468-2480
    • Naesens, M.1    Lerut, E.2    De Jonge, H.3    Van Damme, B.4    Vanrenterghem, Y.5    Kuypers, D.R.6


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